2J4EA

The itp complex of human inosine triphosphatase
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
189
structure length
184
Chain Sequence
AASLVGKKIVFVTGNAKKLEEVVQILGDKFPCTLVAQKIDLPEYQGEPDEISIQKCQEAVRQVQGPVLVEDTCLCFNALGGLPGPYIKWFLEKLKPEGLHQLLAGFEDKSAYALCTFALSTPVRLFRGRTSGRIVAPRGCQDFGWDPCFQPDGYEQTYAEMPKAEKNAVSHRFRALLELQEYFG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Human Inosine Triphosphatase: Substrate Binding and Implication of the Inosine Triphosphatase Deficiency Mutation P32T.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords INOSINE TRIPHOSPHATE PYROPHOSPHATASE
total genus 52
structure length 184
sequence length 189
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 3.6.1.9: Nucleotide diphosphatase.
pdb deposition date 2006-08-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01725 Ham1p_like Ham1 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.950.10 Alpha Beta Alpha-Beta Complex Maf protein Maf protein 2j4eA00
1EX2A 1B78A 4BNQA 2J4EA 1V7RA 2DVNA 1ZWYA 2MJPA 4LU1A 1EXCA 2PYUA 3S86A 2ZTIA 4F95A 2DVOA 2I5DA 1ZNOA 2AMHA 4OO0A 2Q16A 4P0UA 4HEBA 3TQUA 1U5WA 2DVPA 4P0EA 2E5XA 2P5XA 1K7KA 1U14A 2CARA 1VP2A 4JHCA
chains in the Genus database with same CATH superfamily
1EX2A 2A9SA 1B78A 4CTAB 5KVKA 4BNQA 5KOLA 2J4EA 1V7RA 4CT8A 2DVNA 4CT9A 1ZWYA 2MJPA 4LU1A 1EXCA 2PYUA 3S86A 4UOCA 2ZTIA 4F95A 2DVOA 2I5DA 1ZNOA 2AMHA 4OO0A 2Q16A 4P0UA 4HEBA 3TQUA 1U5WA 2DVPA 4P0EA 4CTAA 2E5XA 2P5XA 1K7KA 1U14A 4UUWA 2CARA 1VP2A 4JHCA 4UUXA
chains in the Genus database with same CATH topology
1EX2A 1B78A 4BNQA 2J4EA 1V7RA 2DVNA 1ZWYA 2MJPA 4LU1A 1EXCA 2PYUA 3S86A 2ZTIA 4F95A 2DVOA 2I5DA 1ZNOA 2AMHA 4OO0A 2Q16A 4P0UA 4HEBA 3TQUA 1U5WA 2DVPA 4P0EA 2E5XA 2P5XA 1K7KA 1U14A 2CARA 1VP2A 4JHCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EX2 A;  1B78 A;  4BNQ A;  2J4E A;  1V7R A;  2DVN A;  1ZWY A;  2MJP A;  4LU1 A;  1EXC A;  2PYU A;  3S86 A;  2ZTI A;  4F95 A;  2DVO A;  2I5D A;  1ZNO A;  2AMH A;  4OO0 A;  2Q16 A;  4P0U A;  4HEB A;  3TQU A;  1U5W A;  2DVP A;  4P0E A;  2E5X A;  2P5X A;  1K7K A;  1U14 A;  2CAR A;  1VP2 A;  4JHC A; 
#chains in the Genus database with same CATH topology
 1EX2 A;  2A9S A;  1B78 A;  4CTA B;  5KVK A;  4BNQ A;  5KOL A;  2J4E A;  1V7R A;  4CT8 A;  2DVN A;  4CT9 A;  1ZWY A;  2MJP A;  4LU1 A;  1EXC A;  2PYU A;  3S86 A;  4UOC A;  2ZTI A;  4F95 A;  2DVO A;  2I5D A;  1ZNO A;  2AMH A;  4OO0 A;  2Q16 A;  4P0U A;  4HEB A;  3TQU A;  1U5W A;  2DVP A;  4P0E A;  4CTA A;  2E5X A;  2P5X A;  1K7K A;  1U14 A;  4UUW A;  2CAR A;  1VP2 A;  4JHC A;  4UUX A; 
#chains in the Genus database with same CATH homology
 1EX2 A;  1B78 A;  4BNQ A;  2J4E A;  1V7R A;  2DVN A;  1ZWY A;  2MJP A;  4LU1 A;  1EXC A;  2PYU A;  3S86 A;  2ZTI A;  4F95 A;  2DVO A;  2I5D A;  1ZNO A;  2AMH A;  4OO0 A;  2Q16 A;  4P0U A;  4HEB A;  3TQU A;  1U5W A;  2DVP A;  4P0E A;  2E5X A;  2P5X A;  1K7K A;  1U14 A;  2CAR A;  1VP2 A;  4JHC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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