2A63A

Solution structure of a stably monomeric mutant of lambda cro produced by substitutions in the ball-and-socket interface
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
66
structure length
66
Chain Sequence
MEQRITLKDYAMRFGQTKTAKDLGVQQSAINKWIHAGRKIFLTINADGSVYAEEVKPDPSNKKTTA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Trade between Similar but Nonequivalent Intrasubunit and Intersubunit Contacts in Cro Dimer Evolution.
pubmed doi rcsb
molecule tags Viral protein
source organism Enterobacteria phage lambda
molecule keywords Regulatory protein cro
total genus 12
structure length 66
sequence length 66
ec nomenclature
pdb deposition date 2005-07-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09048 Cro Cro
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.240.10 Alpha Beta 2-Layer Sandwich CRO Repressor CRO Repressor 2a63A00
1ORCA 5CROA 3ORCA 2OVGA 2ECSA 1D1LA 1COPD 1D1MA 2CW1A 2ORCA 2A63A 6CROA
chains in the Genus database with same CATH superfamily
4XR8F 1WU7A 2OVGA 1D1LA 2ORCA 2CW1A 2LJZA 4GIZC 1ORCA 2ECSA 3C6FA 1COPD 1D1MA 2A63A 6CROA 2LJXA 5CROA 2FK4A 2LJYA 3ORCA 2M3LA
chains in the Genus database with same CATH topology
4XR8F 1WU7A 2OVGA 1D1LA 2ORCA 2CW1A 2LJZA 4GIZC 1ORCA 2ECSA 1COPD 1D1MA 2A63A 6CROA 2LJXA 5CROA 2FK4A 2LJYA 3ORCA 2M3LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ORC A;  5CRO A;  3ORC A;  2OVG A;  2ECS A;  1D1L A;  1COP D;  1D1M A;  2CW1 A;  2ORC A;  2A63 A;  6CRO A; 
#chains in the Genus database with same CATH topology
 4XR8 F;  1WU7 A;  2OVG A;  1D1L A;  2ORC A;  2CW1 A;  2LJZ A;  4GIZ C;  1ORC A;  2ECS A;  3C6F A;  1COP D;  1D1M A;  2A63 A;  6CRO A;  2LJX A;  5CRO A;  2FK4 A;  2LJY A;  3ORC A;  2M3L A; 
#chains in the Genus database with same CATH homology
 4XR8 F;  1WU7 A;  2OVG A;  1D1L A;  2ORC A;  2CW1 A;  2LJZ A;  4GIZ C;  1ORC A;  2ECS A;  1COP D;  1D1M A;  2A63 A;  6CRO A;  2LJX A;  5CRO A;  2FK4 A;  2LJY A;  3ORC A;  2M3L A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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