1YI2D

Crystal structure of erythromycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
165
structure length
140
Chain Sequence
FHEMREPRIEKVVVHMGIGHANAEDILGEITGQMPVRTKAKRTVGEFDIREGDPIGAKVTLRDEMAEEFLQTALPLAELATSQFDDTGNFSFGLDVTVNLVRPGYRVAKRDKASRSIPTKHRLNPADAVAFIESTYDVEV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S Ribosomal RNA
total genus 22
structure length 140
sequence length 165
ec nomenclature
pdb deposition date 2005-01-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00281 Ribosomal_L5 Ribosomal protein L5
D PF00673 Ribosomal_L5_C ribosomal L5P family C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1440.10 Alpha Beta 2-Layer Sandwich 50s Ribosomal Protein L5; Chain: A, 50s Ribosomal Protein L5; Chain: A, 1yi2D00
5MLCG 2OTLD 3CC7D 1VQ7D 3PIPD 3CC4D 4IOCD 3CCMD 1JJ2D 1NJIF 1YJ9D 3CXCD 1QVGD 1M90F 3CCSD 3CCUD 3CC2D 2OTJD 3C9GA 1YJND 2NWUA 3I55D 1K73F 5DM7D 5GAEF 1W2BD 1VQ4D 5H1SH 3G4SD 3CMED 1MJIA 2ZJPD 3J7ZF 3CD6D 3DLLD 5HL7D 2OGKA 3OW2D 1VQMD 5DM6D 3G6ED 3CCQD 1IQ4A 1VQLD 5JVHD 1YJWD 4WF9D 1VQ6D 1YITD 1KD1F 1Q86F 1VQ5D 1Q7YF 1S72D 2QA4D 3CCJD 5JVGD 2ZJRD 4WFBD 4IO9D 1YIJD 1VQOD 3CCED 3CCRD 1VQPD 1K8AF 5GAGF 4UY8F 5GAHF 2NRQA 4WCED 1YHQD 2WNYA 4IOAD 2PZZA 1VQND 3D7AA 1KQSD 4U67D 3PIOD 1Q81F 3CMAD 3CCLD 5GADF 1VQKD 1N8RF 3CCVD 1K9MF 1M1KF 3I56D 1VQ8D 2ZJQD 1Q82F 3G71D 1YI2D 1QVFD 1VQ9D 2QEXD 3CF5D 3CPWD 4WFAD 4WFND 1KC8F
chains in the Genus database with same CATH superfamily
5MLCG 2OTLD 3CC7D 1VQ7D 3PIPD 3CC4D 4IOCD 3CCMD 1JJ2D 1NJIF 1YJ9D 3CXCD 1QVGD 1M90F 3CCSD 3CCUD 3CC2D 2OTJD 3C9GA 1YJND 2NWUA 3I55D 1K73F 5DM7D 5GAEF 1W2BD 1VQ4D 5H1SH 3G4SD 3CMED 1MJIA 2ZJPD 3J7ZF 3CD6D 3DLLD 5HL7D 2OGKA 3OW2D 1VQMD 5DM6D 3G6ED 3CCQD 1IQ4A 1VQLD 5JVHD 1YJWD 4WF9D 1VQ6D 1YITD 1KD1F 1Q86F 1VQ5D 1Q7YF 1S72D 2QA4D 3CCJD 5JVGD 2ZJRD 4WFBD 4IO9D 1YIJD 1VQOD 3CCED 3CCRD 1VQPD 1K8AF 5GAGF 4UY8F 5GAHF 2NRQA 4WCED 1YHQD 2WNYA 4IOAD 2PZZA 1VQND 3D7AA 1KQSD 4U67D 3PIOD 1Q81F 3CMAD 3CCLD 5GADF 1VQKD 1N8RF 3CCVD 1K9MF 1M1KF 3I56D 1VQ8D 2ZJQD 1Q82F 3G71D 1YI2D 1QVFD 1VQ9D 2QEXD 3CF5D 3CPWD 4WFAD 4WFND 1KC8F
chains in the Genus database with same CATH topology
5MLCG 2OTLD 3CC7D 1VQ7D 3PIPD 3CC4D 4IOCD 3CCMD 1JJ2D 1NJIF 1YJ9D 3CXCD 1QVGD 1M90F 3CCSD 3CCUD 3CC2D 2OTJD 3C9GA 1YJND 2NWUA 3I55D 1K73F 5DM7D 5GAEF 1W2BD 1VQ4D 5H1SH 3G4SD 3CMED 1MJIA 2ZJPD 3J7ZF 3CD6D 3DLLD 5HL7D 2OGKA 3OW2D 1VQMD 5DM6D 3G6ED 3CCQD 1IQ4A 1VQLD 5JVHD 1YJWD 4WF9D 1VQ6D 1YITD 1KD1F 1Q86F 1VQ5D 1Q7YF 1S72D 2QA4D 3CCJD 5JVGD 2ZJRD 4WFBD 4IO9D 1YIJD 1VQOD 3CCED 3CCRD 1VQPD 1K8AF 5GAGF 4UY8F 5GAHF 2NRQA 4WCED 1YHQD 2WNYA 4IOAD 2PZZA 1VQND 3D7AA 1KQSD 4U67D 3PIOD 1Q81F 3CMAD 3CCLD 5GADF 1VQKD 1N8RF 3CCVD 1K9MF 1M1KF 3I56D 1VQ8D 2ZJQD 1Q82F 3G71D 1YI2D 1QVFD 1VQ9D 2QEXD 3CF5D 3CPWD 4WFAD 4WFND 1KC8F
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5MLC G;  2OTL D;  3CC7 D;  1VQ7 D;  3PIP D;  3CC4 D;  4IOC D;  3CCM D;  1JJ2 D;  1NJI F;  1YJ9 D;  3CXC D;  1QVG D;  1M90 F;  3CCS D;  3CCU D;  3CC2 D;  2OTJ D;  3C9G A;  1YJN D;  2NWU A;  3I55 D;  1K73 F;  5DM7 D;  5GAE F;  1W2B D;  1VQ4 D;  5H1S H;  3G4S D;  3CME D;  1MJI A;  2ZJP D;  3J7Z F;  3CD6 D;  3DLL D;  5HL7 D;  2OGK A;  3OW2 D;  1VQM D;  5DM6 D;  3G6E D;  3CCQ D;  1IQ4 A;  1VQL D;  5JVH D;  1YJW D;  4WF9 D;  1VQ6 D;  1YIT D;  1KD1 F;  1Q86 F;  1VQ5 D;  1Q7Y F;  1S72 D;  2QA4 D;  3CCJ D;  5JVG D;  2ZJR D;  4WFB D;  4IO9 D;  1YIJ D;  1VQO D;  3CCE D;  3CCR D;  1VQP D;  1K8A F;  5GAG F;  4UY8 F;  5GAH F;  2NRQ A;  4WCE D;  1YHQ D;  2WNY A;  4IOA D;  2PZZ A;  1VQN D;  3D7A A;  1KQS D;  4U67 D;  3PIO D;  1Q81 F;  3CMA D;  3CCL D;  5GAD F;  1VQK D;  1N8R F;  3CCV D;  1K9M F;  1M1K F;  3I56 D;  1VQ8 D;  2ZJQ D;  1Q82 F;  3G71 D;  1YI2 D;  1QVF D;  1VQ9 D;  2QEX D;  3CF5 D;  3CPW D;  4WFA D;  4WFN D;  1KC8 F; 
#chains in the Genus database with same CATH topology
 5MLC G;  2OTL D;  3CC7 D;  1VQ7 D;  3PIP D;  3CC4 D;  4IOC D;  3CCM D;  1JJ2 D;  1NJI F;  1YJ9 D;  3CXC D;  1QVG D;  1M90 F;  3CCS D;  3CCU D;  3CC2 D;  2OTJ D;  3C9G A;  1YJN D;  2NWU A;  3I55 D;  1K73 F;  5DM7 D;  5GAE F;  1W2B D;  1VQ4 D;  5H1S H;  3G4S D;  3CME D;  1MJI A;  2ZJP D;  3J7Z F;  3CD6 D;  3DLL D;  5HL7 D;  2OGK A;  3OW2 D;  1VQM D;  5DM6 D;  3G6E D;  3CCQ D;  1IQ4 A;  1VQL D;  5JVH D;  1YJW D;  4WF9 D;  1VQ6 D;  1YIT D;  1KD1 F;  1Q86 F;  1VQ5 D;  1Q7Y F;  1S72 D;  2QA4 D;  3CCJ D;  5JVG D;  2ZJR D;  4WFB D;  4IO9 D;  1YIJ D;  1VQO D;  3CCE D;  3CCR D;  1VQP D;  1K8A F;  5GAG F;  4UY8 F;  5GAH F;  2NRQ A;  4WCE D;  1YHQ D;  2WNY A;  4IOA D;  2PZZ A;  1VQN D;  3D7A A;  1KQS D;  4U67 D;  3PIO D;  1Q81 F;  3CMA D;  3CCL D;  5GAD F;  1VQK D;  1N8R F;  3CCV D;  1K9M F;  1M1K F;  3I56 D;  1VQ8 D;  2ZJQ D;  1Q82 F;  3G71 D;  1YI2 D;  1QVF D;  1VQ9 D;  2QEX D;  3CF5 D;  3CPW D;  4WFA D;  4WFN D;  1KC8 F; 
#chains in the Genus database with same CATH homology
 5MLC G;  2OTL D;  3CC7 D;  1VQ7 D;  3PIP D;  3CC4 D;  4IOC D;  3CCM D;  1JJ2 D;  1NJI F;  1YJ9 D;  3CXC D;  1QVG D;  1M90 F;  3CCS D;  3CCU D;  3CC2 D;  2OTJ D;  3C9G A;  1YJN D;  2NWU A;  3I55 D;  1K73 F;  5DM7 D;  5GAE F;  1W2B D;  1VQ4 D;  5H1S H;  3G4S D;  3CME D;  1MJI A;  2ZJP D;  3J7Z F;  3CD6 D;  3DLL D;  5HL7 D;  2OGK A;  3OW2 D;  1VQM D;  5DM6 D;  3G6E D;  3CCQ D;  1IQ4 A;  1VQL D;  5JVH D;  1YJW D;  4WF9 D;  1VQ6 D;  1YIT D;  1KD1 F;  1Q86 F;  1VQ5 D;  1Q7Y F;  1S72 D;  2QA4 D;  3CCJ D;  5JVG D;  2ZJR D;  4WFB D;  4IO9 D;  1YIJ D;  1VQO D;  3CCE D;  3CCR D;  1VQP D;  1K8A F;  5GAG F;  4UY8 F;  5GAH F;  2NRQ A;  4WCE D;  1YHQ D;  2WNY A;  4IOA D;  2PZZ A;  1VQN D;  3D7A A;  1KQS D;  4U67 D;  3PIO D;  1Q81 F;  3CMA D;  3CCL D;  5GAD F;  1VQK D;  1N8R F;  3CCV D;  1K9M F;  1M1K F;  3I56 D;  1VQ8 D;  2ZJQ D;  1Q82 F;  3G71 D;  1YI2 D;  1QVF D;  1VQ9 D;  2QEX D;  3CF5 D;  3CPW D;  4WFA D;  4WFN D;  1KC8 F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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