2FK4A

Solution structure of the c-terminal zinc binding domain of the hpv16 e6 oncoprotein
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
67
structure length
67
Chain Sequence
AMSYSLYGTTLEQQYNKPLSDLLIRCINCQKPLSPEEKQRHLDKKQRFHNIRGRWTGRCMSCSRSSR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and functional analysis of E6 oncoprotein: insights in the molecular pathways of human papillomavirus-mediated pathogenesis
pubmed doi rcsb
molecule keywords Protein E6
molecule tags Metal binding protein, oncoprotein
source organism Human papillomavirus type 16
total genus 10
structure length 67
sequence length 67
ec nomenclature
pdb deposition date 2006-01-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.240.40 Alpha Beta 2-Layer Sandwich CRO Repressor CRO Repressor 2fk4A00
2LJZA 4GIZC 2M3LA 2LJYA 4XR8F 2LJXA 2FK4A
chains in the Genus database with same CATH superfamily
2LJZA 3C6FA 2CW1A 1D1LA 2ECSA 4XR8F 5CROA 1ORCA 4GIZC 6CROA 2LJYA 2FK4A 1D1MA 2A63A 1WU7A 1COPD 3ORCA 2M3LA 2ORCA 2LJXA 2OVGA
chains in the Genus database with same CATH topology
2LJZA 2CW1A 1D1LA 2ECSA 4XR8F 5CROA 1ORCA 4GIZC 6CROA 2LJYA 2FK4A 1D1MA 2A63A 1WU7A 1COPD 3ORCA 2M3LA 2ORCA 2LJXA 2OVGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LJZ A;  4GIZ C;  2M3L A;  2LJY A;  4XR8 F;  2LJX A;  2FK4 A; 
#chains in the Genus database with same CATH topology
 2LJZ A;  3C6F A;  2CW1 A;  1D1L A;  2ECS A;  4XR8 F;  5CRO A;  1ORC A;  4GIZ C;  6CRO A;  2LJY A;  2FK4 A;  1D1M A;  2A63 A;  1WU7 A;  1COP D;  3ORC A;  2M3L A;  2ORC A;  2LJX A;  2OVG A; 
#chains in the Genus database with same CATH homology
 2LJZ A;  2CW1 A;  1D1L A;  2ECS A;  4XR8 F;  5CRO A;  1ORC A;  4GIZ C;  6CRO A;  2LJY A;  2FK4 A;  1D1M A;  2A63 A;  1WU7 A;  1COP D;  3ORC A;  2M3L A;  2ORC A;  2LJX A;  2OVG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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