1P9PA

The crystal structure of a m1g37 trna methyltransferase, trmd
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
Knots found
sequence length
246
structure length
235
Chain Sequence
MWIGIISLFPEMFRAITDYGVTGRAVKNGLLSIQSWSPRDFTHDRHRTVDDRPYGGGPGMLMMVQPLRDAIHAAKAAAGEGAKVIYLSPQGRKLDQAGVSELATNQKLILVCGRYEGIDERVIQTEIDEEWSIGDYVLSGGELPAMTLIDSVSRFIPGVLGEGLLDCPHYTRPEVLEGMEVPPVLLSGNHAEIRRWRLKQSLGRTWLRRPELLENLALTEEQARLLAEFKTEHAQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Insights into Catalysis by a Knotted TrmD tRNA Methyltransferase.
pubmed doi rcsb
molecule tags Transferase
source organism Escherichia coli
molecule keywords tRNA (Guanine-N(1)-)-methyltransferase
total genus 67
structure length 235
sequence length 246
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2003-05-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 1p9pA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 1p9pA01
4CNGA 4YQAA 4YQ7A 3L8UA 3ONPA 4KDZA 4E8BA 1ZJRA 3E5YA 4YQ5A 1Z85A 4YQKA 4CNEA 4MCCA 2EGVA 4YVIA 3KTYA 3AIAA 4YQJA 3OIIA 1V2XA 3KNUA 3BBEA 4H3ZA 4YQ2A 1UAJA 4YVGA 1TO0A 1VH0A 2V3KA 2Z0YA 2I6DA 3GYQA 3IC6A 4FAKA 4XBOA 3QUVA 1IPAA 2EGWA 4KGNA 4YQCA 4YQ8A 4YQSA 4MCDA 4IG6A 4YQ9A 1P9PA 3O7BA 1GZ0A 3N4JA 4MCBA 1UAMA 3BBHA 2CX8A 4J3CA 4YQ4A 4L69A 5FAIA 3BBDA 2QMMA 1K3RA 4YQ3A 4YQNA 3OIJA 3NK7A 4YQQA 4CNFA 3KW2A 1O6DA 4YQ6A 2QWVA 1NXZA 5D9FA 5GMBA 4YPZA 4YQTA 2YY8A 4YPYA 4YQRA 1V6ZA 4X3MA 4YQPA 3ILKA 4PZKA 4YPWA 4YQ0A 1VHYA 3N4KA 3IEFA 3OINA 4YQ1A 1X7PA 4YQIA 1J85A 4YQBA 4JAKA 1UAKA 4YQOA 4YQDA 1NS5A 2V3JA 4YQLA 4YVKA 2O3AA 5GM8A 4YVHA 4H3YA 2HA8A 3AXZA 4X3LA 3AI9X 4YPXA 4YVJA 4CNDA 5CO4A 3NK6A 1VHKA 1MXIA 4RG1A 1UALA 3KY7A 3DCMX 1X7OA 5GMCA 4JALA 1OY5A 4YQGA
chains in the Genus database with same CATH superfamily
1WRTR 4JWFA 4CNGA 4YQAA 4YQ7A 3L8UA 3ONPA 4KDZA 4E8BA 1ZJRA 3E5YA 4YQ5A 1Z85A 4YQKA 4CNEA 4MCCA 2EGVA 4YVIA 1MI7R 3SSXN 3KTYA 3AIAA 1RCSA 4YQJA 3OIIA 1V2XA 3KNUA 3BBEA 4H3ZA 3SSWN 4YQ2A 1JHGA 1UAJA 4YVGA 1TO0A 1VH0A 2V3KA 2Z0YA 2I6DA 3GYQA 3IC6A 4FAKA 4XBOA 3QUVA 1IPAA 2EGWA 4KGNA 4YQCA 4YQ8A 4JWJA 4YQSA 4IG6A 4MCDA 2OZ9R 1P9PA 4YQ9A 3O7BA 1GZ0A 3FRWA 4MCBA 2XDIA 3N4JA 1UAMA 3BBHA 4FMWA 2CX8A 4J3CA 4YQ4A 4L69A 5FAIA 3BBDA 2QMMA 1CO0A 1K3RA 4YQ3A 4YQNA 3OIJA 3NK7A 4YQQA 4CNFA 1TROA 3G1CA 3KW2A 1O6DA 4YQ6A 2QWVA 4JWHA 1NXZA 1TRRA 3WRPA 5D9FA 5GMBA 4YPZA 4YQTA 2YY8A 1WRSR 4YPYA 4YQRA 1V6ZA 4X3MA 4YQPA 3ILKA 4PZKA 4YPWA 4YQ0A 1VHYA 3N4KA 3IEFA 3OINA 4YQ1A 1X7PA 3KORA 4YQIA 1ZT9A 1J85A 4YQBA 4JAKA 1UAKA 4YQOA 4YQDA 1NS5A 2V3JA 4YQLA 4YVKA 2O3AA 5GM8A 4YVHA 4H3YA 2HA8A 3AXZA 4X3LA 3AI9X 4YPXA 4YVJA 4CNDA 5CO4A 3NK6A 1VHKA 1MXIA 4RG1A 1UALA 3KY7A 3DCMX 4JWGA 1X7OA 1WRPR 5GMCA 4JALA 1OY5A 4YQGA
