4YVJA

Crystal structure of h. influenzae trmd in complex with sinefungin and trna variant (g36u)
Total Genus 68
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
Knots found
sequence length
248
structure length
239
Chain Sequence
SHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVDSFADGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for methyl-donor-dependent and sequence-specific binding to tRNA substrates by knotted methyltransferase TrmD.
pubmed doi rcsb
molecule tags Transferase/rna
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 68
structure length 239
sequence length 248
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yvjA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yvjA01
3KNUA 4FAKA 3BBEA 5CO4A 2YY8A 4H3YA 4JAKA 1UAMA 1UAJA 4YQ5A 2V3JA 1IPAA 4J3CA 4YQJA 4MCCA 1MXIA 4YQ8A 4YQGA 3N4KA 3OINA 1V6ZA 4RG1A 2EGVA 4KGNA 3N4JA 1X7PA 4X3MA 4E8BA 4YQTA 4YQRA 4YQ4A 1K3RA 5D9FA 4H3ZA 4JALA 1GZ0A 2O3AA 3KW2A 5GMCA 3NK6A 4L69A 4YPYA 2HA8A 1ZJRA 4YQNA 2QMMA 3KTYA 4YVKA 4CNGA 4YQ7A 1VHYA 4CNEA 1TO0A 4YQLA 3OIJA 3ILKA 4YPXA 3BBDA 1UALA 3NK7A 3AIAA 4XBOA 4YQQA 3GYQA 3IEFA 3ONPA 3OIIA 4YVJA 1O6DA 2QWVA 4CNFA 3O7BA 2EGWA 4MCBA 1VHKA 4MCDA 1J85A 4YQ9A 4YQ0A 4PZKA 4YQAA 4KDZA 4YQBA 4YQKA 4YQDA 1OY5A 4CNDA 4YQ1A 4YQ3A 3QUVA 4YPWA 3BBHA 4YQ6A 4YQ2A 4YQIA 4X3LA 1P9PA 3AI9X 3L8UA 5GM8A 4YQCA 4IG6A 4YPZA 5GMBA 4YQPA 1UAKA 2V3KA 4YQOA 4YVHA 2I6DA 3KY7A 3DCMX 4YVGA 3AXZA 2CX8A 4YVIA 1Z85A 3E5YA 1VH0A 2Z0YA 1NXZA 1X7OA 3IC6A 4YQSA 1NS5A 1V2XA 5FAIA
chains in the Genus database with same CATH superfamily
3KNUA 4FAKA 3BBEA 3WRPA 5CO4A 2YY8A 4H3YA 4JAKA 1UAMA 1RCSA 1UAJA 4YQ5A 2V3JA 1WRTR 1IPAA 4J3CA 4YQJA 4MCCA 1MXIA 4YQ8A 4YQGA 3N4KA 3OINA 1V6ZA 4RG1A 1TRRA 2EGVA 4KGNA 3N4JA 1X7PA 4X3MA 4E8BA 4YQTA 4YQRA 4YQ4A 1K3RA 5D9FA 3SSXN 2OZ9R 4H3ZA 1CO0A 1GZ0A 4JALA 2O3AA 3KW2A 5GMCA 4JWGA 3KORA 3NK6A 4L69A 4YPYA 2HA8A 1ZJRA 4FMWA 4YQNA 2QMMA 3SSWN 3KTYA 4YVKA 4CNGA 4YQ7A 1VHYA 4CNEA 1TO0A 4YQLA 3OIJA 3ILKA 4YPXA 3BBDA 1UALA 3NK7A 3AIAA 4XBOA 4YQQA 3GYQA 3IEFA 3ONPA 3OIIA 4YVJA 1O6DA 1WRSR 2QWVA 4CNFA 3G1CA 3O7BA 2EGWA 4MCBA 1VHKA 4MCDA 1J85A 4YQ9A 4YQ0A 4PZKA 4YQAA 4KDZA 4YQBA 4YQKA 4YQDA 1OY5A 4CNDA 4YQ1A 4YQ3A 3QUVA 4YPWA 3BBHA 4YQ6A 4YQ2A 4YQIA 4X3LA 1P9PA 1MI7R 3AI9X 3L8UA 4JWFA 5GM8A 4YQCA 4IG6A 4YPZA 5GMBA 4YQPA 1UAKA 4JWJA 2V3KA 2XDIA 3FRWA 1WRPR 4YQOA 4YVHA 1JHGA 1ZT9A 2I6DA 3KY7A 3DCMX 4YVGA 3AXZA 2CX8A 1TROA 4YVIA 1Z85A 3E5YA 1VH0A 2Z0YA 1NXZA 1X7OA 3IC6A 4JWHA 4YQSA 1NS5A 1V2XA 5FAIA
