4H3YA

Crystal structure of an asymmetric dimer of a trna (guanine-(n(1)-)-methyltransferase from burkholderia phymatum bound to s-adenosyl homocystein in one half-site
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
Knots found
sequence length
255
structure length
255
Chain Sequence
SMQFDIVTLFPDMFRALTDWGITSRAAKQERYGLRTWNPRDFTTDNYRTIDDRPYGGGPGMVMLARPLEDAINAAKAAQAEQGIGGARVVMMSPQGATLNHDKVMRFAAEPGLILLCGRYEAIDQRLIDRVVDEEVSLGDFVLSGGELPAMALIDAVVRHLPGVLNDAQSAVQDSFVDGLLDCPHYTRPEEYDGVRVPDVLLGGHHAEIEQWRRREALRNTWLKRPDLIVQARKNKLLSRADEAWLASLAKDASK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Combining functional and structural genomics to sample the essential Burkholderia structome.
pubmed doi rcsb
molecule tags Transferase
source organism Burkholderia phymatum
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 77
structure length 255
sequence length 255
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2012-09-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4h3yA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4h3yA01
4YVGA 4YQ2A 1VHKA 4YQ8A 1X7OA 4YQLA 4YQ1A 2O3AA 4YQGA 3IC6A 4YVHA 4YQCA 4CNDA 3QUVA 4X3MA 4YQ4A 4MCBA 4YQNA 3BBHA 3NK6A 2QWVA 4KDZA 3O7BA 3N4JA 3KW2A 4JAKA 4H3ZA 3GYQA 4H3YA 4YQ6A 4XBOA 4PZKA 1P9PA 4YVKA 3OIIA 5GMBA 4CNGA 1TO0A 1K3RA 1UAKA 1Z85A 4RG1A 1ZJRA 4L69A 1NXZA 1X7PA 3AXZA 1V2XA 4CNEA 4YQOA 4YVIA 5FAIA 4YQ0A 4KGNA 3E5YA 4YQSA 4YQIA 4YPZA 4YQDA 3N4KA 2YY8A 4MCDA 4YQ9A 1J85A 1UAJA 4YPWA 3AI9X 1NS5A 1VH0A 2CX8A 2QMMA 4X3LA 3OIJA 3ILKA 4YQ5A 4YPYA 5D9FA 1V6ZA 3NK7A 1VHYA 2V3KA 4YQPA 4IG6A 3ONPA 4CNFA 4JALA 4YQKA 4YQAA 4YQ3A 3AIAA 3L8UA 1OY5A 1GZ0A 3OINA 3KY7A 1MXIA 3KTYA 3DCMX 4MCCA 3KNUA 2EGWA 5GM8A 5GMCA 4YVJA 4E8BA 2EGVA 2V3JA 4YQ7A 1UAMA 4YQBA 2HA8A 3BBDA 4YQTA 2I6DA 5CO4A 3BBEA 1O6DA 4YQQA 3IEFA 4J3CA 4YPXA 1IPAA 4FAKA 4YQJA 4YQRA 2Z0YA 1UALA
chains in the Genus database with same CATH superfamily
4YVGA 4YQ2A 1VHKA 4FMWA 4YQ8A 1X7OA 4YQLA 4YQ1A 2XDIA 2O3AA 3FRWA 3KORA 4YQGA 3IC6A 4YVHA 4JWHA 4YQCA 4CNDA 3QUVA 4X3MA 4YQ4A 4MCBA 4YQNA 3BBHA 3NK6A 2QWVA 4KDZA 3O7BA 3N4JA 3KW2A 4JAKA 1RCSA 4H3ZA 3GYQA 4H3YA 4YQ6A 4XBOA 4PZKA 1P9PA 4YVKA 3OIIA 5GMBA 4CNGA 1TO0A 1K3RA 1UAKA 1Z85A 1MI7R 4RG1A 1ZJRA 4L69A 1NXZA 1X7PA 3AXZA 3SSWN 1V2XA 1JHGA 4JWGA 4CNEA 3SSXN 4YQOA 4YVIA 5FAIA 4YQ0A 4KGNA 3E5YA 4YQSA 4YQIA 4YPZA 4YQDA 3N4KA 2YY8A 4MCDA 4YQ9A 1WRSR 1J85A 1UAJA 4YPWA 3AI9X 1NS5A 1VH0A 2CX8A 2QMMA 4X3LA 3OIJA 3ILKA 4YQ5A 4YPYA 1TROA 5D9FA 1V6ZA 3NK7A 1VHYA 2V3KA 4YQPA 4IG6A 3ONPA 4CNFA 4JALA 4YQKA 1WRPR 4YQAA 3G1CA 4YQ3A 3AIAA 3L8UA 1OY5A 1GZ0A 4JWJA 3OINA 3KY7A 1TRRA 1MXIA 3KTYA 3DCMX 4MCCA 3KNUA 2EGWA 5GM8A 5GMCA 1WRTR 4YVJA 4E8BA 2EGVA 2V3JA 4YQ7A 3WRPA 4JWFA 1CO0A 1UAMA 4YQBA 2HA8A 3BBDA 1ZT9A 4YQTA 2I6DA 5CO4A 2OZ9R 3BBEA 1O6DA 4YQQA 3IEFA 4J3CA 4YPXA 1IPAA 4FAKA 4YQJA 4YQRA 2Z0YA 1UALA
