4IG6A

Crystal structure of a trna (guanine-n1)-methyltransferase from anaplasma phagocytophilum bound to s-adenosylhomocysteine
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
Knots found
sequence length
223
structure length
223
Chain Sequence
SMIFNVLTIFPQMFPGPLGVSNLGSALKKGLWTLNVFDIRAFANNKHNTVDDTPYGGGPGMLLRADVLGRCIDEVLSLHPNTKLMFTSPRGVSFTQDIARQTMNFDNITLLCGRFEGIDERVVDFYKLQEVSIGDYVLSGGELAAMVIIDTCVRMVPGVIGNAESLKQESMEGSLEYPQYTRPASWKGMEVPEVLLTGNHGEIEKWRRNASLSITAARRPDLL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of a tRNA (guanine-N1)-methyltransferase from Anaplasma phagocytophilum bound to S-adenosylhomocysteine
rcsb
molecule tags Transferase/transferase inhibitor
source organism Anaplasma phagocytophilum
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 66
structure length 223
sequence length 223
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2012-12-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4ig6A02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4ig6A01
1X7OA 4KDZA 4J3CA 4JALA 3IEFA 3AXZA 4YQDA 4JAKA 1ZJRA 3KNUA 4YQTA 3BBDA 4CNGA 3BBHA 3L8UA 1OY5A 5GMBA 4YQNA 4YQ7A 1UALA 4MCDA 4CNEA 4E8BA 1P9PA 4YQOA 2CX8A 3DCMX 4IG6A 4YQSA 4CNDA 4X3MA 4YQBA 3OIIA 5FAIA 4CNFA 4YQCA 3AIAA 1K3RA 4X3LA 4YQRA 1J85A 3BBEA 3N4JA 3QUVA 4YVGA 4YPYA 3ILKA 3N4KA 1VHKA 4YQPA 1VH0A 4XBOA 1UAKA 3E5YA 1VHYA 3KW2A 4YQ1A 4YVIA 5GM8A 3OIJA 3OINA 1GZ0A 4YQ0A 2Z0YA 3IC6A 2I6DA 4YQ5A 3AI9X 4RG1A 2O3AA 3NK6A 4YPWA 4PZKA 4YQ9A 4YVHA 3GYQA 2V3KA 4H3ZA 1UAMA 1UAJA 4MCBA 4YQQA 3KTYA 2QWVA 4L69A 4YQLA 4YQ6A 4YQIA 4YQ4A 4YQ8A 4MCCA 3O7BA 2HA8A 4YQJA 3NK7A 1NS5A 3KY7A 4KGNA 5CO4A 1IPAA 1NXZA 4YQKA 2V3JA 1Z85A 4YPXA 4FAKA 5D9FA 1V2XA 2EGWA 1TO0A 2QMMA 4YQ2A 2EGVA 4YQAA 4YQGA 3ONPA 4YPZA 5GMCA 1MXIA 1O6DA 4H3YA 1X7PA 2YY8A 4YVJA 1V6ZA 4YVKA 4YQ3A
chains in the Genus database with same CATH superfamily
1X7OA 4KDZA 4J3CA 4JALA 3IEFA 3AXZA 4YQDA 4JAKA 1ZJRA 3KNUA 4YQTA 3BBDA 4CNGA 3BBHA 3L8UA 1OY5A 3SSXN 5GMBA 4YQNA 4YQ7A 1TROA 1UALA 4MCDA 4CNEA 4E8BA 1P9PA 4YQOA 2CX8A 4FMWA 3DCMX 4IG6A 4YQSA 4CNDA 4X3MA 4YQBA 1CO0A 3OIIA 3FRWA 5FAIA 4CNFA 4YQCA 3AIAA 4JWFA 3SSWN 4JWJA 1K3RA 1ZT9A 4X3LA 4YQRA 1J85A 3BBEA 3N4JA 3QUVA 4YVGA 2OZ9R 4YPYA 3ILKA 3N4KA 1VHKA 4YQPA 1WRPR 1VH0A 4XBOA 1WRTR 1UAKA 3E5YA 1VHYA 3KW2A 4YQ1A 4YVIA 5GM8A 3OIJA 3OINA 1GZ0A 4YQ0A 2Z0YA 3IC6A 2I6DA 4YQ5A 3AI9X 4RG1A 3G1CA 2O3AA 3NK6A 4YPWA 4PZKA 4YQ9A 4YVHA 3KORA 3GYQA 2V3KA 4H3ZA 3WRPA 1UAMA 2XDIA 1UAJA 4MCBA 4YQQA 3KTYA 2QWVA 4L69A 4YQLA 4YQ6A 4YQIA 4YQ4A 4YQ8A 4MCCA 1RCSA 3O7BA 4JWGA 2HA8A 4YQJA 3NK7A 1NS5A 3KY7A 4KGNA 5CO4A 1IPAA 1NXZA 4YQKA 1MI7R 2V3JA 1Z85A 4YPXA 4FAKA 5D9FA 1V2XA 2EGWA 1TO0A 2QMMA 4JWHA 4YQ2A 2EGVA 4YQAA 4YQGA 3ONPA 4YPZA 5GMCA 1MXIA 1O6DA 1TRRA 4H3YA 1X7PA 2YY8A 4YVJA 1V6ZA 1JHGA 1WRSR 4YVKA 4YQ3A
