3I2BA

The crystal structure of human 6 pyruvoyl tetrahydrobiopterin synthase
Total Genus 33
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
138
structure length
138
Chain Sequence
RRCQAQVSRRISFSASHRLYSKFLSDEENLKLFGKCNNPNGHGHNYKVVVTVHGEIDPATGMVMNLADLKKYMEEAIMQPLDHKNLDMDVPYFADVVSTTENVAVYIWDNLQKVLPVGVLYKVKVYETDNNIVVYKGE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title The crystal structure of human 6 Pyruvoyl Tetrahydrobiopterin Synthase
rcsb
molecule keywords 6-pyruvoyl tetrahydrobiopterin synthase
molecule tags Lyase
source organism Homo sapiens
total genus 33
structure length 138
sequence length 138
chains with identical sequence B, C, D, E, F, G, H, I, J, K, L
ec nomenclature ec 4.2.3.12: 6-pyruvoyltetrahydropterin synthase.
pdb deposition date 2009-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01242 PTPS 6-pyruvoyl tetrahydropterin synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.479.10 Alpha Beta 2-Layer Sandwich Tetrahydropterin Synthase; Chain A Tetrahydropterin Synthase; Chain A 3i2bA00
3M0NA 2A0SA 1B6ZA 1B66A 2DTTA 2G64A 3D7JA 4NTKA 1Y13A 3JYGA 1GTQA 3QN9A 3QN0A 3LZEA 4NTNA 2OBAA 3I2BA 3LX3A 3QNAA 4NTMA 2DJ6A
chains in the Genus database with same CATH superfamily
3M0NA 2A0SA 1B6ZA 1B66A 2DTTA 2G64A 3D7JA 3BK6A 4NTKA 1Y13A 3JYGA 1TFEA 1GTQA 4FVFA 1XB2B 3QN9A 3QN0A 3LZEA 4FVGA 4Q7JA 4NTNA 2OBAA 3I2BA 2RPBA 1AIPC 3LX3A 3QNAA 4FVJA 1EFUB 4NTMA 1WINA 2DJ6A
chains in the Genus database with same CATH topology
3M0NA 2A0SA 1B6ZA 1B66A 2DTTA 2G64A 3D7JA 3BK6A 4NTKA 1Y13A 3JYGA 1GTQA 4FVFA 3QN9A 3QN0A 3LZEA 4FVGA 4NTNA 2OBAA 3I2BA 2RPBA 3LX3A 3QNAA 4FVJA 4NTMA 1WINA 2DJ6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3M0N A;  2A0S A;  1B6Z A;  1B66 A;  2DTT A;  2G64 A;  3D7J A;  4NTK A;  1Y13 A;  3JYG A;  1GTQ A;  3QN9 A;  3QN0 A;  3LZE A;  4NTN A;  2OBA A;  3I2B A;  3LX3 A;  3QNA A;  4NTM A;  2DJ6 A; 
#chains in the Genus database with same CATH topology
 3M0N A;  2A0S A;  1B6Z A;  1B66 A;  2DTT A;  2G64 A;  3D7J A;  3BK6 A;  4NTK A;  1Y13 A;  3JYG A;  1TFE A;  1GTQ A;  4FVF A;  1XB2 B;  3QN9 A;  3QN0 A;  3LZE A;  4FVG A;  4Q7J A;  4NTN A;  2OBA A;  3I2B A;  2RPB A;  1AIP C;  3LX3 A;  3QNA A;  4FVJ A;  1EFU B;  4NTM A;  1WIN A;  2DJ6 A; 
#chains in the Genus database with same CATH homology
 3M0N A;  2A0S A;  1B6Z A;  1B66 A;  2DTT A;  2G64 A;  3D7J A;  3BK6 A;  4NTK A;  1Y13 A;  3JYG A;  1GTQ A;  4FVF A;  3QN9 A;  3QN0 A;  3LZE A;  4FVG A;  4NTN A;  2OBA A;  3I2B A;  2RPB A;  3LX3 A;  3QNA A;  4FVJ A;  4NTM A;  1WIN A;  2DJ6 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...