chains in the Genus database with same CATH topology
4JWFA 4CNGA 4YQAA 4YQ7A 3L8UA 3ONPA 4KDZA 4E8BA 1ZJRA 3E5YA 4YQ5A 1Z85A 4YQKA 4CNEA 4MCCA 2EGVA 4YVIA 3KTYA 3AIAA 4YQJA 3OIIA 1V2XA 3KNUA 3BBEA 4H3ZA 4YQ2A 1UAJA 4YVGA 1TO0A 1VH0A 2V3KA 2Z0YA 2I6DA 3GYQA 3IC6A 4FAKA 4XBOA 3QUVA 1IPAA 2EGWA 4KGNA 4YQCA 4YQ8A 4JWJA 4YQSA 4MCDA 4IG6A 4YQ9A 1P9PA 3O7BA 1GZ0A 3N4JA 4MCBA 1UAMA 3BBHA 4FMWA 2CX8A 4J3CA 4YQ4A 4L69A 5FAIA 3BBDA 2QMMA 1K3RA 4YQ3A 4YQNA 3OIJA 3NK7A 4YQQA 4CNFA 3KW2A 1O6DA 4YQ6A 2QWVA 4JWHA 1NXZA 5D9FA 5GMBA 4YPZA 4YQTA 2YY8A 4YPYA 4YQRA 1V6ZA 4X3MA 4YQPA 3ILKA 4PZKA 4YPWA 4YQ0A 1VHYA 3N4KA 3IEFA 3OINA 4YQ1A 1X7PA 4YQIA 1J85A 4YQBA 4JAKA 1UAKA 4YQOA 4YQDA 1NS5A 2V3JA 4YQLA 4YVKA 2O3AA 5GM8A 4YVHA 4H3YA 2HA8A 3AXZA 4X3LA 3AI9X 4YPXA 4YVJA 4CNDA 5CO4A 3NK6A 1VHKA 1MXIA 4RG1A 1UALA 3KY7A 3DCMX 4JWGA 1X7OA 5GMCA 4JALA 1OY5A 4YQGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4CNG A;  4YQA A;  4YQ7 A;  3L8U A;  3ONP A;  4KDZ A;  4E8B A;  1ZJR A;  3E5Y A;  4YQ5 A;  1Z85 A;  4YQK A;  4CNE A;  4MCC A;  2EGV A;  4YVI A;  3KTY A;  3AIA A;  4YQJ A;  3OII A;  1V2X A;  3KNU A;  3BBE A;  4H3Z A;  4YQ2 A;  1UAJ A;  4YVG A;  1TO0 A;  1VH0 A;  2V3K A;  2Z0Y A;  2I6D A;  3GYQ A;  3IC6 A;  4FAK A;  4XBO A;  3QUV A;  1IPA A;  2EGW A;  4KGN A;  4YQC A;  4YQ8 A;  4YQS A;  4MCD A;  4IG6 A;  4YQ9 A;  1P9P A;  3O7B A;  1GZ0 A;  3N4J A;  4MCB A;  1UAM A;  3BBH A;  2CX8 A;  4J3C A;  4YQ4 A;  4L69 A;  5FAI A;  3BBD A;  2QMM A;  1K3R A;  4YQ3 A;  4YQN A;  3OIJ A;  3NK7 A;  4YQQ A;  4CNF A;  3KW2 A;  1O6D A;  4YQ6 A;  2QWV A;  1NXZ A;  5D9F A;  5GMB A;  4YPZ A;  4YQT A;  2YY8 A;  4YPY A;  4YQR A;  1V6Z A;  4X3M A;  4YQP A;  3ILK A;  4PZK A;  4YPW A;  4YQ0 A;  1VHY A;  3N4K A;  3IEF A;  3OIN A;  4YQ1 A;  1X7P A;  4YQI A;  1J85 A;  4YQB A;  4JAK A;  1UAK A;  4YQO A;  4YQD A;  1NS5 A;  2V3J A;  4YQL A;  4YVK A;  2O3A A;  5GM8 A;  4YVH A;  4H3Y A;  2HA8 A;  3AXZ A;  4X3L A;  3AI9 X;  4YPX A;  4YVJ A;  4CND A;  5CO4 A;  3NK6 A;  1VHK A;  1MXI A;  4RG1 A;  1UAL A;  3KY7 A;  3DCM X;  1X7O A;  5GMC A;  4JAL A;  1OY5 A;  4YQG A; 
#chains in the Genus database with same CATH topology