chains in the Genus database with same CATH topology
1X7OA 4KDZA 4J3CA 4JALA 3IEFA 3AXZA 4YQDA 4JAKA 1ZJRA 3KNUA 4YQTA 3BBDA 4CNGA 3BBHA 3L8UA 1OY5A 5GMBA 4YQNA 4YQ7A 1UALA 4MCDA 4CNEA 4E8BA 1P9PA 4YQOA 2CX8A 4FMWA 3DCMX 4IG6A 4YQSA 4CNDA 4X3MA 4YQBA 3OIIA 5FAIA 4CNFA 4YQCA 3AIAA 4JWFA 4JWJA 1K3RA 4X3LA 4YQRA 1J85A 3BBEA 3N4JA 3QUVA 4YVGA 4YPYA 3ILKA 3N4KA 1VHKA 4YQPA 1VH0A 4XBOA 1UAKA 3E5YA 1VHYA 3KW2A 4YQ1A 4YVIA 5GM8A 3OIJA 3OINA 1GZ0A 4YQ0A 2Z0YA 3IC6A 2I6DA 4YQ5A 3AI9X 4RG1A 2O3AA 3NK6A 4YPWA 4PZKA 4YQ9A 4YVHA 3GYQA 2V3KA 4H3ZA 1UAMA 1UAJA 4MCBA 4YQQA 3KTYA 2QWVA 4L69A 4YQLA 4YQ6A 4YQIA 4YQ4A 4YQ8A 4MCCA 3O7BA 4JWGA 2HA8A 4YQJA 3NK7A 1NS5A 3KY7A 4KGNA 5CO4A 1IPAA 1NXZA 4YQKA 2V3JA 1Z85A 4YPXA 4FAKA 5D9FA 1V2XA 2EGWA 1TO0A 2QMMA 4JWHA 4YQ2A 2EGVA 4YQAA 4YQGA 3ONPA 4YPZA 5GMCA 1MXIA 1O6DA 4H3YA 1X7PA 2YY8A 4YVJA 1V6ZA 4YVKA 4YQ3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1X7O A;  4KDZ A;  4J3C A;  4JAL A;  3IEF A;  3AXZ A;  4YQD A;  4JAK A;  1ZJR A;  3KNU A;  4YQT A;  3BBD A;  4CNG A;  3BBH A;  3L8U A;  1OY5 A;  5GMB A;  4YQN A;  4YQ7 A;  1UAL A;  4MCD A;  4CNE A;  4E8B A;  1P9P A;  4YQO A;  2CX8 A;  3DCM X;  4IG6 A;  4YQS A;  4CND A;  4X3M A;  4YQB A;  3OII A;  5FAI A;  4CNF A;  4YQC A;  3AIA A;  1K3R A;  4X3L A;  4YQR A;  1J85 A;  3BBE A;  3N4J A;  3QUV A;  4YVG A;  4YPY A;  3ILK A;  3N4K A;  1VHK A;  4YQP A;  1VH0 A;  4XBO A;  1UAK A;  3E5Y A;  1VHY A;  3KW2 A;  4YQ1 A;  4YVI A;  5GM8 A;  3OIJ A;  3OIN A;  1GZ0 A;  4YQ0 A;  2Z0Y A;  3IC6 A;  2I6D A;  4YQ5 A;  3AI9 X;  4RG1 A;  2O3A A;  3NK6 A;  4YPW A;  4PZK A;  4YQ9 A;  4YVH A;  3GYQ A;  2V3K A;  4H3Z A;  1UAM A;  1UAJ A;  4MCB A;  4YQQ A;  3KTY A;  2QWV A;  4L69 A;  4YQL A;  4YQ6 A;  4YQI A;  4YQ4 A;  4YQ8 A;  4MCC A;  3O7B A;  2HA8 A;  4YQJ A;  3NK7 A;  1NS5 A;  3KY7 A;  4KGN A;  5CO4 A;  1IPA A;  1NXZ A;  4YQK A;  2V3J A;  1Z85 A;  4YPX A;  4FAK A;  5D9F A;  1V2X A;  2EGW A;  1TO0 A;  2QMM A;  4YQ2 A;  2EGV A;  4YQA A;  4YQG A;  3ONP A;  4YPZ A;  5GMC A;  1MXI A;  1O6D A;  4H3Y A;  1X7P A;  2YY8 A;  4YVJ A;  1V6Z A;  4YVK A;  4YQ3 A; 
#chains in the Genus database with same CATH topology
