4IG6 | Genus

Total Genus 66

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	66
Knots found	KnotProt 2.0: K +3₁
sequence length	223
structure length	223
Chain Sequence	SMIFNVLTIFPQMFPGPLGVSNLGSALKKGLWTLNVFDIRAFANNKHNTVDDTPYGGGPGMLLRADVLGRCIDEVLSLHPNTKLMFTSPRGVSFTQDIARQTMNFDNITLLCGRFEGIDERVVDFYKLQEVSIGDYVLSGGELAAMVIIDTCVRMVPGVIGNAESLKQESMEGSLEYPQYTRPASWKGMEVPEVLLTGNHGEIEKWRRNASLSITAARRPDLL

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 223 atoms

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223 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transferase/transferase inhibitor
source organism	Anaplasma phagocytophilum
publication title	Crystal structure of a tRNA (guanine-N1)-methyltransferase from Anaplasma phagocytophilum bound to S-adenosylhomocysteine rcsb
molecule keywords	tRNA (guanine-N(1)-)-methyltransferase
total genus	66
structure length	223
sequence length	223
other databases	KnotProt 2.0: K +3₁
ec nomenclature	ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date	2012-12-16

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01746	tRNA_m1G_MT	tRNA (Guanine-1)-methyltransferase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.1270.20	Mainly Alpha	Orthogonal Bundle	Trp Operon Repressor; Chain A	tRNA(m1g37)methyltransferase, domain 2	4ig6A02
3.40.1280.10	Alpha Beta	3-Layer(aba) Sandwich	Alpha/beta knot	Alpha/beta knot	4ig6A01

4H3YA 5GM8A 4YPXA 4YQ9A 4YQLA 2EGWA 4YQ5A 4YQ3A 3AXZA 2YY8A 4CNGA 3AIAA 1VHYA 4YVIA 4YQIA 4JALA 3KW2A 3O7BA 4CNFA 5D9FA 1P9PA 1VHKA 1J85A 3AI9X 4YQ1A 3NK6A 1ZJRA 3IC6A 4YQTA 4YQOA 3L8UA 4FAKA 1GZ0A 4YQ2A 4YQAA 4YVGA 4JAKA 1Z85A 3DCMX 4YQCA 1O6DA 4YQKA 4MCDA 4YVHA 2Z0YA 4YQSA 3KY7A 4YPZA 4J3CA 3ILKA 5CO4A 1UAMA 3BBEA 3IEFA 1OY5A 2V3KA 4MCBA 4KDZA 4YQ0A 4YQ8A 4X3MA 4YQRA 4YQ7A 4CNDA 2V3JA 4YQ4A 1NS5A 3QUVA 4YPYA 1X7OA 4CNEA 3NK7A 4YVJA 4YVKA 4YQJA 4YQPA 3KTYA 1K3RA 3E5YA 4YPWA 3BBHA 5GMBA 1MXIA 1UAKA 4E8BA 2I6DA 1V6ZA 4YQNA 3ONPA 4YQ6A 2QWVA 3KNUA 3OIJA 4YQBA 4YQGA 5FAIA 1UAJA 1VH0A 2QMMA 3GYQA 4PZKA 1TO0A 1X7PA 2EGVA 4X3LA 1V2XA 4XBOA 4YQQA 3OINA 4MCCA 2HA8A 3BBDA 3N4KA 3N4JA 4KGNA 4L69A 1UALA 1IPAA 4H3ZA 3OIIA 5GMCA 2O3AA 4YQDA 4IG6A 2CX8A 4RG1A 1NXZA
chains in the Genus database with same CATH superfamily

