1EFNB

Hiv-1 nef protein in complex with r96i mutant fyn sh3 domain
Total Genus 31
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
31
sequence length
133
structure length
104
Chain Sequence
RPQVPLRPMTYKAAVDLSHFLKEKGGLEGLIHSQRRQDILDLWIYHTQGYFPDWQNYTPGPGVRYPLTFGWCYKLVPVREVLEWRFDSRLAFHHVARELHPEYF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Complex (sh3 domain/viral enhancer)
molecule keywords FYN TYROSINE KINASE
publication title Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain.
pubmed doi rcsb
source organism Homo sapiens
total genus 31
structure length 104
sequence length 133
chains with identical sequence D
ec nomenclature
pdb deposition date 1996-06-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.62.10 Alpha Beta 2-Layer Sandwich Nef Regulatory Factor Nef Regulatory Factor 1efnB00
2NEFA 4D8DB 2XI1A 4EMZB 1EFNB 3IOZA 4ORZB 3IK5A 2XI1B 4U5WA 1AVZA 4NEEC 4EN2B 3RBBA 3REAA 1AVVA 3REBA
chains in the Genus database with same CATH superfamily
2NEFA 4D8DB 2XI1A 4EMZB 1EFNB 3IOZA 4ORZB 3IK5A 2XI1B 4U5WA 1AVZA 4NEEC 4EN2B 3RBBA 3REAA 1AVVA 3REBA
chains in the Genus database with same CATH topology
2NEFA 4D8DB 2XI1A 4EMZB 1EFNB 3IOZA 4ORZB 3IK5A 2XI1B 4U5WA 1AVZA 4NEEC 4EN2B 3RBBA 3REAA 1AVVA 3REBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NEF A;  4D8D B;  2XI1 A;  4EMZ B;  1EFN B;  3IOZ A;  4ORZ B;  3IK5 A;  2XI1 B;  4U5W A;  1AVZ A;  4NEE C;  4EN2 B;  3RBB A;  3REA A;  1AVV A;  3REB A; 
#chains in the Genus database with same CATH topology
 2NEF A;  4D8D B;  2XI1 A;  4EMZ B;  1EFN B;  3IOZ A;  4ORZ B;  3IK5 A;  2XI1 B;  4U5W A;  1AVZ A;  4NEE C;  4EN2 B;  3RBB A;  3REA A;  1AVV A;  3REB A; 
#chains in the Genus database with same CATH homology
 2NEF A;  4D8D B;  2XI1 A;  4EMZ B;  1EFN B;  3IOZ A;  4ORZ B;  3IK5 A;  2XI1 B;  4U5W A;  1AVZ A;  4NEE C;  4EN2 B;  3RBB A;  3REA A;  1AVV A;  3REB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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