 1WRT R;  4JWF A;  4CNG A;  4YQA A;  4YQ7 A;  3L8U A;  3ONP A;  4KDZ A;  4E8B A;  1ZJR A;  3E5Y A;  4YQ5 A;  1Z85 A;  4YQK A;  4CNE A;  4MCC A;  2EGV A;  4YVI A;  1MI7 R;  3SSX N;  3KTY A;  3AIA A;  1RCS A;  4YQJ A;  3OII A;  1V2X A;  3KNU A;  3BBE A;  4H3Z A;  3SSW N;  4YQ2 A;  1JHG A;  1UAJ A;  4YVG A;  1TO0 A;  1VH0 A;  2V3K A;  2Z0Y A;  2I6D A;  3GYQ A;  3IC6 A;  4FAK A;  4XBO A;  3QUV A;  1IPA A;  2EGW A;  4KGN A;  4YQC A;  4YQ8 A;  4JWJ A;  4YQS A;  4IG6 A;  4MCD A;  2OZ9 R;  1P9P A;  4YQ9 A;  3O7B A;  1GZ0 A;  3FRW A;  4MCB A;  2XDI A;  3N4J A;  1UAM A;  3BBH A;  4FMW A;  2CX8 A;  4J3C A;  4YQ4 A;  4L69 A;  5FAI A;  3BBD A;  2QMM A;  1CO0 A;  1K3R A;  4YQ3 A;  4YQN A;  3OIJ A;  3NK7 A;  4YQQ A;  4CNF A;  1TRO A;  3G1C A;  3KW2 A;  1O6D A;  4YQ6 A;  2QWV A;  4JWH A;  1NXZ A;  1TRR A;  3WRP A;  5D9F A;  5GMB A;  4YPZ A;  4YQT A;  2YY8 A;  1WRS R;  4YPY A;  4YQR A;  1V6Z A;  4X3M A;  4YQP A;  3ILK A;  4PZK A;  4YPW A;  4YQ0 A;  1VHY A;  3N4K A;  3IEF A;  3OIN A;  4YQ1 A;  1X7P A;  3KOR A;  4YQI A;  1ZT9 A;  1J85 A;  4YQB A;  4JAK A;  1UAK A;  4YQO A;  4YQD A;  1NS5 A;  2V3J A;  4YQL A;  4YVK A;  2O3A A;  5GM8 A;  4YVH A;  4H3Y A;  2HA8 A;  3AXZ A;  4X3L A;  3AI9 X;  4YPX A;  4YVJ A;  4CND A;  5CO4 A;  3NK6 A;  1VHK A;  1MXI A;  4RG1 A;  1UAL A;  3KY7 A;  3DCM X;  4JWG A;  1X7O A;  1WRP R;  5GMC A;  4JAL A;  1OY5 A;  4YQG A; 
#chains in the Genus database with same CATH homology
 4JWF A;  4CNG A;  4YQA A;  4YQ7 A;  3L8U A;  3ONP A;  4KDZ A;  4E8B A;  1ZJR A;  3E5Y A;  4YQ5 A;  1Z85 A;  4YQK A;  4CNE A;  4MCC A;  2EGV A;  4YVI A;  3KTY A;  3AIA A;  4YQJ A;  3OII A;  1V2X A;  3KNU A;  3BBE A;  4H3Z A;  4YQ2 A;  1UAJ A;  4YVG A;  1TO0 A;  1VH0 A;  2V3K A;  2Z0Y A;  2I6D A;  3GYQ A;  3IC6 A;  4FAK A;  4XBO A;  3QUV A;  1IPA A;  2EGW A;  4KGN A;  4YQC A;  4YQ8 A;  4JWJ A;  4YQS A;  4MCD A;  4IG6 A;  4YQ9 A;  1P9P A;  3O7B A;  1GZ0 A;  3N4J A;  4MCB A;  1UAM A;  3BBH A;  4FMW A;  2CX8 A;  4J3C A;  4YQ4 A;  4L69 A;  5FAI A;  3BBD A;  2QMM A;  1K3R A;  4YQ3 A;  4YQN A;  3OIJ A;  3NK7 A;  4YQQ A;  4CNF A;  3KW2 A;  1O6D A;  4YQ6 A;  2QWV A;  4JWH A;  1NXZ A;  5D9F A;  5GMB A;  4YPZ A;  4YQT A;  2YY8 A;  4YPY A;  4YQR A;  1V6Z A;  4X3M A;  4YQP A;  3ILK A;  4PZK A;  4YPW A;  4YQ0 A;  1VHY A;  3N4K A;  3IEF A;  3OIN A;  4YQ1 A;  1X7P A;  4YQI A;  1J85 A;  4YQB A;  4JAK A;  1UAK A;  4YQO A;  4YQD A;  1NS5 A;  2V3J A;  4YQL A;  4YVK A;  2O3A A;  5GM8 A;  4YVH A;  4H3Y A;  2HA8 A;  3AXZ A;  4X3L A;  3AI9 X;  4YPX A;  4YVJ A;  4CND A;  5CO4 A;  3NK6 A;  1VHK A;  1MXI A;  4RG1 A;  1UAL A;  3KY7 A;  3DCM X;  4JWG A;  1X7O A;  5GMC A;  4JAL A;  1OY5 A;  4YQG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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