1NMKA

The sanglifehrin-cyclophilin interaction: degradation work, synthetic macrocyclic analogues, x-ray crystal structure and binding data
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
165
structure length
165
Chain Sequence
MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Sanglifehrin-Cyclophilin Interaction: Degradation Work, Synthetic Macrocyclic Analogues, X-ray Crystal Structure and Binding Data
pubmed doi rcsb
molecule tags Isomerase
source organism Homo sapiens
molecule keywords Peptidyl-prolyl cis-trans isomerase A
total genus 48
structure length 165
sequence length 165
chains with identical sequence B
ec nomenclature ec 5.2.1.8: Peptidylprolyl isomerase.
pdb deposition date 2003-01-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00160 Pro_isomerase Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.100.10 Mainly Beta Beta Barrel Cyclophilin Cyclophilin-like 1nmkA00
1CWLA 4E1QA 2HE9A 1VAIA 1X7FA 2XGYB 4FRUA 5CBUA 1IHGA 3RFYA 4ZSCA 2IGVA 1M9EA 3BO7A 2K7NA 2WFIA 1CWOA 2X2AA 4DGBA 4CYHA 3ODIA 4EYVA 1VBTA 3R4GA 2WLWA 3MMLA 1V9TA 3R59A 5CCNA 2PHCB 2ALFA 3RCGA 3K0NA 4J59A 1VBSA 1AWUA 2A2NA 2C3BA 1AWTA 4DGCA 3CYSA 1MZWA 1QOIA 2PLUA 1E3BA 3ODLA 4YUJA 5KV3A 1H0PA 1M9XA 4R3EA 4DGAA 4YUNA 4J58A 2POEA 5KUSA 2BITX 2CFEA 4N1NA 1AK4A 3JB9d 3UCHA 2CK1A 3RCFA 4N1SA 1CLHA 2B71A 1M9CA 1M63C 4YULA 3O7TA 4YUKA 1XQ7A 5KUWA 4I9YA 1RMHA 1ZMFA 4O8HA 1ZKFA 5KUUA 2N0TA 2X7KA 2MC9A 3EOVA 2OJUA 2CPLA 5CYHA 3R56A 1MF8C 1CWKA 2FU0A 5CBVA 2MS4A 4N1QA 4JJMA 4ZSDA 1CWHA 2ZP2A 1DYWA 2RS4A 3K0PA 4S1JA 3QYUA 5F66A 4YUMA 5KV7A 5KUNA 1W8VA 1C5FA 4YUHA 5KV4A 3RDAX 1CWCA 1AWVA 5JHEA 1CWBA 3T1UA 1AWRA 5CCQA 4N1MA 1QNHA 4R3FA 3RCIX 5KUQA 2HQJA 4LQWA 1AWQA 1VDNA 2GW2A 4DGDA 1OCAA 4J5CX 2X83B 3K0MA 1LOPA 4FRVA 5A0EA 1CWIA 4J5DX 1ISTA 1J2AA 5LUDA 3CYHA 2WFJA 5KV2A 1FGLA 1A33A 1CWJA 4HY7A 1CYNA 5KURA 5CCSX 1M9DA 4YUOA 1Z81A 4YUIA 5CCRA 4O8IA 1NMKA 2X2CK 5KUVA 3R57A 4S1EA 2Z6WA 1IIPA 1M9FA 1ZKCA 2MZUA 2QERA 2ESLA 2X25B 1M9YA 3OREA 4N1OA 5DUDA 4J5BA 2RMCA 5KULA 1AWSA 3K0OA 3OPFA 5KV6A 4N1RA 2R99A 1CWAA 5KV0A 5KUOA 2CYHA 5KV5A 4YUPA 5KV1A 3RCKX 3RDDA 1E8KA 1W74A 1W8MA 3OEPA 5KUZA 3ICIA 4YUGA 1A58A 2HQ6A 2OSEA 3RDBA 3VA7A 2HAQA 2IGWA 2P0OA 2NULA 3K2CA 3K0QA 4TOTA 4DGEA 5CBTA 1MIKA 1XYHA 4J5EX 4J5AX 2RMBA 3RCLA 2CMTA 2X2DB 1W8LA 3BT8A 3R49A 1YNDA 2OK3A 2POYA 3MMLB 1XWNA 1BCKA 3ICHA 3K0RA 2RMAA 4JCPA 4XNCA 3S6MA 3PMPA 3RD9X 4IPZA 1CWFA 3R54A 3BKPA 1CWMA 1XO7A 2MVZA 4N1PA 5CBWA 2BIUX 3RDCA 1QNGA
