4YPXA

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 74
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
Knots found
sequence length
249
structure length
239
Chain Sequence
RGSHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGADGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 74
structure length 239
sequence length 249
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4ypxA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4ypxA01
5GM8A 3IC6A 4YQLA 1VHYA 4XBOA 1V2XA 4MCBA 1X7OA 4YVHA 5GMBA 1MXIA 4FAKA 1P9PA 4CNEA 3L8UA 4YPWA 4YQ9A 5FAIA 4MCDA 2EGWA 2EGVA 3KW2A 3O7BA 3N4JA 3OIIA 4YVKA 4CNDA 3AI9X 4YQ0A 2YY8A 4YQCA 4YQ5A 4YQ7A 4YQNA 4YPXA 3N4KA 2HA8A 1VHKA 2Z0YA 4YPYA 4J3CA 4X3LA 3KY7A 4YQKA 4YQOA 1TO0A 4YQGA 3OINA 3NK6A 1OY5A 4CNGA 4YQJA 1UAKA 4YQ6A 4YQ2A 4YQPA 4YQRA 3IEFA 5GMCA 1VH0A 4KGNA 2V3JA 1GZ0A 4YQTA 1O6DA 3DCMX 1Z85A 4L69A 4RG1A 3QUVA 1UAJA 4KDZA 3AXZA 4YQ1A 4YQ4A 4YVIA 1X7PA 1UAMA 4YVJA 4CNFA 3ILKA 3AIAA 4YQDA 3BBDA 4MCCA 3BBHA 3KTYA 4H3YA 4YVGA 2O3AA 4JALA 4JAKA 3ONPA 3BBEA 4YQAA 4YQ8A 4YPZA 3OIJA 3KNUA 2V3KA 4YQSA 4YQIA 4YQ3A 1ZJRA 4IG6A 1K3RA 1J85A 2I6DA 1IPAA 4YQBA 3GYQA 4PZKA 5CO4A 3NK7A 1UALA 4YQQA 5D9FA 3E5YA 2QWVA 4X3MA 4E8BA 2QMMA 4H3ZA 2CX8A 1V6ZA 1NS5A 1NXZA
chains in the Genus database with same CATH superfamily
5GM8A 2OZ9R 3IC6A 4YQLA 1VHYA 4XBOA 1V2XA 1RCSA 4MCBA 1X7OA 4YVHA 5GMBA 1MXIA 4FAKA 1P9PA 4CNEA 3SSWN 3L8UA 3WRPA 4YPWA 4YQ9A 5FAIA 4MCDA 2EGWA 2EGVA 3KW2A 3O7BA 3N4JA 3OIIA 4YVKA 4CNDA 3AI9X 4YQ0A 2YY8A 4YQCA 4YQ5A 4YQ7A 4YQNA 4YPXA 3N4KA 1WRPR 2HA8A 1VHKA 2Z0YA 4YPYA 1CO0A 4J3CA 4X3LA 3KY7A 1WRSR 4YQKA 4JWHA 4YQOA 1TO0A 4JWGA 4YQGA 3OINA 3NK6A 1OY5A 4CNGA 4YQJA 3G1CA 3SSXN 1UAKA 4YQ6A 4JWFA 4YQ2A 1TROA 4YQPA 4YQRA 3IEFA 5GMCA 1VH0A 4KGNA 2V3JA 1GZ0A 4YQTA 1O6DA 3DCMX 1Z85A 4L69A 4RG1A 3QUVA 1UAJA 4KDZA 3AXZA 4YQ1A 4YQ4A 4YVIA 4JWJA 1X7PA 1UAMA 4YVJA 4CNFA 3ILKA 3AIAA 4YQDA 3BBDA 1MI7R 4MCCA 3BBHA 3KTYA 1JHGA 3FRWA 4H3YA 4YVGA 2O3AA 4JALA 4JAKA 2XDIA 3ONPA 3BBEA 1TRRA 4YQAA 4YQ8A 4YPZA 3OIJA 3KNUA 2V3KA 4YQSA 4YQIA 4YQ3A 1ZJRA 4IG6A 1K3RA 1J85A 2I6DA 1IPAA 4YQBA 3GYQA 4PZKA 5CO4A 4FMWA 3NK7A 1UALA 4YQQA 5D9FA 3E5YA 2QWVA 1ZT9A 4X3MA 3KORA 4E8BA 2QMMA 4H3ZA 2CX8A 1V6ZA 1NS5A 1NXZA 1WRTR
chains in the Genus database with same CATH topology
