2V5OA

Structure of human igf2r domains 11-14
Total Genus 112
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
112
sequence length
613
structure length
604
Chain Sequence
CQVTNPSTGHLFDLSSLSGRAGFTAAYSEKGLVYMSICGENENCPPGVGACFGQTRISVGKANKRLRYVDQVLQLVYKDGSPCPSKSGLSYKSVISFVCRPEAGPTNRPMLISLDKQTCTLFFSWHTPLACEQATECSVRNGSSIVDLSPLIHRTGGYEAYDESTNPDFYINICQPLNPMHAVPCPAGAAVCKVPIDGPPIDIGRVAGPPILNPIANEIYLNFESSTPCLADNYTSLIAFHCKRGVSMGTPKLLRTSECDFVFEWETPVVCPDEVRMDGCTLTDEQLLYSFNLSSLSTSTFKVTRDSRTYSVGVCTFAVGPEQGGCKDGGVCLLSGTKGASFGRLQSMKLDYRHQDEAVVLSYVNGDRCPPETDDGVPCVFPFIFNGKSYEECIIESRAKLWCSTTADYDRDHEWGFCRHSNSYRTSSIIFKCDEDEDIGRPQVFSEVRGCDVTFEWKTKVVCPPKKLECKFVQKHKTYDLRLLSSLTGSWSLVHNGVSYYINLCQKIYKGPLGCSERASICRRTTTGDVQVLGLVHTQKLGVIGDKVVVTYSKGYPCGGNKTASSVIELTCTKTVGRPAFKRFDIDSCTYYFSWDSRAACAVK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR
publication title Structure and Functional Analysis of the Igf-II/Igf2R Interaction
pubmed doi rcsb
source organism Homo sapiens
molecule tags Receptor
total genus 112
structure length 604
sequence length 613
ec nomenclature
pdb deposition date 2007-07-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00040 fn2 Fibronectin type II domain
A PF00878 CIMR Cation-independent mannose-6-phosphate receptor repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.10.10 Mainly Beta Ribbon Seminal Fluid Protein PDC-109 (Domain B) Fibronectin, type II, collagen-binding 2v5oA04
2.70.130.10 Mainly Beta Distorted Sandwich Cation-dependent Mannose-6-phosphate Receptor; Chain A Mannose-6-phosphate receptor binding domain 2v5oA01
2.70.130.10 Mainly Beta Distorted Sandwich Cation-dependent Mannose-6-phosphate Receptor; Chain A Mannose-6-phosphate receptor binding domain 2v5oA05
2.70.130.10 Mainly Beta Distorted Sandwich Cation-dependent Mannose-6-phosphate Receptor; Chain A Mannose-6-phosphate receptor binding domain 2v5oA03
2.70.130.10 Mainly Beta Distorted Sandwich Cation-dependent Mannose-6-phosphate Receptor; Chain A Mannose-6-phosphate receptor binding domain 2v5oA02
