1P57A

Extracellular domain of human hepsin
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
110
structure length
110
Chain Sequence
PLYPVQVSSADARLMVFDKTEGTWRLLCSSRSNARVAGLSCEEMGFLRALTHSELDVRTAGAAGTSGFFCVDEGRLPHTQRLLEVISVCDCPRGRFLAAICQDCGRRKLP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Structure of the Extracellular Region of Human Hepsin Reveals a Serine Protease Domain and a Novel Scavenger Receptor Cysteine-Rich (SRCR) Domain
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Serine protease hepsin
total genus 21
structure length 110
sequence length 110
ec nomenclature ec 3.4.21.106: Hepsin.
pdb deposition date 2003-04-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09272 Hepsin-SRCR Hepsin, SRCR domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.250.10 Alpha Beta Roll Mac-2 Binding Protein SRCR-like domain 1p57A00
5CE1A 1P57A 2OTTX 1O5EL 2JOPA 2OYAA 2JP0A 1BY2A 1O5FL 2JA4A 1Z8GA 5JFBA 3T2NA 2XRCA 2OY3A
chains in the Genus database with same CATH superfamily
5CE1A 1P57A 2OTTX 1O5EL 2JOPA 2OYAA 2JP0A 1BY2A 1O5FL 2JA4A 1Z8GA 5JFBA 3T2NA 2XRCA 2OY3A
chains in the Genus database with same CATH topology
5CE1A 1P57A 2OTTX 1O5EL 2JOPA 2OYAA 2JP0A 1BY2A 1O5FL 2JA4A 1Z8GA 5JFBA 3T2NA 2XRCA 2OY3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5CE1 A;  1P57 A;  2OTT X;  1O5E L;  2JOP A;  2OYA A;  2JP0 A;  1BY2 A;  1O5F L;  2JA4 A;  1Z8G A;  5JFB A;  3T2N A;  2XRC A;  2OY3 A; 
#chains in the Genus database with same CATH topology
 5CE1 A;  1P57 A;  2OTT X;  1O5E L;  2JOP A;  2OYA A;  2JP0 A;  1BY2 A;  1O5F L;  2JA4 A;  1Z8G A;  5JFB A;  3T2N A;  2XRC A;  2OY3 A; 
#chains in the Genus database with same CATH homology
 5CE1 A;  1P57 A;  2OTT X;  1O5E L;  2JOP A;  2OYA A;  2JP0 A;  1BY2 A;  1O5F L;  2JA4 A;  1Z8G A;  5JFB A;  3T2N A;  2XRC A;  2OY3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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