2RL7A

Crystal structure cation-dependent mannose 6-phosphate receptor at ph 4.8
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
152
structure length
148
Chain Sequence
EKTCDLVGESEKELALLKRLTPLFQKSFESTVGQSPDMYSYVFRVCREAGQHSSGAGLVQIQKSNGKETVVGRFNETQIFQGSNWIMLIYKGGDEYDNHCGREQRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLACS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights into the Mechanism of pH-dependent Ligand Binding and Release by the Cation-dependent Mannose 6-Phosphate Receptor.
pubmed doi rcsb
molecule tags Protein transport, sugar binding protein
source organism Bos taurus
molecule keywords Cation-dependent mannose-6-phosphate receptor
total genus 36
structure length 148
sequence length 152
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2007-10-18
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.130.10 Mainly Beta Distorted Sandwich Cation-dependent Mannose-6-phosphate Receptor; Chain A Mannose-6-phosphate receptor binding domain 2rl7A00
1C39A 4XQMA 1GQBA 2KVBA 2L2GA 2RL7A 2LVXA 1Q25A 2N1HA 3AIHA 3K41A 2RLBA 1GP3A 5IEIA 1M6PA 2L21A 2L29A 1E6FA 2M68A 2KVAA 1SYOA 2L2AA 2LLAA 2V5NA 2V5OA 3K43A 1SZ0A 2RL8A 3CY4A 3K42A 1GP0A 2CNJD 2M6TA 2RL9A 1KEOA
chains in the Genus database with same CATH superfamily
1C39A 4XQMA 1GQBA 2KVBA 2L2GA 2RL7A 2LVXA 1Q25A 2N1HA 3AIHA 3K41A 2RLBA 1GP3A 5IEIA 1M6PA 2L21A 2L29A 1E6FA 2M68A 2KVAA 1SYOA 2L2AA 2LLAA 2V5NA 2V5OA 3K43A 1SZ0A 2RL8A 3CY4A 3K42A 1GP0A 2CNJD 2M6TA 2RL9A 1KEOA
chains in the Genus database with same CATH topology
1C39A 4XQMA 1GQBA 2KVBA 2L2GA 2RL7A 2LVXA 1Q25A 2N1HA 3AIHA 3K41A 2RLBA 1GP3A 5IEIA 1M6PA 2L21A 2L29A 1E6FA 2M68A 2KVAA 1SYOA 2L2AA 2LLAA 2V5NA 2V5OA 3K43A 1SZ0A 2RL8A 3CY4A 3K42A 1GP0A 2CNJD 2M6TA 2RL9A 1KEOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1C39 A;  4XQM A;  1GQB A;  2KVB A;  2L2G A;  2RL7 A;  2LVX A;  1Q25 A;  2N1H A;  3AIH A;  3K41 A;  2RLB A;  1GP3 A;  5IEI A;  1M6P A;  2L21 A;  2L29 A;  1E6F A;  2M68 A;  2KVA A;  1SYO A;  2L2A A;  2LLA A;  2V5N A;  2V5O A;  3K43 A;  1SZ0 A;  2RL8 A;  3CY4 A;  3K42 A;  1GP0 A;  2CNJ D;  2M6T A;  2RL9 A;  1KEO A; 
#chains in the Genus database with same CATH topology
 1C39 A;  4XQM A;  1GQB A;  2KVB A;  2L2G A;  2RL7 A;  2LVX A;  1Q25 A;  2N1H A;  3AIH A;  3K41 A;  2RLB A;  1GP3 A;  5IEI A;  1M6P A;  2L21 A;  2L29 A;  1E6F A;  2M68 A;  2KVA A;  1SYO A;  2L2A A;  2LLA A;  2V5N A;  2V5O A;  3K43 A;  1SZ0 A;  2RL8 A;  3CY4 A;  3K42 A;  1GP0 A;  2CNJ D;  2M6T A;  2RL9 A;  1KEO A; 
#chains in the Genus database with same CATH homology
 1C39 A;  4XQM A;  1GQB A;  2KVB A;  2L2G A;  2RL7 A;  2LVX A;  1Q25 A;  2N1H A;  3AIH A;  3K41 A;  2RLB A;  1GP3 A;  5IEI A;  1M6P A;  2L21 A;  2L29 A;  1E6F A;  2M68 A;  2KVA A;  1SYO A;  2L2A A;  2LLA A;  2V5N A;  2V5O A;  3K43 A;  1SZ0 A;  2RL8 A;  3CY4 A;  3K42 A;  1GP0 A;  2CNJ D;  2M6T A;  2RL9 A;  1KEO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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