3QUVA

Crystal structure of a trna-guanine-n1-methyltransferase from mycobacterium abscessus
Total Genus 56
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
Knots found
sequence length
229
structure length
216
Chain Sequence
GSMKIDVVTIFPEYLQPVRQSLPGKAIDAGLVDVAVHDLRRWTHDVHKSVDDSPYGGGPGMVMKPTVWGDALDEICTSETLLVVPTPAGYPFTQETAWQWSTEDHLVIACGRYEGIDQRVADDAATRMRVREVSIGDYVLNGGEAAALVIIEAVLRLVPGVLGNASLLEGPSYTRPPSWRGMDVPPVLLSGDHAKIAAWRAEQSRQRTIERRPDLL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Increasing the structural coverage of tuberculosis drug targets.
pubmed doi rcsb
molecule tags Transferase
source organism Mycobacterium abscessus
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 56
structure length 216
sequence length 229
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.31: Transferred entry: 2.1.1.221 and 2.1.1.228.
pdb deposition date 2011-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 3quvA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 3quvA01
3BBDA 4YQPA 2CX8A 4YQ4A 3OINA 4YQ8A 4YPZA 2V3KA 2Z0YA 2O3AA 1V2XA 3OIJA 4YVKA 4J3CA 4JALA 2I6DA 3AIAA 1NXZA 1UAKA 4CNEA 1MXIA 1UAMA 1OY5A 5CO4A 4YQ3A 3AXZA 4YVHA 3NK7A 1P9PA 3ILKA 4IG6A 4H3YA 3E5YA 1X7OA 1UALA 1VH0A 4YQ1A 4YPXA 1NS5A 4YVGA 2EGVA 3KY7A 1UAJA 5FAIA 3N4JA 1IPAA 3ONPA 4CNGA 1VHKA 2QWVA 4YQQA 4YQ7A 4YQTA 3GYQA 4CNFA 4MCDA 3KW2A 3BBHA 4YQCA 3N4KA 4YPYA 4YQ5A 2HA8A 4YQAA 4CNDA 4X3LA 4YQDA 4YQLA 4YQBA 3KNUA 4YPWA 4YQ0A 4RG1A 4E8BA 4YQIA 4L69A 3NK6A 4X3MA 4MCBA 4MCCA 4KDZA 1TO0A 3L8UA 4H3ZA 4YQOA 4KGNA 2V3JA 4YQRA 4JAKA 2YY8A 5D9FA 5GMBA 2EGWA 3IEFA 3O7BA 3AI9X 1VHYA 1X7PA 1O6DA 4YQNA 3DCMX 5GM8A 4FAKA 3KTYA 4YQJA 1ZJRA 4YQ2A 4PZKA 4YQ6A 1Z85A 2QMMA 3OIIA 3BBEA 4YQ9A 3QUVA 1V6ZA 1GZ0A 4YQKA 4YVIA 4YQGA 5GMCA 1J85A 4YQSA 3IC6A 4XBOA 1K3RA 4YVJA
chains in the Genus database with same CATH superfamily
3KORA 3BBDA 4YQPA 1ZT9A 2CX8A 4YQ4A 3OINA 4YQ8A 4YPZA 2V3KA 2Z0YA 2O3AA 1V2XA 1WRTR 3OIJA 4YVKA 4J3CA 4JALA 2XDIA 2I6DA 3AIAA 1NXZA 1UAKA 4CNEA 1MXIA 1UAMA 4FMWA 1OY5A 5CO4A 4YQ3A 3AXZA 4YVHA 3NK7A 1P9PA 1CO0A 3ILKA 4IG6A 1RCSA 4H3YA 3E5YA 1X7OA 1UALA 1VH0A 4YQ1A 4YPXA 4JWJA 1NS5A 4YVGA 2EGVA 3KY7A 1UAJA 4JWHA 5FAIA 3N4JA 4JWFA 1IPAA 3ONPA 4CNGA 1VHKA 2QWVA 1TROA 2OZ9R 4YQQA 4YQ7A 4YQTA 3GYQA 4CNFA 4MCDA 1WRPR 3KW2A 3BBHA 4YQCA 3WRPA 3N4KA 4YPYA 4YQ5A 2HA8A 4YQAA 4CNDA 4X3LA 4YQDA 4YQLA 1WRSR 4YQBA 3KNUA 4YPWA 4YQ0A 4RG1A 4E8BA 4YQIA 4L69A 3G1CA 3NK6A 4X3MA 4MCBA 4MCCA 4KDZA 1TO0A 3L8UA 4H3ZA 4YQOA 4KGNA 2V3JA 4YQRA 4JAKA 1TRRA 3SSXN 2YY8A 5D9FA 5GMBA 2EGWA 3IEFA 3O7BA 3AI9X 1VHYA 1X7PA 1JHGA 1O6DA 4YQNA 3DCMX 3SSWN 5GM8A 4FAKA 3KTYA 4YQJA 1ZJRA 4YQ2A 4PZKA 4YQ6A 1Z85A 2QMMA 3OIIA 3BBEA 3FRWA 4YQ9A 4JWGA 3QUVA 1V6ZA 1GZ0A 4YQKA 1MI7R 4YVIA 4YQGA 5GMCA 1J85A 4YQSA 3IC6A 4XBOA 1K3RA 4YVJA