3SSWN 3FRWA 4H3YA 5GM8A 4YPXA 4YQ9A 4FMWA 4YQLA 2EGWA 4YQ5A 1ZT9A 4YQ3A 3AXZA 3KORA 2YY8A 2OZ9R 4CNGA 3AIAA 1VHYA 4YVIA 4YQIA 4JALA 3KW2A 1MI7R 3O7BA 5D9FA 4CNFA 1P9PA 1WRSR 1VHKA 1J85A 3AI9X 1CO0A 4YQ1A 3NK6A 1ZJRA 3IC6A 4YQTA 4YQOA 3L8UA 4FAKA 4JWJA 1GZ0A 4YQ2A 4YQAA 4YVGA 4JAKA 1Z85A 3DCMX 4YQCA 1O6DA 4YQKA 4MCDA 4JWHA 4YVHA 2Z0YA 4YQSA 3KY7A 4YPZA 1WRPR 4J3CA 3ILKA 5CO4A 1UAMA 3BBEA 3IEFA 1OY5A 2V3KA 4MCBA 2XDIA 4KDZA 4YQ0A 4YQ8A 4X3MA 4YQRA 4YQ7A 4CNDA 2V3JA 4YQ4A 1NS5A 3QUVA 4YPYA 1X7OA 4CNEA 3NK7A 4YVJA 4YVKA 4YQJA 4YQPA 3KTYA 1K3RA 3E5YA 4YPWA 3BBHA 5GMBA 3G1CA 1MXIA 1UAKA 4E8BA 2I6DA 1V6ZA 4YQNA 3ONPA 1TROA 1TRRA 4YQ6A 2QWVA 3KNUA 1RCSA 3OIJA 4YQBA 4YQGA 5FAIA 1UAJA 1VH0A 2QMMA 3GYQA 4PZKA 1TO0A 1X7PA 2EGVA 4X3LA 1V2XA 4XBOA 4YQQA 3OINA 4MCCA 4JWGA 2HA8A 3BBDA 3SSXN 3N4KA 4JWFA 3N4JA 4KGNA 4L69A 1UALA 1IPAA 4H3ZA 3OIIA 5GMCA 2O3AA 4YQDA 4IG6A 2CX8A 3WRPA 4RG1A 1NXZA 1JHGA 1WRTR
chains in the Genus database with same CATH topology

