1NA6A

Crystal structure of restriction endonuclease ecorii mutant r88a
Total Genus 101

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
395
structure length
365
Chain Sequence
SVFHNWLLEIACENYFVYIKRLSANDTGATQVGLYIPSGIVEKLFPSINHTRELNPSVFLTAHVSSHDCPDSEARAIYYNSAHFGKTRNEKRITRWGRGSPLQDPENTGALTLLAFKLDEQGGDCKEVNIWVCASTDEEDVIETAIGEVIPGALISGPAGQILGGLSLQQAPVNHKYILPEDWHLRFPSGSEIIQYAASHYDPDEQLLDRRRVEYDIFLLVEELHVLDIIRKGFGSVDEFIALANSVSNRRKSRAGKSLELHLEHLFIEHGLRHFATQAPDFLFPSAGAYHPLRMLAVKTTCKDRWRQILNHLFTLQEGVSLAQYREMRESGVRLVVPSSLHKKYPEAVRAELMTLGAFIAELTG
5010015020025030035035030025020015010050
020406080100Genus Matrix

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
AH1 (4-15)S5 (116-123)S7 (159-164)EMPTYTII3 (156-159)S1 (18-25)TIV1 (31-37)TI5 (111-114)TII1 (103-106)TIV5 (89-92)AH3 (44-50)TI6 (125-128)TI1 (51-54)S3 (75-85)TI2 (52-55)TIV2 (57-60)TIV4 (71-74)S2 (63-70)S4 (96-100)TI3 (70-73)S8 (322-324)3H2 (107-109)TI4 (110-113)S6 (133-138)TII2 (113-116)AH4 (142-152)AH5 (165-168)TI10 (189-192)TI7 (186-189)TI9 (188-191)TI8 (187-190)AH6 (196-204)AH9 (269-280)AH8 (248-265)TIV6 (266-269)O1 (281-283)TIV7 (288-298)AH10 (355-362)3H3 (305-308)TIV8 (289-299)TVIb1 (301-304)3H4 (332-334)TVIII1 (324-327)TII4 (327-330)AH2 (27-30)TIV3 (59-62)3H1 (87-89)AH7 (214-243)S9 (346-348)TIV9 (362-365)Updating...
connected with : NaN
molecule tags Hydrolase
source organism Escherichia coli
publication title Crystal structure of type IIE restriction endonuclease EcoRII reveals an autoinhibition mechanism by a novel effector-binding fold.
pubmed doi rcsb
molecule keywords Restriction endonuclease EcoRII
total genus 101
structure length 365
sequence length 395
chains with identical sequence B
ec nomenclature ec 3.1.21.4: Type II site-specific deoxyribonuclease.
pdb deposition date 2002-11-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09019 EcoRII-C EcoRII C terminal
A PF09217 EcoRII-N Restriction endonuclease EcoRII, N-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.330.10 Mainly Beta Beta Barrel At1g16640 B3 domain DNA-binding pseudobarrel domain 1na6A01
4LDVA 4I1KA 1YELA 4LDWA 3HQFA 1NA6A 4LDUA 4LDYA 1WIDA 4LDXA
chains in the Genus database with same CATH superfamily
4LDVA 3ZI5A 1YELA 4I1KA 4LDYA 1N0EA 2C1LA 4LDWA 3HQFA 1NA6A 1N0GA 1N0FA 4LDUA 1WIDA 4LDXA
chains in the Genus database with same CATH topology
4LDVA 4I1KA 1YELA 4LDWA 3HQFA 1NA6A 4LDUA 4LDYA 1WIDA 4LDXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LDV A;  4I1K A;  1YEL A;  4LDW A;  3HQF A;  1NA6 A;  4LDU A;  4LDY A;  1WID A;  4LDX A; 
#chains in the Genus database with same CATH topology
 4LDV A;  3ZI5 A;  1YEL A;  4I1K A;  4LDY A;  1N0E A;  2C1L A;  4LDW A;  3HQF A;  1NA6 A;  1N0G A;  1N0F A;  4LDU A;  1WID A;  4LDX A; 
#chains in the Genus database with same CATH homology
 4LDV A;  4I1K A;  1YEL A;  4LDW A;  3HQF A;  1NA6 A;  4LDU A;  4LDY A;  1WID A;  4LDX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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