1GXDA 1E6FA 1GP3A 2L29A 1CXWA 1E88A 1GP0A 2LVXA 1J7MA 1GQBA 2CNJD 1KS0A 2L2AA 2LLAA 2KVBA 2KVAA 1SZ0A 1Q25A 3K41A 1SYOA 1KEOA 2RLBA 3CY4A 1M6PA 1CK7A 5IEIA 2FN2A 2L2GA 2L21A 2RL9A 1QO6A 3K43A 1E8BA 3AIHA 2M68A 1EAKA 2M6TA 1PDCA 2V5OA 2RL7A 3MQLA 3M7PA 3K42A 2V5NA 1H8PA 2N1HA 1C39A 2RL8A 4XQMA 1L6JA
chains in the Genus database with same CATH superfamily
1GXDA 1GP3A 1E6ZA 4IBFA 2XD1A 4IBDA 2L29A 4Z2IA 4NZ4A 1GQBA 3L29A 4OJOA 3L28A 4Z2LA 3WD2A 4IBGA 4NYUA 2KVAA 2Y2NA 4IBBA 3L27A 1W1YA 3WX7A 4HMEA 2RLBA 4OUIA 1YU3A 3WD0A 1H0GA 2RTSA 3KS4A 1W1PA 3K43A 4Z2GA 2M68A 1EAKA 1PDCA 4NZ5A 3L25A 4HMCA 1O6IA 4IBEA 3M7PA 1E6RA 2V5NA 1C39A 4Z2JA 1YU4A 4IJEA 2BG1A 4XQMA 4MB3A 2Y2QA 2Y2OA 1YUEA 1CXWA 1E88A 4NY2A 1E6NA 1OGGA 2Y2KA 1KS0A 2L2AA 4Z2HA 1SZ0A 1Q25A 3K41A 3L2AA 1E15A 1SYOA 2Y2LA 3L26A 4NZ3A 4TX8A 5IEIA 1GOIA 1UR8A 4OJPA 2FN2A 2L21A 4GHLA 1E8BA 3AIHA 2M6TA 4GH9A 4QNLA 2RL7A 1W1VA 1YU0A 4OJ5A 3FKEA 2Y2JA 1YU1A 1ED7A 2RL8A 1L6JA 4IJFA 2XD5A 4OJLA 4IBIA 3WD4A 2Y2HA 1E6PA 1GP0A 1J7MA 4HMDA 2CNJD 1YU2A 4NZ1A 5BPVA 2KVBA 3HONA 4IBJA 3CY4A 2JE5A 2JCHA 1CK7A 2FFFB 1GPFA 4NYYA 2RL9A 1QO6A 1H0IA 3WD1A 1UR9A 2Y2GA 2D49A 2IOUA 3K42A 1H8PA 2N1HA 2UWXA 4GHAA 1E6FA 4OJ6A 2Y2IA 3N3FA 4MB4A 1OGBA 2LVXA 2LLAA 3WD3A 4Z2KA 1KEOA 1M6PA 3KS8A 2Y2MA 4IBCA 2L2GA 4LG2A 3HSHA 4IBKA 2V5OA 4MB5A 3MQLA 1W1TA 2Y2PA 1AIWA
chains in the Genus database with same CATH topology
1GXDA 1E6FA 1GP3A 2L29A 1CXWA 1E88A 1GP0A 2LVXA 1J7MA 1GQBA 2CNJD 1KS0A 2L2AA 2LLAA 2KVBA 2KVAA 1SZ0A 1Q25A 3K41A 1SYOA 1KEOA 2RLBA 3CY4A 1M6PA 1CK7A 5IEIA 2FN2A 2L2GA 2L21A 2RL9A 1QO6A 3K43A 1E8BA 3AIHA 2M68A 1EAKA 2M6TA 1PDCA 2V5OA 2RL7A 3MQLA 3M7PA 3K42A 2V5NA 1H8PA 2N1HA 1C39A 2RL8A 4XQMA 1L6JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GXD A;  1E6F A;  1GP3 A;  2L29 A;  1CXW A;  1E88 A;  1GP0 A;  2LVX A;  1J7M A;  1GQB A;  2CNJ D;  1KS0 A;  2L2A A;  2LLA A;  2KVB A;  2KVA A;  1SZ0 A;  1Q25 A;  3K41 A;  1SYO A;  1KEO A;  2RLB A;  3CY4 A;  1M6P A;  1CK7 A;  5IEI A;  2FN2 A;  2L2G A;  2L21 A;  2RL9 A;  1QO6 A;  3K43 A;  1E8B A;  3AIH A;  2M68 A;  1EAK A;  2M6T A;  1PDC A;  2V5O A;  2RL7 A;  3MQL A;  3M7P A;  3K42 A;  2V5N A;  1H8P A;  2N1H A;  1C39 A;  2RL8 A;  4XQM A;  1L6J A; 