chains in the Genus database with same CATH topology
3BBDA 4YQPA 2CX8A 4YQ4A 3OINA 4YQ8A 4YPZA 2V3KA 2Z0YA 2O3AA 1V2XA 3OIJA 4YVKA 4J3CA 4JALA 2I6DA 3AIAA 1NXZA 1UAKA 4CNEA 1MXIA 1UAMA 4FMWA 1OY5A 5CO4A 4YQ3A 3AXZA 4YVHA 3NK7A 1P9PA 3ILKA 4IG6A 4H3YA 3E5YA 1X7OA 1UALA 1VH0A 4YQ1A 4YPXA 4JWJA 1NS5A 4YVGA 2EGVA 3KY7A 1UAJA 4JWHA 5FAIA 3N4JA 4JWFA 1IPAA 3ONPA 4CNGA 1VHKA 2QWVA 4YQQA 4YQ7A 4YQTA 3GYQA 4CNFA 4MCDA 3KW2A 3BBHA 4YQCA 3N4KA 4YPYA 4YQ5A 2HA8A 4YQAA 4CNDA 4X3LA 4YQDA 4YQLA 4YQBA 3KNUA 4YPWA 4YQ0A 4RG1A 4E8BA 4YQIA 4L69A 3NK6A 4X3MA 4MCBA 4MCCA 4KDZA 1TO0A 3L8UA 4H3ZA 4YQOA 4KGNA 2V3JA 4YQRA 4JAKA 2YY8A 5D9FA 5GMBA 2EGWA 3IEFA 3O7BA 3AI9X 1VHYA 1X7PA 1O6DA 4YQNA 3DCMX 5GM8A 4FAKA 3KTYA 4YQJA 1ZJRA 4YQ2A 4PZKA 4YQ6A 1Z85A 2QMMA 3OIIA 3BBEA 4YQ9A 4JWGA 3QUVA 1V6ZA 1GZ0A 4YQKA 4YVIA 4YQGA 5GMCA 1J85A 4YQSA 3IC6A 4XBOA 1K3RA 4YVJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BBD A;  4YQP A;  2CX8 A;  4YQ4 A;  3OIN A;  4YQ8 A;  4YPZ A;  2V3K A;  2Z0Y A;  2O3A A;  1V2X A;  3OIJ A;  4YVK A;  4J3C A;  4JAL A;  2I6D A;  3AIA A;  1NXZ A;  1UAK A;  4CNE A;  1MXI A;  1UAM A;  1OY5 A;  5CO4 A;  4YQ3 A;  3AXZ A;  4YVH A;  3NK7 A;  1P9P A;  3ILK A;  4IG6 A;  4H3Y A;  3E5Y A;  1X7O A;  1UAL A;  1VH0 A;  4YQ1 A;  4YPX A;  1NS5 A;  4YVG A;  2EGV A;  3KY7 A;  1UAJ A;  5FAI A;  3N4J A;  1IPA A;  3ONP A;  4CNG A;  1VHK A;  2QWV A;  4YQQ A;  4YQ7 A;  4YQT A;  3GYQ A;  4CNF A;  4MCD A;  3KW2 A;  3BBH A;  4YQC A;  3N4K A;  4YPY A;  4YQ5 A;  2HA8 A;  4YQA A;  4CND A;  4X3L A;  4YQD A;  4YQL A;  4YQB A;  3KNU A;  4YPW A;  4YQ0 A;  4RG1 A;  4E8B A;  4YQI A;  4L69 A;  3NK6 A;  4X3M A;  4MCB A;  4MCC A;  4KDZ A;  1TO0 A;  3L8U A;  4H3Z A;  4YQO A;  4KGN A;  2V3J A;  4YQR A;  4JAK A;  2YY8 A;  5D9F A;  5GMB A;  2EGW A;  3IEF A;  3O7B A;  3AI9 X;  1VHY A;  1X7P A;  1O6D A;  4YQN A;  3DCM X;  5GM8 A;  4FAK A;  3KTY A;  4YQJ A;  1ZJR A;  4YQ2 A;  4PZK A;  4YQ6 A;  1Z85 A;  2QMM A;  3OII A;  3BBE A;  4YQ9 A;  3QUV A;  1V6Z A;  1GZ0 A;  4YQK A;  4YVI A;  4YQG A;  5GMC A;  1J85 A;  4YQS A;  3IC6 A;  4XBO A;  1K3R A;  4YVJ A; 
#chains in the Genus database with same CATH topology
