2M7HA

The c-terminal region of disintegrin modulate its 3d conformation and cooperate with rgd loop in regulating integrin alpha-iib beta-3 recognition
Total Genus 8
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
71
structure length
71
Chain Sequence
GKECDCSSPENPCCDAATCKLRPGAQCGEGLCCEQCKFSRAGKICRIARGDWNDDRCTGQSADCPRNPWNG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title The C-terminal Region of Disintegrin Modulate its 3D Conformation and Cooperate with RGD Loop in Regulating Recognitions of Integrins
rcsb
molecule tags Hydrolase
source organism Calloselasma rhodostoma
molecule keywords Zinc metalloproteinase/disintegrin
total genus 8
structure length 71
sequence length 71
ec nomenclature ec 3.4.24.-:
pdb deposition date 2013-04-22
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.70.10 Few Secondary Structures Irregular Echistatin Disintegrin domain 2m7hA00
4R5UA 4R5RA 1TEJA 3C05B 2W9WA 1N4YA 1RMRA 1RO3A 2PJFA 2PJIA 4RQGA 1TEJB 1FVLA 1Q7IA 2ECHA 1Z1XA 2M7FA 1J2LA 3UCIA 2MOP1 2PJGA 2W9VA 2MP51 2M75A 2LJVA 2M7HA 1L3XA 1MPZA 4M4CA 2W9OA 2W9UA 3G5CA 3C05A 1Q7JA
chains in the Genus database with same CATH superfamily
4R5UA 4R5RA 1TEJA 3C05B 2W9WA 1N4YA 1RMRA 1RO3A 2PJFA 2PJIA 4RQGA 1TEJB 1FVLA 1Q7IA 2ECHA 1Z1XA 2M7FA 1J2LA 3UCIA 2MOP1 2PJGA 2W9VA 2MP51 2M75A 2LJVA 2M7HA 1L3XA 1MPZA 4M4CA 2W9OA 2W9UA 3G5CA 3C05A 1Q7JA
chains in the Genus database with same CATH topology
4R5UA 4R5RA 1TEJA 3C05B 2W9WA 1N4YA 1RMRA 1RO3A 2PJFA 2PJIA 4RQGA 1TEJB 1FVLA 1Q7IA 2ECHA 1Z1XA 2M7FA 1J2LA 3UCIA 2MOP1 2PJGA 2W9VA 2MP51 2M75A 2LJVA 2M7HA 1L3XA 1MPZA 4M4CA 2W9OA 2W9UA 3G5CA 3C05A 1Q7JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4R5U A;  4R5R A;  1TEJ A;  3C05 B;  2W9W A;  1N4Y A;  1RMR A;  1RO3 A;  2PJF A;  2PJI A;  4RQG A;  1TEJ B;  1FVL A;  1Q7I A;  2ECH A;  1Z1X A;  2M7F A;  1J2L A;  3UCI A;  2MOP 1;  2PJG A;  2W9V A;  2MP5 1;  2M75 A;  2LJV A;  2M7H A;  1L3X A;  1MPZ A;  4M4C A;  2W9O A;  2W9U A;  3G5C A;  3C05 A;  1Q7J A; 
#chains in the Genus database with same CATH topology
 4R5U A;  4R5R A;  1TEJ A;  3C05 B;  2W9W A;  1N4Y A;  1RMR A;  1RO3 A;  2PJF A;  2PJI A;  4RQG A;  1TEJ B;  1FVL A;  1Q7I A;  2ECH A;  1Z1X A;  2M7F A;  1J2L A;  3UCI A;  2MOP 1;  2PJG A;  2W9V A;  2MP5 1;  2M75 A;  2LJV A;  2M7H A;  1L3X A;  1MPZ A;  4M4C A;  2W9O A;  2W9U A;  3G5C A;  3C05 A;  1Q7J A; 
#chains in the Genus database with same CATH homology
 4R5U A;  4R5R A;  1TEJ A;  3C05 B;  2W9W A;  1N4Y A;  1RMR A;  1RO3 A;  2PJF A;  2PJI A;  4RQG A;  1TEJ B;  1FVL A;  1Q7I A;  2ECH A;  1Z1X A;  2M7F A;  1J2L A;  3UCI A;  2MOP 1;  2PJG A;  2W9V A;  2MP5 1;  2M75 A;  2LJV A;  2M7H A;  1L3X A;  1MPZ A;  4M4C A;  2W9O A;  2W9U A;  3G5C A;  3C05 A;  1Q7J A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...