2M75A

The c-terminal region of disintegrin modulate its 3d conformation and cooperate with rgd loop in regulating recognitions of integrins
Total Genus 7
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
7
sequence length
68
structure length
68
Chain Sequence
GKECDCSSPENPCCDAATCKLRPGAQCGEGLCCEQCKFSRAGKICRIARGDWNDDRCTGQSADCPRYH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The C-terminal Region of Disintegrin Modulate its 3D Conformation and Cooperate with RGD Loop in Regulating Recognitions of Integrins
rcsb
molecule tags Hydrolase
source organism Calloselasma rhodostoma
molecule keywords Zinc metalloproteinase/disintegrin
total genus 7
structure length 68
sequence length 68
ec nomenclature ec 3.4.24.-:
pdb deposition date 2013-04-18
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.70.10 Few Secondary Structures Irregular Echistatin Disintegrin domain 2m75A00
2PJIA 4R5UA 1Z1XA 3C05B 1TEJA 4R5RA 1RO3A 2PJGA 2M75A 1Q7JA 1FVLA 2MP51 2PJFA 1RMRA 3C05A 1L3XA 2W9UA 1Q7IA 1MPZA 2W9OA 2M7FA 1N4YA 2W9WA 3G5CA 2W9VA 3UCIA 2MOP1 1TEJB 2ECHA 4RQGA 1J2LA 2LJVA 4M4CA 2M7HA
chains in the Genus database with same CATH superfamily
2PJIA 4R5UA 1Z1XA 3C05B 1TEJA 4R5RA 1RO3A 2PJGA 2M75A 1Q7JA 1FVLA 2MP51 2PJFA 1RMRA 3C05A 1L3XA 2W9UA 1Q7IA 1MPZA 2W9OA 2M7FA 1N4YA 2W9WA 3G5CA 2W9VA 3UCIA 2MOP1 1TEJB 2ECHA 4RQGA 1J2LA 2LJVA 4M4CA 2M7HA
chains in the Genus database with same CATH topology
2PJIA 4R5UA 1Z1XA 3C05B 1TEJA 4R5RA 1RO3A 2PJGA 2M75A 1Q7JA 1FVLA 2MP51 2PJFA 1RMRA 3C05A 1L3XA 2W9UA 1Q7IA 1MPZA 2W9OA 2M7FA 1N4YA 2W9WA 3G5CA 2W9VA 3UCIA 2MOP1 1TEJB 2ECHA 4RQGA 1J2LA 2LJVA 4M4CA 2M7HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PJI A;  4R5U A;  1Z1X A;  3C05 B;  1TEJ A;  4R5R A;  1RO3 A;  2PJG A;  2M75 A;  1Q7J A;  1FVL A;  2MP5 1;  2PJF A;  1RMR A;  3C05 A;  1L3X A;  2W9U A;  1Q7I A;  1MPZ A;  2W9O A;  2M7F A;  1N4Y A;  2W9W A;  3G5C A;  2W9V A;  3UCI A;  2MOP 1;  1TEJ B;  2ECH A;  4RQG A;  1J2L A;  2LJV A;  4M4C A;  2M7H A; 
#chains in the Genus database with same CATH topology
 2PJI A;  4R5U A;  1Z1X A;  3C05 B;  1TEJ A;  4R5R A;  1RO3 A;  2PJG A;  2M75 A;  1Q7J A;  1FVL A;  2MP5 1;  2PJF A;  1RMR A;  3C05 A;  1L3X A;  2W9U A;  1Q7I A;  1MPZ A;  2W9O A;  2M7F A;  1N4Y A;  2W9W A;  3G5C A;  2W9V A;  3UCI A;  2MOP 1;  1TEJ B;  2ECH A;  4RQG A;  1J2L A;  2LJV A;  4M4C A;  2M7H A; 
#chains in the Genus database with same CATH homology
 2PJI A;  4R5U A;  1Z1X A;  3C05 B;  1TEJ A;  4R5R A;  1RO3 A;  2PJG A;  2M75 A;  1Q7J A;  1FVL A;  2MP5 1;  2PJF A;  1RMR A;  3C05 A;  1L3X A;  2W9U A;  1Q7I A;  1MPZ A;  2W9O A;  2M7F A;  1N4Y A;  2W9W A;  3G5C A;  2W9V A;  3UCI A;  2MOP 1;  1TEJ B;  2ECH A;  4RQG A;  1J2L A;  2LJV A;  4M4C A;  2M7H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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