4YVIA

Crystal structure of h. influenzae trmd in complex with sinefungin and trna
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
Knots found
sequence length
247
structure length
239
Chain Sequence
HMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLDSFADGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/rna
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
publication title Structural basis for methyl-donor-dependent and sequence-specific binding to tRNA substrates by knotted methyltransferase TrmD.
pubmed doi rcsb
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 65
structure length 239
sequence length 247
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yviA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yviA01
4YQRA 4YVHA 4YQ2A 3BBHA 4YQ1A 4CNDA 4YVJA 3KNUA 1MXIA 4YQLA 4YQNA 1VH0A 4FAKA 4YVIA 3OIIA 4YQ3A 3L8UA 4CNFA 5D9FA 1VHKA 4YQGA 1UAMA 4YVGA 4JAKA 2QMMA 4YQDA 1GZ0A 4YQ5A 3KW2A 1X7PA 2I6DA 3KTYA 3AIAA 3N4JA 1ZJRA 3AXZA 1V2XA 3IC6A 4CNEA 2YY8A 4YQAA 4X3LA 1UAKA 4RG1A 4YQKA 2CX8A 4YQ6A 1UAJA 5GMCA 4KDZA 5CO4A 4YPYA 4KGNA 1VHYA 5GM8A 4YQOA 5GMBA 1NXZA 3O7BA 4YPWA 5FAIA 4YVKA 4YQJA 4YQPA 1O6DA 1X7OA 4MCCA 4YPXA 4E8BA 2HA8A 4IG6A 2V3KA 1Z85A 3DCMX 4MCBA 3OIJA 4L69A 3BBEA 3KY7A 1OY5A 4YPZA 3NK7A 4YQ9A 4YQ0A 3ILKA 2V3JA 4XBOA 4YQ4A 2QWVA 1P9PA 4YQ7A 3AI9X 2Z0YA 4MCDA 2EGWA 3NK6A 4YQIA 4YQTA 4YQSA 1IPAA 4J3CA 3QUVA 4YQCA 3IEFA 4H3YA 1J85A 1K3RA 3ONPA 4X3MA 1TO0A 1UALA 3N4KA 3OINA 4H3ZA 4PZKA 4CNGA 4YQQA 3E5YA 4YQ8A 3GYQA 4JALA 2O3AA 3BBDA 4YQBA 2EGVA 1V6ZA 1NS5A
chains in the Genus database with same CATH superfamily
4YQRA 4YVHA 4YQ2A 3BBHA 1WRTR 4YQ1A 3WRPA 4FMWA 4CNDA 4YVJA 3KNUA 1MXIA 4YQLA 4YQNA 1VH0A 4FAKA 4YVIA 3OIIA 4YQ3A 3L8UA 4CNFA 5D9FA 1VHKA 4YQGA 1TRRA 1UAMA 4YVGA 4JAKA 1JHGA 2QMMA 4YQDA 1GZ0A 4YQ5A 3KW2A 1X7PA 2I6DA 3KTYA 3AIAA 3N4JA 1ZJRA 1CO0A 2OZ9R 3AXZA 1V2XA 3IC6A 4CNEA 2YY8A 4YQAA 4X3LA 1UAKA 1ZT9A 4RG1A 1WRPR 4YQKA 4YQ6A 3SSWN 1UAJA 2CX8A 5GMCA 4KDZA 5CO4A 4YPYA 4KGNA 4JWHA 1VHYA 5GM8A 4YQOA 5GMBA 1NXZA 1MI7R 3O7BA 4YPWA 5FAIA 4YVKA 4YQJA 4YQPA 1O6DA 1X7OA 4MCCA 4YPXA 4E8BA 2HA8A 4JWGA 4IG6A 2V3KA 1Z85A 3DCMX 4MCBA 3OIJA 4L69A 3BBEA 3KY7A 1OY5A 4YPZA 3NK7A 4YQ9A 4YQ0A 3ILKA 4JWFA 2V3JA 4XBOA 4YQ4A 2QWVA 1P9PA 4YQ7A 3AI9X 2Z0YA 4MCDA 2EGWA 1RCSA 3NK6A 4YQIA 4YQTA 4YQSA 1IPAA 3KORA 4J3CA 3QUVA 4YQCA 3IEFA 1TROA 3G1CA 4H3YA 1J85A 1K3RA 4JWJA 3ONPA 4X3MA 1TO0A 1UALA 3N4KA 3SSXN 1WRSR 3OINA 4H3ZA 4PZKA 4CNGA 2XDIA 4YQQA 3E5YA 4YQ8A 3GYQA 4JALA 2O3AA 3BBDA 3FRWA 4YQBA 2EGVA 1V6ZA 1NS5A
