4FZ2A

Crystal structure of the fourth type of archaeal trna splicing endonuclease from candidatus micrarchaeum acidiphilum arman-2
Total Genus 125
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
125
sequence length
386
structure length
386
Chain Sequence
TLLLNINTKAKRISVSDQSTIDILRNGYFGEYRAGKLMLEVEEGLYLVDVRKAACTDENSKPVSFNDIAGVFIKRKKLMARYFTFKDWRDRGLIIKSPGLRFGEEEHVQAKRYPSSAINLKKYSVTGIFFPDDMVTVIDDDESGKDLYENFWLGQYGTYKVSEHGNLNKLDIYETLFLIDMGVISIKNFTRAQIVNIASARRTDIMKLYDVYKDWRTKGYVVKTGFKFGTNFRIYFPGAKPIKENNEWIHSKHVLHVFPRDSKLIISEWARAIRVAHSVRKTFILAIPGKTRKKKLAIDFELYHRRGGDIEIPGKNSPRFGMLSLSENERIGGSELSAIINEAKSRKLELVIAIADSETSVTYYKVRRVDLPKSEYEYYEIDWMQP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray structure of the fourth type of archaeal tRNA splicing endonuclease: insights into the evolution of a novel three-unit composition and a unique loop involved in broad substrate specificity
pubmed doi rcsb
molecule keywords tRNA intron endonuclease
molecule tags Hydrolase
source organism Candidatus micrarchaeum acidiphilum
total genus 125
structure length 386
sequence length 386
chains with identical sequence B
ec nomenclature ec 3.1.27.9: Transferred entry: 4.6.1.16.
pdb deposition date 2012-07-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01974 tRNA_int_endo tRNA intron endonuclease, catalytic C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1170.20 Alpha Beta 3-Layer(aba) Sandwich MutS, DNA mismatch repair protein, domain I tRNA intron endonuclease, N-terminal domain 4fz2A01
1R0VA 1R11A 3AJVB 2CV8A 3P1YA 1A79A 2ZYZB 3IEYA 3P1ZA 4FZ2A 2GJWA 1RLVA 3AJVA 3P1ZB
chains in the Genus database with same CATH superfamily
1OH8A 1R0VA 1OH6A 2CV8A 2ZYZB 2FZ4A 2GJWA 1OH5A 1RLVA 1E3MA 2O8FB 3THYB 3THWB 1WBDA 1OH7A 3P1YA 3ZLJA 2O8CB 1A79A 3IEYA 3THYA 3THWA 2O8FA 1WBBA 1NNEA 3P1ZB 3K0SA 1NG9A 2O8CA 1EWQA 2O8EB 3AJVB 1R11A 2O8DB 3THXB 1WB9A 3P1ZA 2O8EA 3AJVA 2WTUA 2O8DA 3THXA 2FWRA 2O8BB 4FZ2A 1FW6A 1W7AA 2O8BA
chains in the Genus database with same CATH topology
1R0VA 1R11A 3AJVB 2CV8A 3P1YA 1A79A 2ZYZB 3IEYA 3P1ZA 4FZ2A 2GJWA 1RLVA 3AJVA 3P1ZB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1R0V A;  1R11 A;  3AJV B;  2CV8 A;  3P1Y A;  1A79 A;  2ZYZ B;  3IEY A;  3P1Z A;  4FZ2 A;  2GJW A;  1RLV A;  3AJV A;  3P1Z B; 
#chains in the Genus database with same CATH topology
 1OH8 A;  1R0V A;  1OH6 A;  2CV8 A;  2ZYZ B;  2FZ4 A;  2GJW A;  1OH5 A;  1RLV A;  1E3M A;  2O8F B;  3THY B;  3THW B;  1WBD A;  1OH7 A;  3P1Y A;  3ZLJ A;  2O8C B;  1A79 A;  3IEY A;  3THY A;  3THW A;  2O8F A;  1WBB A;  1NNE A;  3P1Z B;  3K0S A;  1NG9 A;  2O8C A;  1EWQ A;  2O8E B;  3AJV B;  1R11 A;  2O8D B;  3THX B;  1WB9 A;  3P1Z A;  2O8E A;  3AJV A;  2WTU A;  2O8D A;  3THX A;  2FWR A;  2O8B B;  4FZ2 A;  1FW6 A;  1W7A A;  2O8B A; 
#chains in the Genus database with same CATH homology
 1R0V A;  1R11 A;  3AJV B;  2CV8 A;  3P1Y A;  1A79 A;  2ZYZ B;  3IEY A;  3P1Z A;  4FZ2 A;  2GJW A;  1RLV A;  3AJV A;  3P1Z B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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