4YQTA

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
Knots found
sequence length
248
structure length
237
Chain Sequence
SHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGDGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 71
structure length 237
sequence length 248
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yqtA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yqtA01
4H3ZA 1NXZA 4YQ3A 2CX8A 1P9PA 4CNDA 3AI9X 3KY7A 4YQLA 3ILKA 3KTYA 4YQSA 4J3CA 4YQ4A 4YVKA 4YVIA 4YQ5A 3AIAA 1X7PA 4YQRA 4H3YA 2QWVA 1K3RA 4YPWA 4MCBA 4E8BA 4X3LA 4YQOA 3ONPA 4YQAA 2EGVA 4YQDA 1MXIA 4YQ8A 4YQ9A 1X7OA 4YQ1A 4IG6A 3IC6A 1IPAA 1O6DA 4L69A 5GMBA 4YVGA 4YVJA 1VHKA 4YPZA 2V3KA 3E5YA 1Z85A 5GM8A 2V3JA 1V6ZA 5GMCA 4YQGA 5D9FA 4YQJA 4YPXA 3OIJA 3BBDA 1OY5A 4YQ2A 3IEFA 4KGNA 2HA8A 4PZKA 4YQCA 3AXZA 4YQ7A 1UALA 4CNEA 3KNUA 3NK7A 3N4JA 3DCMX 3QUVA 4KDZA 1J85A 4YQ0A 1VH0A 1UAKA 2QMMA 4RG1A 3L8UA 1VHYA 5FAIA 2I6DA 3BBHA 4FAKA 5CO4A 3O7BA 4MCDA 4YQPA 4YQBA 4JALA 3OIIA 3NK6A 2EGWA 3GYQA 3BBEA 3N4KA 1GZ0A 2O3AA 4JAKA 3OINA 2Z0YA 4YQKA 4YQTA 3KW2A 4YVHA 4MCCA 4YPYA 1ZJRA 4CNGA 1NS5A 2YY8A 4YQNA 4YQIA 4CNFA 1UAJA 4XBOA 1UAMA 4YQQA 1V2XA 4X3MA 1TO0A 4YQ6A
chains in the Genus database with same CATH superfamily
4H3ZA 1NXZA 4YQ3A 2CX8A 1P9PA 4CNDA 3AI9X 3KY7A 4YQLA 3ILKA 3KTYA 4FMWA 4YQSA 1ZT9A 4J3CA 4YQ4A 4YVKA 1MI7R 4YVIA 4YQ5A 3AIAA 4JWGA 1X7PA 4YQRA 4H3YA 2QWVA 1RCSA 1TROA 1K3RA 4YPWA 3G1CA 4MCBA 4E8BA 4X3LA 4YQOA 3ONPA 4YQAA 2EGVA 4YQDA 1MXIA 4YQ8A 4YQ9A 1X7OA 4YQ1A 3SSXN 4IG6A 3IC6A 1IPAA 1O6DA 4L69A 5GMBA 4YVGA 4YVJA 1VHKA 4YPZA 2V3KA 3E5YA 1Z85A 5GM8A 2V3JA 1V6ZA 5GMCA 1WRSR 4YQGA 2XDIA 5D9FA 4YQJA 4YPXA 3FRWA 4JWFA 3OIJA 3BBDA 1OY5A 4YQ2A 3IEFA 4KGNA 2HA8A 3WRPA 4PZKA 4YQCA 3AXZA 4YQ7A 1UALA 3KORA 4CNEA 3KNUA 3NK7A 3N4JA 3DCMX 3QUVA 4KDZA 1J85A 3SSWN 1WRPR 4YQ0A 1VH0A 2OZ9R 1UAKA 2QMMA 4RG1A 3L8UA 1VHYA 4JWJA 5FAIA 2I6DA 3BBHA 4FAKA 5CO4A 3O7BA 4MCDA 4YQPA 4YQBA 4JALA 3OIIA 3NK6A 2EGWA 1TRRA 3GYQA 3BBEA 3N4KA 1GZ0A 2O3AA 4JAKA 3OINA 2Z0YA 4YQKA 4YQTA 3KW2A 4YVHA 4MCCA 4YPYA 1ZJRA 1WRTR 4CNGA 1NS5A 2YY8A 4YQNA 4YQIA 4CNFA 1UAJA 4XBOA 1UAMA 1JHGA 4YQQA 1V2XA 4X3MA 1CO0A 4JWHA 1TO0A 4YQ6A
chains in the Genus database with same CATH topology
