4YVHA

Crystal structure of h. influenzae trmd in complex with sinefungin
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
Knots found
sequence length
248
structure length
240
Chain Sequence
SHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLDSFADGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for methyl-donor-dependent and sequence-specific binding to tRNA substrates by knotted methyltransferase TrmD.
pubmed doi rcsb
molecule tags Transferase
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 74
structure length 240
sequence length 248
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yvhA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yvhA01
4YPYA 3AIAA 4YVIA 3L8UA 3N4KA 4CNDA 4YQPA 2QMMA 4YQ6A 3OIIA 4E8BA 3KY7A 4YVJA 3NK7A 5CO4A 4YQ1A 2CX8A 4CNGA 2V3JA 3OINA 1O6DA 4YQ3A 4MCBA 3N4JA 1UAKA 2I6DA 1VH0A 3QUVA 2YY8A 1ZJRA 1Z85A 4YQSA 1GZ0A 4YQ0A 1MXIA 4CNEA 1K3RA 2EGWA 4YQ4A 3O7BA 4H3YA 4YVKA 2Z0YA 4YQBA 4CNFA 3ONPA 1X7PA 4YQOA 4YPWA 4YQAA 1V2XA 3KTYA 4YQQA 5D9FA 3GYQA 4J3CA 4YQ5A 4FAKA 4YQNA 4YPZA 5GMCA 4YQ7A 3KW2A 4YQDA 1V6ZA 4YPXA 1NS5A 5GMBA 4H3ZA 1J85A 1OY5A 4RG1A 5GM8A 4JALA 3IC6A 1UAMA 4YVGA 1VHKA 4X3MA 3OIJA 1NXZA 4XBOA 1X7OA 3AI9X 4YQKA 2V3KA 4YQGA 1VHYA 4MCCA 1IPAA 3BBEA 4YQ9A 3E5YA 3KNUA 4KDZA 3ILKA 4YQCA 5FAIA 4JAKA 2EGVA 3BBHA 4YQIA 4MCDA 4L69A 4YQTA 4YQLA 3DCMX 2QWVA 1UALA 1UAJA 3AXZA 1P9PA 4IG6A 4YVHA 3BBDA 4YQRA 4PZKA 4YQ2A 3IEFA 3NK6A 4YQJA 4KGNA 2HA8A 4YQ8A 2O3AA 1TO0A 4X3LA
chains in the Genus database with same CATH superfamily
4YPYA 3AIAA 4YVIA 3L8UA 3N4KA 4CNDA 4YQPA 2QMMA 1TROA 4YQ6A 3OIIA 4E8BA 3KY7A 4YVJA 3NK7A 5CO4A 4YQ1A 2CX8A 4CNGA 2V3JA 3OINA 1O6DA 4YQ3A 4MCBA 3N4JA 1UAKA 2I6DA 1VH0A 1JHGA 4FMWA 3QUVA 2YY8A 1ZJRA 1Z85A 4JWGA 4YQSA 1GZ0A 4YQ0A 3FRWA 1MXIA 4CNEA 1K3RA 4YQ4A 2EGWA 3O7BA 4H3YA 4YVKA 2Z0YA 4YQBA 4CNFA 3ONPA 1X7PA 4YQOA 4YPWA 4YQAA 1V2XA 3KTYA 4YQQA 5D9FA 3GYQA 4J3CA 4YQ5A 4FAKA 4JWJA 4YQNA 4YPZA 5GMCA 4YQ7A 3WRPA 3KW2A 4YQDA 1WRSR 1V6ZA 4YPXA 1NS5A 1WRPR 5GMBA 4H3ZA 1J85A 1TRRA 1OY5A 2HA8A 4RG1A 1MI7R 5GM8A 4JALA 3IC6A 1UAMA 4YVGA 1VHKA 4JWHA 4X3MA 3OIJA 2OZ9R 1NXZA 4XBOA 1X7OA 3AI9X 4YQKA 2V3KA 4YQGA 1WRTR 4MCCA 1VHYA 2XDIA 1IPAA 3BBEA 4YQ9A 3E5YA 3KNUA 4KDZA 3ILKA 4YQCA 5FAIA 4JAKA 1ZT9A 2EGVA 3BBHA 4YQIA 4MCDA 4L69A 1RCSA 4YQTA 3G1CA 3KORA 4JWFA 4YQLA 3DCMX 2QWVA 1UALA 1UAJA 3AXZA 1P9PA 4IG6A 4YVHA 3BBDA 4YQRA 4PZKA 4YQ2A 3IEFA 3NK6A 1CO0A 4YQJA 4KGNA 3SSWN 3SSXN 4YQ8A 2O3AA 1TO0A 4X3LA
