2LJZA

Structure of the c-terminal domain of hpv16 e6 oncoprotein
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
75
structure length
75
Chain Sequence
GAMSYSLYGTTLEQQYNKPLSDLLIRCINCQKPLSPEEKQRHLDKKQRFHNIRGRWTGRCMSCSRSSRTRRETQL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Solution Structure Analysis of the HPV16 E6 Oncoprotein Reveals a Self-Association Mechanism Required for E6-Mediated Degradation of p53.
pubmed doi rcsb
molecule keywords Protein E6
molecule tags Metal binding protein
source organism Human papillomavirus
total genus 21
structure length 75
sequence length 75
ec nomenclature
pdb deposition date 2011-09-30
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.240.40 Alpha Beta 2-Layer Sandwich CRO Repressor CRO Repressor 2ljzA00
2LJZA 2LJYA 2M3LA 2LJXA 4XR8F 2FK4A 4GIZC
chains in the Genus database with same CATH superfamily
1COPD 1D1MA 2CW1A 4XR8F 2FK4A 2LJZA 2LJYA 2M3LA 3ORCA 6CROA 5CROA 2A63A 4GIZC 2ORCA 1ORCA 1WU7A 2ECSA 2OVGA 3C6FA 2LJXA 1D1LA
chains in the Genus database with same CATH topology
1COPD 1D1MA 2CW1A 4XR8F 2FK4A 2LJZA 2LJYA 2M3LA 3ORCA 6CROA 5CROA 2A63A 4GIZC 2ORCA 1ORCA 1WU7A 2ECSA 2OVGA 2LJXA 1D1LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LJZ A;  2LJY A;  2M3L A;  2LJX A;  4XR8 F;  2FK4 A;  4GIZ C; 
#chains in the Genus database with same CATH topology
 1COP D;  1D1M A;  2CW1 A;  4XR8 F;  2FK4 A;  2LJZ A;  2LJY A;  2M3L A;  3ORC A;  6CRO A;  5CRO A;  2A63 A;  4GIZ C;  2ORC A;  1ORC A;  1WU7 A;  2ECS A;  2OVG A;  3C6F A;  2LJX A;  1D1L A; 
#chains in the Genus database with same CATH homology
 1COP D;  1D1M A;  2CW1 A;  4XR8 F;  2FK4 A;  2LJZ A;  2LJY A;  2M3L A;  3ORC A;  6CRO A;  5CRO A;  2A63 A;  4GIZ C;  2ORC A;  1ORC A;  1WU7 A;  2ECS A;  2OVG A;  2LJX A;  1D1L A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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