chains in the Genus database with same CATH superfamily
1CWLA 4E1QA 2HE9A 1VAIA 1X7FA 2XGYB 4FRUA 5CBUA 1IHGA 3RFYA 4ZSCA 2IGVA 1M9EA 3BO7A 2K7NA 2WFIA 1CWOA 2X2AA 4DGBA 4CYHA 3ODIA 4EYVA 1VBTA 3R4GA 2WLWA 3MMLA 1V9TA 3R59A 5CCNA 2PHCB 2ALFA 3RCGA 3X27A 3K0NA 4J59A 1VBSA 1AWUA 2A2NA 2C3BA 1AWTA 4DGCA 3CYSA 1MZWA 1QOIA 2PLUA 1E3BA 3ODLA 4YUJA 5KV3A 1H0PA 1M9XA 4R3EA 4DGAA 2KA0A 4J58A 4YUNA 2POEA 5KUSA 2BITX 2CFEA 4N1NA 1AK4A 3JB9d 3UCHA 2CK1A 3RCFA 4N1SA 1CLHA 2B71A 1M9CA 1M63C 4YULA 3O7TA 4YUKA 1XQ7A 5KUWA 4I9YA 1RMHA 1ZMFA 4O8HA 1ZKFA 5KUUA 2N0TA 2X7KA 2MC9A 3EOVA 2NNZA 2OJUA 2CPLA 5CYHA 3R56A 1MF8C 1CWKA 2FU0A 5CBVA 2MS4A 4N1QA 4JJMA 4ZSDA 1CWHA 2ZP2A 1DYWA 2RS4A 3K0PA 4S1JA 3QYUA 5F66A 4YUMA 5KV7A 5KUNA 1W8VA 1C5FA 4YUHA 5KV4A 3RDAX 1CWCA 1AWVA 5JHEA 1CWBA 3T1UA 1AWRA 5CCQA 4N1MA 1QNHA 4R3FA 3RCIX 5KUQA 2HQJA 4LQWA 1AWQA 1VDNA 2GW2A 4DGDA 1OCAA 4J5CX 2X83B 3K0MA 1LOPA 4FRVA 5A0EA 1CWIA 4J5DX 1ISTA 1J2AA 5LUDA 3CYHA 2WFJA 5KV2A 1FGLA 1A33A 1CWJA 3KOPA 1CYNA 4HY7A 5KURA 5CCSX 1M9DA 4YUOA 1Z81A 4YUIA 5CCRA 4O8IA 1NMKA 2X2CK 5KUVA 3R57A 4S1EA 2Z6WA 1IIPA 1M9FA 1ZKCA 2MZUA 2QERA 2ESLA 2X25B 1M9YA 3OREA 4N1OA 5DUDA 4J5BA 2RMCA 5KULA 1AWSA 3K0OA 3OPFA 5KV6A 4N1RA 2R99A 1CWAA 5KV0A 5KUOA 2CYHA 5KV5A 4YUPA 5KV1A 3RCKX 3RDDA 1E8KA 1W74A 1W8MA 3OEPA 5KUZA 3ICIA 4YUGA 1A58A 2HQ6A 2OSEA 3RDBA 3VA7A 2HAQA 2IGWA 2P0OA 2NULA 3K2CA 3K0QA 4TOTA 4DGEA 5CBTA 1MIKA 1XYHA 4J5EX 4J5AX 2RMBA 3RCLA 2CMTA 2X2DB 1W8LA 3BT8A 3R49A 1YNDA 2OK3A 2POYA 3MMLB 1XWNA 1BCKA 3ICHA 3K0RA 2RMAA 4JCPA 4XNCA 3S6MA 3PMPA 3RD9X 4IPZA 1CWFA 3R54A 3BKPA 1CWMA 1XO7A 2MVZA 4N1PA 5CBWA 2BIUX 1ZX8A 3RDCA 1QNGA
chains in the Genus database with same CATH topology