4H3YA 5GM8A 4YPXA 4YQ9A 4FMWA 4YQLA 2EGWA 4YQ5A 4YQ3A 3AXZA 2YY8A 4CNGA 3AIAA 1VHYA 4YVIA 4YQIA 4JALA 3KW2A 3O7BA 4CNFA 5D9FA 1P9PA 1VHKA 1J85A 3AI9X 4YQ1A 3NK6A 1ZJRA 3IC6A 4YQTA 4YQOA 3L8UA 4FAKA 4JWJA 1GZ0A 4YQ2A 4YQAA 4YVGA 4JAKA 1Z85A 3DCMX 4YQCA 1O6DA 4YQKA 4MCDA 4JWHA 4YVHA 2Z0YA 4YQSA 3KY7A 4YPZA 4J3CA 3ILKA 5CO4A 1UAMA 3BBEA 3IEFA 1OY5A 2V3KA 4MCBA 4KDZA 4YQ0A 4YQ8A 4X3MA 4YQRA 4YQ7A 4CNDA 2V3JA 4YQ4A 1NS5A 3QUVA 4YPYA 1X7OA 4CNEA 3NK7A 4YVJA 4YVKA 4YQJA 4YQPA 3KTYA 1K3RA 3E5YA 4YPWA 3BBHA 5GMBA 1MXIA 1UAKA 4E8BA 2I6DA 1V6ZA 4YQNA 3ONPA 4YQ6A 2QWVA 3KNUA 3OIJA 4YQBA 4YQGA 5FAIA 1UAJA 1VH0A 2QMMA 3GYQA 4PZKA 1TO0A 1X7PA 2EGVA 4X3LA 1V2XA 4XBOA 4YQQA 3OINA 4MCCA 4JWGA 2HA8A 3BBDA 3N4KA 4JWFA 3N4JA 4KGNA 4L69A 1UALA 1IPAA 4H3ZA 3OIIA 5GMCA 2O3AA 4YQDA 4IG6A 2CX8A 4RG1A 1NXZA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 4H3Y A;  5GM8 A;  4YPX A;  4YQ9 A;  4YQL A;  2EGW A;  4YQ5 A;  4YQ3 A;  3AXZ A;  2YY8 A;  4CNG A;  3AIA A;  1VHY A;  4YVI A;  4YQI A;  4JAL A;  3KW2 A;  3O7B A;  4CNF A;  5D9F A;  1P9P A;  1VHK A;  1J85 A;  3AI9 X;  4YQ1 A;  3NK6 A;  1ZJR A;  3IC6 A;  4YQT A;  4YQO A;  3L8U A;  4FAK A;  1GZ0 A;  4YQ2 A;  4YQA A;  4YVG A;  4JAK A;  1Z85 A;  3DCM X;  4YQC A;  1O6D A;  4YQK A;  4MCD A;  4YVH A;  2Z0Y A;  4YQS A;  3KY7 A;  4YPZ A;  4J3C A;  3ILK A;  5CO4 A;  1UAM A;  3BBE A;  3IEF A;  1OY5 A;  2V3K A;  4MCB A;  4KDZ A;  4YQ0 A;  4YQ8 A;  4X3M A;  4YQR A;  4YQ7 A;  4CND A;  2V3J A;  4YQ4 A;  1NS5 A;  3QUV A;  4YPY A;  1X7O A;  4CNE A;  3NK7 A;  4YVJ A;  4YVK A;  4YQJ A;  4YQP A;  3KTY A;  1K3R A;  3E5Y A;  4YPW A;  3BBH A;  5GMB A;  1MXI A;  1UAK A;  4E8B A;  2I6D A;  1V6Z A;  4YQN A;  3ONP A;  4YQ6 A;  2QWV A;  3KNU A;  3OIJ A;  4YQB A;  4YQG A;  5FAI A;  1UAJ A;  1VH0 A;  2QMM A;  3GYQ A;  4PZK A;  1TO0 A;  1X7P A;  2EGV A;  4X3L A;  1V2X A;  4XBO A;  4YQQ A;  3OIN A;  4MCC A;  2HA8 A;  3BBD A;  3N4K A;  3N4J A;  4KGN A;  4L69 A;  1UAL A;  1IPA A;  4H3Z A;  3OII A;  5GMC A;  2O3A A;  4YQD A;  4IG6 A;  2CX8 A;  4RG1 A;  1NXZ A; 
#chains in the Genus database with same CATH topology