 1X7O A;  4KDZ A;  4J3C A;  4JAL A;  3IEF A;  3AXZ A;  4YQD A;  4JAK A;  1ZJR A;  3KNU A;  4YQT A;  3BBD A;  4CNG A;  3BBH A;  3L8U A;  1OY5 A;  3SSX N;  5GMB A;  4YQN A;  4YQ7 A;  1TRO A;  1UAL A;  4MCD A;  4CNE A;  4E8B A;  1P9P A;  4YQO A;  2CX8 A;  4FMW A;  3DCM X;  4IG6 A;  4YQS A;  4CND A;  4X3M A;  4YQB A;  1CO0 A;  3OII A;  3FRW A;  5FAI A;  4CNF A;  4YQC A;  3AIA A;  4JWF A;  3SSW N;  4JWJ A;  1K3R A;  1ZT9 A;  4X3L A;  4YQR A;  1J85 A;  3BBE A;  3N4J A;  3QUV A;  4YVG A;  2OZ9 R;  4YPY A;  3ILK A;  3N4K A;  1VHK A;  4YQP A;  1WRP R;  1VH0 A;  4XBO A;  1WRT R;  1UAK A;  3E5Y A;  1VHY A;  3KW2 A;  4YQ1 A;  4YVI A;  5GM8 A;  3OIJ A;  3OIN A;  1GZ0 A;  4YQ0 A;  2Z0Y A;  3IC6 A;  2I6D A;  4YQ5 A;  3AI9 X;  4RG1 A;  3G1C A;  2O3A A;  3NK6 A;  4YPW A;  4PZK A;  4YQ9 A;  4YVH A;  3KOR A;  3GYQ A;  2V3K A;  4H3Z A;  3WRP A;  1UAM A;  2XDI A;  1UAJ A;  4MCB A;  4YQQ A;  3KTY A;  2QWV A;  4L69 A;  4YQL A;  4YQ6 A;  4YQI A;  4YQ4 A;  4YQ8 A;  4MCC A;  1RCS A;  3O7B A;  4JWG A;  2HA8 A;  4YQJ A;  3NK7 A;  1NS5 A;  3KY7 A;  4KGN A;  5CO4 A;  1IPA A;  1NXZ A;  4YQK A;  1MI7 R;  2V3J A;  1Z85 A;  4YPX A;  4FAK A;  5D9F A;  1V2X A;  2EGW A;  1TO0 A;  2QMM A;  4JWH A;  4YQ2 A;  2EGV A;  4YQA A;  4YQG A;  3ONP A;  4YPZ A;  5GMC A;  1MXI A;  1O6D A;  1TRR A;  4H3Y A;  1X7P A;  2YY8 A;  4YVJ A;  1V6Z A;  1JHG A;  1WRS R;  4YVK A;  4YQ3 A; 
#chains in the Genus database with same CATH homology
 1X7O A;  4KDZ A;  4J3C A;  4JAL A;  3IEF A;  3AXZ A;  4YQD A;  4JAK A;  1ZJR A;  3KNU A;  4YQT A;  3BBD A;  4CNG A;  3BBH A;  3L8U A;  1OY5 A;  5GMB A;  4YQN A;  4YQ7 A;  1UAL A;  4MCD A;  4CNE A;  4E8B A;  1P9P A;  4YQO A;  2CX8 A;  4FMW A;  3DCM X;  4IG6 A;  4YQS A;  4CND A;  4X3M A;  4YQB A;  3OII A;  5FAI A;  4CNF A;  4YQC A;  3AIA A;  4JWF A;  4JWJ A;  1K3R A;  4X3L A;  4YQR A;  1J85 A;  3BBE A;  3N4J A;  3QUV A;  4YVG A;  4YPY A;  3ILK A;  3N4K A;  1VHK A;  4YQP A;  1VH0 A;  4XBO A;  1UAK A;  3E5Y A;  1VHY A;  3KW2 A;  4YQ1 A;  4YVI A;  5GM8 A;  3OIJ A;  3OIN A;  1GZ0 A;  4YQ0 A;  2Z0Y A;  3IC6 A;  2I6D A;  4YQ5 A;  3AI9 X;  4RG1 A;  2O3A A;  3NK6 A;  4YPW A;  4PZK A;  4YQ9 A;  4YVH A;  3GYQ A;  2V3K A;  4H3Z A;  1UAM A;  1UAJ A;  4MCB A;  4YQQ A;  3KTY A;  2QWV A;  4L69 A;  4YQL A;  4YQ6 A;  4YQI A;  4YQ4 A;  4YQ8 A;  4MCC A;  3O7B A;  4JWG A;  2HA8 A;  4YQJ A;  3NK7 A;  1NS5 A;  3KY7 A;  4KGN A;  5CO4 A;  1IPA A;  1NXZ A;  4YQK A;  2V3J A;  1Z85 A;  4YPX A;  4FAK A;  5D9F A;  1V2X A;  2EGW A;  1TO0 A;  2QMM A;  4JWH A;  4YQ2 A;  2EGV A;  4YQA A;  4YQG A;  3ONP A;  4YPZ A;  5GMC A;  1MXI A;  1O6D A;  4H3Y A;  1X7P A;  2YY8 A;  4YVJ A;  1V6Z A;  4YVK A;  4YQ3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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