1CWLA 4E1QA 2HE9A 1VAIA 1X7FA 2XGYB 4FRUA 5CBUA 1IHGA 3RFYA 4ZSCA 2IGVA 1M9EA 3BO7A 2K7NA 2WFIA 1CWOA 2X2AA 4DGBA 4CYHA 3ODIA 4EYVA 1VBTA 3R4GA 2WLWA 3MMLA 1V9TA 3R59A 5CCNA 2PHCB 2ALFA 3RCGA 3K0NA 4J59A 1VBSA 1AWUA 2A2NA 2C3BA 1AWTA 4DGCA 3CYSA 1MZWA 1QOIA 2PLUA 1E3BA 3ODLA 4YUJA 5KV3A 1H0PA 1M9XA 4R3EA 4DGAA 4YUNA 4J58A 2POEA 5KUSA 2BITX 2CFEA 4N1NA 1AK4A 3JB9d 3UCHA 2CK1A 3RCFA 4N1SA 1CLHA 2B71A 1M9CA 1M63C 4YULA 3O7TA 4YUKA 1XQ7A 5KUWA 4I9YA 1RMHA 1ZMFA 4O8HA 1ZKFA 5KUUA 2N0TA 2X7KA 2MC9A 3EOVA 2OJUA 2CPLA 5CYHA 3R56A 1MF8C 1CWKA 2FU0A 5CBVA 2MS4A 4N1QA 4JJMA 4ZSDA 1CWHA 2ZP2A 1DYWA 2RS4A 3K0PA 4S1JA 3QYUA 5F66A 4YUMA 5KV7A 5KUNA 1W8VA 1C5FA 4YUHA 5KV4A 3RDAX 1CWCA 1AWVA 5JHEA 1CWBA 3T1UA 1AWRA 5CCQA 4N1MA 1QNHA 4R3FA 3RCIX 5KUQA 2HQJA 4LQWA 1AWQA 1VDNA 2GW2A 4DGDA 1OCAA 4J5CX 2X83B 3K0MA 1LOPA 4FRVA 5A0EA 1CWIA 4J5DX 1ISTA 1J2AA 5LUDA 3CYHA 2WFJA 5KV2A 1FGLA 1A33A 1CWJA 4HY7A 1CYNA 5KURA 5CCSX 1M9DA 4YUOA 1Z81A 4YUIA 5CCRA 4O8IA 1NMKA 2X2CK 5KUVA 3R57A 4S1EA 2Z6WA 1IIPA 1M9FA 1ZKCA 2MZUA 2QERA 2ESLA 2X25B 1M9YA 3OREA 4N1OA 5DUDA 4J5BA 2RMCA 5KULA 1AWSA 3K0OA 3OPFA 5KV6A 4N1RA 2R99A 1CWAA 5KV0A 5KUOA 2CYHA 5KV5A 4YUPA 5KV1A 3RCKX 3RDDA 1E8KA 1W74A 1W8MA 3OEPA 5KUZA 3ICIA 4YUGA 1A58A 2HQ6A 2OSEA 3RDBA 3VA7A 2HAQA 2IGWA 2P0OA 2NULA 3K2CA 3K0QA 4TOTA 4DGEA 5CBTA 1MIKA 1XYHA 4J5EX 4J5AX 2RMBA 3RCLA 2CMTA 2X2DB 1W8LA 3BT8A 3R49A 1YNDA 2OK3A 2POYA 3MMLB 1XWNA 1BCKA 3ICHA 3K0RA 2RMAA 4JCPA 4XNCA 3S6MA 3PMPA 3RD9X 4IPZA 1CWFA 3R54A 3BKPA 1CWMA 1XO7A 2MVZA 4N1PA 5CBWA 2BIUX 3RDCA 1QNGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1CWL A;  4E1Q A;  2HE9 A;  1VAI A;  1X7F A;  2XGY B;  4FRU A;  5CBU A;  1IHG A;  3RFY A;  4ZSC A;  2IGV A;  1M9E A;  3BO7 A;  2K7N A;  2WFI A;  1CWO A;  2X2A A;  4DGB A;  4CYH A;  3ODI A;  4EYV A;  1VBT A;  3R4G A;  2WLW A;  3MML A;  1V9T A;  3R59 A;  5CCN A;  2PHC B;  2ALF A;  3RCG A;  3K0N A;  4J59 A;  1VBS A;  1AWU A;  2A2N A;  2C3B A;  1AWT A;  4DGC A;  3CYS A;  1MZW A;  1QOI A;  2PLU A;  1E3B A;  3ODL A;  4YUJ A;  5KV3 A;  1H0P A;  1M9X A;  4R3E A;  4DGA A;  4YUN A;  4J58 A;  2POE A;  5KUS A;  2BIT X;  2CFE A;  4N1N A;  1AK4 A;  3JB9 d;  3UCH A;  2CK1 A;  3RCF A;  4N1S A;  1CLH A;  2B71 A;  1M9C A;  1M63 C;  4YUL A;  3O7T A;  4YUK A;  1XQ7 A;  5KUW A;  4I9Y A;  1RMH A;  1ZMF A;  4O8H A;  1ZKF