4H3ZA 1NXZA 4YQ3A 2CX8A 1P9PA 4CNDA 3AI9X 3KY7A 4YQLA 3ILKA 3KTYA 4FMWA 4YQSA 4J3CA 4YQ4A 4YVKA 4YVIA 4YQ5A 3AIAA 4JWGA 1X7PA 4YQRA 4H3YA 2QWVA 1K3RA 4YPWA 4MCBA 4E8BA 4X3LA 4YQOA 3ONPA 4YQAA 2EGVA 4YQDA 1MXIA 4YQ8A 4YQ9A 1X7OA 4YQ1A 4IG6A 3IC6A 1IPAA 1O6DA 4L69A 5GMBA 4YVGA 4YVJA 1VHKA 4YPZA 2V3KA 3E5YA 1Z85A 5GM8A 2V3JA 1V6ZA 5GMCA 4YQGA 5D9FA 4YQJA 4YPXA 4JWFA 3OIJA 3BBDA 1OY5A 4YQ2A 3IEFA 4KGNA 2HA8A 4PZKA 4YQCA 3AXZA 4YQ7A 1UALA 4CNEA 3KNUA 3NK7A 3N4JA 3DCMX 3QUVA 4KDZA 1J85A 4YQ0A 1VH0A 1UAKA 2QMMA 4RG1A 3L8UA 1VHYA 4JWJA 5FAIA 2I6DA 3BBHA 4FAKA 5CO4A 3O7BA 4MCDA 4YQPA 4YQBA 4JALA 3OIIA 3NK6A 2EGWA 3GYQA 3BBEA 3N4KA 1GZ0A 2O3AA 4JAKA 3OINA 2Z0YA 4YQKA 4YQTA 3KW2A 4YVHA 4MCCA 4YPYA 1ZJRA 4CNGA 1NS5A 2YY8A 4YQNA 4YQIA 4CNFA 1UAJA 4XBOA 1UAMA 4YQQA 1V2XA 4X3MA 4JWHA 1TO0A 4YQ6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4H3Z A;  1NXZ A;  4YQ3 A;  2CX8 A;  1P9P A;  4CND A;  3AI9 X;  3KY7 A;  4YQL A;  3ILK A;  3KTY A;  4YQS A;  4J3C A;  4YQ4 A;  4YVK A;  4YVI A;  4YQ5 A;  3AIA A;  1X7P A;  4YQR A;  4H3Y A;  2QWV A;  1K3R A;  4YPW A;  4MCB A;  4E8B A;  4X3L A;  4YQO A;  3ONP A;  4YQA A;  2EGV A;  4YQD A;  1MXI A;  4YQ8 A;  4YQ9 A;  1X7O A;  4YQ1 A;  4IG6 A;  3IC6 A;  1IPA A;  1O6D A;  4L69 A;  5GMB A;  4YVG A;  4YVJ A;  1VHK A;  4YPZ A;  2V3K A;  3E5Y A;  1Z85 A;  5GM8 A;  2V3J A;  1V6Z A;  5GMC A;  4YQG A;  5D9F A;  4YQJ A;  4YPX A;  3OIJ A;  3BBD A;  1OY5 A;  4YQ2 A;  3IEF A;  4KGN A;  2HA8 A;  4PZK A;  4YQC A;  3AXZ A;  4YQ7 A;  1UAL A;  4CNE A;  3KNU A;  3NK7 A;  3N4J A;  3DCM X;  3QUV A;  4KDZ A;  1J85 A;  4YQ0 A;  1VH0 A;  1UAK A;  2QMM A;  4RG1 A;  3L8U A;  1VHY A;  5FAI A;  2I6D A;  3BBH A;  4FAK A;  5CO4 A;  3O7B A;  4MCD A;  4YQP A;  4YQB A;  4JAL A;  3OII A;  3NK6 A;  2EGW A;  3GYQ A;  3BBE A;  3N4K A;  1GZ0 A;  2O3A A;  4JAK A;  3OIN A;  2Z0Y A;  4YQK A;  4YQT A;  3KW2 A;  4YVH A;  4MCC A;  4YPY A;  1ZJR A;  4CNG A;  1NS5 A;  2YY8 A;  4YQN A;  4YQI A;  4CNF A;  1UAJ A;  4XBO A;  1UAM A;  4YQQ A;  1V2X A;  4X3M A;  1TO0 A;  4YQ6 A; 
#chains in the Genus database with same CATH topology
 4H3Z A;  1NXZ A;  4YQ3 A;  2CX8 A;  1P9P A;  4CND A;  3AI9 X;  3KY7 A;  4YQL A;  3ILK A;  3KTY A;  4FMW A;  4YQS A;  1ZT9 A;  4J3C A;  4YQ4 A;  4YVK A;  1MI7 R;  4YVI A;  4YQ5 A;  3AIA A;  4JWG A;  1X7P A;  4YQR A;  4H3Y A;  2QWV A;  1RCS A;  1TRO A;  1K3R A;  4YPW A;  3G1C A;  4MCB A;  4E8B A;  4X3L A;  4YQO A;  3ONP A;  4YQA A;  2EGV A;  4YQD A;  1MXI A;  4YQ8 A;  4YQ9 A;  1X7O A;  4YQ1 