4YQDA

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
Knots found
sequence length
249
structure length
244
Chain Sequence
GSHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGASASFADGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 70
structure length 244
sequence length 249
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yqdA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yqdA01
4YPWA 4L69A 3KY7A 3BBEA 4IG6A 3OIIA 3AIAA 3KW2A 4YPYA 3IEFA 4YQ6A 4YPXA 4YQ4A 3BBHA 4YQ9A 4CNDA 3QUVA 1UAKA 3KNUA 4YQGA 4CNGA 2CX8A 1VHYA 2V3KA 1UAJA 4MCCA 3IC6A 4YQKA 2EGWA 3KTYA 4MCDA 2QWVA 1TO0A 4YQSA 3OIJA 1V2XA 4YQ2A 1UAMA 1NXZA 4KGNA 4CNEA 1J85A 4YQ1A 4YQJA 4YQOA 1X7PA 4X3LA 4YQLA 4YVJA 4MCBA 4YQAA 4FAKA 2I6DA 1V6ZA 4YVGA 3ONPA 4YQ7A 1NS5A 4E8BA 4YQ0A 3N4KA 1Z85A 4YVKA 2O3AA 1ZJRA 4YQ3A 4H3ZA 4X3MA 3NK6A 1P9PA 3ILKA 3L8UA 3DCMX 4YQIA 3N4JA 5FAIA 4YQ5A 2V3JA 4YQ8A 4KDZA 5GM8A 4XBOA 4YQPA 4YQBA 4YQCA 4YQTA 4J3CA 4YQNA 4YVHA 1MXIA 1X7OA 4YQDA 4YQQA 5GMCA 1VH0A 3O7BA 1UALA 3GYQA 4CNFA 5D9FA 3AXZA 4JAKA 2QMMA 2HA8A 4YVIA 4JALA 3AI9X 1GZ0A 1VHKA 3BBDA 2EGVA 1O6DA 5CO4A 1OY5A 4H3YA 2Z0YA 4YPZA 3E5YA 1K3RA 1IPAA 4PZKA 4RG1A 3NK7A 3OINA 2YY8A 5GMBA 4YQRA
chains in the Genus database with same CATH superfamily
4YPWA 4L69A 3KY7A 3BBEA 4IG6A 3OIIA 3AIAA 3KW2A 4YPYA 3IEFA 4YQ6A 4YPXA 4YQ4A 3BBHA 4YQ9A 3SSXN 4CNDA 3QUVA 1UAKA 3KNUA 4YQGA 4CNGA 1JHGA 2CX8A 1VHYA 2V3KA 3G1CA 1UAJA 1ZT9A 4MCCA 1WRTR 3IC6A 4YQKA 2EGWA 3KTYA 4MCDA 2QWVA 1TO0A 4YQSA 1WRPR 3OIJA 1V2XA 4YQ2A 3KORA 1UAMA 1NXZA 4KGNA 4CNEA 1J85A 4YQ1A 4YQJA 4YQOA 1X7PA 4X3LA 4YQLA 4YVJA 4MCBA 4YQAA 4JWJA 4FAKA 2I6DA 1V6ZA 4YVGA 3ONPA 4YQ7A 1NS5A 4E8BA 4YQ0A 3N4KA 1Z85A 1TRRA 4YVKA 3FRWA 2O3AA 2OZ9R 1ZJRA 4JWFA 4YQ3A 4H3ZA 4X3MA 1MI7R 3NK6A 1P9PA 3ILKA 3L8UA 3DCMX 4YQIA 3N4JA 5FAIA 4YQ5A 2V3JA 4YQ8A 4KDZA 5GM8A 2XDIA 4XBOA 4YQPA 4YQBA 4YQCA 3WRPA 4YQTA 4J3CA 4YQNA 4FMWA 4YVHA 1MXIA 1X7OA 3SSWN 4YQDA 4YQQA 5GMCA 1VH0A 3O7BA 1UALA 3GYQA 4CNFA 5D9FA 3AXZA 4JAKA 2QMMA 5GMBA 2HA8A 4YVIA 4JALA 3AI9X 1GZ0A 1CO0A 1RCSA 1VHKA 3BBDA 2EGVA 1O6DA 5CO4A 1OY5A 4H3YA 2Z0YA 4JWGA 4YPZA 3E5YA 1K3RA 1IPAA 4PZKA 4RG1A 3NK7A 1WRSR 1TROA 3OINA 2YY8A 4JWHA 4YQRA
chains in the Genus database with same CATH topology
