2W9WA

Solution structure of jerdostatin mutant r24k from trimeresurus jerdonii with end c-terminal residues n45g46 deleted
Total Genus 4
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
44
structure length
44
Chain Sequence
AMDCTTGPCCRQCKLKPAGTTCWKTSVSSHYCTGRSCECPSYPG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title NMR Structure and Dynamics of Recombinant Wild-Type and Mutated Jerdostatin, a Selective Inhibitor of Integrin Alpha1 Beta1
pubmed doi rcsb
molecule tags Toxin
source organism Trimeresurus jerdonii
molecule keywords SHORT DISINTEGRIN JERDOSTATIN
total genus 4
structure length 44
sequence length 44
ec nomenclature
pdb deposition date 2009-01-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.70.10 Few Secondary Structures Irregular Echistatin Disintegrin domain 2w9wA00
2M7FA 1TEJB 1J2LA 2PJIA 1FVLA 4R5UA 2LJVA 2PJGA 1Q7IA 2PJFA 3UCIA 2W9UA 3G5CA 4R5RA 2ECHA 3C05A 2MP51 1Q7JA 2W9OA 2M75A 3C05B 1RMRA 4RQGA 1RO3A 1Z1XA 1TEJA 2W9VA 1MPZA 2W9WA 1N4YA 2M7HA 2MOP1 4M4CA 1L3XA
chains in the Genus database with same CATH superfamily
2M7FA 1TEJB 1J2LA 2PJIA 1FVLA 4R5UA 2LJVA 2PJGA 1Q7IA 2PJFA 3UCIA 2W9UA 3G5CA 4R5RA 2ECHA 3C05A 2MP51 1Q7JA 2W9OA 2M75A 3C05B 1RMRA 4RQGA 1RO3A 1Z1XA 1TEJA 2W9VA 1MPZA 2W9WA 1N4YA 2M7HA 2MOP1 4M4CA 1L3XA
chains in the Genus database with same CATH topology
2M7FA 1TEJB 1J2LA 2PJIA 1FVLA 4R5UA 2LJVA 2PJGA 1Q7IA 2PJFA 3UCIA 2W9UA 3G5CA 4R5RA 2ECHA 3C05A 2MP51 1Q7JA 2W9OA 2M75A 3C05B 1RMRA 4RQGA 1RO3A 1Z1XA 1TEJA 2W9VA 1MPZA 2W9WA 1N4YA 2M7HA 2MOP1 4M4CA 1L3XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2M7F A;  1TEJ B;  1J2L A;  2PJI A;  1FVL A;  4R5U A;  2LJV A;  2PJG A;  1Q7I A;  2PJF A;  3UCI A;  2W9U A;  3G5C A;  4R5R A;  2ECH A;  3C05 A;  2MP5 1;  1Q7J A;  2W9O A;  2M75 A;  3C05 B;  1RMR A;  4RQG A;  1RO3 A;  1Z1X A;  1TEJ A;  2W9V A;  1MPZ A;  2W9W A;  1N4Y A;  2M7H A;  2MOP 1;  4M4C A;  1L3X A; 
#chains in the Genus database with same CATH topology
 2M7F A;  1TEJ B;  1J2L A;  2PJI A;  1FVL A;  4R5U A;  2LJV A;  2PJG A;  1Q7I A;  2PJF A;  3UCI A;  2W9U A;  3G5C A;  4R5R A;  2ECH A;  3C05 A;  2MP5 1;  1Q7J A;  2W9O A;  2M75 A;  3C05 B;  1RMR A;  4RQG A;  1RO3 A;  1Z1X A;  1TEJ A;  2W9V A;  1MPZ A;  2W9W A;  1N4Y A;  2M7H A;  2MOP 1;  4M4C A;  1L3X A; 
#chains in the Genus database with same CATH homology
 2M7F A;  1TEJ B;  1J2L A;  2PJI A;  1FVL A;  4R5U A;  2LJV A;  2PJG A;  1Q7I A;  2PJF A;  3UCI A;  2W9U A;  3G5C A;  4R5R A;  2ECH A;  3C05 A;  2MP5 1;  1Q7J A;  2W9O A;  2M75 A;  3C05 B;  1RMR A;  4RQG A;  1RO3 A;  1Z1X A;  1TEJ A;  2W9V A;  1MPZ A;  2W9W A;  1N4Y A;  2M7H A;  2MOP 1;  4M4C A;  1L3X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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