2M7HA

The c-terminal region of disintegrin modulate its 3d conformation and cooperate with rgd loop in regulating integrin alpha-iib beta-3 recognition
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
71
structure length
71
Chain Sequence
GKECDCSSPENPCCDAATCKLRPGAQCGEGLCCEQCKFSRAGKICRIARGDWNDDRCTGQSADCPRNPWNG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The C-terminal Region of Disintegrin Modulate its 3D Conformation and Cooperate with RGD Loop in Regulating Recognitions of Integrins
rcsb
molecule keywords Zinc metalloproteinase/disintegrin
molecule tags Hydrolase
source organism Calloselasma rhodostoma
total genus 8
structure length 71
sequence length 71
ec nomenclature ec 3.4.24.-:
pdb deposition date 2013-04-22
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.70.10 Few Secondary Structures Irregular Echistatin Disintegrin domain 2m7hA00
3G5CA 1MPZA 2PJGA 2W9OA 4R5RA 2ECHA 2W9UA 1TEJA 2M7FA 4M4CA 4RQGA 2W9VA 2M7HA 2M75A 3C05A 2PJFA 4R5UA 1RMRA 1Q7JA 2MP51 2PJIA 2W9WA 1Q7IA 1RO3A 1FVLA 1TEJB 1N4YA 1J2LA 3C05B 1L3XA 3UCIA 2MOP1 2LJVA 1Z1XA
chains in the Genus database with same CATH superfamily
3G5CA 1MPZA 2PJGA 2W9OA 4R5RA 2ECHA 2W9UA 1TEJA 2M7FA 4M4CA 4RQGA 2W9VA 2M7HA 2M75A 3C05A 2PJFA 4R5UA 1RMRA 1Q7JA 2MP51 2PJIA 2W9WA 1Q7IA 1RO3A 1FVLA 1TEJB 1N4YA 1J2LA 3C05B 1L3XA 3UCIA 2MOP1 2LJVA 1Z1XA
chains in the Genus database with same CATH topology
3G5CA 1MPZA 2PJGA 2W9OA 4R5RA 2ECHA 2W9UA 1TEJA 2M7FA 4M4CA 4RQGA 2W9VA 2M7HA 2M75A 3C05A 2PJFA 4R5UA 1RMRA 1Q7JA 2MP51 2PJIA 2W9WA 1Q7IA 1RO3A 1FVLA 1TEJB 1N4YA 1J2LA 3C05B 1L3XA 3UCIA 2MOP1 2LJVA 1Z1XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3G5C A;  1MPZ A;  2PJG A;  2W9O A;  4R5R A;  2ECH A;  2W9U A;  1TEJ A;  2M7F A;  4M4C A;  4RQG A;  2W9V A;  2M7H A;  2M75 A;  3C05 A;  2PJF A;  4R5U A;  1RMR A;  1Q7J A;  2MP5 1;  2PJI A;  2W9W A;  1Q7I A;  1RO3 A;  1FVL A;  1TEJ B;  1N4Y A;  1J2L A;  3C05 B;  1L3X A;  3UCI A;  2MOP 1;  2LJV A;  1Z1X A; 
#chains in the Genus database with same CATH topology
 3G5C A;  1MPZ A;  2PJG A;  2W9O A;  4R5R A;  2ECH A;  2W9U A;  1TEJ A;  2M7F A;  4M4C A;  4RQG A;  2W9V A;  2M7H A;  2M75 A;  3C05 A;  2PJF A;  4R5U A;  1RMR A;  1Q7J A;  2MP5 1;  2PJI A;  2W9W A;  1Q7I A;  1RO3 A;  1FVL A;  1TEJ B;  1N4Y A;  1J2L A;  3C05 B;  1L3X A;  3UCI A;  2MOP 1;  2LJV A;  1Z1X A; 
#chains in the Genus database with same CATH homology
 3G5C A;  1MPZ A;  2PJG A;  2W9O A;  4R5R A;  2ECH A;  2W9U A;  1TEJ A;  2M7F A;  4M4C A;  4RQG A;  2W9V A;  2M7H A;  2M75 A;  3C05 A;  2PJF A;  4R5U A;  1RMR A;  1Q7J A;  2MP5 1;  2PJI A;  2W9W A;  1Q7I A;  1RO3 A;  1FVL A;  1TEJ B;  1N4Y A;  1J2L A;  3C05 B;  1L3X A;  3UCI A;  2MOP 1;  2LJV A;  1Z1X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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