2J4EA

The itp complex of human inosine triphosphatase
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
189
structure length
184
Chain Sequence
AASLVGKKIVFVTGNAKKLEEVVQILGDKFPCTLVAQKIDLPEYQGEPDEISIQKCQEAVRQVQGPVLVEDTCLCFNALGGLPGPYIKWFLEKLKPEGLHQLLAGFEDKSAYALCTFALSTPVRLFRGRTSGRIVAPRGCQDFGWDPCFQPDGYEQTYAEMPKAEKNAVSHRFRALLELQEYFG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Human Inosine Triphosphatase: Substrate Binding and Implication of the Inosine Triphosphatase Deficiency Mutation P32T.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords INOSINE TRIPHOSPHATE PYROPHOSPHATASE
total genus 52
structure length 184
sequence length 189
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 3.6.1.9: Nucleotide diphosphatase.
pdb deposition date 2006-08-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01725 Ham1p_like Ham1 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.950.10 Alpha Beta Alpha-Beta Complex Maf protein Maf protein 2j4eA00
2Q16A 4P0EA 2ZTIA 2DVOA 2CARA 2E5XA 4LU1A 2DVNA 1U5WA 1EXCA 3TQUA 1ZWYA 1V7RA 1EX2A 2PYUA 4OO0A 2J4EA 1U14A 4JHCA 1K7KA 4HEBA 2MJPA 2AMHA 4P0UA 4F95A 1ZNOA 1VP2A 2DVPA 2I5DA 4BNQA 1B78A 3S86A 2P5XA
chains in the Genus database with same CATH superfamily
2Q16A 4CT8A 2A9SA 4P0EA 2ZTIA 2DVOA 2CARA 2E5XA 4LU1A 2DVNA 1U5WA 1EXCA 4UUWA 3TQUA 5KVKA 4UUXA 1ZWYA 1V7RA 4CT9A 4UOCA 1EX2A 2PYUA 4OO0A 2J4EA 1U14A 4JHCA 1K7KA 4HEBA 2MJPA 2AMHA 4P0UA 4F95A 1ZNOA 1VP2A 4CTAB 4CTAA 2DVPA 5KOLA 2I5DA 4BNQA 1B78A 3S86A 2P5XA
chains in the Genus database with same CATH topology
2Q16A 4P0EA 2ZTIA 2DVOA 2CARA 2E5XA 4LU1A 2DVNA 1U5WA 1EXCA 3TQUA 1ZWYA 1V7RA 1EX2A 2PYUA 4OO0A 2J4EA 1U14A 4JHCA 1K7KA 4HEBA 2MJPA 2AMHA 4P0UA 4F95A 1ZNOA 1VP2A 2DVPA 2I5DA 4BNQA 1B78A 3S86A 2P5XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Q16 A;  4P0E A;  2ZTI A;  2DVO A;  2CAR A;  2E5X A;  4LU1 A;  2DVN A;  1U5W A;  1EXC A;  3TQU A;  1ZWY A;  1V7R A;  1EX2 A;  2PYU A;  4OO0 A;  2J4E A;  1U14 A;  4JHC A;  1K7K A;  4HEB A;  2MJP A;  2AMH A;  4P0U A;  4F95 A;  1ZNO A;  1VP2 A;  2DVP A;  2I5D A;  4BNQ A;  1B78 A;  3S86 A;  2P5X A; 
#chains in the Genus database with same CATH topology
 2Q16 A;  4CT8 A;  2A9S A;  4P0E A;  2ZTI A;  2DVO A;  2CAR A;  2E5X A;  4LU1 A;  2DVN A;  1U5W A;  1EXC A;  4UUW A;  3TQU A;  5KVK A;  4UUX A;  1ZWY A;  1V7R A;  4CT9 A;  4UOC A;  1EX2 A;  2PYU A;  4OO0 A;  2J4E A;  1U14 A;  4JHC A;  1K7K A;  4HEB A;  2MJP A;  2AMH A;  4P0U A;  4F95 A;  1ZNO A;  1VP2 A;  4CTA B;  4CTA A;  2DVP A;  5KOL A;  2I5D A;  4BNQ A;  1B78 A;  3S86 A;  2P5X A; 
#chains in the Genus database with same CATH homology
 2Q16 A;  4P0E A;  2ZTI A;  2DVO A;  2CAR A;  2E5X A;  4LU1 A;  2DVN A;  1U5W A;  1EXC A;  3TQU A;  1ZWY A;  1V7R A;  1EX2 A;  2PYU A;  4OO0 A;  2J4E A;  1U14 A;  4JHC A;  1K7K A;  4HEB A;  2MJP A;  2AMH A;  4P0U A;  4F95 A;  1ZNO A;  1VP2 A;  2DVP A;  2I5D A;  4BNQ A;  1B78 A;  3S86 A;  2P5X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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