4YPWA 4L69A 3KY7A 3BBEA 4IG6A 3OIIA 3AIAA 3KW2A 4YPYA 3IEFA 4YQ6A 4YPXA 4YQ4A 3BBHA 4YQ9A 4CNDA 3QUVA 1UAKA 3KNUA 4YQGA 4CNGA 2CX8A 1VHYA 2V3KA 1UAJA 4MCCA 3IC6A 4YQKA 2EGWA 3KTYA 4MCDA 2QWVA 1TO0A 4YQSA 3OIJA 1V2XA 4YQ2A 1UAMA 1NXZA 4KGNA 4CNEA 1J85A 4YQ1A 4YQJA 4YQOA 1X7PA 4X3LA 4YQLA 4YVJA 4MCBA 4YQAA 4JWJA 4FAKA 2I6DA 1V6ZA 4YVGA 3ONPA 4YQ7A 1NS5A 4E8BA 4YQ0A 3N4KA 1Z85A 4YVKA 2O3AA 1ZJRA 4JWFA 4YQ3A 4H3ZA 4X3MA 3NK6A 1P9PA 3ILKA 3L8UA 3DCMX 4YQIA 3N4JA 5FAIA 4YQ5A 2V3JA 4YQ8A 4KDZA 5GM8A 4XBOA 4YQPA 4YQBA 4YQCA 4YQTA 4J3CA 4YQNA 4FMWA 4YVHA 1MXIA 1X7OA 4YQDA 4YQQA 5GMCA 1VH0A 3O7BA 1UALA 3GYQA 4CNFA 5D9FA 3AXZA 4JAKA 2QMMA 5GMBA 2HA8A 4YVIA 4JALA 3AI9X 1GZ0A 1VHKA 3BBDA 2EGVA 1O6DA 5CO4A 1OY5A 4H3YA 2Z0YA 4JWGA 4YPZA 3E5YA 1K3RA 1IPAA 4PZKA 4RG1A 3NK7A 3OINA 2YY8A 4JWHA 4YQRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YPW A;  4L69 A;  3KY7 A;  3BBE A;  4IG6 A;  3OII A;  3AIA A;  3KW2 A;  4YPY A;  3IEF A;  4YQ6 A;  4YPX A;  4YQ4 A;  3BBH A;  4YQ9 A;  4CND A;  3QUV A;  1UAK A;  3KNU A;  4YQG A;  4CNG A;  2CX8 A;  1VHY A;  2V3K A;  1UAJ A;  4MCC A;  3IC6 A;  4YQK A;  2EGW A;  3KTY A;  4MCD A;  2QWV A;  1TO0 A;  4YQS A;  3OIJ A;  1V2X A;  4YQ2 A;  1UAM A;  1NXZ A;  4KGN A;  4CNE A;  1J85 A;  4YQ1 A;  4YQJ A;  4YQO A;  1X7P A;  4X3L A;  4YQL A;  4YVJ A;  4MCB A;  4YQA A;  4FAK A;  2I6D A;  1V6Z A;  4YVG A;  3ONP A;  4YQ7 A;  1NS5 A;  4E8B A;  4YQ0 A;  3N4K A;  1Z85 A;  4YVK A;  2O3A A;  1ZJR A;  4YQ3 A;  4H3Z A;  4X3M A;  3NK6 A;  1P9P A;  3ILK A;  3L8U A;  3DCM X;  4YQI A;  3N4J A;  5FAI A;  4YQ5 A;  2V3J A;  4YQ8 A;  4KDZ A;  5GM8 A;  4XBO A;  4YQP A;  4YQB A;  4YQC A;  4YQT A;  4J3C A;  4YQN A;  4YVH A;  1MXI A;  1X7O A;  4YQD A;  4YQQ A;  5GMC A;  1VH0 A;  3O7B A;  1UAL A;  3GYQ A;  4CNF A;  5D9F A;  3AXZ A;  4JAK A;  2QMM A;  2HA8 A;  4YVI A;  4JAL A;  3AI9 X;  1GZ0 A;  1VHK A;  3BBD A;  2EGV A;  1O6D A;  5CO4 A;  1OY5 A;  4H3Y A;  2Z0Y A;  4YPZ A;  3E5Y A;  1K3R A;  1IPA A;  4PZK A;  4RG1 A;  3NK7 A;  3OIN A;  2YY8 A;  5GMB A;  4YQR A; 
#chains in the Genus database with same CATH topology
 4YPW A;  4L69 A;  3KY7 A;  3BBE A;  4IG6 A;  3OII A;  3AIA A;  3KW2 A;  4YPY A;  3IEF A;  4YQ6 A;  4YPX A;  4YQ4 A;  3BBH A;  4YQ9 A;  3SSX N;  4CND A;  3QUV A;  1UAK A;  3KNU A;  4YQG A;  4CNG A;  1JHG A;  2CX8 A;  1VHY A;  2V3K A;  3G1C A;  1UAJ A;  1ZT9 A;  4MCC A;  1WRT R;  3IC6 A;  4YQK A;  2EGW A;  3KTY A;  4MCD A;  2QWV A;  1TO0 A;  4YQS A;  1WRP R;  3OIJ A;  1V2X A;  4YQ2 A;  