3K41A

Crystal structure of scd-mpr mutant e19q/k137m bound to man-6-p
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
151
structure length
145
Chain Sequence
KTCDLVSEKQLALLKRLTPLFQKSFESTVGQSPDMYSYVFRVCREAGQHSSGAGLVQIQKSNGKETVVGRFNETQIFQGSNWIMLIYKGGDEYDNHCGREQRRAVVMISCNRHTLADNFNPVSEERGMVQDCFYLFEMDSSLACS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Intermonomer interactions are essential for lysosomal enzyme binding by the cation-dependent mannose 6-phosphate receptor.
pubmed doi rcsb
molecule tags Protein transport, sugar binding protein
source organism Bos taurus
molecule keywords Cation-dependent mannose-6-phosphate receptor
total genus 39
structure length 145
sequence length 151
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-10-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.130.10 Mainly Beta Distorted Sandwich Cation-dependent Mannose-6-phosphate Receptor; Chain A Mannose-6-phosphate receptor binding domain 3k41A00
1E6FA 3AIHA 3CY4A 2CNJD 3K43A 1GP0A 2M6TA 1GQBA 2LVXA 2L2AA 2KVAA 3K42A 4XQMA 1SZ0A 5IEIA 2RL8A 2N1HA 1C39A 2L2GA 2L29A 2RL7A 1KEOA 2LLAA 1SYOA 2RL9A 1M6PA 3K41A 1GP3A 2V5OA 2RLBA 2V5NA 2L21A 2KVBA 1Q25A 2M68A
chains in the Genus database with same CATH superfamily
1E6FA 3AIHA 3CY4A 2CNJD 3K43A 1GP0A 2M6TA 1GQBA 2LVXA 2L2AA 2KVAA 3K42A 4XQMA 1SZ0A 5IEIA 2RL8A 2N1HA 1C39A 2L2GA 2L29A 2RL7A 1KEOA 2LLAA 1SYOA 2RL9A 1M6PA 3K41A 1GP3A 2V5OA 2RLBA 2V5NA 2L21A 2KVBA 1Q25A 2M68A
chains in the Genus database with same CATH topology
1E6FA 3AIHA 3CY4A 2CNJD 3K43A 1GP0A 2M6TA 1GQBA 2LVXA 2L2AA 2KVAA 3K42A 4XQMA 1SZ0A 5IEIA 2RL8A 2N1HA 1C39A 2L2GA 2L29A 2RL7A 1KEOA 2LLAA 1SYOA 2RL9A 1M6PA 3K41A 1GP3A 2V5OA 2RLBA 2V5NA 2L21A 2KVBA 1Q25A 2M68A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1E6F A;  3AIH A;  3CY4 A;  2CNJ D;  3K43 A;  1GP0 A;  2M6T A;  1GQB A;  2LVX A;  2L2A A;  2KVA A;  3K42 A;  4XQM A;  1SZ0 A;  5IEI A;  2RL8 A;  2N1H A;  1C39 A;  2L2G A;  2L29 A;  2RL7 A;  1KEO A;  2LLA A;  1SYO A;  2RL9 A;  1M6P A;  3K41 A;  1GP3 A;  2V5O A;  2RLB A;  2V5N A;  2L21 A;  2KVB A;  1Q25 A;  2M68 A; 
#chains in the Genus database with same CATH topology
 1E6F A;  3AIH A;  3CY4 A;  2CNJ D;  3K43 A;  1GP0 A;  2M6T A;  1GQB A;  2LVX A;  2L2A A;  2KVA A;  3K42 A;  4XQM A;  1SZ0 A;  5IEI A;  2RL8 A;  2N1H A;  1C39 A;  2L2G A;  2L29 A;  2RL7 A;  1KEO A;  2LLA A;  1SYO A;  2RL9 A;  1M6P A;  3K41 A;  1GP3 A;  2V5O A;  2RLB A;  2V5N A;  2L21 A;  2KVB A;  1Q25 A;  2M68 A; 
#chains in the Genus database with same CATH homology
 1E6F A;  3AIH A;  3CY4 A;  2CNJ D;  3K43 A;  1GP0 A;  2M6T A;  1GQB A;  2LVX A;  2L2A A;  2KVA A;  3K42 A;  4XQM A;  1SZ0 A;  5IEI A;  2RL8 A;  2N1H A;  1C39 A;  2L2G A;  2L29 A;  2RL7 A;  1KEO A;  2LLA A;  1SYO A;  2RL9 A;  1M6P A;  3K41 A;  1GP3 A;  2V5O A;  2RLB A;  2V5N A;  2L21 A;  2KVB A;  1Q25 A;  2M68 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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