A;  5KUU A;  2N0T A;  2X7K A;  2MC9 A;  3EOV A;  2OJU A;  2CPL A;  5CYH A;  3R56 A;  1MF8 C;  1CWK A;  2FU0 A;  5CBV A;  2MS4 A;  4N1Q A;  4JJM A;  4ZSD A;  1CWH A;  2ZP2 A;  1DYW A;  2RS4 A;  3K0P A;  4S1J A;  3QYU A;  5F66 A;  4YUM A;  5KV7 A;  5KUN A;  1W8V A;  1C5F A;  4YUH A;  5KV4 A;  3RDA X;  1CWC A;  1AWV A;  5JHE A;  1CWB A;  3T1U A;  1AWR A;  5CCQ A;  4N1M A;  1QNH A;  4R3F A;  3RCI X;  5KUQ A;  2HQJ A;  4LQW A;  1AWQ A;  1VDN A;  2GW2 A;  4DGD A;  1OCA A;  4J5C X;  2X83 B;  3K0M A;  1LOP A;  4FRV A;  5A0E A;  1CWI A;  4J5D X;  1IST A;  1J2A A;  5LUD A;  3CYH A;  2WFJ A;  5KV2 A;  1FGL A;  1A33 A;  1CWJ A;  4HY7 A;  1CYN A;  5KUR A;  5CCS X;  1M9D A;  4YUO A;  1Z81 A;  4YUI A;  5CCR A;  4O8I A;  1NMK A;  2X2C K;  5KUV A;  3R57 A;  4S1E A;  2Z6W A;  1IIP A;  1M9F A;  1ZKC A;  2MZU A;  2QER A;  2ESL A;  2X25 B;  1M9Y A;  3ORE A;  4N1O A;  5DUD A;  4J5B A;  2RMC A;  5KUL A;  1AWS A;  3K0O A;  3OPF A;  5KV6 A;  4N1R A;  2R99 A;  1CWA A;  5KV0 A;  5KUO A;  2CYH A;  5KV5 A;  4YUP A;  5KV1 A;  3RCK X;  3RDD A;  1E8K A;  1W74 A;  1W8M A;  3OEP A;  5KUZ A;  3ICI A;  4YUG A;  1A58 A;  2HQ6 A;  2OSE A;  3RDB A;  3VA7 A;  2HAQ A;  2IGW A;  2P0O A;  2NUL A;  3K2C A;  3K0Q A;  4TOT A;  4DGE A;  5CBT A;  1MIK A;  1XYH A;  4J5E X;  4J5A X;  2RMB A;  3RCL A;  2CMT A;  2X2D B;  1W8L A;  3BT8 A;  3R49 A;  1YND A;  2OK3 A;  2POY A;  3MML B;  1XWN A;  1BCK A;  3ICH A;  3K0R A;  2RMA A;  4JCP A;  4XNC A;  3S6M A;  3PMP A;  3RD9 X;  4IPZ A;  1CWF A;  3R54 A;  3BKP A;  1CWM A;  1XO7 A;  2MVZ A;  4N1P A;  5CBW A;  2BIU X;  3RDC A;  1QNG A; 
#chains in the Genus database with same CATH topology
 1CWL A;  4E1Q A;  2HE9 A;  1VAI A;  1X7F A;  2XGY B;  4FRU A;  5CBU A;  1IHG A;  3RFY A;  4ZSC A;  2IGV A;  1M9E A;  3BO7 A;  2K7N A;  2WFI A;  1CWO A;  2X2A A;  4DGB A;  4CYH A;  3ODI A;  4EYV A;  1VBT A;  3R4G A;  2WLW A;  3MML A;  1V9T A;  3R59 A;  5CCN A;  2PHC B;  2ALF A;  3RCG A;  3X27 A;  3K0N A;  4J59 A;  1VBS A;  1AWU A;  2A2N A;  2C3B A;  1AWT A;  4DGC A;  3CYS A;  1MZW A;  1QOI A;  2PLU A;  1E3B A;  3ODL A;  4YUJ A;  5KV3 A;  1H0P A;  1M9X A;  4R3E A;  4DGA A;  2KA0 A;  4J58 A;  4YUN A;  