2ECSA

Lambda cro mutant q27p/a29s/k32q at 1.4 a in space group c2
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
60
structure length
60
Chain Sequence
MEQRITLKDYAMRFGQTKTAKDLGVYPSSINQAIHAGRKIFLTINADGSVYAEEVKPFPS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Two structures of a lambda Cro variant highlight dimer flexibility but disfavor major dimer distortions upon specific binding of cognate DNA.
pubmed doi rcsb
molecule keywords Phage lambda Cro
molecule tags Transcription
source organism Enterobacteria phage lambda
total genus 17
structure length 60
sequence length 60
chains with identical sequence B
ec nomenclature
pdb deposition date 2007-02-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09048 Cro Cro
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.240.10 Alpha Beta 2-Layer Sandwich CRO Repressor CRO Repressor 2ecsA00
2ORCA 2OVGA 2ECSA 1COPD 3ORCA 1D1LA 1D1MA 5CROA 2A63A 1ORCA 6CROA 2CW1A
chains in the Genus database with same CATH superfamily
2ECSA 3ORCA 1WU7A 2LJZA 1D1LA 1D1MA 2M3LA 2CW1A 4GIZC 5CROA 2FK4A 2A63A 1ORCA 1COPD 2ORCA 2OVGA 4XR8F 3C6FA 2LJXA 2LJYA 6CROA
chains in the Genus database with same CATH topology
2ECSA 3ORCA 1WU7A 2LJZA 1D1LA 1D1MA 2M3LA 2CW1A 4GIZC 5CROA 2FK4A 2A63A 1ORCA 1COPD 2ORCA 2OVGA 4XR8F 2LJXA 2LJYA 6CROA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ORC A;  2OVG A;  2ECS A;  1COP D;  3ORC A;  1D1L A;  1D1M A;  5CRO A;  2A63 A;  1ORC A;  6CRO A;  2CW1 A; 
#chains in the Genus database with same CATH topology
 2ECS A;  3ORC A;  1WU7 A;  2LJZ A;  1D1L A;  1D1M A;  2M3L A;  2CW1 A;  4GIZ C;  5CRO A;  2FK4 A;  2A63 A;  1ORC A;  1COP D;  2ORC A;  2OVG A;  4XR8 F;  3C6F A;  2LJX A;  2LJY A;  6CRO A; 
#chains in the Genus database with same CATH homology
 2ECS A;  3ORC A;  1WU7 A;  2LJZ A;  1D1L A;  1D1M A;  2M3L A;  2CW1 A;  4GIZ C;  5CRO A;  2FK4 A;  2A63 A;  1ORC A;  1COP D;  2ORC A;  2OVG A;  4XR8 F;  2LJX A;  2LJY A;  6CRO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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