1LW6I

Crystal structure of the complex of subtilisin bpn' with chymotrypsin inhibitor 2 at 1.5 angstrom resolution
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
63
structure length
63
Chain Sequence
KTEWPELVGKSVEEAKKVILQDKPAAQIIVLPVGTIVTMEYRIDRVRLFVDKLDNIAQVPRVG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A clogged gutter mechanism for protease inhibitors.
pubmed doi rcsb
molecule keywords SUBTILISIN BPN'
molecule tags Hydrolase
source organism Bacillus amyloliquefaciens
total genus 16
structure length 63
sequence length 63
ec nomenclature
pdb deposition date 2002-05-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00280 potato_inhibit Potato inhibitor I family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.10.10 Alpha Beta 2-Layer Sandwich Trypsin Inhibitor V; Chain A Trypsin Inhibitor V, subunit A 1lw6I00
1HYMA 4B1TB 1TINA 1COAI 1TM1I 1CSEI 1TM4I 2SECI 1TMGI 2SNII 4B2BB 1Y3CI 3RDZC 1CISA 1TM3I 2CI2I 1EGLA 1Y3FI 4B2CB 1TO2I 2TECI 1Y3DI 1SBNI 1LW6I 1Y4DI 1Y34I 1YPBI 3TECI 3CI2A 1MEEI 1TECI 1TO1I 1YPAI 1TM7I 1DWMA 1Y33I 5FBZB 1SIBI 4B2AB 1TM5I 1Y1KI 4H4FB 1VBWA 5FFNI 3W0DA 1Y3BI 1Y4AI 1Y48I 1YPCI 3RDYA 1ACBI 1MITA 3W0EA
chains in the Genus database with same CATH superfamily
1HYMA 4B1TB 1TINA 1COAI 1TM1I 1CSEI 1TM4I 2SECI 5E10A 2KUEA 2KUDA 1TMGI 2SNII 4B2BB 1Y3CI 3RDZC 1CISA 1TM3I 2CI2I 1EGLA 5E0ZA 1Y3FI 4B2CB 1TO2I 2TECI 1Y3DI 1SBNI 1LW6I 1Y4DI 1Y34I 1YPBI 3TECI 3CI2A 1MEEI 1TECI 1TO1I 1YPAI 3M9GA 1TM7I 1DWMA 1Y33I 5FBZB 1SIBI 2KUFA 4B2AB 2KUIA 1TM5I 1Y1KI 4H4FB 1VBWA 5E0YA 5FFNI 3W0DA 1Y3BI 1Y4AI 3OUVA 3PY9A 1Y48I 1YPCI 3RDYA 1ACBI 1MITA 2MGVA 3W0EA
chains in the Genus database with same CATH topology
1HYMA 4B1TB 1TINA 1COAI 1TM1I 1CSEI 1TM4I 2SECI 1TMGI 2SNII 4B2BB 1Y3CI 3RDZC 1CISA 1TM3I 2CI2I 1EGLA 1Y3FI 4B2CB 1TO2I 2TECI 1Y3DI 1SBNI 1LW6I 1Y4DI 1Y34I 1YPBI 3TECI 3CI2A 1MEEI 1TECI 1TO1I 1YPAI 1TM7I 1DWMA 1Y33I 5FBZB 1SIBI 4B2AB 1TM5I 1Y1KI 4H4FB 1VBWA 5FFNI 3W0DA 1Y3BI 1Y4AI 1Y48I 1YPCI 3RDYA 1ACBI 1MITA 3W0EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HYM A;  4B1T B;  1TIN A;  1COA I;  1TM1 I;  1CSE I;  1TM4 I;  2SEC I;  1TMG I;  2SNI I;  4B2B B;  1Y3C I;  3RDZ C;  1CIS A;  1TM3 I;  2CI2 I;  1EGL A;  1Y3F I;  4B2C B;  1TO2 I;  2TEC I;  1Y3D I;  1SBN I;  1LW6 I;  1Y4D I;  1Y34 I;  1YPB I;  3TEC I;  3CI2 A;  1MEE I;  1TEC I;  1TO1 I;  1YPA I;  1TM7 I;  1DWM A;  1Y33 I;  5FBZ B;  1SIB I;  4B2A B;  1TM5 I;  1Y1K I;  4H4F B;  1VBW A;  5FFN I;  3W0D A;  1Y3B I;  1Y4A I;  1Y48 I;  1YPC I;  3RDY A;  1ACB I;  1MIT A;  3W0E A; 
#chains in the Genus database with same CATH topology
 1HYM A;  4B1T B;  1TIN A;  1COA I;  1TM1 I;  1CSE I;  1TM4 I;  2SEC I;  5E10 A;  2KUE A;  2KUD A;  1TMG I;  2SNI I;  4B2B B;  1Y3C I;  3RDZ C;  1CIS A;  1TM3 I;  2CI2 I;  1EGL A;  5E0Z A;  1Y3F I;  4B2C B;  1TO2 I;  2TEC I;  1Y3D I;  1SBN I;  1LW6 I;  1Y4D I;  1Y34 I;  1YPB I;  3TEC I;  3CI2 A;  1MEE I;  1TEC I;  1TO1 I;  1YPA I;  3M9G A;  1TM7 I;  1DWM A;  1Y33 I;  5FBZ B;  1SIB I;  2KUF A;  4B2A B;  2KUI A;  1TM5 I;  1Y1K I;  4H4F B;  1VBW A;  5E0Y A;  5FFN I;  3W0D A;  1Y3B I;  1Y4A I;  3OUV A;  3PY9 A;  1Y48 I;  1YPC I;  3RDY A;  1ACB I;  1MIT A;  2MGV A;  3W0E A; 
#chains in the Genus database with same CATH homology
 1HYM A;  4B1T B;  1TIN A;  1COA I;  1TM1 I;  1CSE I;  1TM4 I;  2SEC I;  1TMG I;  2SNI I;  4B2B B;  1Y3C I;  3RDZ C;  1CIS A;  1TM3 I;  2CI2 I;  1EGL A;  1Y3F I;  4B2C B;  1TO2 I;  2TEC I;  1Y3D I;  1SBN I;  1LW6 I;  1Y4D I;  1Y34 I;  1YPB I;  3TEC I;  3CI2 A;  1MEE I;  1TEC I;  1TO1 I;  1YPA I;  1TM7 I;  1DWM A;  1Y33 I;  5FBZ B;  1SIB I;  4B2A B;  1TM5 I;  1Y1K I;  4H4F B;  1VBW A;  5FFN I;  3W0D A;  1Y3B I;  1Y4A I;  1Y48 I;  1YPC I;  3RDY A;  1ACB I;  1MIT A;  3W0E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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