2POE A;  5KUS A;  2BIT X;  2CFE A;  4N1N A;  1AK4 A;  3JB9 d;  3UCH A;  2CK1 A;  3RCF A;  4N1S A;  1CLH A;  2B71 A;  1M9C A;  1M63 C;  4YUL A;  3O7T A;  4YUK A;  1XQ7 A;  5KUW A;  4I9Y A;  1RMH A;  1ZMF A;  4O8H A;  1ZKF A;  5KUU A;  2N0T A;  2X7K A;  2MC9 A;  3EOV A;  2NNZ A;  2OJU A;  2CPL A;  5CYH A;  3R56 A;  1MF8 C;  1CWK A;  2FU0 A;  5CBV A;  2MS4 A;  4N1Q A;  4JJM A;  4ZSD A;  1CWH A;  2ZP2 A;  1DYW A;  2RS4 A;  3K0P A;  4S1J A;  3QYU A;  5F66 A;  4YUM A;  5KV7 A;  5KUN A;  1W8V A;  1C5F A;  4YUH A;  5KV4 A;  3RDA X;  1CWC A;  1AWV A;  5JHE A;  1CWB A;  3T1U A;  1AWR A;  5CCQ A;  4N1M A;  1QNH A;  4R3F A;  3RCI X;  5KUQ A;  2HQJ A;  4LQW A;  1AWQ A;  1VDN A;  2GW2 A;  4DGD A;  1OCA A;  4J5C X;  2X83 B;  3K0M A;  1LOP A;  4FRV A;  5A0E A;  1CWI A;  4J5D X;  1IST A;  1J2A A;  5LUD A;  3CYH A;  2WFJ A;  5KV2 A;  1FGL A;  1A33 A;  1CWJ A;  3KOP A;  1CYN A;  4HY7 A;  5KUR A;  5CCS X;  1M9D A;  4YUO A;  1Z81 A;  4YUI A;  5CCR A;  4O8I A;  1NMK A;  2X2C K;  5KUV A;  3R57 A;  4S1E A;  2Z6W A;  1IIP A;  1M9F A;  1ZKC A;  2MZU A;  2QER A;  2ESL A;  2X25 B;  1M9Y A;  3ORE A;  4N1O A;  5DUD A;  4J5B A;  2RMC A;  5KUL A;  1AWS A;  3K0O A;  3OPF A;  5KV6 A;  4N1R A;  2R99 A;  1CWA A;  5KV0 A;  5KUO A;  2CYH A;  5KV5 A;  4YUP A;  5KV1 A;  3RCK X;  3RDD A;  1E8K A;  1W74 A;  1W8M A;  3OEP A;  5KUZ A;  3ICI A;  4YUG A;  1A58 A;  2HQ6 A;  2OSE A;  3RDB A;  3VA7 A;  2HAQ A;  2IGW A;  2P0O A;  2NUL A;  3K2C A;  3K0Q A;  4TOT A;  4DGE A;  5CBT A;  1MIK A;  1XYH A;  4J5E X;  4J5A X;  2RMB A;  3RCL A;  2CMT A;  2X2D B;  1W8L A;  3BT8 A;  3R49 A;  1YND A;  2OK3 A;  2POY A;  3MML B;  1XWN A;  1BCK A;  3ICH A;  3K0R A;  2RMA A;  4JCP A;  4XNC A;  3S6M A;  3PMP A;  3RD9 X;  4IPZ A;  1CWF A;  3R54 A;  3BKP A;  1CWM A;  1XO7 A;  2MVZ A;  4N1P A;  5CBW A;  2BIU X;  1ZX8 A;  3RDC A;  1QNG A; 
#chains in the Genus database with same CATH homology
