1FVL | Genus

Total Genus 6

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	6
sequence length	70
structure length	70
Chain Sequence	GEECDCGSPSNPCCDAATCKLRPGAQCADGLCCDQCRFKKKRTICRIARGDFPDDRCTGLSNDCPRWNDL

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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Time for openFile(/file/5d29ac32d056fea708a81c96/pdb.gz): 3524 ms

reading 70 atoms

ModelSet: haveSymmetry:false haveUnitcells:false haveFractionalCoord:false

1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

Default Van der Waals type for model set to Jmol

70 atoms created

ModelSet: autobonding; use autobond=false to not generate bonds automatically

Time for creating model: 42 ms

Adding embedded #jmolscript: select ({0:69});backbone only;select *;

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Blood coagulation inhibitor
publication title	The nuclear magnetic resonance solution structure of flavoridin, an antagonist of the platelet GP IIb-IIIa receptor. pubmed doi rcsb
molecule keywords	FLAVORIDIN
total genus	6
structure length	70
sequence length	70
ec nomenclature
pdb deposition date	1995-09-06

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
4.10.70.10	Few Secondary Structures	Irregular	Echistatin	Disintegrin domain	1fvlA00

4M4CA 1TEJB 3C05A 4RQGA 1Q7JA 1FVLA 2PJIA 2M7FA 2LJVA 2M75A 4R5RA 2W9OA 3C05B 2M7HA 1RMRA 1J2LA 2ECHA 1Q7IA 2PJGA 1TEJA 2MP51 1N4YA 1Z1XA 1RO3A 2MOP1 3G5CA 1L3XA 4R5UA 2PJFA 3UCIA 1MPZA 2W9WA 2W9VA 2W9UA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 4M4C A;  1TEJ B;  3C05 A;  4RQG A;  1Q7J A;  1FVL A;  2PJI A;  2M7F A;  2LJV A;  2M75 A;  4R5R A;  2W9O A;  3C05 B;  2M7H A;  1RMR A;  1J2L A;  2ECH A;  1Q7I A;  2PJG A;  1TEJ A;  2MP5 1;  1N4Y A;  1Z1X A;  1RO3 A;  2MOP 1;  3G5C A;  1L3X A;  4R5U A;  2PJF A;  3UCI A;  1MPZ A;  2W9W A;  2W9V A;  2W9U A; 
#chains in the Genus database with same CATH topology
 4M4C A;  1TEJ B;  3C05 A;  4RQG A;  1Q7J A;  1FVL A;  2PJI A;  2M7F A;  2LJV A;  2M75 A;  4R5R A;  2W9O A;  3C05 B;  2M7H A;  1RMR A;  1J2L A;  2ECH A;  1Q7I A;  2PJG A;  1TEJ A;  2MP5 1;  1N4Y A;  1Z1X A;  1RO3 A;  2MOP 1;  3G5C A;  1L3X A;  4R5U A;  2PJF A;  3UCI A;  1MPZ A;  2W9W A;  2W9V A;  2W9U A; 
#chains in the Genus database with same CATH homology
 4M4C A;  1TEJ B;  3C05 A;  4RQG A;  1Q7J A;  1FVL A;  2PJI A;  2M7F A;  2LJV A;  2M75 A;  4R5R A;  2W9O A;  3C05 B;  2M7H A;  1RMR A;  1J2L A;  2ECH A;  1Q7I A;  2PJG A;  1TEJ A;  2MP5 1;  1N4Y A;  1Z1X A;  1RO3 A;  2MOP 1;  3G5C A;  1L3X A;  4R5U A;  2PJF A;  3UCI A;  1MPZ A;  2W9W A;  2W9V A;  2W9U A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1FVLA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN