4NTMA

Qued soaked with sepiapterin (selenomethionine substituted protein)
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
120
structure length
114
Chain Sequence
MMSTTLFKDFTFEAAHRLPHCGRLHGHSFMVRLEITGEVDPHTGWIIDFAELKAAFKPTYERLDHHYLNDIPGLENPTSEVLAKWIWDQVKPVVPLLSAVMVKETCTAGCIYRG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Biochemical and Structural Studies of 6-Carboxy-5,6,7,8-tetrahydropterin Synthase Reveal the Molecular Basis of Catalytic Promiscuity within the Tunnel-fold Superfamily.
pubmed doi rcsb
molecule tags Lyase
source organism Escherichia coli
molecule keywords 6-carboxy-5,6,7,8-tetrahydropterin synthase
total genus 24
structure length 114
sequence length 120
chains with identical sequence B, C, D, E, F
ec nomenclature ec 4.1.2.50: 6-carboxytetrahydropterin synthase.
pdb deposition date 2013-12-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01242 PTPS 6-pyruvoyl tetrahydropterin synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.479.10 Alpha Beta 2-Layer Sandwich Tetrahydropterin Synthase; Chain A Tetrahydropterin Synthase; Chain A 4ntmA00
2DJ6A 3QN9A 1GTQA 2G64A 2DTTA 2A0SA 4NTKA 1Y13A 3D7JA 3LX3A 1B66A 3JYGA 2OBAA 3I2BA 1B6ZA 3LZEA 4NTNA 4NTMA 3QNAA 3QN0A 3M0NA
chains in the Genus database with same CATH superfamily
4FVGA 3BK6A 4Q7JA 2DJ6A 3QN9A 1GTQA 2G64A 2DTTA 2A0SA 4NTKA 1EFUB 1AIPC 2RPBA 1Y13A 3D7JA 3LX3A 4FVFA 1B66A 1XB2B 4FVJA 3JYGA 2OBAA 1TFEA 1WINA 3I2BA 1B6ZA 3LZEA 4NTNA 4NTMA 3QNAA 3QN0A 3M0NA
chains in the Genus database with same CATH topology
4FVGA 3BK6A 2DJ6A 3QN9A 1GTQA 2G64A 2DTTA 2A0SA 4NTKA 2RPBA 1Y13A 3D7JA 3LX3A 4FVFA 1B66A 4FVJA 3JYGA 2OBAA 1WINA 3I2BA 1B6ZA 3LZEA 4NTNA 4NTMA 3QNAA 3QN0A 3M0NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DJ6 A;  3QN9 A;  1GTQ A;  2G64 A;  2DTT A;  2A0S A;  4NTK A;  1Y13 A;  3D7J A;  3LX3 A;  1B66 A;  3JYG A;  2OBA A;  3I2B A;  1B6Z A;  3LZE A;  4NTN A;  4NTM A;  3QNA A;  3QN0 A;  3M0N A; 
#chains in the Genus database with same CATH topology
 4FVG A;  3BK6 A;  4Q7J A;  2DJ6 A;  3QN9 A;  1GTQ A;  2G64 A;  2DTT A;  2A0S A;  4NTK A;  1EFU B;  1AIP C;  2RPB A;  1Y13 A;  3D7J A;  3LX3 A;  4FVF A;  1B66 A;  1XB2 B;  4FVJ A;  3JYG A;  2OBA A;  1TFE A;  1WIN A;  3I2B A;  1B6Z A;  3LZE A;  4NTN A;  4NTM A;  3QNA A;  3QN0 A;  3M0N A; 
#chains in the Genus database with same CATH homology
 4FVG A;  3BK6 A;  2DJ6 A;  3QN9 A;  1GTQ A;  2G64 A;  2DTT A;  2A0S A;  4NTK A;  2RPB A;  1Y13 A;  3D7J A;  3LX3 A;  4FVF A;  1B66 A;  4FVJ A;  3JYG A;  2OBA A;  1WIN A;  3I2B A;  1B6Z A;  3LZE A;  4NTN A;  4NTM A;  3QNA A;  3QN0 A;  3M0N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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