4NTNA

E.coli qued, semet protein, 2a resolution
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
118
structure length
118
Chain Sequence
STTLFKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEVDPHTGWIIDFAELKAAFKPTYERLDHHYLNDIPGLENPTSEVLAKWIWDQVKPVVPLLSAVMVKETCTAGCIYRG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Biochemical and Structural Studies of 6-Carboxy-5,6,7,8-tetrahydropterin Synthase Reveal the Molecular Basis of Catalytic Promiscuity within the Tunnel-fold Superfamily.
pubmed doi rcsb
molecule tags Lyase
source organism Escherichia coli
molecule keywords 6-carboxy-5,6,7,8-tetrahydropterin synthase
total genus 28
structure length 118
sequence length 118
chains with identical sequence B, C, D, E, F
ec nomenclature ec 4.1.2.50: 6-carboxytetrahydropterin synthase.
pdb deposition date 2013-12-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01242 PTPS 6-pyruvoyl tetrahydropterin synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.479.10 Alpha Beta 2-Layer Sandwich Tetrahydropterin Synthase; Chain A Tetrahydropterin Synthase; Chain A 4ntnA00
2DJ6A 1B66A 3QN0A 2A0SA 3M0NA 3JYGA 3D7JA 3QN9A 3QNAA 4NTKA 1GTQA 2DTTA 1Y13A 4NTNA 3LZEA 4NTMA 3LX3A 3I2BA 1B6ZA 2OBAA 2G64A
chains in the Genus database with same CATH superfamily
2DJ6A 1B66A 3QN0A 2A0SA 1AIPC 3M0NA 3JYGA 3D7JA 3QN9A 3QNAA 4FVGA 3BK6A 4FVJA 1TFEA 4NTKA 1GTQA 1EFUB 2DTTA 1Y13A 4NTNA 4FVFA 3LZEA 4Q7JA 1XB2B 4NTMA 3LX3A 1WINA 3I2BA 1B6ZA 2OBAA 2G64A 2RPBA
chains in the Genus database with same CATH topology
2DJ6A 1B66A 3QN0A 2A0SA 3M0NA 3JYGA 3D7JA 3QN9A 3QNAA 4FVGA 3BK6A 4FVJA 4NTKA 1GTQA 2DTTA 1Y13A 4NTNA 4FVFA 3LZEA 4NTMA 3LX3A 1WINA 3I2BA 1B6ZA 2OBAA 2G64A 2RPBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DJ6 A;  1B66 A;  3QN0 A;  2A0S A;  3M0N A;  3JYG A;  3D7J A;  3QN9 A;  3QNA A;  4NTK A;  1GTQ A;  2DTT A;  1Y13 A;  4NTN A;  3LZE A;  4NTM A;  3LX3 A;  3I2B A;  1B6Z A;  2OBA A;  2G64 A; 
#chains in the Genus database with same CATH topology
 2DJ6 A;  1B66 A;  3QN0 A;  2A0S A;  1AIP C;  3M0N A;  3JYG A;  3D7J A;  3QN9 A;  3QNA A;  4FVG A;  3BK6 A;  4FVJ A;  1TFE A;  4NTK A;  1GTQ A;  1EFU B;  2DTT A;  1Y13 A;  4NTN A;  4FVF A;  3LZE A;  4Q7J A;  1XB2 B;  4NTM A;  3LX3 A;  1WIN A;  3I2B A;  1B6Z A;  2OBA A;  2G64 A;  2RPB A; 
#chains in the Genus database with same CATH homology
 2DJ6 A;  1B66 A;  3QN0 A;  2A0S A;  3M0N A;  3JYG A;  3D7J A;  3QN9 A;  3QNA A;  4FVG A;  3BK6 A;  4FVJ A;  4NTK A;  1GTQ A;  2DTT A;  1Y13 A;  4NTN A;  4FVF A;  3LZE A;  4NTM A;  3LX3 A;  1WIN A;  3I2B A;  1B6Z A;  2OBA A;  2G64 A;  2RPB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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