#chains in the Genus database with same CATH topology
 1GXD A;  1GP3 A;  1E6Z A;  4IBF A;  2XD1 A;  4IBD A;  2L29 A;  4Z2I A;  4NZ4 A;  1GQB A;  3L29 A;  4OJO A;  3L28 A;  4Z2L A;  3WD2 A;  4IBG A;  4NYU A;  2KVA A;  2Y2N A;  4IBB A;  3L27 A;  1W1Y A;  3WX7 A;  4HME A;  2RLB A;  4OUI A;  1YU3 A;  3WD0 A;  1H0G A;  2RTS A;  3KS4 A;  1W1P A;  3K43 A;  4Z2G A;  2M68 A;  1EAK A;  1PDC A;  4NZ5 A;  3L25 A;  4HMC A;  1O6I A;  4IBE A;  3M7P A;  1E6R A;  2V5N A;  1C39 A;  4Z2J A;  1YU4 A;  4IJE A;  2BG1 A;  4XQM A;  4MB3 A;  2Y2Q A;  2Y2O A;  1YUE A;  1CXW A;  1E88 A;  4NY2 A;  1E6N A;  1OGG A;  2Y2K A;  1KS0 A;  2L2A A;  4Z2H A;  1SZ0 A;  1Q25 A;  3K41 A;  3L2A A;  1E15 A;  1SYO A;  2Y2L A;  3L26 A;  4NZ3 A;  4TX8 A;  5IEI A;  1GOI A;  1UR8 A;  4OJP A;  2FN2 A;  2L21 A;  4GHL A;  1E8B A;  3AIH A;  2M6T A;  4GH9 A;  4QNL A;  2RL7 A;  1W1V A;  1YU0 A;  4OJ5 A;  3FKE A;  2Y2J A;  1YU1 A;  1ED7 A;  2RL8 A;  1L6J A;  4IJF A;  2XD5 A;  4OJL A;  4IBI A;  3WD4 A;  2Y2H A;  1E6P A;  1GP0 A;  1J7M A;  4HMD A;  2CNJ D;  1YU2 A;  4NZ1 A;  5BPV A;  2KVB A;  3HON A;  4IBJ A;  3CY4 A;  2JE5 A;  2JCH A;  1CK7 A;  2FFF B;  1GPF A;  4NYY A;  2RL9 A;  1QO6 A;  1H0I A;  3WD1 A;  1UR9 A;  2Y2G A;  2D49 A;  2IOU A;  3K42 A;  1H8P A;  2N1H A;  2UWX A;  4GHA A;  1E6F A;  4OJ6 A;  2Y2I A;  3N3F A;  4MB4 A;  1OGB A;  2LVX A;  2LLA A;  3WD3 A;  4Z2K A;  1KEO A;  1M6P A;  3KS8 A;  2Y2M A;  4IBC A;  2L2G A;  4LG2 A;  3HSH A;  4IBK A;  2V5O A;  4MB5 A;  3MQL A;  1W1T A;  2Y2P A;  1AIW A; 
#chains in the Genus database with same CATH homology
 1GXD A;  1E6F A;  1GP3 A;  2L29 A;  1CXW A;  1E88 A;  1GP0 A;  2LVX A;  1J7M A;  1GQB A;  2CNJ D;  1KS0 A;  2L2A A;  2LLA A;  2KVB A;  2KVA A;  1SZ0 A;  1Q25 A;  3K41 A;  1SYO A;  1KEO A;  2RLB A;  3CY4 A;  1M6P A;  1CK7 A;  5IEI A;  2FN2 A;  2L2G A;  2L21 A;  2RL9 A;  1QO6 A;  3K43 A;  1E8B A;  3AIH A;  2M68 A;  1EAK A;  2M6T A;  1PDC A;  2V5O A;  2RL7 A;  3MQL A;  3M7P A;  3K42 A;  2V5N A;  1H8P A;  2N1H A;  1C39 A;  2RL8 A;  4XQM A;  1L6J A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...