4IHDA

Crystal structure of uncleaved thnt t282c, derivatized at the active site with ethg
Total Genus 116
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
116
sequence length
374
structure length
361
Chain Sequence
GIGGVPGPHNGLTDVPGVRVGHAGRTGDGWLTGVTVVLAPPGGAVAAVDVRGGGPGTRETDALDPRNLVQTIDAVVLTGGSAFGLDAAGGVAAWLEEQGRGFPVGADPSQVVPVVPAAALFDLGRGGTWRARPDAALGRAAVEAAAARPEGDPVEQGGVGAGTGAVVGGLKGGIGTASVVLDSGATVAALAAVNAAGSAVDPATGVLYGARTGLPGEFAGYGVPDAIGADTHARARARLAEAAEETARRRAGGAATLNCTLAVVATDATLTRAQAQKLAGTAHDGLARAVRPVHLLSDGDTVFALSTGRRPLLPHLEAGALNEVLAAGADVLTRAVVHAVLAATGVDTPGGVHPSYRELYA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Exploring the Role of Conformational Heterogeneity in cis-Autoproteolytic Activation of ThnT.
pubmed doi rcsb
molecule tags Hydrolase
source organism Streptomyces cattleya
molecule keywords ThnT protein
total genus 116
structure length 361
sequence length 374
chains with identical sequence B
ec nomenclature ec 3.5.1.92: Pantetheine hydrolase.
pdb deposition date 2012-12-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03576 Peptidase_S58 Peptidase family S58
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.70.12 Alpha Beta 4-Layer Sandwich L-amino peptidase D-ALA esterase/amidase L-amino peptidase D-ALA esterase/amidase 4ihdA00
3AXGA 2DRHA 4IHDA 1VZ7A 3NFBA 1B65A 3N5IA 3N2WA 2YEPA 3IT6A 1VZ8A 4IHEA 3IT4A 2V4IA 3TM2A 2VZKA 1VZ6A 3N33A 1VRAA 3TM1A 3NDVA 3S3UA
chains in the Genus database with same CATH superfamily
3AXGA 2DRHA 4IHDA 1VZ7A 3NFBA 1B65A 3N5IA 3N2WA 2YEPA 3IT6A 1VZ8A 4IHEA 3IT4A 2V4IA 3TM2A 2VZKA 1VZ6A 3N33A 1VRAA 3TM1A 3NDVA 3S3UA
chains in the Genus database with same CATH topology
3AXGA 2DRHA 4IHDA 1VZ7A 3NFBA 1B65A 3N5IA 3N2WA 2YEPA 3IT6A 1VZ8A 4IHEA 3IT4A 2V4IA 3TM2A 2VZKA 1VZ6A 3N33A 1VRAA 3TM1A 3NDVA 3S3UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AXG A;  2DRH A;  4IHD A;  1VZ7 A;  3NFB A;  1B65 A;  3N5I A;  3N2W A;  2YEP A;  3IT6 A;  1VZ8 A;  4IHE A;  3IT4 A;  2V4I A;  3TM2 A;  2VZK A;  1VZ6 A;  3N33 A;  1VRA A;  3TM1 A;  3NDV A;  3S3U A; 
#chains in the Genus database with same CATH topology
 3AXG A;  2DRH A;  4IHD A;  1VZ7 A;  3NFB A;  1B65 A;  3N5I A;  3N2W A;  2YEP A;  3IT6 A;  1VZ8 A;  4IHE A;  3IT4 A;  2V4I A;  3TM2 A;  2VZK A;  1VZ6 A;  3N33 A;  1VRA A;  3TM1 A;  3NDV A;  3S3U A; 
#chains in the Genus database with same CATH homology
 3AXG A;  2DRH A;  4IHD A;  1VZ7 A;  3NFB A;  1B65 A;  3N5I A;  3N2W A;  2YEP A;  3IT6 A;  1VZ8 A;  4IHE A;  3IT4 A;  2V4I A;  3TM2 A;  2VZK A;  1VZ6 A;  3N33 A;  1VRA A;  3TM1 A;  3NDV A;  3S3U A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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