chains in the Genus database with same CATH topology
3KNUA 4FAKA 3BBEA 5CO4A 2YY8A 4H3YA 4JAKA 1UAMA 1UAJA 4YQ5A 2V3JA 1IPAA 4J3CA 4YQJA 4MCCA 1MXIA 4YQ8A 4YQGA 3N4KA 3OINA 1V6ZA 4RG1A 2EGVA 4KGNA 3N4JA 1X7PA 4X3MA 4E8BA 4YQTA 4YQRA 4YQ4A 1K3RA 5D9FA 4H3ZA 4JALA 1GZ0A 2O3AA 3KW2A 5GMCA 4JWGA 3NK6A 4L69A 4YPYA 2HA8A 1ZJRA 4FMWA 4YQNA 2QMMA 3KTYA 4YVKA 4CNGA 4YQ7A 1VHYA 4CNEA 1TO0A 4YQLA 3OIJA 3ILKA 4YPXA 3BBDA 1UALA 3NK7A 3AIAA 4XBOA 4YQQA 3GYQA 3IEFA 3ONPA 3OIIA 4YVJA 1O6DA 2QWVA 4CNFA 3O7BA 2EGWA 4MCBA 1VHKA 4MCDA 1J85A 4YQ9A 4YQ0A 4PZKA 4YQAA 4KDZA 4YQBA 4YQKA 4YQDA 1OY5A 4CNDA 4YQ1A 4YQ3A 3QUVA 4YPWA 3BBHA 4YQ6A 4YQ2A 4YQIA 4X3LA 1P9PA 3AI9X 3L8UA 4JWFA 5GM8A 4YQCA 4IG6A 4YPZA 5GMBA 4YQPA 1UAKA 4JWJA 2V3KA 4YQOA 4YVHA 2I6DA 3KY7A 3DCMX 4YVGA 3AXZA 2CX8A 4YVIA 1Z85A 3E5YA 1VH0A 2Z0YA 1NXZA 1X7OA 3IC6A 4JWHA 4YQSA 1NS5A 1V2XA 5FAIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KNU A;  4FAK A;  3BBE A;  5CO4 A;  2YY8 A;  4H3Y A;  4JAK A;  1UAM A;  1UAJ A;  4YQ5 A;  2V3J A;  1IPA A;  4J3C A;  4YQJ A;  4MCC A;  1MXI A;  4YQ8 A;  4YQG A;  3N4K A;  3OIN A;  1V6Z A;  4RG1 A;  2EGV A;  4KGN A;  3N4J A;  1X7P A;  4X3M A;  4E8B A;  4YQT A;  4YQR A;  4YQ4 A;  1K3R A;  5D9F A;  4H3Z A;  4JAL A;  1GZ0 A;  2O3A A;  3KW2 A;  5GMC A;  3NK6 A;  4L69 A;  4YPY A;  2HA8 A;  1ZJR A;  4YQN A;  2QMM A;  3KTY A;  4YVK A;  4CNG A;  4YQ7 A;  1VHY A;  4CNE A;  1TO0 A;  4YQL A;  3OIJ A;  3ILK A;  4YPX A;  3BBD A;  1UAL A;  3NK7 A;  3AIA A;  4XBO A;  4YQQ A;  3GYQ A;  3IEF A;  3ONP A;  3OII A;  4YVJ A;  1O6D A;  2QWV A;  4CNF A;  3O7B A;  2EGW A;  4MCB A;  1VHK A;  4MCD A;  1J85 A;  4YQ9 A;  4YQ0 A;  4PZK A;  4YQA A;  4KDZ A;  4YQB A;  4YQK A;  4YQD A;  1OY5 A;  4CND A;  4YQ1 A;  4YQ3 A;  3QUV A;  4YPW A;  3BBH A;  4YQ6 A;  4YQ2 A;  4YQI A;  4X3L A;  1P9P A;  3AI9 X;  3L8U A;  5GM8 A;  4YQC A;  4IG6 A;  4YPZ A;  5GMB A;  4YQP A;  1UAK A;  2V3K A;  4YQO A;  4YVH A;  2I6D A;  3KY7 A;  3DCM X;  4YVG A;  3AXZ A;  2CX8 A;  4YVI A;  1Z85 A;  3E5Y A;  1VH0 A;  2Z0Y A;  1NXZ A;  1X7O A;  3IC6 A;  4YQS A;  1NS5 A;  1V2X A;  5FAI A; 
#chains in the Genus database with same CATH topology
