2RLBA

Crystal structure cation-dependent mannose 6-phosphate receptor at ph 6.5 bound to m6p in absence of mn
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
152
structure length
148
Chain Sequence
EKTCDLVGEKGKESEKELALLKRLTPLFQKSFESTVDMYSYVFRVCREAGQHSSGAGLVQIQKSNGKETVVGRFNETQIFQGSNWIMLIYKGGDEYDNHCGREQRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLACS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights into the Mechanism of pH-dependent Ligand Binding and Release by the Cation-dependent Mannose 6-Phosphate Receptor.
pubmed doi rcsb
molecule tags Protein transport, sugar binding protein
source organism Bos taurus
molecule keywords Cation-dependent mannose-6-phosphate receptor
total genus 38
structure length 148
sequence length 152
chains with identical sequence B
ec nomenclature
pdb deposition date 2007-10-18
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.130.10 Mainly Beta Distorted Sandwich Cation-dependent Mannose-6-phosphate Receptor; Chain A Mannose-6-phosphate receptor binding domain 2rlbA00
2V5OA 1GQBA 2RL7A 1GP3A 2KVAA 1Q25A 2L2AA 2RL9A 5IEIA 3K43A 1KEOA 2KVBA 3K41A 3CY4A 2CNJD 2LVXA 1C39A 1GP0A 1SYOA 2LLAA 1SZ0A 3K42A 2RL8A 2L21A 2RLBA 2M68A 2M6TA 2L29A 2L2GA 1E6FA 3AIHA 2N1HA 1M6PA 2V5NA 4XQMA
chains in the Genus database with same CATH superfamily
2V5OA 1GQBA 2RL7A 1GP3A 2KVAA 1Q25A 2L2AA 2RL9A 5IEIA 3K43A 1KEOA 2KVBA 3K41A 3CY4A 2CNJD 2LVXA 1C39A 1GP0A 1SYOA 2LLAA 1SZ0A 3K42A 2RL8A 2L21A 2RLBA 2M68A 2M6TA 2L29A 2L2GA 1E6FA 3AIHA 2N1HA 1M6PA 2V5NA 4XQMA
chains in the Genus database with same CATH topology
2V5OA 1GQBA 2RL7A 1GP3A 2KVAA 1Q25A 2L2AA 2RL9A 5IEIA 3K43A 1KEOA 2KVBA 3K41A 3CY4A 2CNJD 2LVXA 1C39A 1GP0A 1SYOA 2LLAA 1SZ0A 3K42A 2RL8A 2L21A 2RLBA 2M68A 2M6TA 2L29A 2L2GA 1E6FA 3AIHA 2N1HA 1M6PA 2V5NA 4XQMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2V5O A;  1GQB A;  2RL7 A;  1GP3 A;  2KVA A;  1Q25 A;  2L2A A;  2RL9 A;  5IEI A;  3K43 A;  1KEO A;  2KVB A;  3K41 A;  3CY4 A;  2CNJ D;  2LVX A;  1C39 A;  1GP0 A;  1SYO A;  2LLA A;  1SZ0 A;  3K42 A;  2RL8 A;  2L21 A;  2RLB A;  2M68 A;  2M6T A;  2L29 A;  2L2G A;  1E6F A;  3AIH A;  2N1H A;  1M6P A;  2V5N A;  4XQM A; 
#chains in the Genus database with same CATH topology
 2V5O A;  1GQB A;  2RL7 A;  1GP3 A;  2KVA A;  1Q25 A;  2L2A A;  2RL9 A;  5IEI A;  3K43 A;  1KEO A;  2KVB A;  3K41 A;  3CY4 A;  2CNJ D;  2LVX A;  1C39 A;  1GP0 A;  1SYO A;  2LLA A;  1SZ0 A;  3K42 A;  2RL8 A;  2L21 A;  2RLB A;  2M68 A;  2M6T A;  2L29 A;  2L2G A;  1E6F A;  3AIH A;  2N1H A;  1M6P A;  2V5N A;  4XQM A; 
#chains in the Genus database with same CATH homology
 2V5O A;  1GQB A;  2RL7 A;  1GP3 A;  2KVA A;  1Q25 A;  2L2A A;  2RL9 A;  5IEI A;  3K43 A;  1KEO A;  2KVB A;  3K41 A;  3CY4 A;  2CNJ D;  2LVX A;  1C39 A;  1GP0 A;  1SYO A;  2LLA A;  1SZ0 A;  3K42 A;  2RL8 A;  2L21 A;  2RLB A;  2M68 A;  2M6T A;  2L29 A;  2L2G A;  1E6F A;  3AIH A;  2N1H A;  1M6P A;  2V5N A;  4XQM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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