4NTKA

Qued from e. coli
Total Genus 31
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
31
sequence length
121
structure length
121
Chain Sequence
MMSTTLFKDFTFEAAHRLPHVPEGHKAGRLHGHSFMVRLEITGEVDPHTGWIIDFAELKAAFKPTYERLDHHYLNDIPGLENPTSEVLAKWIWDQVKPVVPLLSAVMVKETCTAGCIYRGE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Biochemical and Structural Studies of 6-Carboxy-5,6,7,8-tetrahydropterin Synthase Reveal the Molecular Basis of Catalytic Promiscuity within the Tunnel-fold Superfamily.
pubmed doi rcsb
molecule tags Lyase
source organism Escherichia coli
molecule keywords 6-carboxy-5,6,7,8-tetrahydropterin synthase
total genus 31
structure length 121
sequence length 121
chains with identical sequence B, C, D, E, F
ec nomenclature ec 4.1.2.50: 6-carboxytetrahydropterin synthase.
pdb deposition date 2013-12-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01242 PTPS 6-pyruvoyl tetrahydropterin synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.479.10 Alpha Beta 2-Layer Sandwich Tetrahydropterin Synthase; Chain A Tetrahydropterin Synthase; Chain A 4ntkA00
2DJ6A 2DTTA 4NTNA 3LZEA 3I2BA 3QN0A 2G64A 4NTMA 3QNAA 1GTQA 4NTKA 3M0NA 2A0SA 3D7JA 3QN9A 3LX3A 1B66A 2OBAA 3JYGA 1Y13A 1B6ZA
chains in the Genus database with same CATH superfamily
2DJ6A 2DTTA 4NTNA 1TFEA 1WINA 3LZEA 3I2BA 3QN0A 2G64A 4NTMA 3QNAA 1GTQA 4NTKA 4FVJA 3M0NA 2A0SA 3D7JA 3QN9A 1B66A 3LX3A 1EFUB 1XB2B 2OBAA 3JYGA 4FVGA 1Y13A 4Q7JA 4FVFA 3BK6A 2RPBA 1B6ZA 1AIPC
chains in the Genus database with same CATH topology
2DJ6A 2DTTA 4NTNA 1WINA 3LZEA 3I2BA 3QN0A 2G64A 4NTMA 3QNAA 1GTQA 4NTKA 4FVJA 3M0NA 2A0SA 3D7JA 3QN9A 3LX3A 1B66A 2OBAA 3JYGA 4FVGA 1Y13A 4FVFA 3BK6A 2RPBA 1B6ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DJ6 A;  2DTT A;  4NTN A;  3LZE A;  3I2B A;  3QN0 A;  2G64 A;  4NTM A;  3QNA A;  1GTQ A;  4NTK A;  3M0N A;  2A0S A;  3D7J A;  3QN9 A;  3LX3 A;  1B66 A;  2OBA A;  3JYG A;  1Y13 A;  1B6Z A; 
#chains in the Genus database with same CATH topology
 2DJ6 A;  2DTT A;  4NTN A;  1TFE A;  1WIN A;  3LZE A;  3I2B A;  3QN0 A;  2G64 A;  4NTM A;  3QNA A;  1GTQ A;  4NTK A;  4FVJ A;  3M0N A;  2A0S A;  3D7J A;  3QN9 A;  1B66 A;  3LX3 A;  1EFU B;  1XB2 B;  2OBA A;  3JYG A;  4FVG A;  1Y13 A;  4Q7J A;  4FVF A;  3BK6 A;  2RPB A;  1B6Z A;  1AIP C; 
#chains in the Genus database with same CATH homology
 2DJ6 A;  2DTT A;  4NTN A;  1WIN A;  3LZE A;  3I2B A;  3QN0 A;  2G64 A;  4NTM A;  3QNA A;  1GTQ A;  4NTK A;  4FVJ A;  3M0N A;  2A0S A;  3D7J A;  3QN9 A;  3LX3 A;  1B66 A;  2OBA A;  3JYG A;  4FVG A;  1Y13 A;  4FVF A;  3BK6 A;  2RPB A;  1B6Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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