1E9TA

High resolution solution structure of human intestinal trefoil factor
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
59
structure length
59
Chain Sequence
EEYVGLSANQCAVPAKDRVDCGYPHVTPKECNNRGCCFDSRIPGVPWCFKPLQEAECTF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title High-Resolution Solution Structure of Human Intestinal Trefoil Factor and Functional Insights from Detailed Structural Comparisons with the Other Members of the Trefoil Family of Mammalian Cell Motility Factors
pubmed doi rcsb
molecule tags Cell motility factor
source organism Homo sapiens
molecule keywords INTESTINAL TREFOIL FACTOR
total genus 5
structure length 59
sequence length 59
ec nomenclature
pdb deposition date 2000-10-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00088 Trefoil Trefoil (P-type) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.110.10 Few Secondary Structures Irregular Spasmolytic Protein; domain 1 Spasmolytic Protein, domain 1 1e9tA00
3L4TA 2PSPA 3L4YA 3L4XA 1PE31 2QLYA 1HI7A 3L4UA 3TOPA 2QMJA 3LPPA 1PS2A 3TONA 3L4WA 3CTTA 1PCPA 3L4VA 3LPOA 3L4ZA 1E9TA 1PSPA
chains in the Genus database with same CATH superfamily
3L4TA 2PSPA 3L4YA 1XU6A 3L4XA 1PE31 2QLYA 1HI7A 3L4UA 3TOPA 2QMJA 3LPPA 1PS2A 3TONA 3L4WA 3CTTA 1PCPA 3L4VA 3LPOA 3L4ZA 1E9TA 1PSPA
chains in the Genus database with same CATH topology
3L4TA 2PSPA 3L4YA 3L4XA 1PE31 2QLYA 1HI7A 3L4UA 3TOPA 2QMJA 3LPPA 1PS2A 3TONA 3L4WA 3CTTA 1PCPA 3L4VA 3LPOA 3L4ZA 1E9TA 1PSPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3L4T A;  2PSP A;  3L4Y A;  3L4X A;  1PE3 1;  2QLY A;  1HI7 A;  3L4U A;  3TOP A;  2QMJ A;  3LPP A;  1PS2 A;  3TON A;  3L4W A;  3CTT A;  1PCP A;  3L4V A;  3LPO A;  3L4Z A;  1E9T A;  1PSP A; 
#chains in the Genus database with same CATH topology
 3L4T A;  2PSP A;  3L4Y A;  1XU6 A;  3L4X A;  1PE3 1;  2QLY A;  1HI7 A;  3L4U A;  3TOP A;  2QMJ A;  3LPP A;  1PS2 A;  3TON A;  3L4W A;  3CTT A;  1PCP A;  3L4V A;  3LPO A;  3L4Z A;  1E9T A;  1PSP A; 
#chains in the Genus database with same CATH homology
 3L4T A;  2PSP A;  3L4Y A;  3L4X A;  1PE3 1;  2QLY A;  1HI7 A;  3L4U A;  3TOP A;  2QMJ A;  3LPP A;  1PS2 A;  3TON A;  3L4W A;  3CTT A;  1PCP A;  3L4V A;  3LPO A;  3L4Z A;  1E9T A;  1PSP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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