3RBBA

Hiv-1 nef protein in complex with engineered hck sh3 domain
Total Genus 34
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
137
structure length
137
Chain Sequence
FPVRPQVPLRPMTYKAALDISHFLKEKGGLEGLIWSQRRQEILDLWIYHTQGYFPDWQNYTPGPGIRYPLTFGWCFKLVPVEPEKVEEANEGENNSLLHPMSLHGMEDAEKEVLVWRFDSKLAFHHMARELHPEYYK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformation of the Dileucine-Based Sorting Motif in HIV-1 Nef Revealed by Intermolecular Domain Assembly.
pubmed doi rcsb
molecule tags Viral protein, protein binding
source organism Hiv-1 m:b_arv2/sf2
molecule keywords Protein Nef
total genus 34
structure length 137
sequence length 137
chains with identical sequence C
ec nomenclature
pdb deposition date 2011-03-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.62.10 Alpha Beta 2-Layer Sandwich Nef Regulatory Factor Nef Regulatory Factor 3rbbA00
1EFNB 4D8DB 2XI1A 2NEFA 1AVZA 1AVVA 2XI1B 3REAA 3RBBA 4EMZB 3IOZA 3REBA 4EN2B 4ORZB 4NEEC 4U5WA 3IK5A
chains in the Genus database with same CATH superfamily
1EFNB 4D8DB 2XI1A 2NEFA 1AVZA 1AVVA 2XI1B 3REAA 3RBBA 4EMZB 3IOZA 3REBA 4EN2B 4ORZB 4NEEC 4U5WA 3IK5A
chains in the Genus database with same CATH topology
1EFNB 4D8DB 2XI1A 2NEFA 1AVZA 1AVVA 2XI1B 3REAA 3RBBA 4EMZB 3IOZA 3REBA 4EN2B 4ORZB 4NEEC 4U5WA 3IK5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EFN B;  4D8D B;  2XI1 A;  2NEF A;  1AVZ A;  1AVV A;  2XI1 B;  3REA A;  3RBB A;  4EMZ B;  3IOZ A;  3REB A;  4EN2 B;  4ORZ B;  4NEE C;  4U5W A;  3IK5 A; 
#chains in the Genus database with same CATH topology
 1EFN B;  4D8D B;  2XI1 A;  2NEF A;  1AVZ A;  1AVV A;  2XI1 B;  3REA A;  3RBB A;  4EMZ B;  3IOZ A;  3REB A;  4EN2 B;  4ORZ B;  4NEE C;  4U5W A;  3IK5 A; 
#chains in the Genus database with same CATH homology
 1EFN B;  4D8D B;  2XI1 A;  2NEF A;  1AVZ A;  1AVV A;  2XI1 B;  3REA A;  3RBB A;  4EMZ B;  3IOZ A;  3REB A;  4EN2 B;  4ORZ B;  4NEE C;  4U5W A;  3IK5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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