chains in the Genus database with same CATH topology
4YVGA 4YQ2A 1VHKA 4FMWA 4YQ8A 1X7OA 4YQLA 4YQ1A 2O3AA 4YQGA 3IC6A 4YVHA 4JWHA 4YQCA 4CNDA 3QUVA 4X3MA 4YQ4A 4MCBA 4YQNA 3BBHA 3NK6A 2QWVA 4KDZA 3O7BA 3N4JA 3KW2A 4JAKA 4H3ZA 3GYQA 4H3YA 4YQ6A 4XBOA 4PZKA 1P9PA 4YVKA 3OIIA 5GMBA 4CNGA 1TO0A 1K3RA 1UAKA 1Z85A 4RG1A 1ZJRA 4L69A 1NXZA 1X7PA 3AXZA 1V2XA 4JWGA 4CNEA 4YQOA 4YVIA 5FAIA 4YQ0A 4KGNA 3E5YA 4YQSA 4YQIA 4YPZA 4YQDA 3N4KA 2YY8A 4MCDA 4YQ9A 1J85A 1UAJA 4YPWA 3AI9X 1NS5A 1VH0A 2CX8A 2QMMA 4X3LA 3OIJA 3ILKA 4YQ5A 4YPYA 5D9FA 1V6ZA 3NK7A 1VHYA 2V3KA 4YQPA 4IG6A 3ONPA 4CNFA 4JALA 4YQKA 4YQAA 4YQ3A 3AIAA 3L8UA 1OY5A 1GZ0A 4JWJA 3OINA 3KY7A 1MXIA 3KTYA 3DCMX 4MCCA 3KNUA 2EGWA 5GM8A 5GMCA 4YVJA 4E8BA 2EGVA 2V3JA 4YQ7A 4JWFA 1UAMA 4YQBA 2HA8A 3BBDA 4YQTA 2I6DA 5CO4A 3BBEA 1O6DA 4YQQA 3IEFA 4J3CA 4YPXA 1IPAA 4FAKA 4YQJA 4YQRA 2Z0YA 1UALA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YVG A;  4YQ2 A;  1VHK A;  4YQ8 A;  1X7O A;  4YQL A;  4YQ1 A;  2O3A A;  4YQG A;  3IC6 A;  4YVH A;  4YQC A;  4CND A;  3QUV A;  4X3M A;  4YQ4 A;  4MCB A;  4YQN A;  3BBH A;  3NK6 A;  2QWV A;  4KDZ A;  3O7B A;  3N4J A;  3KW2 A;  4JAK A;  4H3Z A;  3GYQ A;  4H3Y A;  4YQ6 A;  4XBO A;  4PZK A;  1P9P A;  4YVK A;  3OII A;  5GMB A;  4CNG A;  1TO0 A;  1K3R A;  1UAK A;  1Z85 A;  4RG1 A;  1ZJR A;  4L69 A;  1NXZ A;  1X7P A;  3AXZ A;  1V2X A;  4CNE A;  4YQO A;  4YVI A;  5FAI A;  4YQ0 A;  4KGN A;  3E5Y A;  4YQS A;  4YQI A;  4YPZ A;  4YQD A;  3N4K A;  2YY8 A;  4MCD A;  4YQ9 A;  1J85 A;  1UAJ A;  4YPW A;  3AI9 X;  1NS5 A;  1VH0 A;  2CX8 A;  2QMM A;  4X3L A;  3OIJ A;  3ILK A;  4YQ5 A;  4YPY A;  5D9F A;  1V6Z A;  3NK7 A;  1VHY A;  2V3K A;  4YQP A;  4IG6 A;  3ONP A;  4CNF A;  4JAL A;  4YQK A;  4YQA A;  4YQ3 A;  3AIA A;  3L8U A;  1OY5 A;  1GZ0 A;  3OIN A;  3KY7 A;  1MXI A;  3KTY A;  3DCM X;  4MCC A;  3KNU A;  2EGW A;  5GM8 A;  5GMC A;  4YVJ A;  4E8B A;  2EGV A;  2V3J A;  4YQ7 A;  1UAM A;  4YQB A;  2HA8 A;  3BBD A;  4YQT A;  2I6D A;  5CO4 A;  3BBE A;  1O6D A;  4YQQ A;  3IEF A;  4J3C A;  4YPX A;  1IPA A;  4FAK A;  4YQJ A;  4YQR A;  2Z0Y A;  1UAL A; 
#chains in the Genus database with same CATH topology
