4IG6A

Crystal structure of a trna (guanine-n1)-methyltransferase from anaplasma phagocytophilum bound to s-adenosylhomocysteine
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
Knots found
sequence length
223
structure length
223
Chain Sequence
SMIFNVLTIFPQMFPGPLGVSNLGSALKKGLWTLNVFDIRAFANNKHNTVDDTPYGGGPGMLLRADVLGRCIDEVLSLHPNTKLMFTSPRGVSFTQDIARQTMNFDNITLLCGRFEGIDERVVDFYKLQEVSIGDYVLSGGELAAMVIIDTCVRMVPGVIGNAESLKQESMEGSLEYPQYTRPASWKGMEVPEVLLTGNHGEIEKWRRNASLSITAARRPDLL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
source organism Anaplasma phagocytophilum
publication title Crystal structure of a tRNA (guanine-N1)-methyltransferase from Anaplasma phagocytophilum bound to S-adenosylhomocysteine
rcsb
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 66
structure length 223
sequence length 223
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2012-12-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4ig6A02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4ig6A01
4L69A 4E8BA 1GZ0A 4YQIA 4CNGA 3L8UA 5FAIA 4CNEA 3N4KA 4YQ1A 3DCMX 4J3CA 1MXIA 2QMMA 3NK7A 4MCCA 2YY8A 1NS5A 1ZJRA 4YQNA 4KDZA 4X3LA 3N4JA 1J85A 2EGWA 3KY7A 1O6DA 1V6ZA 4YQ9A 4PZKA 4RG1A 4YQPA 1V2XA 1UAMA 4YQDA 3KW2A 3IEFA 3O7BA 4H3YA 4IG6A 1X7PA 4YQ6A 4YVIA 5GMBA 3GYQA 4YQKA 4YVJA 4KGNA 4MCBA 2HA8A 1UAKA 4YPXA 3ONPA 4YQGA 4YQJA 3QUVA 4YQRA 4YQ8A 4YQLA 4JAKA 3NK6A 1UALA 4YQ4A 3OIJA 4YQCA 4YQ7A 3ILKA 4FAKA 4YPYA 3OINA 1Z85A 2QWVA 4YQTA 2V3JA 5GM8A 4YQ5A 2Z0YA 4YQOA 3IC6A 4MCDA 4YVKA 4CNFA 4JALA 3KTYA 1IPAA 3AXZA 4CNDA 4XBOA 1UAJA 1TO0A 4YQQA 2V3KA 1OY5A 2O3AA 4YPZA 2I6DA 4YQAA 4YVGA 4YQ3A 1X7OA 3KNUA 3BBEA 2EGVA 4YQ2A 3BBHA 1VHKA 3BBDA 1P9PA 4YQSA 1VH0A 4H3ZA 3AIAA 4YQ0A 3OIIA 4X3MA 3AI9X 4YQBA 2CX8A 5D9FA 1VHYA 1NXZA 5CO4A 4YVHA 5GMCA 1K3RA 4YPWA 3E5YA
chains in the Genus database with same CATH superfamily
4L69A 4E8BA 1GZ0A 4YQIA 4CNGA 3L8UA 5FAIA 4CNEA 3N4KA 4YQ1A 3DCMX 4J3CA 1MXIA 2QMMA 3NK7A 4MCCA 2YY8A 1MI7R 1WRTR 1NS5A 1ZJRA 4YQNA 4KDZA 4X3LA 3N4JA 1J85A 2EGWA 3SSXN 3KY7A 1O6DA 1V6ZA 4YQ9A 4JWHA 4PZKA 4RG1A 4JWFA 4YQPA 1V2XA 1UAMA 4YQDA 3KW2A 3IEFA 3O7BA 4H3YA 3KORA 4IG6A 1X7PA 4YQ6A 4YVIA 5GMBA 3GYQA 4YQKA 1JHGA 4YVJA 4KGNA 4MCBA 2HA8A 2XDIA 1UAKA 4YPXA 3ONPA 4YQGA 4YQJA 3QUVA 1ZT9A 4YQRA 4YQ8A 4YQLA 1TRRA 4JAKA 3NK6A 1UALA 4YQ4A 3OIJA 4YQCA 4YQ7A 1WRSR 3ILKA 4FAKA 4YPYA 3OINA 1Z85A 2QWVA 4YQTA 2V3JA 5GM8A 4YQ5A 2Z0YA 4YQOA 3IC6A 4MCDA 4YVKA 1CO0A 4CNFA 4JALA 4JWJA 3KTYA 1IPAA 3AXZA 4CNDA 4XBOA 1UAJA 1TO0A 1TROA 4YQQA 2V3KA 1OY5A 2O3AA 3G1CA 4YPZA 3WRPA 3FRWA 2I6DA 4YQAA 4YVGA 4YQ3A 1X7OA 3KNUA 3BBEA 2EGVA 4YQ2A 3BBHA 1VHKA 3BBDA 1P9PA 4YQSA 4FMWA 1VH0A 4H3ZA 3AIAA 4YQ0A 3OIIA 4X3MA 3AI9X 4YQBA 2CX8A 5D9FA 1WRPR 1VHYA 1RCSA 1NXZA 5CO4A 3SSWN 4YVHA 5GMCA 4JWGA 1K3RA 2OZ9R 4YPWA 3E5YA