3KOR A;  1UAM A;  1NXZ A;  4KGN A;  4CNE A;  1J85 A;  4YQ1 A;  4YQJ A;  4YQO A;  1X7P A;  4X3L A;  4YQL A;  4YVJ A;  4MCB A;  4YQA A;  4JWJ A;  4FAK A;  2I6D A;  1V6Z A;  4YVG A;  3ONP A;  4YQ7 A;  1NS5 A;  4E8B A;  4YQ0 A;  3N4K A;  1Z85 A;  1TRR A;  4YVK A;  3FRW A;  2O3A A;  2OZ9 R;  1ZJR A;  4JWF A;  4YQ3 A;  4H3Z A;  4X3M A;  1MI7 R;  3NK6 A;  1P9P A;  3ILK A;  3L8U A;  3DCM X;  4YQI A;  3N4J A;  5FAI A;  4YQ5 A;  2V3J A;  4YQ8 A;  4KDZ A;  5GM8 A;  2XDI A;  4XBO A;  4YQP A;  4YQB A;  4YQC A;  3WRP A;  4YQT A;  4J3C A;  4YQN A;  4FMW A;  4YVH A;  1MXI A;  1X7O A;  3SSW N;  4YQD A;  4YQQ A;  5GMC A;  1VH0 A;  3O7B A;  1UAL A;  3GYQ A;  4CNF A;  5D9F A;  3AXZ A;  4JAK A;  2QMM A;  5GMB A;  2HA8 A;  4YVI A;  4JAL A;  3AI9 X;  1GZ0 A;  1CO0 A;  1RCS A;  1VHK A;  3BBD A;  2EGV A;  1O6D A;  5CO4 A;  1OY5 A;  4H3Y A;  2Z0Y A;  4JWG A;  4YPZ A;  3E5Y A;  1K3R A;  1IPA A;  4PZK A;  4RG1 A;  3NK7 A;  1WRS R;  1TRO A;  3OIN A;  2YY8 A;  4JWH A;  4YQR A; 
#chains in the Genus database with same CATH homology
 4YPW A;  4L69 A;  3KY7 A;  3BBE A;  4IG6 A;  3OII A;  3AIA A;  3KW2 A;  4YPY A;  3IEF A;  4YQ6 A;  4YPX A;  4YQ4 A;  3BBH A;  4YQ9 A;  4CND A;  3QUV A;  1UAK A;  3KNU A;  4YQG A;  4CNG A;  2CX8 A;  1VHY A;  2V3K A;  1UAJ A;  4MCC A;  3IC6 A;  4YQK A;  2EGW A;  3KTY A;  4MCD A;  2QWV A;  1TO0 A;  4YQS A;  3OIJ A;  1V2X A;  4YQ2 A;  1UAM A;  1NXZ A;  4KGN A;  4CNE A;  1J85 A;  4YQ1 A;  4YQJ A;  4YQO A;  1X7P A;  4X3L A;  4YQL A;  4YVJ A;  4MCB A;  4YQA A;  4JWJ A;  4FAK A;  2I6D A;  1V6Z A;  4YVG A;  3ONP A;  4YQ7 A;  1NS5 A;  4E8B A;  4YQ0 A;  3N4K A;  1Z85 A;  4YVK A;  2O3A A;  1ZJR A;  4JWF A;  4YQ3 A;  4H3Z A;  4X3M A;  3NK6 A;  1P9P A;  3ILK A;  3L8U A;  3DCM X;  4YQI A;  3N4J A;  5FAI A;  4YQ5 A;  2V3J A;  4YQ8 A;  4KDZ A;  5GM8 A;  4XBO A;  4YQP A;  4YQB A;  4YQC A;  4YQT A;  4J3C A;  4YQN A;  4FMW A;  4YVH A;  1MXI A;  1X7O A;  4YQD A;  4YQQ A;  5GMC A;  1VH0 A;  3O7B A;  1UAL A;  3GYQ A;  4CNF A;  5D9F A;  3AXZ A;  4JAK A;  2QMM A;  5GMB A;  2HA8 A;  4YVI A;  4JAL A;  3AI9 X;  1GZ0 A;  1VHK A;  3BBD A;  2EGV A;  1O6D A;  5CO4 A;  1OY5 A;  4H3Y A;  2Z0Y A;  4JWG A;  4YPZ A;  3E5Y A;  1K3R A;  1IPA A;  4PZK A;  4RG1 A;  3NK7 A;  3OIN A;  2YY8 A;  4JWH A;  4YQR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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