3QNAA

Crystal structure of a 6-pyruvoyltetrahydropterin synthase homologue from esherichia coli complexed sepiapterin
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
118
structure length
118
Chain Sequence
STTLFKDFTFEAAHRLPHVPEGHKAGRLHGHSFMVRLEITGEVDPHTGWIIDFAELKAAFKPTYERLDHHYLNDIPGLENPTSEVLAKWIWDQVKPVVPLLSAVMVKETCTAGCIYRG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of a novel activity of bacterial 6-pyruvoyltetrahydropterin synthase homologues distinct from mammalian 6-pyruvoyltetrahydropterin synthase activity.
pubmed doi rcsb
molecule tags Lyase
source organism Escherichia coli
molecule keywords 6-carboxy-5,6,7,8-tetrahydropterin synthase
total genus 28
structure length 118
sequence length 118
chains with identical sequence B, C, D, E, F
ec nomenclature ec 4.1.2.50: 6-carboxytetrahydropterin synthase.
pdb deposition date 2011-02-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01242 PTPS 6-pyruvoyl tetrahydropterin synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.479.10 Alpha Beta 2-Layer Sandwich Tetrahydropterin Synthase; Chain A Tetrahydropterin Synthase; Chain A 3qnaA00
1B66A 1GTQA 3QNAA 4NTNA 3D7JA 3JYGA 3I2BA 3LX3A 4NTMA 2DJ6A 3LZEA 1B6ZA 3QN0A 3QN9A 2G64A 2A0SA 1Y13A 3M0NA 4NTKA 2DTTA 2OBAA
chains in the Genus database with same CATH superfamily
1B66A 1GTQA 3BK6A 1AIPC 3QNAA 4NTNA 4FVFA 3D7JA 3JYGA 3I2BA 1XB2B 3LX3A 4FVGA 4NTMA 2DJ6A 3LZEA 1B6ZA 1TFEA 3QN0A 1WINA 2RPBA 1EFUB 2G64A 2A0SA 3QN9A 4Q7JA 1Y13A 3M0NA 4NTKA 4FVJA 2DTTA 2OBAA
chains in the Genus database with same CATH topology
1B66A 1GTQA 3BK6A 3QNAA 4NTNA 4FVFA 3D7JA 3JYGA 3I2BA 3LX3A 4FVGA 4NTMA 2DJ6A 3LZEA 1B6ZA 3QN0A 1WINA 2RPBA 2G64A 2A0SA 3QN9A 1Y13A 3M0NA 4NTKA 4FVJA 2DTTA 2OBAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1B66 A;  1GTQ A;  3QNA A;  4NTN A;  3D7J A;  3JYG A;  3I2B A;  3LX3 A;  4NTM A;  2DJ6 A;  3LZE A;  1B6Z A;  3QN0 A;  3QN9 A;  2G64 A;  2A0S A;  1Y13 A;  3M0N A;  4NTK A;  2DTT A;  2OBA A; 
#chains in the Genus database with same CATH topology
 1B66 A;  1GTQ A;  3BK6 A;  1AIP C;  3QNA A;  4NTN A;  4FVF A;  3D7J A;  3JYG A;  3I2B A;  1XB2 B;  3LX3 A;  4FVG A;  4NTM A;  2DJ6 A;  3LZE A;  1B6Z A;  1TFE A;  3QN0 A;  1WIN A;  2RPB A;  1EFU B;  2G64 A;  2A0S A;  3QN9 A;  4Q7J A;  1Y13 A;  3M0N A;  4NTK A;  4FVJ A;  2DTT A;  2OBA A; 
#chains in the Genus database with same CATH homology
 1B66 A;  1GTQ A;  3BK6 A;  3QNA A;  4NTN A;  4FVF A;  3D7J A;  3JYG A;  3I2B A;  3LX3 A;  4FVG A;  4NTM A;  2DJ6 A;  3LZE A;  1B6Z A;  3QN0 A;  1WIN A;  2RPB A;  2G64 A;  2A0S A;  3QN9 A;  1Y13 A;  3M0N A;  4NTK A;  4FVJ A;  2DTT A;  2OBA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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