4FZ2A

Crystal structure of the fourth type of archaeal trna splicing endonuclease from candidatus micrarchaeum acidiphilum arman-2
Total Genus 125
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
125
sequence length
386
structure length
386
Chain Sequence
TLLLNINTKAKRISVSDQSTIDILRNGYFGEYRAGKLMLEVEEGLYLVDVRKAACTDENSKPVSFNDIAGVFIKRKKLMARYFTFKDWRDRGLIIKSPGLRFGEEEHVQAKRYPSSAINLKKYSVTGIFFPDDMVTVIDDDESGKDLYENFWLGQYGTYKVSEHGNLNKLDIYETLFLIDMGVISIKNFTRAQIVNIASARRTDIMKLYDVYKDWRTKGYVVKTGFKFGTNFRIYFPGAKPIKENNEWIHSKHVLHVFPRDSKLIISEWARAIRVAHSVRKTFILAIPGKTRKKKLAIDFELYHRRGGDIEIPGKNSPRFGMLSLSENERIGGSELSAIINEAKSRKLELVIAIADSETSVTYYKVRRVDLPKSEYEYYEIDWMQP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray structure of the fourth type of archaeal tRNA splicing endonuclease: insights into the evolution of a novel three-unit composition and a unique loop involved in broad substrate specificity
pubmed doi rcsb
molecule keywords tRNA intron endonuclease
molecule tags Hydrolase
source organism Candidatus micrarchaeum acidiphilum
total genus 125
structure length 386
sequence length 386
chains with identical sequence B
ec nomenclature ec 3.1.27.9: Transferred entry: 4.6.1.16.
pdb deposition date 2012-07-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01974 tRNA_int_endo tRNA intron endonuclease, catalytic C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1170.20 Alpha Beta 3-Layer(aba) Sandwich MutS, DNA mismatch repair protein, domain I tRNA intron endonuclease, N-terminal domain 4fz2A01
4FZ2A 1RLVA 1R0VA 3IEYA 3P1YA 1R11A 3P1ZB 3AJVB 2CV8A 3P1ZA 3AJVA 2GJWA 2ZYZB 1A79A
chains in the Genus database with same CATH superfamily
2WTUA 1WBDA 2O8CB 1EWQA 2O8BB 2O8DA 1R11A 1NG9A 3THXA 3AJVA 3THYA 2GJWA 3K0SA 1A79A 1FW6A 1E3MA 2O8EB 2FZ4A 2O8FA 3P1ZB 2CV8A 1OH8A 3THWA 3THXB 1NNEA 4FZ2A 2O8DB 1WBBA 1OH7A 2O8CA 2O8BA 3AJVB 3ZLJA 3THYB 2ZYZB 1W7AA 1OH5A 1RLVA 2O8EA 1R0VA 3P1YA 2O8FB 3THWB 1OH6A 1WB9A 3P1ZA 2FWRA 3IEYA
chains in the Genus database with same CATH topology
4FZ2A 1RLVA 1R0VA 3IEYA 3P1YA 1R11A 3P1ZB 3AJVB 2CV8A 3P1ZA 3AJVA 2GJWA 2ZYZB 1A79A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FZ2 A;  1RLV A;  1R0V A;  3IEY A;  3P1Y A;  1R11 A;  3P1Z B;  3AJV B;  2CV8 A;  3P1Z A;  3AJV A;  2GJW A;  2ZYZ B;  1A79 A; 
#chains in the Genus database with same CATH topology
 2WTU A;  1WBD A;  2O8C B;  1EWQ A;  2O8B B;  2O8D A;  1R11 A;  1NG9 A;  3THX A;  3AJV A;  3THY A;  2GJW A;  3K0S A;  1A79 A;  1FW6 A;  1E3M A;  2O8E B;  2FZ4 A;  2O8F A;  3P1Z B;  2CV8 A;  1OH8 A;  3THW A;  3THX B;  1NNE A;  4FZ2 A;  2O8D B;  1WBB A;  1OH7 A;  2O8C A;  2O8B A;  3AJV B;  3ZLJ A;  3THY B;  2ZYZ B;  1W7A A;  1OH5 A;  1RLV A;  2O8E A;  1R0V A;  3P1Y A;  2O8F B;  3THW B;  1OH6 A;  1WB9 A;  3P1Z A;  2FWR A;  3IEY A; 
#chains in the Genus database with same CATH homology
 4FZ2 A;  1RLV A;  1R0V A;  3IEY A;  3P1Y A;  1R11 A;  3P1Z B;  3AJV B;  2CV8 A;  3P1Z A;  3AJV A;  2GJW A;  2ZYZ B;  1A79 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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