 4YVG A;  4YQ2 A;  1VHK A;  4FMW A;  4YQ8 A;  1X7O A;  4YQL A;  4YQ1 A;  2XDI A;  2O3A A;  3FRW A;  3KOR A;  4YQG A;  3IC6 A;  4YVH A;  4JWH A;  4YQC A;  4CND A;  3QUV A;  4X3M A;  4YQ4 A;  4MCB A;  4YQN A;  3BBH A;  3NK6 A;  2QWV A;  4KDZ A;  3O7B A;  3N4J A;  3KW2 A;  4JAK A;  1RCS A;  4H3Z A;  3GYQ A;  4H3Y A;  4YQ6 A;  4XBO A;  4PZK A;  1P9P A;  4YVK A;  3OII A;  5GMB A;  4CNG A;  1TO0 A;  1K3R A;  1UAK A;  1Z85 A;  1MI7 R;  4RG1 A;  1ZJR A;  4L69 A;  1NXZ A;  1X7P A;  3AXZ A;  3SSW N;  1V2X A;  1JHG A;  4JWG A;  4CNE A;  3SSX N;  4YQO A;  4YVI A;  5FAI A;  4YQ0 A;  4KGN A;  3E5Y A;  4YQS A;  4YQI A;  4YPZ A;  4YQD A;  3N4K A;  2YY8 A;  4MCD A;  4YQ9 A;  1WRS R;  1J85 A;  1UAJ A;  4YPW A;  3AI9 X;  1NS5 A;  1VH0 A;  2CX8 A;  2QMM A;  4X3L A;  3OIJ A;  3ILK A;  4YQ5 A;  4YPY A;  1TRO A;  5D9F A;  1V6Z A;  3NK7 A;  1VHY A;  2V3K A;  4YQP A;  4IG6 A;  3ONP A;  4CNF A;  4JAL A;  4YQK A;  1WRP R;  4YQA A;  3G1C A;  4YQ3 A;  3AIA A;  3L8U A;  1OY5 A;  1GZ0 A;  4JWJ A;  3OIN A;  3KY7 A;  1TRR A;  1MXI A;  3KTY A;  3DCM X;  4MCC A;  3KNU A;  2EGW A;  5GM8 A;  5GMC A;  1WRT R;  4YVJ A;  4E8B A;  2EGV A;  2V3J A;  4YQ7 A;  3WRP A;  4JWF A;  1CO0 A;  1UAM A;  4YQB A;  2HA8 A;  3BBD A;  1ZT9 A;  4YQT A;  2I6D A;  5CO4 A;  2OZ9 R;  3BBE A;  1O6D A;  4YQQ A;  3IEF A;  4J3C A;  4YPX A;  1IPA A;  4FAK A;  4YQJ A;  4YQR A;  2Z0Y A;  1UAL A; 
#chains in the Genus database with same CATH homology
 4YVG A;  4YQ2 A;  1VHK A;  4FMW A;  4YQ8 A;  1X7O A;  4YQL A;  4YQ1 A;  2O3A A;  4YQG A;  3IC6 A;  4YVH A;  4JWH A;  4YQC A;  4CND A;  3QUV A;  4X3M A;  4YQ4 A;  4MCB A;  4YQN A;  3BBH A;  3NK6 A;  2QWV A;  4KDZ A;  3O7B A;  3N4J A;  3KW2 A;  4JAK A;  4H3Z A;  3GYQ A;  4H3Y A;  4YQ6 A;  4XBO A;  4PZK A;  1P9P A;  4YVK A;  3OII A;  5GMB A;  4CNG A;  1TO0 A;  1K3R A;  1UAK A;  1Z85 A;  4RG1 A;  1ZJR A;  4L69 A;  1NXZ A;  1X7P A;  3AXZ A;  1V2X A;  4JWG A;  4CNE A;  4YQO A;  4YVI A;  5FAI A;  4YQ0 A;  4KGN A;  3E5Y A;  4YQS A;  4YQI A;  4YPZ A;  4YQD A;  3N4K A;  2YY8 A;  4MCD A;  4YQ9 A;  1J85 A;  1UAJ A;  4YPW A;  3AI9 X;  1NS5 A;  1VH0 A;  2CX8 A;  2QMM A;  4X3L A;  3OIJ A;  3ILK A;  4YQ5 A;  4YPY A;  5D9F A;  1V6Z A;  3NK7 A;  1VHY A;  2V3K A;  4YQP A;  4IG6 A;  3ONP A;  4CNF A;  4JAL A;  4YQK A;  4YQA A;  4YQ3 A;  3AIA A;  3L8U A;  1OY5 A;  1GZ0 A;  4JWJ A;  3OIN A;  3KY7 A;  1MXI A;  3KTY A;  3DCM X;  4MCC A;  3KNU A;  2EGW A;  5GM8 A;  5GMC A;  4YVJ A;  4E8B A;  2EGV A;  2V3J A;  4YQ7 A;  4JWF A;  1UAM A;  4YQB A;  2HA8 A;  3BBD A;  4YQT A;  2I6D A;  5CO4 A;  3BBE A;  1O6D A;  4YQQ A;  3IEF A;  4J3C A;  4YPX A;  1IPA A;  4FAK A;  4YQJ A;  4YQR A;  2Z0Y A;  1UAL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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