4NTMA

Qued soaked with sepiapterin (selenomethionine substituted protein)
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
120
structure length
114
Chain Sequence
MMSTTLFKDFTFEAAHRLPHCGRLHGHSFMVRLEITGEVDPHTGWIIDFAELKAAFKPTYERLDHHYLNDIPGLENPTSEVLAKWIWDQVKPVVPLLSAVMVKETCTAGCIYRG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Biochemical and Structural Studies of 6-Carboxy-5,6,7,8-tetrahydropterin Synthase Reveal the Molecular Basis of Catalytic Promiscuity within the Tunnel-fold Superfamily.
pubmed doi rcsb
molecule keywords 6-carboxy-5,6,7,8-tetrahydropterin synthase
molecule tags Lyase
source organism Escherichia coli
total genus 24
structure length 114
sequence length 120
chains with identical sequence B, C, D, E, F
ec nomenclature ec 4.1.2.50: 6-carboxytetrahydropterin synthase.
pdb deposition date 2013-12-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01242 PTPS 6-pyruvoyl tetrahydropterin synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.479.10 Alpha Beta 2-Layer Sandwich Tetrahydropterin Synthase; Chain A Tetrahydropterin Synthase; Chain A 4ntmA00
3D7JA 4NTMA 1B66A 4NTNA 3QN0A 2G64A 3LX3A 3M0NA 2DTTA 3I2BA 3JYGA 1B6ZA 2A0SA 3QN9A 2DJ6A 1GTQA 4NTKA 3LZEA 1Y13A 3QNAA 2OBAA
chains in the Genus database with same CATH superfamily
3D7JA 4NTMA 1B66A 1XB2B 4NTNA 3QN0A 4FVGA 2RPBA 2G64A 3LX3A 4Q7JA 1TFEA 3M0NA 2DTTA 3I2BA 3JYGA 1AIPC 1EFUB 4FVJA 1B6ZA 2A0SA 1WINA 3QN9A 2DJ6A 1GTQA 4NTKA 3BK6A 3LZEA 4FVFA 1Y13A 3QNAA 2OBAA
chains in the Genus database with same CATH topology
3D7JA 4NTMA 1B66A 4NTNA 3QN0A 4FVGA 2RPBA 2G64A 3LX3A 3M0NA 2DTTA 3I2BA 3JYGA 4FVJA 1B6ZA 2A0SA 1WINA 3QN9A 2DJ6A 1GTQA 4NTKA 3BK6A 3LZEA 4FVFA 1Y13A 3QNAA 2OBAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3D7J A;  4NTM A;  1B66 A;  4NTN A;  3QN0 A;  2G64 A;  3LX3 A;  3M0N A;  2DTT A;  3I2B A;  3JYG A;  1B6Z A;  2A0S A;  3QN9 A;  2DJ6 A;  1GTQ A;  4NTK A;  3LZE A;  1Y13 A;  3QNA A;  2OBA A; 
#chains in the Genus database with same CATH topology
 3D7J A;  4NTM A;  1B66 A;  1XB2 B;  4NTN A;  3QN0 A;  4FVG A;  2RPB A;  2G64 A;  3LX3 A;  4Q7J A;  1TFE A;  3M0N A;  2DTT A;  3I2B A;  3JYG A;  1AIP C;  1EFU B;  4FVJ A;  1B6Z A;  2A0S A;  1WIN A;  3QN9 A;  2DJ6 A;  1GTQ A;  4NTK A;  3BK6 A;  3LZE A;  4FVF A;  1Y13 A;  3QNA A;  2OBA A; 
#chains in the Genus database with same CATH homology
 3D7J A;  4NTM A;  1B66 A;  4NTN A;  3QN0 A;  4FVG A;  2RPB A;  2G64 A;  3LX3 A;  3M0N A;  2DTT A;  3I2B A;  3JYG A;  4FVJ A;  1B6Z A;  2A0S A;  1WIN A;  3QN9 A;  2DJ6 A;  1GTQ A;  4NTK A;  3BK6 A;  3LZE A;  4FVF A;  1Y13 A;  3QNA A;  2OBA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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