chains in the Genus database with same CATH topology
4YQRA 4YVHA 4YQ2A 3BBHA 4YQ1A 4CNDA 4FMWA 4YVJA 3KNUA 1MXIA 4YQLA 4YQNA 1VH0A 4FAKA 4YVIA 3OIIA 4YQ3A 3L8UA 4CNFA 5D9FA 1VHKA 4YQGA 1UAMA 4YVGA 4JAKA 2QMMA 4YQDA 1GZ0A 4YQ5A 3KW2A 1X7PA 2I6DA 3KTYA 3AIAA 3N4JA 1ZJRA 3AXZA 1V2XA 3IC6A 4CNEA 2YY8A 4YQAA 4X3LA 1UAKA 4RG1A 4YQKA 2CX8A 4YQ6A 1UAJA 5GMCA 4KDZA 5CO4A 4YPYA 4KGNA 4JWHA 1VHYA 5GM8A 4YQOA 5GMBA 1NXZA 3O7BA 4YPWA 5FAIA 4YVKA 4YQJA 4YQPA 1O6DA 1X7OA 4MCCA 4YPXA 4E8BA 2HA8A 4JWGA 4IG6A 2V3KA 1Z85A 3DCMX 4MCBA 3OIJA 4L69A 3BBEA 3KY7A 1OY5A 4YPZA 3NK7A 4YQ9A 4YQ0A 3ILKA 4JWFA 2V3JA 4XBOA 4YQ4A 2QWVA 1P9PA 4YQ7A 3AI9X 2Z0YA 4MCDA 2EGWA 3NK6A 4YQIA 4YQTA 4YQSA 1IPAA 4J3CA 3QUVA 4YQCA 3IEFA 4H3YA 1J85A 1K3RA 4JWJA 3ONPA 4X3MA 1TO0A 1UALA 3N4KA 3OINA 4H3ZA 4PZKA 4CNGA 4YQQA 3E5YA 4YQ8A 3GYQA 4JALA 2O3AA 3BBDA 4YQBA 2EGVA 1V6ZA 1NS5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YQR A;  4YVH A;  4YQ2 A;  3BBH A;  4YQ1 A;  4CND A;  4YVJ A;  3KNU A;  1MXI A;  4YQL A;  4YQN A;  1VH0 A;  4FAK A;  4YVI A;  3OII A;  4YQ3 A;  3L8U A;  4CNF A;  5D9F A;  1VHK A;  4YQG A;  1UAM A;  4YVG A;  4JAK A;  2QMM A;  4YQD A;  1GZ0 A;  4YQ5 A;  3KW2 A;  1X7P A;  2I6D A;  3KTY A;  3AIA A;  3N4J A;  1ZJR A;  3AXZ A;  1V2X A;  3IC6 A;  4CNE A;  2YY8 A;  4YQA A;  4X3L A;  1UAK A;  4RG1 A;  4YQK A;  2CX8 A;  4YQ6 A;  1UAJ A;  5GMC A;  4KDZ A;  5CO4 A;  4YPY A;  4KGN A;  1VHY A;  5GM8 A;  4YQO A;  5GMB A;  1NXZ A;  3O7B A;  4YPW A;  5FAI A;  4YVK A;  4YQJ A;  4YQP A;  1O6D A;  1X7O A;  4MCC A;  4YPX A;  4E8B A;  2HA8 A;  4IG6 A;  2V3K A;  1Z85 A;  3DCM X;  4MCB A;  3OIJ A;  4L69 A;  3BBE A;  3KY7 A;  1OY5 A;  4YPZ A;  3NK7 A;  4YQ9 A;  4YQ0 A;  3ILK A;  2V3J A;  4XBO A;  4YQ4 A;  2QWV A;  1P9P A;  4YQ7 A;  3AI9 X;  2Z0Y A;  4MCD A;  2EGW A;  3NK6 A;  4YQI A;  4YQT A;  4YQS A;  1IPA A;  4J3C A;  3QUV A;  4YQC A;  3IEF A;  4H3Y A;  1J85 A;  1K3R A;  3ONP A;  4X3M A;  1TO0 A;  1UAL A;  3N4K A;  3OIN A;  4H3Z A;  4PZK A;  4CNG A;  4YQQ A;  3E5Y A;  4YQ8 A;  3GYQ A;  4JAL A;  2O3A A;  3BBD A;  4YQB A;  2EGV A;  1V6Z A;  1NS5 A; 
#chains in the Genus database with same CATH topology