5GM8A 3IC6A 4YQLA 1VHYA 4XBOA 1V2XA 4MCBA 1X7OA 4YVHA 5GMBA 1MXIA 4FAKA 1P9PA 4CNEA 3L8UA 4YPWA 4YQ9A 5FAIA 4MCDA 2EGWA 2EGVA 3KW2A 3O7BA 3N4JA 3OIIA 4YVKA 4CNDA 3AI9X 4YQ0A 2YY8A 4YQCA 4YQ5A 4YQ7A 4YQNA 4YPXA 3N4KA 2HA8A 1VHKA 2Z0YA 4YPYA 4J3CA 4X3LA 3KY7A 4YQKA 4JWHA 4YQOA 1TO0A 4JWGA 4YQGA 3OINA 3NK6A 1OY5A 4CNGA 4YQJA 1UAKA 4YQ6A 4JWFA 4YQ2A 4YQPA 4YQRA 3IEFA 5GMCA 1VH0A 4KGNA 2V3JA 1GZ0A 4YQTA 1O6DA 3DCMX 1Z85A 4L69A 4RG1A 3QUVA 1UAJA 4KDZA 3AXZA 4YQ1A 4YQ4A 4YVIA 4JWJA 1X7PA 1UAMA 4YVJA 4CNFA 3ILKA 3AIAA 4YQDA 3BBDA 4MCCA 3BBHA 3KTYA 4H3YA 4YVGA 2O3AA 4JALA 4JAKA 3ONPA 3BBEA 4YQAA 4YQ8A 4YPZA 3OIJA 3KNUA 2V3KA 4YQSA 4YQIA 4YQ3A 1ZJRA 4IG6A 1K3RA 1J85A 2I6DA 1IPAA 4YQBA 3GYQA 4PZKA 5CO4A 4FMWA 3NK7A 1UALA 4YQQA 5D9FA 3E5YA 2QWVA 4X3MA 4E8BA 2QMMA 4H3ZA 2CX8A 1V6ZA 1NS5A 1NXZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5GM8 A;  3IC6 A;  4YQL A;  1VHY A;  4XBO A;  1V2X A;  4MCB A;  1X7O A;  4YVH A;  5GMB A;  1MXI A;  4FAK A;  1P9P A;  4CNE A;  3L8U A;  4YPW A;  4YQ9 A;  5FAI A;  4MCD A;  2EGW A;  2EGV A;  3KW2 A;  3O7B A;  3N4J A;  3OII A;  4YVK A;  4CND A;  3AI9 X;  4YQ0 A;  2YY8 A;  4YQC A;  4YQ5 A;  4YQ7 A;  4YQN A;  4YPX A;  3N4K A;  2HA8 A;  1VHK A;  2Z0Y A;  4YPY A;  4J3C A;  4X3L A;  3KY7 A;  4YQK A;  4YQO A;  1TO0 A;  4YQG A;  3OIN A;  3NK6 A;  1OY5 A;  4CNG A;  4YQJ A;  1UAK A;  4YQ6 A;  4YQ2 A;  4YQP A;  4YQR A;  3IEF A;  5GMC A;  1VH0 A;  4KGN A;  2V3J A;  1GZ0 A;  4YQT A;  1O6D A;  3DCM X;  1Z85 A;  4L69 A;  4RG1 A;  3QUV A;  1UAJ A;  4KDZ A;  3AXZ A;  4YQ1 A;  4YQ4 A;  4YVI A;  1X7P A;  1UAM A;  4YVJ A;  4CNF A;  3ILK A;  3AIA A;  4YQD A;  3BBD A;  4MCC A;  3BBH A;  3KTY A;  4H3Y A;  4YVG A;  2O3A A;  4JAL A;  4JAK A;  3ONP A;  3BBE A;  4YQA A;  4YQ8 A;  4YPZ A;  3OIJ A;  3KNU A;  2V3K A;  4YQS A;  4YQI A;  4YQ3 A;  1ZJR A;  4IG6 A;  1K3R A;  1J85 A;  2I6D A;  1IPA A;  4YQB A;  3GYQ A;  4PZK A;  5CO4 A;  3NK7 A;  1UAL A;  4YQQ A;  5D9F A;  3E5Y A;  2QWV A;  4X3M A;  4E8B A;  2QMM A;  4H3Z A;  2CX8 A;  1V6Z A;  1NS5 A;  1NXZ A; 
#chains in the Genus database with same CATH topology
