4FZ2A

Crystal structure of the fourth type of archaeal trna splicing endonuclease from candidatus micrarchaeum acidiphilum arman-2
Total Genus 125
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
125
sequence length
386
structure length
386
Chain Sequence
TLLLNINTKAKRISVSDQSTIDILRNGYFGEYRAGKLMLEVEEGLYLVDVRKAACTDENSKPVSFNDIAGVFIKRKKLMARYFTFKDWRDRGLIIKSPGLRFGEEEHVQAKRYPSSAINLKKYSVTGIFFPDDMVTVIDDDESGKDLYENFWLGQYGTYKVSEHGNLNKLDIYETLFLIDMGVISIKNFTRAQIVNIASARRTDIMKLYDVYKDWRTKGYVVKTGFKFGTNFRIYFPGAKPIKENNEWIHSKHVLHVFPRDSKLIISEWARAIRVAHSVRKTFILAIPGKTRKKKLAIDFELYHRRGGDIEIPGKNSPRFGMLSLSENERIGGSELSAIINEAKSRKLELVIAIADSETSVTYYKVRRVDLPKSEYEYYEIDWMQP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray structure of the fourth type of archaeal tRNA splicing endonuclease: insights into the evolution of a novel three-unit composition and a unique loop involved in broad substrate specificity
pubmed doi rcsb
molecule tags Hydrolase
source organism Candidatus micrarchaeum acidiphilum
molecule keywords tRNA intron endonuclease
total genus 125
structure length 386
sequence length 386
chains with identical sequence B
ec nomenclature ec 3.1.27.9: Transferred entry: 4.6.1.16.
pdb deposition date 2012-07-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01974 tRNA_int_endo tRNA intron endonuclease, catalytic C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1170.20 Alpha Beta 3-Layer(aba) Sandwich MutS, DNA mismatch repair protein, domain I tRNA intron endonuclease, N-terminal domain 4fz2A01
2ZYZB 1RLVA 3AJVA 1A79A 3AJVB 2CV8A 3IEYA 3P1ZA 1R11A 3P1ZB 4FZ2A 3P1YA 2GJWA 1R0VA
chains in the Genus database with same CATH superfamily
1NNEA 3THWA 3ZLJA 2O8EB 3AJVB 2O8FB 2FWRA 2O8DB 3P1ZA 2O8CA 3THYA 2GJWA 1E3MA 1WBBA 2ZYZB 3THXB 2FZ4A 3THWB 2CV8A 3K0SA 1WB9A 3P1ZB 3P1YA 3THYB 2WTUA 2O8CB 1R0VA 1OH7A 1RLVA 1OH6A 1OH8A 2O8BA 1W7AA 3IEYA 1WBDA 1EWQA 1R11A 4FZ2A 1FW6A 1OH5A 2O8EA 3AJVA 1NG9A 2O8FA 1A79A 2O8DA 2O8BB 3THXA
chains in the Genus database with same CATH topology
2ZYZB 1RLVA 3AJVA 1A79A 3AJVB 2CV8A 3IEYA 3P1ZA 1R11A 3P1ZB 4FZ2A 3P1YA 2GJWA 1R0VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZYZ B;  1RLV A;  3AJV A;  1A79 A;  3AJV B;  2CV8 A;  3IEY A;  3P1Z A;  1R11 A;  3P1Z B;  4FZ2 A;  3P1Y A;  2GJW A;  1R0V A; 
#chains in the Genus database with same CATH topology
 1NNE A;  3THW A;  3ZLJ A;  2O8E B;  3AJV B;  2O8F B;  2FWR A;  2O8D B;  3P1Z A;  2O8C A;  3THY A;  2GJW A;  1E3M A;  1WBB A;  2ZYZ B;  3THX B;  2FZ4 A;  3THW B;  2CV8 A;  3K0S A;  1WB9 A;  3P1Z B;  3P1Y A;  3THY B;  2WTU A;  2O8C B;  1R0V A;  1OH7 A;  1RLV A;  1OH6 A;  1OH8 A;  2O8B A;  1W7A A;  3IEY A;  1WBD A;  1EWQ A;  1R11 A;  4FZ2 A;  1FW6 A;  1OH5 A;  2O8E A;  3AJV A;  1NG9 A;  2O8F A;  1A79 A;  2O8D A;  2O8B B;  3THX A; 
#chains in the Genus database with same CATH homology
 2ZYZ B;  1RLV A;  3AJV A;  1A79 A;  3AJV B;  2CV8 A;  3IEY A;  3P1Z A;  1R11 A;  3P1Z B;  4FZ2 A;  3P1Y A;  2GJW A;  1R0V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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