 3KOR A;  3BBD A;  4YQP A;  1ZT9 A;  2CX8 A;  4YQ4 A;  3OIN A;  4YQ8 A;  4YPZ A;  2V3K A;  2Z0Y A;  2O3A A;  1V2X A;  1WRT R;  3OIJ A;  4YVK A;  4J3C A;  4JAL A;  2XDI A;  2I6D A;  3AIA A;  1NXZ A;  1UAK A;  4CNE A;  1MXI A;  1UAM A;  4FMW A;  1OY5 A;  5CO4 A;  4YQ3 A;  3AXZ A;  4YVH A;  3NK7 A;  1P9P A;  1CO0 A;  3ILK A;  4IG6 A;  1RCS A;  4H3Y A;  3E5Y A;  1X7O A;  1UAL A;  1VH0 A;  4YQ1 A;  4YPX A;  4JWJ A;  1NS5 A;  4YVG A;  2EGV A;  3KY7 A;  1UAJ A;  4JWH A;  5FAI A;  3N4J A;  4JWF A;  1IPA A;  3ONP A;  4CNG A;  1VHK A;  2QWV A;  1TRO A;  2OZ9 R;  4YQQ A;  4YQ7 A;  4YQT A;  3GYQ A;  4CNF A;  4MCD A;  1WRP R;  3KW2 A;  3BBH A;  4YQC A;  3WRP A;  3N4K A;  4YPY A;  4YQ5 A;  2HA8 A;  4YQA A;  4CND A;  4X3L A;  4YQD A;  4YQL A;  1WRS R;  4YQB A;  3KNU A;  4YPW A;  4YQ0 A;  4RG1 A;  4E8B A;  4YQI A;  4L69 A;  3G1C A;  3NK6 A;  4X3M A;  4MCB A;  4MCC A;  4KDZ A;  1TO0 A;  3L8U A;  4H3Z A;  4YQO A;  4KGN A;  2V3J A;  4YQR A;  4JAK A;  1TRR A;  3SSX N;  2YY8 A;  5D9F A;  5GMB A;  2EGW A;  3IEF A;  3O7B A;  3AI9 X;  1VHY A;  1X7P A;  1JHG A;  1O6D A;  4YQN A;  3DCM X;  3SSW N;  5GM8 A;  4FAK A;  3KTY A;  4YQJ A;  1ZJR A;  4YQ2 A;  4PZK A;  4YQ6 A;  1Z85 A;  2QMM A;  3OII A;  3BBE A;  3FRW A;  4YQ9 A;  4JWG A;  3QUV A;  1V6Z A;  1GZ0 A;  4YQK A;  1MI7 R;  4YVI A;  4YQG A;  5GMC A;  1J85 A;  4YQS A;  3IC6 A;  4XBO A;  1K3R A;  4YVJ A; 
#chains in the Genus database with same CATH homology
 3BBD A;  4YQP A;  2CX8 A;  4YQ4 A;  3OIN A;  4YQ8 A;  4YPZ A;  2V3K A;  2Z0Y A;  2O3A A;  1V2X A;  3OIJ A;  4YVK A;  4J3C A;  4JAL A;  2I6D A;  3AIA A;  1NXZ A;  1UAK A;  4CNE A;  1MXI A;  1UAM A;  4FMW A;  1OY5 A;  5CO4 A;  4YQ3 A;  3AXZ A;  4YVH A;  3NK7 A;  1P9P A;  3ILK A;  4IG6 A;  4H3Y A;  3E5Y A;  1X7O A;  1UAL A;  1VH0 A;  4YQ1 A;  4YPX A;  4JWJ A;  1NS5 A;  4YVG A;  2EGV A;  3KY7 A;  1UAJ A;  4JWH A;  5FAI A;  3N4J A;  4JWF A;  1IPA A;  3ONP A;  4CNG A;  1VHK A;  2QWV A;  4YQQ A;  4YQ7 A;  4YQT A;  3GYQ A;  4CNF A;  4MCD A;  3KW2 A;  3BBH A;  4YQC A;  3N4K A;  4YPY A;  4YQ5 A;  2HA8 A;  4YQA A;  4CND A;  4X3L A;  4YQD A;  4YQL A;  4YQB A;  3KNU A;  4YPW A;  4YQ0 A;  4RG1 A;  4E8B A;  4YQI A;  4L69 A;  3NK6 A;  4X3M A;  4MCB A;  4MCC A;  4KDZ A;  1TO0 A;  3L8U A;  4H3Z A;  4YQO A;  4KGN A;  2V3J A;  4YQR A;  4JAK A;  2YY8 A;  5D9F A;  5GMB A;  2EGW A;  3IEF A;  3O7B A;  3AI9 X;  1VHY A;  1X7P A;  1O6D A;  4YQN A;  3DCM X;  5GM8 A;  4FAK A;  3KTY A;  4YQJ A;  1ZJR A;  4YQ2 A;  4PZK A;  4YQ6 A;  1Z85 A;  2QMM A;  3OII A;  3BBE A;  4YQ9 A;  4JWG A;  3QUV A;  1V6Z A;  1GZ0 A;  4YQK A;  4YVI A;  4YQG A;  5GMC A;  1J85 A;  4YQS A;  3IC6 A;  4XBO A;  1K3R A;  4YVJ A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...