4YVIA

Crystal structure of h. influenzae trmd in complex with sinefungin and trna
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
Knots found
sequence length
247
structure length
239
Chain Sequence
HMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLDSFADGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for methyl-donor-dependent and sequence-specific binding to tRNA substrates by knotted methyltransferase TrmD.
pubmed doi rcsb
molecule tags Transferase/rna
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 65
structure length 239
sequence length 247
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yviA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yviA01
1VHKA 2YY8A 3KY7A 4YVIA 4CNEA 5D9FA 4H3YA 3AIAA 1X7PA 2Z0YA 2QMMA 4YQ6A 4YQKA 4X3LA 1NS5A 3AXZA 3BBHA 1IPAA 4YQ9A 1NXZA 3QUVA 3OINA 4YVHA 4YQDA 2I6DA 1V2XA 1V6ZA 4YQGA 1Z85A 1UAMA 3BBEA 3NK7A 4L69A 4YPZA 1UAKA 1X7OA 1UAJA 4YQAA 1K3RA 1OY5A 4CNDA 4YQ7A 4YQOA 3N4KA 4YQBA 1ZJRA 4CNFA 4MCCA 4YQCA 4YQPA 5GMBA 4H3ZA 4X3MA 4YPWA 1P9PA 3IEFA 4FAKA 1GZ0A 4JALA 3KW2A 3BBDA 1UALA 3DCMX 4YVGA 4YQJA 2V3JA 3IC6A 3E5YA 4XBOA 3N4JA 5GMCA 4YVJA 3AI9X 4J3CA 5CO4A 4RG1A 2EGVA 4YQTA 2QWVA 4YQQA 2CX8A 4JAKA 2HA8A 4YQ8A 3OIIA 4CNGA 1J85A 3OIJA 1O6DA 4YPXA 4YQ0A 3ONPA 4YQLA 4KGNA 4YQ5A 4KDZA 3NK6A 5GM8A 1TO0A 1MXIA 5FAIA 1VH0A 4YQIA 3KTYA 2V3KA 4YVKA 4YQ3A 4YQSA 4MCBA 4PZKA 4IG6A 2O3AA 4YPYA 4YQNA 4YQ4A 4YQRA 4MCDA 1VHYA 2EGWA 3O7BA 3L8UA 4YQ2A 4YQ1A 3ILKA 3GYQA 4E8BA 3KNUA
chains in the Genus database with same CATH superfamily
1TRRA 1VHKA 2YY8A 3KY7A 4YVIA 4CNEA 5D9FA 4H3YA 3AIAA 1X7PA 2Z0YA 2QMMA 1WRTR 4YQ6A 4YQKA 1NS5A 3AXZA 3BBHA 4X3LA 1IPAA 1WRSR 4YQ9A 1NXZA 3QUVA 3OINA 4YVHA 4YQDA 2I6DA 1V2XA 1V6ZA 4YQGA 1Z85A 4FMWA 3KORA 1UAMA 3BBEA 3NK7A 4L69A 1CO0A 4YPZA 1UAKA 1X7OA 1UAJA 4YQAA 1K3RA 1OY5A 4CNDA 4YQ7A 4YQOA 3N4KA 4YQBA 1ZJRA 4CNFA 3G1CA 2XDIA 4MCCA 4YQCA 3SSWN 4YQPA 1WRPR 5GMBA 4H3ZA 1TROA 4YPWA 4X3MA 1P9PA 3IEFA 4JWFA 4FAKA 1GZ0A 4JALA 1ZT9A 3KW2A 3BBDA 1UALA 3DCMX 4YVGA 4YQJA 2V3JA 3IC6A 3E5YA 4XBOA 3N4JA 5GMCA 4YVJA 3AI9X 4J3CA 3WRPA 5CO4A 4RG1A 2EGVA 4YQTA 2QWVA 4YQQA 4JWHA 2CX8A 4JAKA 3SSXN 2HA8A 4YQ8A 3OIIA 4CNGA 1J85A 3OIJA 1O6DA 4YPXA 3FRWA 4YQ0A 3ONPA 4YQLA 4KGNA 1JHGA 4YQ5A 4KDZA 3NK6A 5GM8A 1RCSA 1TO0A 2OZ9R 1MXIA 5FAIA 1VH0A 4YQIA 1MI7R 3KTYA 4JWJA 2V3KA 4YVKA 4YQ3A 4JWGA 4YQSA 4MCBA 4PZKA 4IG6A 2O3AA 4YPYA 4YQNA 4YQ4A 4YQRA 4MCDA 1VHYA 2EGWA 3O7BA 3L8UA 4YQ2A 4YQ1A 3ILKA 3GYQA 4E8BA 3KNUA
