1ZFLA

Solution structure of iii-a, the major intermediate in the oxidative folding of leech carboxypeptidase inhibitor
Total Genus 4
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
67
structure length
67
Chain Sequence
GSHTPDESFLCYQPDQVCCFICRGAAPLPSEGECNPHPTAPWCREGAVEWVPYSTGQCRTTCIPYVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title NMR structural characterization and computational predictions of the major intermediate in oxidative folding of leech carboxypeptidase inhibitor
pubmed doi rcsb
molecule tags Hydrolase inhibitor
source organism Hirudo medicinalis
molecule keywords Metallocarboxypeptidase inhibitor
total genus 4
structure length 67
sequence length 67
ec nomenclature
pdb deposition date 2005-04-20
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1040.10 Alpha Beta 2-Layer Sandwich Carboxypeptidase Inhibitor; Chain A Carboxypeptidase inhibitor 1zflA00
1ZFIA 2ABZC 1ZFLA 1DTVA 1DTDB
chains in the Genus database with same CATH superfamily
3G2PA 3G2MA 1S3RA 3G2QA 3G2OA 4BIKA 1ZFLA 1DTVA 1DTDB 1M3JA 2ABZC 3HVNA 3CQFA 1ZFIA 1M3IA 1PFOA 3PJVD 4HSCX 3IF8B
chains in the Genus database with same CATH topology
1ZFIA 2ABZC 1ZFLA 1DTVA 1DTDB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZFI A;  2ABZ C;  1ZFL A;  1DTV A;  1DTD B; 
#chains in the Genus database with same CATH topology
 3G2P A;  3G2M A;  1S3R A;  3G2Q A;  3G2O A;  4BIK A;  1ZFL A;  1DTV A;  1DTD B;  1M3J A;  2ABZ C;  3HVN A;  3CQF A;  1ZFI A;  1M3I A;  1PFO A;  3PJV D;  4HSC X;  3IF8 B; 
#chains in the Genus database with same CATH homology
 1ZFI A;  2ABZ C;  1ZFL A;  1DTV A;  1DTD B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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