1O5E | Genus

Total Genus 21

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	21
sequence length	110
structure length	110
Chain Sequence	PLYPVQVSSADARLMVFDKTEGTWRLLCSSRSNARVAGLSCEEMGFLRALTHSELDVRTAGAAGTSGFFCVDEGRLPHTQRLLEVISVCDCPRGRFLAAICQDCGRRKLP

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 110 atoms

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1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

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110 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Dissecting and designing inhibitor selectivity determinants at the S1 site using an artificial Ala190 protease (Ala190 uPA). pubmed doi rcsb
molecule keywords	Serine protease hepsin
molecule tags	Serine protease, hydrolase
source organism	Homo sapiens
total genus	21
structure length	110
sequence length	110
ec nomenclature	ec 3.4.21.106: Hepsin.
pdb deposition date	2003-09-09

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
L	PF09272	Hepsin-SRCR	Hepsin, SRCR domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.10.250.10	Alpha Beta	Roll	Mac-2 Binding Protein	SRCR-like domain	1o5eL00

1BY2A 3T2NA 1O5EL 2OTTX 1O5FL 5JFBA 2JOPA 2OYAA 5CE1A 2JA4A 1Z8GA 2JP0A 2XRCA 1P57A 2OY3A
chains in the Genus database with same CATH superfamily

1BY2A 3T2NA 1O5EL 2OTTX 1O5FL 5JFBA 2JOPA 2OYAA 5CE1A 2JA4A 1Z8GA 2JP0A 2XRCA 1P57A 2OY3A
chains in the Genus database with same CATH topology

1BY2A 3T2NA 1O5EL 2OTTX 1O5FL 5JFBA 2JOPA 2OYAA 5CE1A 2JA4A 1Z8GA 2JP0A 2XRCA 1P57A 2OY3A
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 1BY2 A;  3T2N A;  1O5E L;  2OTT X;  1O5F L;  5JFB A;  2JOP A;  2OYA A;  5CE1 A;  2JA4 A;  1Z8G A;  2JP0 A;  2XRC A;  1P57 A;  2OY3 A; 
#chains in the Genus database with same CATH topology
 1BY2 A;  3T2N A;  1O5E L;  2OTT X;  1O5F L;  5JFB A;  2JOP A;  2OYA A;  5CE1 A;  2JA4 A;  1Z8G A;  2JP0 A;  2XRC A;  1P57 A;  2OY3 A; 
#chains in the Genus database with same CATH homology
 1BY2 A;  3T2N A;  1O5E L;  2OTT X;  1O5F L;  5JFB A;  2JOP A;  2OYA A;  5CE1 A;  2JA4 A;  1Z8G A;  2JP0 A;  2XRC A;  1P57 A;  2OY3 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1O5EL

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations