2A63A

Solution structure of a stably monomeric mutant of lambda cro produced by substitutions in the ball-and-socket interface
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
66
structure length
66
Chain Sequence
MEQRITLKDYAMRFGQTKTAKDLGVQQSAINKWIHAGRKIFLTINADGSVYAEEVKPDPSNKKTTA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Trade between Similar but Nonequivalent Intrasubunit and Intersubunit Contacts in Cro Dimer Evolution.
pubmed doi rcsb
molecule keywords Regulatory protein cro
molecule tags Viral protein
source organism Enterobacteria phage lambda
total genus 12
structure length 66
sequence length 66
ec nomenclature
pdb deposition date 2005-07-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09048 Cro Cro
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.240.10 Alpha Beta 2-Layer Sandwich CRO Repressor CRO Repressor 2a63A00
2ORCA 1D1LA 1COPD 2ECSA 6CROA 1ORCA 2CW1A 1D1MA 2OVGA 5CROA 2A63A 3ORCA
chains in the Genus database with same CATH superfamily
2LJYA 2LJXA 2FK4A 1WU7A 2ORCA 4GIZC 2ECSA 4XR8F 1ORCA 1D1MA 2M3LA 3C6FA 1D1LA 1COPD 6CROA 2CW1A 2OVGA 5CROA 2LJZA 2A63A 3ORCA
chains in the Genus database with same CATH topology
2LJYA 2LJXA 2FK4A 1WU7A 2ORCA 4GIZC 2ECSA 4XR8F 1ORCA 1D1MA 2M3LA 1D1LA 1COPD 6CROA 2CW1A 2OVGA 5CROA 2LJZA 2A63A 3ORCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ORC A;  1D1L A;  1COP D;  2ECS A;  6CRO A;  1ORC A;  2CW1 A;  1D1M A;  2OVG A;  5CRO A;  2A63 A;  3ORC A; 
#chains in the Genus database with same CATH topology
 2LJY A;  2LJX A;  2FK4 A;  1WU7 A;  2ORC A;  4GIZ C;  2ECS A;  4XR8 F;  1ORC A;  1D1M A;  2M3L A;  3C6F A;  1D1L A;  1COP D;  6CRO A;  2CW1 A;  2OVG A;  5CRO A;  2LJZ A;  2A63 A;  3ORC A; 
#chains in the Genus database with same CATH homology
 2LJY A;  2LJX A;  2FK4 A;  1WU7 A;  2ORC A;  4GIZ C;  2ECS A;  4XR8 F;  1ORC A;  1D1M A;  2M3L A;  1D1L A;  1COP D;  6CRO A;  2CW1 A;  2OVG A;  5CRO A;  2LJZ A;  2A63 A;  3ORC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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