chains in the Genus database with same CATH topology
4YPYA 3AIAA 4YVIA 3L8UA 3N4KA 4CNDA 4YQPA 2QMMA 4YQ6A 3OIIA 4E8BA 3KY7A 4YVJA 3NK7A 5CO4A 4YQ1A 2CX8A 4CNGA 2V3JA 3OINA 1O6DA 4YQ3A 4MCBA 3N4JA 1UAKA 2I6DA 1VH0A 4FMWA 3QUVA 2YY8A 1ZJRA 1Z85A 4JWGA 4YQSA 1GZ0A 4YQ0A 1MXIA 4CNEA 1K3RA 2EGWA 4YQ4A 3O7BA 4H3YA 4YVKA 2Z0YA 4YQBA 4CNFA 3ONPA 1X7PA 4YQOA 4YPWA 4YQAA 1V2XA 3KTYA 4YQQA 5D9FA 3GYQA 4J3CA 4YQ5A 4FAKA 4JWJA 4YQNA 4YPZA 5GMCA 4YQ7A 3KW2A 4YQDA 1V6ZA 4YPXA 1NS5A 5GMBA 4H3ZA 1J85A 1OY5A 4RG1A 5GM8A 4JALA 3IC6A 1UAMA 4YVGA 1VHKA 4JWHA 4X3MA 3OIJA 1NXZA 4XBOA 1X7OA 3AI9X 4YQKA 2V3KA 4YQGA 1VHYA 4MCCA 1IPAA 3BBEA 4YQ9A 3E5YA 3KNUA 4KDZA 3ILKA 4YQCA 5FAIA 4JAKA 2EGVA 3BBHA 4YQIA 4MCDA 4L69A 4YQTA 4JWFA 4YQLA 3DCMX 2QWVA 1UALA 1UAJA 3AXZA 1P9PA 4IG6A 4YVHA 3BBDA 4YQRA 4PZKA 4YQ2A 3IEFA 3NK6A 4YQJA 4KGNA 2HA8A 4YQ8A 2O3AA 1TO0A 4X3LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YPY A;  3AIA A;  4YVI A;  3L8U A;  3N4K A;  4CND A;  4YQP A;  2QMM A;  4YQ6 A;  3OII A;  4E8B A;  3KY7 A;  4YVJ A;  3NK7 A;  5CO4 A;  4YQ1 A;  2CX8 A;  4CNG A;  2V3J A;  3OIN A;  1O6D A;  4YQ3 A;  4MCB A;  3N4J A;  1UAK A;  2I6D A;  1VH0 A;  3QUV A;  2YY8 A;  1ZJR A;  1Z85 A;  4YQS A;  1GZ0 A;  4YQ0 A;  1MXI A;  4CNE A;  1K3R A;  2EGW A;  4YQ4 A;  3O7B A;  4H3Y A;  4YVK A;  2Z0Y A;  4YQB A;  4CNF A;  3ONP A;  1X7P A;  4YQO A;  4YPW A;  4YQA A;  1V2X A;  3KTY A;  4YQQ A;  5D9F A;  3GYQ A;  4J3C A;  4YQ5 A;  4FAK A;  4YQN A;  4YPZ A;  5GMC A;  4YQ7 A;  3KW2 A;  4YQD A;  1V6Z A;  4YPX A;  1NS5 A;  5GMB A;  4H3Z A;  1J85 A;  1OY5 A;  4RG1 A;  5GM8 A;  4JAL A;  3IC6 A;  1UAM A;  4YVG A;  1VHK A;  4X3M A;  3OIJ A;  1NXZ A;  4XBO A;  1X7O A;  3AI9 X;  4YQK A;  2V3K A;  4YQG A;  1VHY A;  4MCC A;  1IPA A;  3BBE A;  4YQ9 A;  3E5Y A;  3KNU A;  4KDZ A;  3ILK A;  4YQC A;  5FAI A;  4JAK A;  2EGV A;  3BBH A;  4YQI A;  4MCD A;  4L69 A;  4YQT A;  4YQL A;  3DCM X;  2QWV A;  1UAL A;  1UAJ A;  3AXZ A;  1P9P A;  4IG6 A;  4YVH A;  3BBD A;  4YQR A;  4PZK A;  4YQ2 A;  3IEF A;  3NK6 A;  4YQJ A;  4KGN A;  2HA8 A;  4YQ8 A;  2O3A A;  1TO0 A;  4X3L A; 
#chains in the Genus database with same CATH topology
