4H3ZA

Crystal structure of a symmetric dimer of a trna (guanine-(n(1)-)-methyltransferase from burkholderia phymatum bound to s-adenosyl homocystein in both half-sites
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
Knots found
sequence length
255
structure length
249
Chain Sequence
SMQFDIVTLFPDMFRALTDWGITSRAAKQERYGLRTWNPRDFTTDNYRTIDDRPYGGGPGMVMLARPLEDAINAAKAAQAEQGIGGARVVMMSPQGATLNHDKVMRFAAEPGLILLCGRYEAIDQRLIDRVVDEEVSLGDFVLSGGELPAMALIDAVVRHLPGVLNQDSFVDGLLDCPHYTRPEEYDGVRVPDVLLGGHHAEIEQWRRREALRNTWLKRPDLIVQARKNKLLSRADEAWLASLAKDASK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Combining functional and structural genomics to sample the essential Burkholderia structome.
pubmed doi rcsb
molecule tags Transferase
source organism Burkholderia phymatum
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 81
structure length 249
sequence length 255
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2012-09-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4h3zA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4h3zA01
3KTYA 3BBDA 4RG1A 4YQQA 4YQ7A 1UALA 4YQAA 4IG6A 1NS5A 4JAKA 1O6DA 3ONPA 1K3RA 3IC6A 4YQ0A 1J85A 4CNEA 3KY7A 2EGVA 4MCCA 4YVJA 4YQ3A 1VH0A 1NXZA 3OINA 4YQPA 4YQJA 2CX8A 3KW2A 3NK6A 4YVGA 4YPYA 4YVIA 3N4JA 3QUVA 4YQSA 3BBHA 4YVHA 4FAKA 4KGNA 4YQDA 4MCBA 4CNFA 3O7BA 4E8BA 1VHYA 4KDZA 4XBOA 4CNGA 5D9FA 1P9PA 1OY5A 4L69A 3L8UA 2QMMA 5GM8A 4X3LA 3NK7A 4YQGA 4PZKA 4YQ1A 4YQ9A 2V3JA 3N4KA 4J3CA 2QWVA 1MXIA 4YQCA 4YQ4A 4YPWA 4YQBA 2V3KA 2HA8A 5CO4A 5FAIA 3E5YA 2EGWA 3IEFA 3AIAA 2O3AA 3KNUA 2Z0YA 1V6ZA 1X7PA 1X7OA 5GMCA 4YQ8A 3GYQA 4YQNA 2YY8A 3DCMX 4YQ2A 1IPAA 3ILKA 1TO0A 4YQOA 1GZ0A 3AI9X 4YPXA 1UAMA 5GMBA 3AXZA 4YQLA 3OIIA 4MCDA 4YQ5A 1UAJA 3BBEA 1UAKA 2I6DA 1Z85A 4YPZA 4X3MA 4YQTA 1VHKA 4JALA 1V2XA 4YQRA 4YVKA 4YQIA 1ZJRA 3OIJA 4H3ZA 4CNDA 4YQ6A 4YQKA 4H3YA
chains in the Genus database with same CATH superfamily
3KTYA 3BBDA 4RG1A 4YQQA 4JWFA 4YQ7A 1UALA 4YQAA 4IG6A 1NS5A 4JAKA 1O6DA 2OZ9R 3ONPA 4JWGA 1K3RA 1WRPR 3IC6A 4YQ0A 1J85A 4CNEA 3KY7A 2EGVA 4MCCA 4YVJA 4YQ3A 1VH0A 1NXZA 2XDIA 3OINA 4YQPA 4YQJA 2CX8A 1WRTR 3KW2A 3NK6A 4YVGA 4YPYA 4YVIA 3N4JA 4FMWA 3QUVA 4YQSA 3BBHA 4YVHA 4FAKA 4KGNA 4YQDA 4MCBA 4CNFA 1TROA 3O7BA 3KORA 4E8BA 1VHYA 1CO0A 4KDZA 4XBOA 4CNGA 5D9FA 1P9PA 1OY5A 4L69A 3L8UA 2QMMA 5GM8A 4X3LA 3NK7A 4YQGA 1TRRA 3SSWN 3FRWA 4PZKA 4YQ1A 4YQ9A 2V3JA 3N4KA 4J3CA 2QWVA 1MXIA 4YQCA 4YQ4A 4YPWA 1MI7R 4YQBA 2V3KA 2HA8A 4JWJA 5CO4A 1RCSA 5FAIA 3E5YA 3SSXN 2EGWA 3IEFA 3AIAA 2O3AA 3KNUA 2Z0YA 1V6ZA 1X7PA 1X7OA 5GMCA 4YQ8A 3GYQA 4YQNA 2YY8A 3DCMX 4YQ2A 1IPAA 3ILKA 1TO0A 4YQOA 1GZ0A 3AI9X 4YPXA 1UAMA 5GMBA 3AXZA 4YQLA 3OIIA 4MCDA 4YQ5A 1UAJA 3BBEA 1UAKA 2I6DA 1Z85A 4YPZA 4X3MA 1ZT9A 4YQTA 1VHKA 4JALA 1V2XA 4YQRA 3G1CA 4YVKA 4JWHA 4YQIA 1ZJRA 1WRSR 3OIJA 4H3ZA 4CNDA 1JHGA 3WRPA 4YQ6A 4YQKA 4H3YA