 1CWL A;  4E1Q A;  2HE9 A;  1VAI A;  1X7F A;  2XGY B;  4FRU A;  5CBU A;  1IHG A;  3RFY A;  4ZSC A;  2IGV A;  1M9E A;  3BO7 A;  2K7N A;  2WFI A;  1CWO A;  2X2A A;  4DGB A;  4CYH A;  3ODI A;  4EYV A;  1VBT A;  3R4G A;  2WLW A;  3MML A;  1V9T A;  3R59 A;  5CCN A;  2PHC B;  2ALF A;  3RCG A;  3K0N A;  4J59 A;  1VBS A;  1AWU A;  2A2N A;  2C3B A;  1AWT A;  4DGC A;  3CYS A;  1MZW A;  1QOI A;  2PLU A;  1E3B A;  3ODL A;  4YUJ A;  5KV3 A;  1H0P A;  1M9X A;  4R3E A;  4DGA A;  4YUN A;  4J58 A;  2POE A;  5KUS A;  2BIT X;  2CFE A;  4N1N A;  1AK4 A;  3JB9 d;  3UCH A;  2CK1 A;  3RCF A;  4N1S A;  1CLH A;  2B71 A;  1M9C A;  1M63 C;  4YUL A;  3O7T A;  4YUK A;  1XQ7 A;  5KUW A;  4I9Y A;  1RMH A;  1ZMF A;  4O8H A;  1ZKF A;  5KUU A;  2N0T A;  2X7K A;  2MC9 A;  3EOV A;  2OJU A;  2CPL A;  5CYH A;  3R56 A;  1MF8 C;  1CWK A;  2FU0 A;  5CBV A;  2MS4 A;  4N1Q A;  4JJM A;  4ZSD A;  1CWH A;  2ZP2 A;  1DYW A;  2RS4 A;  3K0P A;  4S1J A;  3QYU A;  5F66 A;  4YUM A;  5KV7 A;  5KUN A;  1W8V A;  1C5F A;  4YUH A;  5KV4 A;  3RDA X;  1CWC A;  1AWV A;  5JHE A;  1CWB A;  3T1U A;  1AWR A;  5CCQ A;  4N1M A;  1QNH A;  4R3F A;  3RCI X;  5KUQ A;  2HQJ A;  4LQW A;  1AWQ A;  1VDN A;  2GW2 A;  4DGD A;  1OCA A;  4J5C X;  2X83 B;  3K0M A;  1LOP A;  4FRV A;  5A0E A;  1CWI A;  4J5D X;  1IST A;  1J2A A;  5LUD A;  3CYH A;  2WFJ A;  5KV2 A;  1FGL A;  1A33 A;  1CWJ A;  4HY7 A;  1CYN A;  5KUR A;  5CCS X;  1M9D A;  4YUO A;  1Z81 A;  4YUI A;  5CCR A;  4O8I A;  1NMK A;  2X2C K;  5KUV A;  3R57 A;  4S1E A;  2Z6W A;  1IIP A;  1M9F A;  1ZKC A;  2MZU A;  2QER A;  2ESL A;  2X25 B;  1M9Y A;  3ORE A;  4N1O A;  5DUD A;  4J5B A;  2RMC A;  5KUL A;  1AWS A;  3K0O A;  3OPF A;  5KV6 A;  4N1R A;  2R99 A;  1CWA A;  5KV0 A;  5KUO A;  2CYH A;  5KV5 A;  4YUP A;  5KV1 A;  3RCK X;  3RDD A;  1E8K A;  1W74 A;  1W8M A;  3OEP A;  5KUZ A;  3ICI A;  4YUG A;  1A58 A;  2HQ6 A;  2OSE A;  3RDB A;  3VA7 A;  2HAQ A;  2IGW A;  2P0O A;  2NUL A;  3K2C A;  3K0Q A;  4TOT A;  4DGE A;  5CBT A;  1MIK A;  1XYH A;  4J5E X;  4J5A X;  2RMB A;  3RCL A;  2CMT A;  2X2D B;  1W8L A;  3BT8 A;  3R49 A;  1YND A;  2OK3 A;  2POY A;  3MML B;  1XWN A;  1BCK A;  3ICH A;  3K0R A;  2RMA A;  4JCP A;  4XNC A;  3S6M A;  3PMP A;  3RD9 X;  4IPZ A;  1CWF A;  3R54 A;  3BKP A;  1CWM A;  1XO7 A;  2MVZ A;  4N1P A;  5CBW A;  2BIU X;  3RDC A;  1QNG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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