 4YPY A;  3AIA A;  4YVI A;  3L8U A;  3N4K A;  4CND A;  4YQP A;  2QMM A;  1TRO A;  4YQ6 A;  3OII A;  4E8B A;  3KY7 A;  4YVJ A;  3NK7 A;  5CO4 A;  4YQ1 A;  2CX8 A;  4CNG A;  2V3J A;  3OIN A;  1O6D A;  4YQ3 A;  4MCB A;  3N4J A;  1UAK A;  2I6D A;  1VH0 A;  1JHG A;  4FMW A;  3QUV A;  2YY8 A;  1ZJR A;  1Z85 A;  4JWG A;  4YQS A;  1GZ0 A;  4YQ0 A;  3FRW A;  1MXI A;  4CNE A;  1K3R A;  4YQ4 A;  2EGW A;  3O7B A;  4H3Y A;  4YVK A;  2Z0Y A;  4YQB A;  4CNF A;  3ONP A;  1X7P A;  4YQO A;  4YPW A;  4YQA A;  1V2X A;  3KTY A;  4YQQ A;  5D9F A;  3GYQ A;  4J3C A;  4YQ5 A;  4FAK A;  4JWJ A;  4YQN A;  4YPZ A;  5GMC A;  4YQ7 A;  3WRP A;  3KW2 A;  4YQD A;  1WRS R;  1V6Z A;  4YPX A;  1NS5 A;  1WRP R;  5GMB A;  4H3Z A;  1J85 A;  1TRR A;  1OY5 A;  2HA8 A;  4RG1 A;  1MI7 R;  5GM8 A;  4JAL A;  3IC6 A;  1UAM A;  4YVG A;  1VHK A;  4JWH A;  4X3M A;  3OIJ A;  2OZ9 R;  1NXZ A;  4XBO A;  1X7O A;  3AI9 X;  4YQK A;  2V3K A;  4YQG A;  1WRT R;  4MCC A;  1VHY A;  2XDI A;  1IPA A;  3BBE A;  4YQ9 A;  3E5Y A;  3KNU A;  4KDZ A;  3ILK A;  4YQC A;  5FAI A;  4JAK A;  1ZT9 A;  2EGV A;  3BBH A;  4YQI A;  4MCD A;  4L69 A;  1RCS A;  4YQT A;  3G1C A;  3KOR A;  4JWF A;  4YQL A;  3DCM X;  2QWV A;  1UAL A;  1UAJ A;  3AXZ A;  1P9P A;  4IG6 A;  4YVH A;  3BBD A;  4YQR A;  4PZK A;  4YQ2 A;  3IEF A;  3NK6 A;  1CO0 A;  4YQJ A;  4KGN A;  3SSW N;  3SSX N;  4YQ8 A;  2O3A A;  1TO0 A;  4X3L A; 
#chains in the Genus database with same CATH homology
 4YPY A;  3AIA A;  4YVI A;  3L8U A;  3N4K A;  4CND A;  4YQP A;  2QMM A;  4YQ6 A;  3OII A;  4E8B A;  3KY7 A;  4YVJ A;  3NK7 A;  5CO4 A;  4YQ1 A;  2CX8 A;  4CNG A;  2V3J A;  3OIN A;  1O6D A;  4YQ3 A;  4MCB A;  3N4J A;  1UAK A;  2I6D A;  1VH0 A;  4FMW A;  3QUV A;  2YY8 A;  1ZJR A;  1Z85 A;  4JWG A;  4YQS A;  1GZ0 A;  4YQ0 A;  1MXI A;  4CNE A;  1K3R A;  2EGW A;  4YQ4 A;  3O7B A;  4H3Y A;  4YVK A;  2Z0Y A;  4YQB A;  4CNF A;  3ONP A;  1X7P A;  4YQO A;  4YPW A;  4YQA A;  1V2X A;  3KTY A;  4YQQ A;  5D9F A;  3GYQ A;  4J3C A;  4YQ5 A;  4FAK A;  4JWJ A;  4YQN A;  4YPZ A;  5GMC A;  4YQ7 A;  3KW2 A;  4YQD A;  1V6Z A;  4YPX A;  1NS5 A;  5GMB A;  4H3Z A;  1J85 A;  1OY5 A;  4RG1 A;  5GM8 A;  4JAL A;  3IC6 A;  1UAM A;  4YVG A;  1VHK A;  4JWH A;  4X3M A;  3OIJ A;  1NXZ A;  4XBO A;  1X7O A;  3AI9 X;  4YQK A;  2V3K A;  4YQG A;  1VHY A;  4MCC A;  1IPA A;  3BBE A;  4YQ9 A;  3E5Y A;  3KNU A;  4KDZ A;  3ILK A;  4YQC A;  5FAI A;  4JAK A;  2EGV A;  3BBH A;  4YQI A;  4MCD A;  4L69 A;  4YQT A;  4JWF A;  4YQL A;  3DCM X;  2QWV A;  1UAL A;  1UAJ A;  3AXZ A;  1P9P A;  4IG6 A;  4YVH A;  3BBD A;  4YQR A;  4PZK A;  4YQ2 A;  3IEF A;  3NK6 A;  4YQJ A;  4KGN A;  2HA8 A;  4YQ8 A;  2O3A A;  1TO0 A;  4X3L A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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