chains in the Genus database with same CATH topology
3KTYA 3BBDA 4RG1A 4YQQA 4JWFA 4YQ7A 1UALA 4YQAA 4IG6A 1NS5A 4JAKA 1O6DA 3ONPA 4JWGA 1K3RA 3IC6A 4YQ0A 1J85A 4CNEA 3KY7A 2EGVA 4MCCA 4YVJA 4YQ3A 1VH0A 1NXZA 3OINA 4YQPA 4YQJA 2CX8A 3KW2A 3NK6A 4YVGA 4YPYA 4YVIA 3N4JA 4FMWA 3QUVA 4YQSA 3BBHA 4YVHA 4FAKA 4KGNA 4YQDA 4MCBA 4CNFA 3O7BA 4E8BA 1VHYA 4KDZA 4XBOA 4CNGA 5D9FA 1P9PA 1OY5A 4L69A 3L8UA 2QMMA 5GM8A 4X3LA 3NK7A 4YQGA 4PZKA 4YQ1A 4YQ9A 2V3JA 3N4KA 4J3CA 2QWVA 1MXIA 4YQCA 4YQ4A 4YPWA 4YQBA 2V3KA 2HA8A 4JWJA 5CO4A 5FAIA 3E5YA 2EGWA 3IEFA 3AIAA 2O3AA 3KNUA 2Z0YA 1V6ZA 1X7PA 1X7OA 5GMCA 4YQ8A 3GYQA 4YQNA 2YY8A 3DCMX 4YQ2A 1IPAA 3ILKA 1TO0A 4YQOA 1GZ0A 3AI9X 4YPXA 1UAMA 5GMBA 3AXZA 4YQLA 3OIIA 4MCDA 4YQ5A 1UAJA 3BBEA 1UAKA 2I6DA 1Z85A 4YPZA 4X3MA 4YQTA 1VHKA 4JALA 1V2XA 4YQRA 4YVKA 4JWHA 4YQIA 1ZJRA 3OIJA 4H3ZA 4CNDA 4YQ6A 4YQKA 4H3YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KTY A;  3BBD A;  4RG1 A;  4YQQ A;  4YQ7 A;  1UAL A;  4YQA A;  4IG6 A;  1NS5 A;  4JAK A;  1O6D A;  3ONP A;  1K3R A;  3IC6 A;  4YQ0 A;  1J85 A;  4CNE A;  3KY7 A;  2EGV A;  4MCC A;  4YVJ A;  4YQ3 A;  1VH0 A;  1NXZ A;  3OIN A;  4YQP A;  4YQJ A;  2CX8 A;  3KW2 A;  3NK6 A;  4YVG A;  4YPY A;  4YVI A;  3N4J A;  3QUV A;  4YQS A;  3BBH A;  4YVH A;  4FAK A;  4KGN A;  4YQD A;  4MCB A;  4CNF A;  3O7B A;  4E8B A;  1VHY A;  4KDZ A;  4XBO A;  4CNG A;  5D9F A;  1P9P A;  1OY5 A;  4L69 A;  3L8U A;  2QMM A;  5GM8 A;  4X3L A;  3NK7 A;  4YQG A;  4PZK A;  4YQ1 A;  4YQ9 A;  2V3J A;  3N4K A;  4J3C A;  2QWV A;  1MXI A;  4YQC A;  4YQ4 A;  4YPW A;  4YQB A;  2V3K A;  2HA8 A;  5CO4 A;  5FAI A;  3E5Y A;  2EGW A;  3IEF A;  3AIA A;  2O3A A;  3KNU A;  2Z0Y A;  1V6Z A;  1X7P A;  1X7O A;  5GMC A;  4YQ8 A;  3GYQ A;  4YQN A;  2YY8 A;  3DCM X;  4YQ2 A;  1IPA A;  3ILK A;  1TO0 A;  4YQO A;  1GZ0 A;  3AI9 X;  4YPX A;  1UAM A;  5GMB A;  3AXZ A;  4YQL A;  3OII A;  4MCD A;  4YQ5 A;  1UAJ A;  3BBE A;  1UAK A;  2I6D A;  1Z85 A;  4YPZ A;  4X3M A;  4YQT A;  1VHK A;  4JAL A;  1V2X A;  4YQR A;  4YVK A;  4YQI A;  1ZJR A;  3OIJ A;  4H3Z A;  4CND A;  4YQ6 A;  4YQK A;  4H3Y A; 
#chains in the Genus database with same CATH topology
