1Q25A

Crystal structure of n-terminal 3 domains of ci-mpr
Total Genus 98
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
98
sequence length
428
structure length
428
Chain Sequence
QGAEFPELCSYTWEAVDTKNNMLYKINICGNMGVAQCGPSSAVCMHDLKTDSFHSVGDSLLKTASRSLLEFNTTVNCKQQNHKIQSSITFLCGKTLGTPEFVTATDCVHYFEWRTTAACKKNIFKANKEVPCYAFDRELKKHDLNPLIKTSGAYLVDDSDPDTSLFINVCRDIEVLRASSPQVRVCPTGAAACLVRGDRAFDVGRPQEGLKLVSNDRLVLSYVKEGAGQPDFCDGHSPAVTITFVCPSERREGTIPKLTAKSNCRFEIEWVTEYACHRDYLESRSCSLSSAQHDVAVDLQPLSRVEASDSLFYTSEADEYTYYLSICGGSQAPICNKKDAAVCQVKKADSTQVKVAGRPQNLTLRYSDGDLTLIYFGGEECSSGFQRMSVINFECNQTAGNNGRGAPVFTGEVDCTYFFTWDTKYACV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of uPAR, plasminogen, and sugar-binding sites of the 300 kDa mannose 6-phosphate receptor
pubmed doi rcsb
molecule tags Protein transport,sugar binding protein
source organism Bos taurus
molecule keywords cation-independent mannose 6-phosphate receptor
total genus 98
structure length 428
sequence length 428
ec nomenclature
pdb deposition date 2003-07-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00878 CIMR Cation-independent mannose-6-phosphate receptor repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.130.10 Mainly Beta Distorted Sandwich Cation-dependent Mannose-6-phosphate Receptor; Chain A Mannose-6-phosphate receptor binding domain 1q25A03
2.70.130.10 Mainly Beta Distorted Sandwich Cation-dependent Mannose-6-phosphate Receptor; Chain A Mannose-6-phosphate receptor binding domain 1q25A01
2.70.130.10 Mainly Beta Distorted Sandwich Cation-dependent Mannose-6-phosphate Receptor; Chain A Mannose-6-phosphate receptor binding domain 1q25A02
2L2AA 1KEOA 2L2GA 2CNJD 2M68A 2RL8A 2LVXA 2LLAA 3AIHA 1GP3A 2RL7A 2KVAA 3CY4A 3K42A 1M6PA 2L21A 1GP0A 2RLBA 2KVBA 1C39A 1Q25A 1SZ0A 2V5OA 1SYOA 2N1HA 2L29A 1GQBA 1E6FA 2V5NA 4XQMA 2RL9A 3K41A 3K43A 5IEIA 2M6TA
chains in the Genus database with same CATH superfamily
2L2AA 1KEOA 2L2GA 2CNJD 2M68A 2RL8A 2LVXA 2LLAA 3AIHA 1GP3A 2RL7A 2KVAA 3CY4A 3K42A 1M6PA 2L21A 1GP0A 2RLBA 2KVBA 1C39A 1Q25A 1SZ0A 2V5OA 1SYOA 2N1HA 2L29A 1GQBA 1E6FA 2V5NA 4XQMA 2RL9A 3K41A 3K43A 5IEIA 2M6TA
chains in the Genus database with same CATH topology
2L2AA 1KEOA 2L2GA 2CNJD 2M68A 2RL8A 2LVXA 2LLAA 3AIHA 1GP3A 2RL7A 2KVAA 3CY4A 3K42A 1M6PA 2L21A 1GP0A 2RLBA 2KVBA 1C39A 1Q25A 1SZ0A 2V5OA 1SYOA 2N1HA 2L29A 1GQBA 1E6FA 2V5NA 4XQMA 2RL9A 3K41A 3K43A 5IEIA 2M6TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2L2A A;  1KEO A;  2L2G A;  2CNJ D;  2M68 A;  2RL8 A;  2LVX A;  2LLA A;  3AIH A;  1GP3 A;  2RL7 A;  2KVA A;  3CY4 A;  3K42 A;  1M6P A;  2L21 A;  1GP0 A;  2RLB A;  2KVB A;  1C39 A;  1Q25 A;  1SZ0 A;  2V5O A;  1SYO A;  2N1H A;  2L29 A;  1GQB A;  1E6F A;  2V5N A;  4XQM A;  2RL9 A;  3K41 A;  3K43 A;  5IEI A;  2M6T A; 
#chains in the Genus database with same CATH topology
 2L2A A;  1KEO A;  2L2G A;  2CNJ D;  2M68 A;  2RL8 A;  2LVX A;  2LLA A;  3AIH A;  1GP3 A;  2RL7 A;  2KVA A;  3CY4 A;  3K42 A;  1M6P A;  2L21 A;  1GP0 A;  2RLB A;  2KVB A;  1C39 A;  1Q25 A;  1SZ0 A;  2V5O A;  1SYO A;  2N1H A;  2L29 A;  1GQB A;  1E6F A;  2V5N A;  4XQM A;  2RL9 A;  3K41 A;  3K43 A;  5IEI A;  2M6T A; 
#chains in the Genus database with same CATH homology
 2L2A A;  1KEO A;  2L2G A;  2CNJ D;  2M68 A;  2RL8 A;  2LVX A;  2LLA A;  3AIH A;  1GP3 A;  2RL7 A;  2KVA A;  3CY4 A;  3K42 A;  1M6P A;  2L21 A;  1GP0 A;  2RLB A;  2KVB A;  1C39 A;  1Q25 A;  1SZ0 A;  2V5O A;  1SYO A;  2N1H A;  2L29 A;  1GQB A;  1E6F A;  2V5N A;  4XQM A;  2RL9 A;  3K41 A;  3K43 A;  5IEI A;  2M6T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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