 3KNU A;  4FAK A;  3BBE A;  3WRP A;  5CO4 A;  2YY8 A;  4H3Y A;  4JAK A;  1UAM A;  1RCS A;  1UAJ A;  4YQ5 A;  2V3J A;  1WRT R;  1IPA A;  4J3C A;  4YQJ A;  4MCC A;  1MXI A;  4YQ8 A;  4YQG A;  3N4K A;  3OIN A;  1V6Z A;  4RG1 A;  1TRR A;  2EGV A;  4KGN A;  3N4J A;  1X7P A;  4X3M A;  4E8B A;  4YQT A;  4YQR A;  4YQ4 A;  1K3R A;  5D9F A;  3SSX N;  2OZ9 R;  4H3Z A;  1CO0 A;  1GZ0 A;  4JAL A;  2O3A A;  3KW2 A;  5GMC A;  4JWG A;  3KOR A;  3NK6 A;  4L69 A;  4YPY A;  2HA8 A;  1ZJR A;  4FMW A;  4YQN A;  2QMM A;  3SSW N;  3KTY A;  4YVK A;  4CNG A;  4YQ7 A;  1VHY A;  4CNE A;  1TO0 A;  4YQL A;  3OIJ A;  3ILK A;  4YPX A;  3BBD A;  1UAL A;  3NK7 A;  3AIA A;  4XBO A;  4YQQ A;  3GYQ A;  3IEF A;  3ONP A;  3OII A;  4YVJ A;  1O6D A;  1WRS R;  2QWV A;  4CNF A;  3G1C A;  3O7B A;  2EGW A;  4MCB A;  1VHK A;  4MCD A;  1J85 A;  4YQ9 A;  4YQ0 A;  4PZK A;  4YQA A;  4KDZ A;  4YQB A;  4YQK A;  4YQD A;  1OY5 A;  4CND A;  4YQ1 A;  4YQ3 A;  3QUV A;  4YPW A;  3BBH A;  4YQ6 A;  4YQ2 A;  4YQI A;  4X3L A;  1P9P A;  1MI7 R;  3AI9 X;  3L8U A;  4JWF A;  5GM8 A;  4YQC A;  4IG6 A;  4YPZ A;  5GMB A;  4YQP A;  1UAK A;  4JWJ A;  2V3K A;  2XDI A;  3FRW A;  1WRP R;  4YQO A;  4YVH A;  1JHG A;  1ZT9 A;  2I6D A;  3KY7 A;  3DCM X;  4YVG A;  3AXZ A;  2CX8 A;  1TRO A;  4YVI A;  1Z85 A;  3E5Y A;  1VH0 A;  2Z0Y A;  1NXZ A;  1X7O A;  3IC6 A;  4JWH A;  4YQS A;  1NS5 A;  1V2X A;  5FAI A; 
#chains in the Genus database with same CATH homology
 3KNU A;  4FAK A;  3BBE A;  5CO4 A;  2YY8 A;  4H3Y A;  4JAK A;  1UAM A;  1UAJ A;  4YQ5 A;  2V3J A;  1IPA A;  4J3C A;  4YQJ A;  4MCC A;  1MXI A;  4YQ8 A;  4YQG A;  3N4K A;  3OIN A;  1V6Z A;  4RG1 A;  2EGV A;  4KGN A;  3N4J A;  1X7P A;  4X3M A;  4E8B A;  4YQT A;  4YQR A;  4YQ4 A;  1K3R A;  5D9F A;  4H3Z A;  4JAL A;  1GZ0 A;  2O3A A;  3KW2 A;  5GMC A;  4JWG A;  3NK6 A;  4L69 A;  4YPY A;  2HA8 A;  1ZJR A;  4FMW A;  4YQN A;  2QMM A;  3KTY A;  4YVK A;  4CNG A;  4YQ7 A;  1VHY A;  4CNE A;  1TO0 A;  4YQL A;  3OIJ A;  3ILK A;  4YPX A;  3BBD A;  1UAL A;  3NK7 A;  3AIA A;  4XBO A;  4YQQ A;  3GYQ A;  3IEF A;  3ONP A;  3OII A;  4YVJ A;  1O6D A;  2QWV A;  4CNF A;  3O7B A;  2EGW A;  4MCB A;  1VHK A;  4MCD A;  1J85 A;  4YQ9 A;  4YQ0 A;  4PZK A;  4YQA A;  4KDZ A;  4YQB A;  4YQK A;  4YQD A;  1OY5 A;  4CND A;  4YQ1 A;  4YQ3 A;  3QUV A;  4YPW A;  3BBH A;  4YQ6 A;  4YQ2 A;  4YQI A;  4X3L A;  1P9P A;  3AI9 X;  3L8U A;  4JWF A;  5GM8 A;  4YQC A;  4IG6 A;  4YPZ A;  5GMB A;  4YQP A;  1UAK A;  4JWJ A;  2V3K A;  4YQO A;  4YVH A;  2I6D A;  3KY7 A;  3DCM X;  4YVG A;  3AXZ A;  2CX8 A;  4YVI A;  1Z85 A;  3E5Y A;  1VH0 A;  2Z0Y A;  1NXZ A;  1X7O A;  3IC6 A;  4JWH A;  4YQS A;  1NS5 A;  1V2X A;  5FAI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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