 3KTY A;  3BBD A;  4RG1 A;  4YQQ A;  4JWF A;  4YQ7 A;  1UAL A;  4YQA A;  4IG6 A;  1NS5 A;  4JAK A;  1O6D A;  2OZ9 R;  3ONP A;  4JWG A;  1K3R A;  1WRP R;  3IC6 A;  4YQ0 A;  1J85 A;  4CNE A;  3KY7 A;  2EGV A;  4MCC A;  4YVJ A;  4YQ3 A;  1VH0 A;  1NXZ A;  2XDI A;  3OIN A;  4YQP A;  4YQJ A;  2CX8 A;  1WRT R;  3KW2 A;  3NK6 A;  4YVG A;  4YPY A;  4YVI A;  3N4J A;  4FMW A;  3QUV A;  4YQS A;  3BBH A;  4YVH A;  4FAK A;  4KGN A;  4YQD A;  4MCB A;  4CNF A;  1TRO A;  3O7B A;  3KOR A;  4E8B A;  1VHY A;  1CO0 A;  4KDZ A;  4XBO A;  4CNG A;  5D9F A;  1P9P A;  1OY5 A;  4L69 A;  3L8U A;  2QMM A;  5GM8 A;  4X3L A;  3NK7 A;  4YQG A;  1TRR A;  3SSW N;  3FRW A;  4PZK A;  4YQ1 A;  4YQ9 A;  2V3J A;  3N4K A;  4J3C A;  2QWV A;  1MXI A;  4YQC A;  4YQ4 A;  4YPW A;  1MI7 R;  4YQB A;  2V3K A;  2HA8 A;  4JWJ A;  5CO4 A;  1RCS A;  5FAI A;  3E5Y A;  3SSX N;  2EGW A;  3IEF A;  3AIA A;  2O3A A;  3KNU A;  2Z0Y A;  1V6Z A;  1X7P A;  1X7O A;  5GMC A;  4YQ8 A;  3GYQ A;  4YQN A;  2YY8 A;  3DCM X;  4YQ2 A;  1IPA A;  3ILK A;  1TO0 A;  4YQO A;  1GZ0 A;  3AI9 X;  4YPX A;  1UAM A;  5GMB A;  3AXZ A;  4YQL A;  3OII A;  4MCD A;  4YQ5 A;  1UAJ A;  3BBE A;  1UAK A;  2I6D A;  1Z85 A;  4YPZ A;  4X3M A;  1ZT9 A;  4YQT A;  1VHK A;  4JAL A;  1V2X A;  4YQR A;  3G1C A;  4YVK A;  4JWH A;  4YQI A;  1ZJR A;  1WRS R;  3OIJ A;  4H3Z A;  4CND A;  1JHG A;  3WRP A;  4YQ6 A;  4YQK A;  4H3Y A; 
#chains in the Genus database with same CATH homology
 3KTY A;  3BBD A;  4RG1 A;  4YQQ A;  4JWF A;  4YQ7 A;  1UAL A;  4YQA A;  4IG6 A;  1NS5 A;  4JAK A;  1O6D A;  3ONP A;  4JWG A;  1K3R A;  3IC6 A;  4YQ0 A;  1J85 A;  4CNE A;  3KY7 A;  2EGV A;  4MCC A;  4YVJ A;  4YQ3 A;  1VH0 A;  1NXZ A;  3OIN A;  4YQP A;  4YQJ A;  2CX8 A;  3KW2 A;  3NK6 A;  4YVG A;  4YPY A;  4YVI A;  3N4J A;  4FMW A;  3QUV A;  4YQS A;  3BBH A;  4YVH A;  4FAK A;  4KGN A;  4YQD A;  4MCB A;  4CNF A;  3O7B A;  4E8B A;  1VHY A;  4KDZ A;  4XBO A;  4CNG A;  5D9F A;  1P9P A;  1OY5 A;  4L69 A;  3L8U A;  2QMM A;  5GM8 A;  4X3L A;  3NK7 A;  4YQG A;  4PZK A;  4YQ1 A;  4YQ9 A;  2V3J A;  3N4K A;  4J3C A;  2QWV A;  1MXI A;  4YQC A;  4YQ4 A;  4YPW A;  4YQB A;  2V3K A;  2HA8 A;  4JWJ A;  5CO4 A;  5FAI A;  3E5Y A;  2EGW A;  3IEF A;  3AIA A;  2O3A A;  3KNU A;  2Z0Y A;  1V6Z A;  1X7P A;  1X7O A;  5GMC A;  4YQ8 A;  3GYQ A;  4YQN A;  2YY8 A;  3DCM X;  4YQ2 A;  1IPA A;  3ILK A;  1TO0 A;  4YQO A;  1GZ0 A;  3AI9 X;  4YPX A;  1UAM A;  5GMB A;  3AXZ A;  4YQL A;  3OII A;  4MCD A;  4YQ5 A;  1UAJ A;  3BBE A;  1UAK A;  2I6D A;  1Z85 A;  4YPZ A;  4X3M A;  4YQT A;  1VHK A;  4JAL A;  1V2X A;  4YQR A;  4YVK A;  4JWH A;  4YQI A;  1ZJR A;  3OIJ A;  4H3Z A;  4CND A;  4YQ6 A;  4YQK A;  4H3Y A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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