2CARA

Crystal structure of human inosine triphosphatase
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
196
structure length
196
Chain Sequence
GSMAASLVGKKIVFVTGNAKKLEEVVQILGDKFPCTLVAQKIDLPEYQGEPDEISIQKCQEAVRQVQGPVLVEDTCLCFNALGGLPGPYIKWFLEKLKPEGLHQLLAGFEDKSAYALCTFALSTGDPSQPVRLFRGRTSGRIVAPRGCQDFGWDPCFQPDGYEQTYAEMPKAEKNAVSHRFRALLELQEYFGSLAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Human Inosine Triphosphatase. Substrate Binding and Implication of the Inosine Triphosphatase Deficiency Mutation P32T.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords INOSINE TRIPHOSPHATE PYROPHOSPHATASE
total genus 66
structure length 196
sequence length 196
chains with identical sequence B
ec nomenclature ec 3.6.1.9: Nucleotide diphosphatase.
pdb deposition date 2005-12-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01725 Ham1p_like Ham1 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.950.10 Alpha Beta Alpha-Beta Complex Maf protein Maf protein 2carA00
4P0UA 3S86A 2ZTIA 2DVOA 3TQUA 1ZWYA 2AMHA 1K7KA 4JHCA 2DVNA 4P0EA 2MJPA 1ZNOA 1U14A 1EX2A 2PYUA 4LU1A 1EXCA 4F95A 1B78A 4HEBA 2P5XA 4BNQA 1U5WA 2I5DA 2CARA 2DVPA 1VP2A 2J4EA 2E5XA 1V7RA 4OO0A 2Q16A
chains in the Genus database with same CATH superfamily
5KVKA 4P0UA 3S86A 2ZTIA 2DVOA 3TQUA 1ZWYA 2AMHA 1K7KA 4JHCA 2DVNA 4CT8A 4P0EA 2MJPA 1ZNOA 1U14A 1EX2A 2PYUA 4LU1A 4UOCA 4CT9A 1EXCA 4UUXA 4F95A 1B78A 4HEBA 2P5XA 4BNQA 1U5WA 2A9SA 2I5DA 2CARA 2DVPA 1VP2A 2J4EA 5KOLA 4CTAB 2E5XA 1V7RA 4OO0A 4CTAA 2Q16A 4UUWA
chains in the Genus database with same CATH topology
4P0UA 3S86A 2ZTIA 2DVOA 3TQUA 1ZWYA 2AMHA 1K7KA 4JHCA 2DVNA 4P0EA 2MJPA 1ZNOA 1U14A 1EX2A 2PYUA 4LU1A 1EXCA 4F95A 1B78A 4HEBA 2P5XA 4BNQA 1U5WA 2I5DA 2CARA 2DVPA 1VP2A 2J4EA 2E5XA 1V7RA 4OO0A 2Q16A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4P0U A;  3S86 A;  2ZTI A;  2DVO A;  3TQU A;  1ZWY A;  2AMH A;  1K7K A;  4JHC A;  2DVN A;  4P0E A;  2MJP A;  1ZNO A;  1U14 A;  1EX2 A;  2PYU A;  4LU1 A;  1EXC A;  4F95 A;  1B78 A;  4HEB A;  2P5X A;  4BNQ A;  1U5W A;  2I5D A;  2CAR A;  2DVP A;  1VP2 A;  2J4E A;  2E5X A;  1V7R A;  4OO0 A;  2Q16 A; 
#chains in the Genus database with same CATH topology
 5KVK A;  4P0U A;  3S86 A;  2ZTI A;  2DVO A;  3TQU A;  1ZWY A;  2AMH A;  1K7K A;  4JHC A;  2DVN A;  4CT8 A;  4P0E A;  2MJP A;  1ZNO A;  1U14 A;  1EX2 A;  2PYU A;  4LU1 A;  4UOC A;  4CT9 A;  1EXC A;  4UUX A;  4F95 A;  1B78 A;  4HEB A;  2P5X A;  4BNQ A;  1U5W A;  2A9S A;  2I5D A;  2CAR A;  2DVP A;  1VP2 A;  2J4E A;  5KOL A;  4CTA B;  2E5X A;  1V7R A;  4OO0 A;  4CTA A;  2Q16 A;  4UUW A; 
#chains in the Genus database with same CATH homology
 4P0U A;  3S86 A;  2ZTI A;  2DVO A;  3TQU A;  1ZWY A;  2AMH A;  1K7K A;  4JHC A;  2DVN A;  4P0E A;  2MJP A;  1ZNO A;  1U14 A;  1EX2 A;  2PYU A;  4LU1 A;  1EXC A;  4F95 A;  1B78 A;  4HEB A;  2P5X A;  4BNQ A;  1U5W A;  2I5D A;  2CAR A;  2DVP A;  1VP2 A;  2J4E A;  2E5X A;  1V7R A;  4OO0 A;  2Q16 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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