4NTMA

Qued soaked with sepiapterin (selenomethionine substituted protein)
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
120
structure length
114
Chain Sequence
MMSTTLFKDFTFEAAHRLPHCGRLHGHSFMVRLEITGEVDPHTGWIIDFAELKAAFKPTYERLDHHYLNDIPGLENPTSEVLAKWIWDQVKPVVPLLSAVMVKETCTAGCIYRG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Biochemical and Structural Studies of 6-Carboxy-5,6,7,8-tetrahydropterin Synthase Reveal the Molecular Basis of Catalytic Promiscuity within the Tunnel-fold Superfamily.
pubmed doi rcsb
molecule tags Lyase
source organism Escherichia coli
molecule keywords 6-carboxy-5,6,7,8-tetrahydropterin synthase
total genus 24
structure length 114
sequence length 120
chains with identical sequence B, C, D, E, F
ec nomenclature ec 4.1.2.50: 6-carboxytetrahydropterin synthase.
pdb deposition date 2013-12-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01242 PTPS 6-pyruvoyl tetrahydropterin synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.479.10 Alpha Beta 2-Layer Sandwich Tetrahydropterin Synthase; Chain A Tetrahydropterin Synthase; Chain A 4ntmA00
2OBAA 3LX3A 2G64A 3I2BA 3D7JA 3JYGA 2DJ6A 1Y13A 1B66A 3QNAA 1GTQA 4NTNA 4NTKA 3M0NA 3QN0A 2DTTA 4NTMA 2A0SA 3QN9A 1B6ZA 3LZEA
chains in the Genus database with same CATH superfamily
2OBAA 3LX3A 2G64A 1EFUB 3I2BA 3D7JA 3JYGA 4Q7JA 2DJ6A 1Y13A 3BK6A 4FVJA 4FVGA 1TFEA 1B66A 1XB2B 3QNAA 1GTQA 4NTNA 4NTKA 3M0NA 3QN0A 2DTTA 2RPBA 4NTMA 1WINA 2A0SA 3QN9A 4FVFA 1B6ZA 3LZEA 1AIPC
chains in the Genus database with same CATH topology
2OBAA 3LX3A 2G64A 3I2BA 3D7JA 3JYGA 2DJ6A 1Y13A 3BK6A 4FVJA 4FVGA 1B66A 3QNAA 1GTQA 4NTNA 4NTKA 3M0NA 3QN0A 2DTTA 2RPBA 4NTMA 1WINA 2A0SA 3QN9A 4FVFA 1B6ZA 3LZEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OBA A;  3LX3 A;  2G64 A;  3I2B A;  3D7J A;  3JYG A;  2DJ6 A;  1Y13 A;  1B66 A;  3QNA A;  1GTQ A;  4NTN A;  4NTK A;  3M0N A;  3QN0 A;  2DTT A;  4NTM A;  2A0S A;  3QN9 A;  1B6Z A;  3LZE A; 
#chains in the Genus database with same CATH topology
 2OBA A;  3LX3 A;  2G64 A;  1EFU B;  3I2B A;  3D7J A;  3JYG A;  4Q7J A;  2DJ6 A;  1Y13 A;  3BK6 A;  4FVJ A;  4FVG A;  1TFE A;  1B66 A;  1XB2 B;  3QNA A;  1GTQ A;  4NTN A;  4NTK A;  3M0N A;  3QN0 A;  2DTT A;  2RPB A;  4NTM A;  1WIN A;  2A0S A;  3QN9 A;  4FVF A;  1B6Z A;  3LZE A;  1AIP C; 
#chains in the Genus database with same CATH homology
 2OBA A;  3LX3 A;  2G64 A;  3I2B A;  3D7J A;  3JYG A;  2DJ6 A;  1Y13 A;  3BK6 A;  4FVJ A;  4FVG A;  1B66 A;  3QNA A;  1GTQ A;  4NTN A;  4NTK A;  3M0N A;  3QN0 A;  2DTT A;  2RPB A;  4NTM A;  1WIN A;  2A0S A;  3QN9 A;  4FVF A;  1B6Z A;  3LZE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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