A;  3SSX N;  4IG6 A;  3IC6 A;  1IPA A;  1O6D A;  4L69 A;  5GMB A;  4YVG A;  4YVJ A;  1VHK A;  4YPZ A;  2V3K A;  3E5Y A;  1Z85 A;  5GM8 A;  2V3J A;  1V6Z A;  5GMC A;  1WRS R;  4YQG A;  2XDI A;  5D9F A;  4YQJ A;  4YPX A;  3FRW A;  4JWF A;  3OIJ A;  3BBD A;  1OY5 A;  4YQ2 A;  3IEF A;  4KGN A;  2HA8 A;  3WRP A;  4PZK A;  4YQC A;  3AXZ A;  4YQ7 A;  1UAL A;  3KOR A;  4CNE A;  3KNU A;  3NK7 A;  3N4J A;  3DCM X;  3QUV A;  4KDZ A;  1J85 A;  3SSW N;  1WRP R;  4YQ0 A;  1VH0 A;  2OZ9 R;  1UAK A;  2QMM A;  4RG1 A;  3L8U A;  1VHY A;  4JWJ A;  5FAI A;  2I6D A;  3BBH A;  4FAK A;  5CO4 A;  3O7B A;  4MCD A;  4YQP A;  4YQB A;  4JAL A;  3OII A;  3NK6 A;  2EGW A;  1TRR A;  3GYQ A;  3BBE A;  3N4K A;  1GZ0 A;  2O3A A;  4JAK A;  3OIN A;  2Z0Y A;  4YQK A;  4YQT A;  3KW2 A;  4YVH A;  4MCC A;  4YPY A;  1ZJR A;  1WRT R;  4CNG A;  1NS5 A;  2YY8 A;  4YQN A;  4YQI A;  4CNF A;  1UAJ A;  4XBO A;  1UAM A;  1JHG A;  4YQQ A;  1V2X A;  4X3M A;  1CO0 A;  4JWH A;  1TO0 A;  4YQ6 A; 
#chains in the Genus database with same CATH homology
 4H3Z A;  1NXZ A;  4YQ3 A;  2CX8 A;  1P9P A;  4CND A;  3AI9 X;  3KY7 A;  4YQL A;  3ILK A;  3KTY A;  4FMW A;  4YQS A;  4J3C A;  4YQ4 A;  4YVK A;  4YVI A;  4YQ5 A;  3AIA A;  4JWG A;  1X7P A;  4YQR A;  4H3Y A;  2QWV A;  1K3R A;  4YPW A;  4MCB A;  4E8B A;  4X3L A;  4YQO A;  3ONP A;  4YQA A;  2EGV A;  4YQD A;  1MXI A;  4YQ8 A;  4YQ9 A;  1X7O A;  4YQ1 A;  4IG6 A;  3IC6 A;  1IPA A;  1O6D A;  4L69 A;  5GMB A;  4YVG A;  4YVJ A;  1VHK A;  4YPZ A;  2V3K A;  3E5Y A;  1Z85 A;  5GM8 A;  2V3J A;  1V6Z A;  5GMC A;  4YQG A;  5D9F A;  4YQJ A;  4YPX A;  4JWF A;  3OIJ A;  3BBD A;  1OY5 A;  4YQ2 A;  3IEF A;  4KGN A;  2HA8 A;  4PZK A;  4YQC A;  3AXZ A;  4YQ7 A;  1UAL A;  4CNE A;  3KNU A;  3NK7 A;  3N4J A;  3DCM X;  3QUV A;  4KDZ A;  1J85 A;  4YQ0 A;  1VH0 A;  1UAK A;  2QMM A;  4RG1 A;  3L8U A;  1VHY A;  4JWJ A;  5FAI A;  2I6D A;  3BBH A;  4FAK A;  5CO4 A;  3O7B A;  4MCD A;  4YQP A;  4YQB A;  4JAL A;  3OII A;  3NK6 A;  2EGW A;  3GYQ A;  3BBE A;  3N4K A;  1GZ0 A;  2O3A A;  4JAK A;  3OIN A;  2Z0Y A;  4YQK A;  4YQT A;  3KW2 A;  4YVH A;  4MCC A;  4YPY A;  1ZJR A;  4CNG A;  1NS5 A;  2YY8 A;  4YQN A;  4YQI A;  4CNF A;  1UAJ A;  4XBO A;  1UAM A;  4YQQ A;  1V2X A;  4X3M A;  4JWH A;  1TO0 A;  4YQ6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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