 4YQR A;  4YVH A;  4YQ2 A;  3BBH A;  1WRT R;  4YQ1 A;  3WRP A;  4FMW A;  4CND A;  4YVJ A;  3KNU A;  1MXI A;  4YQL A;  4YQN A;  1VH0 A;  4FAK A;  4YVI A;  3OII A;  4YQ3 A;  3L8U A;  4CNF A;  5D9F A;  1VHK A;  4YQG A;  1TRR A;  1UAM A;  4YVG A;  4JAK A;  1JHG A;  2QMM A;  4YQD A;  1GZ0 A;  4YQ5 A;  3KW2 A;  1X7P A;  2I6D A;  3KTY A;  3AIA A;  3N4J A;  1ZJR A;  1CO0 A;  2OZ9 R;  3AXZ A;  1V2X A;  3IC6 A;  4CNE A;  2YY8 A;  4YQA A;  4X3L A;  1UAK A;  1ZT9 A;  4RG1 A;  1WRP R;  4YQK A;  4YQ6 A;  3SSW N;  1UAJ A;  2CX8 A;  5GMC A;  4KDZ A;  5CO4 A;  4YPY A;  4KGN A;  4JWH A;  1VHY A;  5GM8 A;  4YQO A;  5GMB A;  1NXZ A;  1MI7 R;  3O7B A;  4YPW A;  5FAI A;  4YVK A;  4YQJ A;  4YQP A;  1O6D A;  1X7O A;  4MCC A;  4YPX A;  4E8B A;  2HA8 A;  4JWG A;  4IG6 A;  2V3K A;  1Z85 A;  3DCM X;  4MCB A;  3OIJ A;  4L69 A;  3BBE A;  3KY7 A;  1OY5 A;  4YPZ A;  3NK7 A;  4YQ9 A;  4YQ0 A;  3ILK A;  4JWF A;  2V3J A;  4XBO A;  4YQ4 A;  2QWV A;  1P9P A;  4YQ7 A;  3AI9 X;  2Z0Y A;  4MCD A;  2EGW A;  1RCS A;  3NK6 A;  4YQI A;  4YQT A;  4YQS A;  1IPA A;  3KOR A;  4J3C A;  3QUV A;  4YQC A;  3IEF A;  1TRO A;  3G1C A;  4H3Y A;  1J85 A;  1K3R A;  4JWJ A;  3ONP A;  4X3M A;  1TO0 A;  1UAL A;  3N4K A;  3SSX N;  1WRS R;  3OIN A;  4H3Z A;  4PZK A;  4CNG A;  2XDI A;  4YQQ A;  3E5Y A;  4YQ8 A;  3GYQ A;  4JAL A;  2O3A A;  3BBD A;  3FRW A;  4YQB A;  2EGV A;  1V6Z A;  1NS5 A; 
#chains in the Genus database with same CATH homology
 4YQR A;  4YVH A;  4YQ2 A;  3BBH A;  4YQ1 A;  4CND A;  4FMW A;  4YVJ A;  3KNU A;  1MXI A;  4YQL A;  4YQN A;  1VH0 A;  4FAK A;  4YVI A;  3OII A;  4YQ3 A;  3L8U A;  4CNF A;  5D9F A;  1VHK A;  4YQG A;  1UAM A;  4YVG A;  4JAK A;  2QMM A;  4YQD A;  1GZ0 A;  4YQ5 A;  3KW2 A;  1X7P A;  2I6D A;  3KTY A;  3AIA A;  3N4J A;  1ZJR A;  3AXZ A;  1V2X A;  3IC6 A;  4CNE A;  2YY8 A;  4YQA A;  4X3L A;  1UAK A;  4RG1 A;  4YQK A;  2CX8 A;  4YQ6 A;  1UAJ A;  5GMC A;  4KDZ A;  5CO4 A;  4YPY A;  4KGN A;  4JWH A;  1VHY A;  5GM8 A;  4YQO A;  5GMB A;  1NXZ A;  3O7B A;  4YPW A;  5FAI A;  4YVK A;  4YQJ A;  4YQP A;  1O6D A;  1X7O A;  4MCC A;  4YPX A;  4E8B A;  2HA8 A;  4JWG A;  4IG6 A;  2V3K A;  1Z85 A;  3DCM X;  4MCB A;  3OIJ A;  4L69 A;  3BBE A;  3KY7 A;  1OY5 A;  4YPZ A;  3NK7 A;  4YQ9 A;  4YQ0 A;  3ILK A;  4JWF A;  2V3J A;  4XBO A;  4YQ4 A;  2QWV A;  1P9P A;  4YQ7 A;  3AI9 X;  2Z0Y A;  4MCD A;  2EGW A;  3NK6 A;  4YQI A;  4YQT A;  4YQS A;  1IPA A;  4J3C A;  3QUV A;  4YQC A;  3IEF A;  4H3Y A;  1J85 A;  1K3R A;  4JWJ A;  3ONP A;  4X3M A;  1TO0 A;  1UAL A;  3N4K A;  3OIN A;  4H3Z A;  4PZK A;  4CNG A;  4YQQ A;  3E5Y A;  4YQ8 A;  3GYQ A;  4JAL A;  2O3A A;  3BBD A;  4YQB A;  2EGV A;  1V6Z A;  1NS5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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