chains in the Genus database with same CATH topology
4L69A 4E8BA 1GZ0A 4YQIA 4CNGA 3L8UA 5FAIA 4CNEA 3N4KA 4YQ1A 3DCMX 4J3CA 1MXIA 2QMMA 3NK7A 4MCCA 2YY8A 1NS5A 1ZJRA 4YQNA 4KDZA 4X3LA 3N4JA 1J85A 2EGWA 3KY7A 1O6DA 1V6ZA 4YQ9A 4JWHA 4PZKA 4RG1A 4JWFA 4YQPA 1V2XA 1UAMA 4YQDA 3KW2A 3IEFA 3O7BA 4H3YA 4IG6A 1X7PA 4YQ6A 4YVIA 5GMBA 3GYQA 4YQKA 4YVJA 4KGNA 4MCBA 2HA8A 1UAKA 4YPXA 3ONPA 4YQGA 4YQJA 3QUVA 4YQRA 4YQ8A 4YQLA 4JAKA 3NK6A 1UALA 4YQ4A 3OIJA 4YQCA 4YQ7A 3ILKA 4FAKA 4YPYA 3OINA 1Z85A 2QWVA 4YQTA 2V3JA 5GM8A 4YQ5A 2Z0YA 4YQOA 3IC6A 4MCDA 4YVKA 4CNFA 4JALA 4JWJA 3KTYA 1IPAA 3AXZA 4CNDA 4XBOA 1UAJA 1TO0A 4YQQA 2V3KA 1OY5A 2O3AA 4YPZA 2I6DA 4YQAA 4YVGA 4YQ3A 1X7OA 3KNUA 3BBEA 2EGVA 4YQ2A 3BBHA 1VHKA 3BBDA 1P9PA 4YQSA 4FMWA 1VH0A 4H3ZA 3AIAA 4YQ0A 3OIIA 4X3MA 3AI9X 4YQBA 2CX8A 5D9FA 1VHYA 1NXZA 5CO4A 4YVHA 5GMCA 4JWGA 1K3RA 4YPWA 3E5YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4L69 A;  4E8B A;  1GZ0 A;  4YQI A;  4CNG A;  3L8U A;  5FAI A;  4CNE A;  3N4K A;  4YQ1 A;  3DCM X;  4J3C A;  1MXI A;  2QMM A;  3NK7 A;  4MCC A;  2YY8 A;  1NS5 A;  1ZJR A;  4YQN A;  4KDZ A;  4X3L A;  3N4J A;  1J85 A;  2EGW A;  3KY7 A;  1O6D A;  1V6Z A;  4YQ9 A;  4PZK A;  4RG1 A;  4YQP A;  1V2X A;  1UAM A;  4YQD A;  3KW2 A;  3IEF A;  3O7B A;  4H3Y A;  4IG6 A;  1X7P A;  4YQ6 A;  4YVI A;  5GMB A;  3GYQ A;  4YQK A;  4YVJ A;  4KGN A;  4MCB A;  2HA8 A;  1UAK A;  4YPX A;  3ONP A;  4YQG A;  4YQJ A;  3QUV A;  4YQR A;  4YQ8 A;  4YQL A;  4JAK A;  3NK6 A;  1UAL A;  4YQ4 A;  3OIJ A;  4YQC A;  4YQ7 A;  3ILK A;  4FAK A;  4YPY A;  3OIN A;  1Z85 A;  2QWV A;  4YQT A;  2V3J A;  5GM8 A;  4YQ5 A;  2Z0Y A;  4YQO A;  3IC6 A;  4MCD A;  4YVK A;  4CNF A;  4JAL A;  3KTY A;  1IPA A;  3AXZ A;  4CND A;  4XBO A;  1UAJ A;  1TO0 A;  4YQQ A;  2V3K A;  1OY5 A;  2O3A A;  4YPZ A;  2I6D A;  4YQA A;  4YVG A;  4YQ3 A;  1X7O A;  3KNU A;  3BBE A;  2EGV A;  4YQ2 A;  3BBH A;  1VHK A;  3BBD A;  1P9P A;  4YQS A;  1VH0 A;  4H3Z A;  3AIA A;  4YQ0 A;  3OII A;  4X3M A;  3AI9 X;  4YQB A;  2CX8 A;  5D9F A;  1VHY A;  1NXZ A;  5CO4 A;  4YVH A;  5GMC A;  1K3R A;  4YPW A;  3E5Y A; 
#chains in the Genus database with same CATH topology