 3SSW N;  3FRW A;  4H3Y A;  5GM8 A;  4YPX A;  4YQ9 A;  4FMW A;  4YQL A;  2EGW A;  4YQ5 A;  1ZT9 A;  4YQ3 A;  3AXZ A;  3KOR A;  2YY8 A;  2OZ9 R;  4CNG A;  3AIA A;  1VHY A;  4YVI A;  4YQI A;  4JAL A;  3KW2 A;  1MI7 R;  3O7B A;  5D9F A;  4CNF A;  1P9P A;  1WRS R;  1VHK A;  1J85 A;  3AI9 X;  1CO0 A;  4YQ1 A;  3NK6 A;  1ZJR A;  3IC6 A;  4YQT A;  4YQO A;  3L8U A;  4FAK A;  4JWJ A;  1GZ0 A;  4YQ2 A;  4YQA A;  4YVG A;  4JAK A;  1Z85 A;  3DCM X;  4YQC A;  1O6D A;  4YQK A;  4MCD A;  4JWH A;  4YVH A;  2Z0Y A;  4YQS A;  3KY7 A;  4YPZ A;  1WRP R;  4J3C A;  3ILK A;  5CO4 A;  1UAM A;  3BBE A;  3IEF A;  1OY5 A;  2V3K A;  4MCB A;  2XDI A;  4KDZ A;  4YQ0 A;  4YQ8 A;  4X3M A;  4YQR A;  4YQ7 A;  4CND A;  2V3J A;  4YQ4 A;  1NS5 A;  3QUV A;  4YPY A;  1X7O A;  4CNE A;  3NK7 A;  4YVJ A;  4YVK A;  4YQJ A;  4YQP A;  3KTY A;  1K3R A;  3E5Y A;  4YPW A;  3BBH A;  5GMB A;  3G1C A;  1MXI A;  1UAK A;  4E8B A;  2I6D A;  1V6Z A;  4YQN A;  3ONP A;  1TRO A;  1TRR A;  4YQ6 A;  2QWV A;  3KNU A;  1RCS A;  3OIJ A;  4YQB A;  4YQG A;  5FAI A;  1UAJ A;  1VH0 A;  2QMM A;  3GYQ A;  4PZK A;  1TO0 A;  1X7P A;  2EGV A;  4X3L A;  1V2X A;  4XBO A;  4YQQ A;  3OIN A;  4MCC A;  4JWG A;  2HA8 A;  3BBD A;  3SSX N;  3N4K A;  4JWF A;  3N4J A;  4KGN A;  4L69 A;  1UAL A;  1IPA A;  4H3Z A;  3OII A;  5GMC A;  2O3A A;  4YQD A;  4IG6 A;  2CX8 A;  3WRP A;  4RG1 A;  1NXZ A;  1JHG A;  1WRT R; 
#chains in the Genus database with same CATH homology
 4H3Y A;  5GM8 A;  4YPX A;  4YQ9 A;  4FMW A;  4YQL A;  2EGW A;  4YQ5 A;  4YQ3 A;  3AXZ A;  2YY8 A;  4CNG A;  3AIA A;  1VHY A;  4YVI A;  4YQI A;  4JAL A;  3KW2 A;  3O7B A;  4CNF A;  5D9F A;  1P9P A;  1VHK A;  1J85 A;  3AI9 X;  4YQ1 A;  3NK6 A;  1ZJR A;  3IC6 A;  4YQT A;  4YQO A;  3L8U A;  4FAK A;  4JWJ A;  1GZ0 A;  4YQ2 A;  4YQA A;  4YVG A;  4JAK A;  1Z85 A;  3DCM X;  4YQC A;  1O6D A;  4YQK A;  4MCD A;  4JWH A;  4YVH A;  2Z0Y A;  4YQS A;  3KY7 A;  4YPZ A;  4J3C A;  3ILK A;  5CO4 A;  1UAM A;  3BBE A;  3IEF A;  1OY5 A;  2V3K A;  4MCB A;  4KDZ A;  4YQ0 A;  4YQ8 A;  4X3M A;  4YQR A;  4YQ7 A;  4CND A;  2V3J A;  4YQ4 A;  1NS5 A;  3QUV A;  4YPY A;  1X7O A;  4CNE A;  3NK7 A;  4YVJ A;  4YVK A;  4YQJ A;  4YQP A;  3KTY A;  1K3R A;  3E5Y A;  4YPW A;  3BBH A;  5GMB A;  1MXI A;  1UAK A;  4E8B A;  2I6D A;  1V6Z A;  4YQN A;  3ONP A;  4YQ6 A;  2QWV A;  3KNU A;  3OIJ A;  4YQB A;  4YQG A;  5FAI A;  1UAJ A;  1VH0 A;  2QMM A;  3GYQ A;  4PZK A;  1TO0 A;  1X7P A;  2EGV A;  4X3L A;  1V2X A;  4XBO A;  4YQQ A;  3OIN A;  4MCC A;  4JWG A;  2HA8 A;  3BBD A;  3N4K A;  4JWF A;  3N4J A;  4KGN A;  4L69 A;  1UAL A;  1IPA A;  4H3Z A;  3OII A;  5GMC A;  2O3A A;  4YQD A;  4IG6 A;  2CX8 A;  4RG1 A;  1NXZ A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4IG6A

Total Genus

Knots found

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations