1PE31

Solution structure of the disulphide-linked dimer of human intestinal trefoil factor (tff3)
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
59
structure length
59
Chain Sequence
EEYVGLSANQCAVPAKDRVDCGYPHVTPKECNNRGCCFDSRIPGVPWCFKPLQEAECTF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the disulfide-linked dimer of human intestinal trefoil factor (TFF3): the intermolecular orientation and interactions are markedly different from those of other dimeric trefoil proteins.
pubmed doi rcsb
molecule keywords Trefoil factor 3
molecule tags Cell cycle
source organism Homo sapiens
total genus 6
structure length 59
sequence length 59
chains with identical sequence 2
ec nomenclature
pdb deposition date 2003-05-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
1 PF00088 Trefoil Trefoil (P-type) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.110.10 Few Secondary Structures Irregular Spasmolytic Protein; domain 1 Spasmolytic Protein, domain 1 1pe3100
3TONA 3L4XA 3LPPA 2PSPA 3L4TA 3LPOA 1HI7A 3L4WA 1E9TA 1PE31 3L4ZA 1PSPA 2QMJA 2QLYA 1PCPA 3L4YA 1PS2A 3CTTA 3TOPA 3L4UA 3L4VA
chains in the Genus database with same CATH superfamily
3TONA 3L4XA 3LPPA 2PSPA 3L4TA 3LPOA 1HI7A 3L4WA 1E9TA 1PE31 3L4ZA 1PSPA 2QMJA 2QLYA 1PCPA 3L4YA 1PS2A 3CTTA 3TOPA 3L4UA 1XU6A 3L4VA
chains in the Genus database with same CATH topology
3TONA 3L4XA 3LPPA 2PSPA 3L4TA 3LPOA 1HI7A 3L4WA 1E9TA 1PE31 3L4ZA 1PSPA 2QMJA 2QLYA 1PCPA 3L4YA 1PS2A 3CTTA 3TOPA 3L4UA 3L4VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TON A;  3L4X A;  3LPP A;  2PSP A;  3L4T A;  3LPO A;  1HI7 A;  3L4W A;  1E9T A;  1PE3 1;  3L4Z A;  1PSP A;  2QMJ A;  2QLY A;  1PCP A;  3L4Y A;  1PS2 A;  3CTT A;  3TOP A;  3L4U A;  3L4V A; 
#chains in the Genus database with same CATH topology
 3TON A;  3L4X A;  3LPP A;  2PSP A;  3L4T A;  3LPO A;  1HI7 A;  3L4W A;  1E9T A;  1PE3 1;  3L4Z A;  1PSP A;  2QMJ A;  2QLY A;  1PCP A;  3L4Y A;  1PS2 A;  3CTT A;  3TOP A;  3L4U A;  1XU6 A;  3L4V A; 
#chains in the Genus database with same CATH homology
 3TON A;  3L4X A;  3LPP A;  2PSP A;  3L4T A;  3LPO A;  1HI7 A;  3L4W A;  1E9T A;  1PE3 1;  3L4Z A;  1PSP A;  2QMJ A;  2QLY A;  1PCP A;  3L4Y A;  1PS2 A;  3CTT A;  3TOP A;  3L4U A;  3L4V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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