 4L69 A;  4E8B A;  1GZ0 A;  4YQI A;  4CNG A;  3L8U A;  5FAI A;  4CNE A;  3N4K A;  4YQ1 A;  3DCM X;  4J3C A;  1MXI A;  2QMM A;  3NK7 A;  4MCC A;  2YY8 A;  1MI7 R;  1WRT R;  1NS5 A;  1ZJR A;  4YQN A;  4KDZ A;  4X3L A;  3N4J A;  1J85 A;  2EGW A;  3SSX N;  3KY7 A;  1O6D A;  1V6Z A;  4YQ9 A;  4JWH A;  4PZK A;  4RG1 A;  4JWF A;  4YQP A;  1V2X A;  1UAM A;  4YQD A;  3KW2 A;  3IEF A;  3O7B A;  4H3Y A;  3KOR A;  4IG6 A;  1X7P A;  4YQ6 A;  4YVI A;  5GMB A;  3GYQ A;  4YQK A;  1JHG A;  4YVJ A;  4KGN A;  4MCB A;  2HA8 A;  2XDI A;  1UAK A;  4YPX A;  3ONP A;  4YQG A;  4YQJ A;  3QUV A;  1ZT9 A;  4YQR A;  4YQ8 A;  4YQL A;  1TRR A;  4JAK A;  3NK6 A;  1UAL A;  4YQ4 A;  3OIJ A;  4YQC A;  4YQ7 A;  1WRS R;  3ILK A;  4FAK A;  4YPY A;  3OIN A;  1Z85 A;  2QWV A;  4YQT A;  2V3J A;  5GM8 A;  4YQ5 A;  2Z0Y A;  4YQO A;  3IC6 A;  4MCD A;  4YVK A;  1CO0 A;  4CNF A;  4JAL A;  4JWJ A;  3KTY A;  1IPA A;  3AXZ A;  4CND A;  4XBO A;  1UAJ A;  1TO0 A;  1TRO A;  4YQQ A;  2V3K A;  1OY5 A;  2O3A A;  3G1C A;  4YPZ A;  3WRP A;  3FRW A;  2I6D A;  4YQA A;  4YVG A;  4YQ3 A;  1X7O A;  3KNU A;  3BBE A;  2EGV A;  4YQ2 A;  3BBH A;  1VHK A;  3BBD A;  1P9P A;  4YQS A;  4FMW A;  1VH0 A;  4H3Z A;  3AIA A;  4YQ0 A;  3OII A;  4X3M A;  3AI9 X;  4YQB A;  2CX8 A;  5D9F A;  1WRP R;  1VHY A;  1RCS A;  1NXZ A;  5CO4 A;  3SSW N;  4YVH A;  5GMC A;  4JWG A;  1K3R A;  2OZ9 R;  4YPW A;  3E5Y A; 
#chains in the Genus database with same CATH homology
 4L69 A;  4E8B A;  1GZ0 A;  4YQI A;  4CNG A;  3L8U A;  5FAI A;  4CNE A;  3N4K A;  4YQ1 A;  3DCM X;  4J3C A;  1MXI A;  2QMM A;  3NK7 A;  4MCC A;  2YY8 A;  1NS5 A;  1ZJR A;  4YQN A;  4KDZ A;  4X3L A;  3N4J A;  1J85 A;  2EGW A;  3KY7 A;  1O6D A;  1V6Z A;  4YQ9 A;  4JWH A;  4PZK A;  4RG1 A;  4JWF A;  4YQP A;  1V2X A;  1UAM A;  4YQD A;  3KW2 A;  3IEF A;  3O7B A;  4H3Y A;  4IG6 A;  1X7P A;  4YQ6 A;  4YVI A;  5GMB A;  3GYQ A;  4YQK A;  4YVJ A;  4KGN A;  4MCB A;  2HA8 A;  1UAK A;  4YPX A;  3ONP A;  4YQG A;  4YQJ A;  3QUV A;  4YQR A;  4YQ8 A;  4YQL A;  4JAK A;  3NK6 A;  1UAL A;  4YQ4 A;  3OIJ A;  4YQC A;  4YQ7 A;  3ILK A;  4FAK A;  4YPY A;  3OIN A;  1Z85 A;  2QWV A;  4YQT A;  2V3J A;  5GM8 A;  4YQ5 A;  2Z0Y A;  4YQO A;  3IC6 A;  4MCD A;  4YVK A;  4CNF A;  4JAL A;  4JWJ A;  3KTY A;  1IPA A;  3AXZ A;  4CND A;  4XBO A;  1UAJ A;  1TO0 A;  4YQQ A;  2V3K A;  1OY5 A;  2O3A A;  4YPZ A;  2I6D A;  4YQA A;  4YVG A;  4YQ3 A;  1X7O A;  3KNU A;  3BBE A;  2EGV A;  4YQ2 A;  3BBH A;  1VHK A;  3BBD A;  1P9P A;  4YQS A;  4FMW A;  1VH0 A;  4H3Z A;  3AIA A;  4YQ0 A;  3OII A;  4X3M A;  3AI9 X;  4YQB A;  2CX8 A;  5D9F A;  1VHY A;  1NXZ A;  5CO4 A;  4YVH A;  5GMC A;  4JWG A;  1K3R A;  4YPW A;  3E5Y A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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