 5GM8 A;  2OZ9 R;  3IC6 A;  4YQL A;  1VHY A;  4XBO A;  1V2X A;  1RCS A;  4MCB A;  1X7O A;  4YVH A;  5GMB A;  1MXI A;  4FAK A;  1P9P A;  4CNE A;  3SSW N;  3L8U A;  3WRP A;  4YPW A;  4YQ9 A;  5FAI A;  4MCD A;  2EGW A;  2EGV A;  3KW2 A;  3O7B A;  3N4J A;  3OII A;  4YVK A;  4CND A;  3AI9 X;  4YQ0 A;  2YY8 A;  4YQC A;  4YQ5 A;  4YQ7 A;  4YQN A;  4YPX A;  3N4K A;  1WRP R;  2HA8 A;  1VHK A;  2Z0Y A;  4YPY A;  1CO0 A;  4J3C A;  4X3L A;  3KY7 A;  1WRS R;  4YQK A;  4JWH A;  4YQO A;  1TO0 A;  4JWG A;  4YQG A;  3OIN A;  3NK6 A;  1OY5 A;  4CNG A;  4YQJ A;  3G1C A;  3SSX N;  1UAK A;  4YQ6 A;  4JWF A;  4YQ2 A;  1TRO A;  4YQP A;  4YQR A;  3IEF A;  5GMC A;  1VH0 A;  4KGN A;  2V3J A;  1GZ0 A;  4YQT A;  1O6D A;  3DCM X;  1Z85 A;  4L69 A;  4RG1 A;  3QUV A;  1UAJ A;  4KDZ A;  3AXZ A;  4YQ1 A;  4YQ4 A;  4YVI A;  4JWJ A;  1X7P A;  1UAM A;  4YVJ A;  4CNF A;  3ILK A;  3AIA A;  4YQD A;  3BBD A;  1MI7 R;  4MCC A;  3BBH A;  3KTY A;  1JHG A;  3FRW A;  4H3Y A;  4YVG A;  2O3A A;  4JAL A;  4JAK A;  2XDI A;  3ONP A;  3BBE A;  1TRR A;  4YQA A;  4YQ8 A;  4YPZ A;  3OIJ A;  3KNU A;  2V3K A;  4YQS A;  4YQI A;  4YQ3 A;  1ZJR A;  4IG6 A;  1K3R A;  1J85 A;  2I6D A;  1IPA A;  4YQB A;  3GYQ A;  4PZK A;  5CO4 A;  4FMW A;  3NK7 A;  1UAL A;  4YQQ A;  5D9F A;  3E5Y A;  2QWV A;  1ZT9 A;  4X3M A;  3KOR A;  4E8B A;  2QMM A;  4H3Z A;  2CX8 A;  1V6Z A;  1NS5 A;  1NXZ A;  1WRT R; 
#chains in the Genus database with same CATH homology
 5GM8 A;  3IC6 A;  4YQL A;  1VHY A;  4XBO A;  1V2X A;  4MCB A;  1X7O A;  4YVH A;  5GMB A;  1MXI A;  4FAK A;  1P9P A;  4CNE A;  3L8U A;  4YPW A;  4YQ9 A;  5FAI A;  4MCD A;  2EGW A;  2EGV A;  3KW2 A;  3O7B A;  3N4J A;  3OII A;  4YVK A;  4CND A;  3AI9 X;  4YQ0 A;  2YY8 A;  4YQC A;  4YQ5 A;  4YQ7 A;  4YQN A;  4YPX A;  3N4K A;  2HA8 A;  1VHK A;  2Z0Y A;  4YPY A;  4J3C A;  4X3L A;  3KY7 A;  4YQK A;  4JWH A;  4YQO A;  1TO0 A;  4JWG A;  4YQG A;  3OIN A;  3NK6 A;  1OY5 A;  4CNG A;  4YQJ A;  1UAK A;  4YQ6 A;  4JWF A;  4YQ2 A;  4YQP A;  4YQR A;  3IEF A;  5GMC A;  1VH0 A;  4KGN A;  2V3J A;  1GZ0 A;  4YQT A;  1O6D A;  3DCM X;  1Z85 A;  4L69 A;  4RG1 A;  3QUV A;  1UAJ A;  4KDZ A;  3AXZ A;  4YQ1 A;  4YQ4 A;  4YVI A;  4JWJ A;  1X7P A;  1UAM A;  4YVJ A;  4CNF A;  3ILK A;  3AIA A;  4YQD A;  3BBD A;  4MCC A;  3BBH A;  3KTY A;  4H3Y A;  4YVG A;  2O3A A;  4JAL A;  4JAK A;  3ONP A;  3BBE A;  4YQA A;  4YQ8 A;  4YPZ A;  3OIJ A;  3KNU A;  2V3K A;  4YQS A;  4YQI A;  4YQ3 A;  1ZJR A;  4IG6 A;  1K3R A;  1J85 A;  2I6D A;  1IPA A;  4YQB A;  3GYQ A;  4PZK A;  5CO4 A;  4FMW A;  3NK7 A;  1UAL A;  4YQQ A;  5D9F A;  3E5Y A;  2QWV A;  4X3M A;  4E8B A;  2QMM A;  4H3Z A;  2CX8 A;  1V6Z A;  1NS5 A;  1NXZ A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...