2XI1B

Crystal structure of the hiv-1 nef sequenced from a patient's sample
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
130
structure length
100
Chain Sequence
VPLRPMTYKGAVDLSFFLKEKGGLEGLVYSQKRKEILDLWVYHTQGYFPDWQCYTPGPGVRYPLTFGWCFKLVPVEVLKWKFDSHLAHTHMARELHPEFY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Novel Dimer-Tetramer Transition Captured by the Crystal Structure of the HIV-1 Nef.
pubmed doi rcsb
molecule tags Viral protein
source organism Human immunodeficiency virus type 1 (bh5 isolate)
molecule keywords NEF
total genus 25
structure length 100
sequence length 130
ec nomenclature
pdb deposition date 2010-06-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00469 F-protein Negative factor, (F-Protein) or Nef
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.62.10 Alpha Beta 2-Layer Sandwich Nef Regulatory Factor Nef Regulatory Factor 2xi1B00
3IOZA 4D8DB 4ORZB 3IK5A 2XI1A 4U5WA 1EFNB 4EMZB 1AVVA 4NEEC 3REAA 1AVZA 2XI1B 2NEFA 4EN2B 3REBA 3RBBA
chains in the Genus database with same CATH superfamily
3IOZA 4D8DB 4ORZB 3IK5A 2XI1A 4U5WA 1EFNB 4EMZB 1AVVA 4NEEC 3REAA 1AVZA 2XI1B 2NEFA 4EN2B 3REBA 3RBBA
chains in the Genus database with same CATH topology
3IOZA 4D8DB 4ORZB 3IK5A 2XI1A 4U5WA 1EFNB 4EMZB 1AVVA 4NEEC 3REAA 1AVZA 2XI1B 2NEFA 4EN2B 3REBA 3RBBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3IOZ A;  4D8D B;  4ORZ B;  3IK5 A;  2XI1 A;  4U5W A;  1EFN B;  4EMZ B;  1AVV A;  4NEE C;  3REA A;  1AVZ A;  2XI1 B;  2NEF A;  4EN2 B;  3REB A;  3RBB A; 
#chains in the Genus database with same CATH topology
 3IOZ A;  4D8D B;  4ORZ B;  3IK5 A;  2XI1 A;  4U5W A;  1EFN B;  4EMZ B;  1AVV A;  4NEE C;  3REA A;  1AVZ A;  2XI1 B;  2NEF A;  4EN2 B;  3REB A;  3RBB A; 
#chains in the Genus database with same CATH homology
 3IOZ A;  4D8D B;  4ORZ B;  3IK5 A;  2XI1 A;  4U5W A;  1EFN B;  4EMZ B;  1AVV A;  4NEE C;  3REA A;  1AVZ A;  2XI1 B;  2NEF A;  4EN2 B;  3REB A;  3RBB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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