chains in the Genus database with same CATH topology
1VHKA 2YY8A 3KY7A 4YVIA 4CNEA 5D9FA 4H3YA 3AIAA 1X7PA 2Z0YA 2QMMA 4YQ6A 4YQKA 4X3LA 1NS5A 3AXZA 3BBHA 1IPAA 4YQ9A 1NXZA 3QUVA 3OINA 4YVHA 4YQDA 2I6DA 1V2XA 1V6ZA 4YQGA 1Z85A 4FMWA 1UAMA 3BBEA 3NK7A 4L69A 4YPZA 1UAKA 1X7OA 1UAJA 4YQAA 1K3RA 1OY5A 4CNDA 4YQ7A 4YQOA 3N4KA 4YQBA 1ZJRA 4CNFA 4MCCA 4YQCA 4YQPA 5GMBA 4H3ZA 4X3MA 4YPWA 1P9PA 3IEFA 4JWFA 4FAKA 1GZ0A 4JALA 3KW2A 3BBDA 1UALA 3DCMX 4YVGA 4YQJA 2V3JA 3IC6A 3E5YA 4XBOA 3N4JA 5GMCA 4YVJA 3AI9X 4J3CA 5CO4A 4RG1A 2EGVA 4YQTA 2QWVA 4YQQA 4JWHA 2CX8A 4JAKA 2HA8A 4YQ8A 3OIIA 4CNGA 1J85A 3OIJA 1O6DA 4YPXA 4YQ0A 3ONPA 4YQLA 4KGNA 4YQ5A 4KDZA 3NK6A 5GM8A 1TO0A 1MXIA 5FAIA 1VH0A 4YQIA 3KTYA 4JWJA 2V3KA 4YVKA 4YQ3A 4JWGA 4YQSA 4MCBA 4PZKA 4IG6A 2O3AA 4YPYA 4YQNA 4YQ4A 4YQRA 4MCDA 1VHYA 2EGWA 3O7BA 3L8UA 4YQ2A 4YQ1A 3ILKA 3GYQA 4E8BA 3KNUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VHK A;  2YY8 A;  3KY7 A;  4YVI A;  4CNE A;  5D9F A;  4H3Y A;  3AIA A;  1X7P A;  2Z0Y A;  2QMM A;  4YQ6 A;  4YQK A;  4X3L A;  1NS5 A;  3AXZ A;  3BBH A;  1IPA A;  4YQ9 A;  1NXZ A;  3QUV A;  3OIN A;  4YVH A;  4YQD A;  2I6D A;  1V2X A;  1V6Z A;  4YQG A;  1Z85 A;  1UAM A;  3BBE A;  3NK7 A;  4L69 A;  4YPZ A;  1UAK A;  1X7O A;  1UAJ A;  4YQA A;  1K3R A;  1OY5 A;  4CND A;  4YQ7 A;  4YQO A;  3N4K A;  4YQB A;  1ZJR A;  4CNF A;  4MCC A;  4YQC A;  4YQP A;  5GMB A;  4H3Z A;  4X3M A;  4YPW A;  1P9P A;  3IEF A;  4FAK A;  1GZ0 A;  4JAL A;  3KW2 A;  3BBD A;  1UAL A;  3DCM X;  4YVG A;  4YQJ A;  2V3J A;  3IC6 A;  3E5Y A;  4XBO A;  3N4J A;  5GMC A;  4YVJ A;  3AI9 X;  4J3C A;  5CO4 A;  4RG1 A;  2EGV A;  4YQT A;  2QWV A;  4YQQ A;  2CX8 A;  4JAK A;  2HA8 A;  4YQ8 A;  3OII A;  4CNG A;  1J85 A;  3OIJ A;  1O6D A;  4YPX A;  4YQ0 A;  3ONP A;  4YQL A;  4KGN A;  4YQ5 A;  4KDZ A;  3NK6 A;  5GM8 A;  1TO0 A;  1MXI A;  5FAI A;  1VH0 A;  4YQI A;  3KTY A;  2V3K A;  4YVK A;  4YQ3 A;  4YQS A;  4MCB A;  4PZK A;  4IG6 A;  2O3A A;  4YPY A;  4YQN A;  4YQ4 A;  4YQR A;  4MCD A;  1VHY A;  2EGW A;  3O7B A;  3L8U A;  4YQ2 A;  4YQ1 A;  3ILK A;  3GYQ A;  4E8B A;  3KNU A; 
#chains in the Genus database with same CATH topology
