2I5DA

Crystal structure of human inosine triphosphate pyrophosphatase
Total Genus 68
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
195
structure length
195
Chain Sequence
HMAASLVGKKIVFVTGNAKKLEEVVQILGDKFPCTLVAQKIDLPEYQGEPDEISIQKCQEAVRQVQGPVLVEDTCLCFNALGGLPGPYIKWFLEKLKPEGLHQLLAGFEDKSAYALCTFALSTGDPSQPVRLFRGRTSGRIVAPRGCQDFGWDPCFQPDGYEQTYAEMPKAEKNAVSHRFRALLELQEYFGSLAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the orthorhombic form of human inosine triphosphate pyrophosphatase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords inosine triphosphate pyrophosphohydrolase
total genus 68
structure length 195
sequence length 195
ec nomenclature ec 3.6.1.9: Nucleotide diphosphatase.
pdb deposition date 2006-08-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01725 Ham1p_like Ham1 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.950.10 Alpha Beta Alpha-Beta Complex Maf protein Maf protein 2i5dA00
4JHCA 2DVOA 2CARA 2DVPA 4BNQA 2ZTIA 4LU1A 2P5XA 1K7KA 1B78A 1EXCA 2DVNA 3TQUA 2Q16A 1VP2A 1V7RA 2E5XA 2I5DA 4HEBA 1U14A 1U5WA 1ZNOA 4P0UA 4F95A 3S86A 2PYUA 2AMHA 1ZWYA 1EX2A 2MJPA 4OO0A 4P0EA 2J4EA
chains in the Genus database with same CATH superfamily
4JHCA 2DVOA 2CARA 4CTAB 2DVPA 4BNQA 4CT9A 2ZTIA 4LU1A 2P5XA 1K7KA 1B78A 1EXCA 2DVNA 4UUWA 3TQUA 4CT8A 2Q16A 1VP2A 1V7RA 2E5XA 4CTAA 2I5DA 5KOLA 4HEBA 1U14A 1U5WA 1ZNOA 4P0UA 4F95A 3S86A 4UOCA 4UUXA 2PYUA 2AMHA 1ZWYA 1EX2A 2MJPA 4OO0A 4P0EA 5KVKA 2A9SA 2J4EA
chains in the Genus database with same CATH topology
4JHCA 2DVOA 2CARA 2DVPA 4BNQA 2ZTIA 4LU1A 2P5XA 1K7KA 1B78A 1EXCA 2DVNA 3TQUA 2Q16A 1VP2A 1V7RA 2E5XA 2I5DA 4HEBA 1U14A 1U5WA 1ZNOA 4P0UA 4F95A 3S86A 2PYUA 2AMHA 1ZWYA 1EX2A 2MJPA 4OO0A 4P0EA 2J4EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JHC A;  2DVO A;  2CAR A;  2DVP A;  4BNQ A;  2ZTI A;  4LU1 A;  2P5X A;  1K7K A;  1B78 A;  1EXC A;  2DVN A;  3TQU A;  2Q16 A;  1VP2 A;  1V7R A;  2E5X A;  2I5D A;  4HEB A;  1U14 A;  1U5W A;  1ZNO A;  4P0U A;  4F95 A;  3S86 A;  2PYU A;  2AMH A;  1ZWY A;  1EX2 A;  2MJP A;  4OO0 A;  4P0E A;  2J4E A; 
#chains in the Genus database with same CATH topology
 4JHC A;  2DVO A;  2CAR A;  4CTA B;  2DVP A;  4BNQ A;  4CT9 A;  2ZTI A;  4LU1 A;  2P5X A;  1K7K A;  1B78 A;  1EXC A;  2DVN A;  4UUW A;  3TQU A;  4CT8 A;  2Q16 A;  1VP2 A;  1V7R A;  2E5X A;  4CTA A;  2I5D A;  5KOL A;  4HEB A;  1U14 A;  1U5W A;  1ZNO A;  4P0U A;  4F95 A;  3S86 A;  4UOC A;  4UUX A;  2PYU A;  2AMH A;  1ZWY A;  1EX2 A;  2MJP A;  4OO0 A;  4P0E A;  5KVK A;  2A9S A;  2J4E A; 
#chains in the Genus database with same CATH homology
 4JHC A;  2DVO A;  2CAR A;  2DVP A;  4BNQ A;  2ZTI A;  4LU1 A;  2P5X A;  1K7K A;  1B78 A;  1EXC A;  2DVN A;  3TQU A;  2Q16 A;  1VP2 A;  1V7R A;  2E5X A;  2I5D A;  4HEB A;  1U14 A;  1U5W A;  1ZNO A;  4P0U A;  4F95 A;  3S86 A;  2PYU A;  2AMH A;  1ZWY A;  1EX2 A;  2MJP A;  4OO0 A;  4P0E A;  2J4E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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