 1TRR A;  1VHK A;  2YY8 A;  3KY7 A;  4YVI A;  4CNE A;  5D9F A;  4H3Y A;  3AIA A;  1X7P A;  2Z0Y A;  2QMM A;  1WRT R;  4YQ6 A;  4YQK A;  1NS5 A;  3AXZ A;  3BBH A;  4X3L A;  1IPA A;  1WRS R;  4YQ9 A;  1NXZ A;  3QUV A;  3OIN A;  4YVH A;  4YQD A;  2I6D A;  1V2X A;  1V6Z A;  4YQG A;  1Z85 A;  4FMW A;  3KOR A;  1UAM A;  3BBE A;  3NK7 A;  4L69 A;  1CO0 A;  4YPZ A;  1UAK A;  1X7O A;  1UAJ A;  4YQA A;  1K3R A;  1OY5 A;  4CND A;  4YQ7 A;  4YQO A;  3N4K A;  4YQB A;  1ZJR A;  4CNF A;  3G1C A;  2XDI A;  4MCC A;  4YQC A;  3SSW N;  4YQP A;  1WRP R;  5GMB A;  4H3Z A;  1TRO A;  4YPW A;  4X3M A;  1P9P A;  3IEF A;  4JWF A;  4FAK A;  1GZ0 A;  4JAL A;  1ZT9 A;  3KW2 A;  3BBD A;  1UAL A;  3DCM X;  4YVG A;  4YQJ A;  2V3J A;  3IC6 A;  3E5Y A;  4XBO A;  3N4J A;  5GMC A;  4YVJ A;  3AI9 X;  4J3C A;  3WRP A;  5CO4 A;  4RG1 A;  2EGV A;  4YQT A;  2QWV A;  4YQQ A;  4JWH A;  2CX8 A;  4JAK A;  3SSX N;  2HA8 A;  4YQ8 A;  3OII A;  4CNG A;  1J85 A;  3OIJ A;  1O6D A;  4YPX A;  3FRW A;  4YQ0 A;  3ONP A;  4YQL A;  4KGN A;  1JHG A;  4YQ5 A;  4KDZ A;  3NK6 A;  5GM8 A;  1RCS A;  1TO0 A;  2OZ9 R;  1MXI A;  5FAI A;  1VH0 A;  4YQI A;  1MI7 R;  3KTY A;  4JWJ A;  2V3K A;  4YVK A;  4YQ3 A;  4JWG A;  4YQS A;  4MCB A;  4PZK A;  4IG6 A;  2O3A A;  4YPY A;  4YQN A;  4YQ4 A;  4YQR A;  4MCD A;  1VHY A;  2EGW A;  3O7B A;  3L8U A;  4YQ2 A;  4YQ1 A;  3ILK A;  3GYQ A;  4E8B A;  3KNU A; 
#chains in the Genus database with same CATH homology
 1VHK A;  2YY8 A;  3KY7 A;  4YVI A;  4CNE A;  5D9F A;  4H3Y A;  3AIA A;  1X7P A;  2Z0Y A;  2QMM A;  4YQ6 A;  4YQK A;  4X3L A;  1NS5 A;  3AXZ A;  3BBH A;  1IPA A;  4YQ9 A;  1NXZ A;  3QUV A;  3OIN A;  4YVH A;  4YQD A;  2I6D A;  1V2X A;  1V6Z A;  4YQG A;  1Z85 A;  4FMW A;  1UAM A;  3BBE A;  3NK7 A;  4L69 A;  4YPZ A;  1UAK A;  1X7O A;  1UAJ A;  4YQA A;  1K3R A;  1OY5 A;  4CND A;  4YQ7 A;  4YQO A;  3N4K A;  4YQB A;  1ZJR A;  4CNF A;  4MCC A;  4YQC A;  4YQP A;  5GMB A;  4H3Z A;  4X3M A;  4YPW A;  1P9P A;  3IEF A;  4JWF A;  4FAK A;  1GZ0 A;  4JAL A;  3KW2 A;  3BBD A;  1UAL A;  3DCM X;  4YVG A;  4YQJ A;  2V3J A;  3IC6 A;  3E5Y A;  4XBO A;  3N4J A;  5GMC A;  4YVJ A;  3AI9 X;  4J3C A;  5CO4 A;  4RG1 A;  2EGV A;  4YQT A;  2QWV A;  4YQQ A;  4JWH A;  2CX8 A;  4JAK A;  2HA8 A;  4YQ8 A;  3OII A;  4CNG A;  1J85 A;  3OIJ A;  1O6D A;  4YPX A;  4YQ0 A;  3ONP A;  4YQL A;  4KGN A;  4YQ5 A;  4KDZ A;  3NK6 A;  5GM8 A;  1TO0 A;  1MXI A;  5FAI A;  1VH0 A;  4YQI A;  3KTY A;  4JWJ A;  2V3K A;  4YVK A;  4YQ3 A;  4JWG A;  4YQS A;  4MCB A;  4PZK A;  4IG6 A;  2O3A A;  4YPY A;  4YQN A;  4YQ4 A;  4YQR A;  4MCD A;  1VHY A;  2EGW A;  3O7B A;  3L8U A;  4YQ2 A;  4YQ1 A;  3ILK A;  3GYQ A;  4E8B A;  3KNU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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