1EGLA

The solution structure of eglin c based on measurements of many noes and coupling constants and its comparison with x-ray structures
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
70
structure length
70
Chain Sequence
TEFGSELKSFPEVVGKTVDQAREYFTLHYPQYDVYFLPEGSPVTLDLRYNRVRVFYNPGTNVVNHVPHVG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The solution structure of eglin c based on measurements of many NOEs and coupling constants and its comparison with X-ray structures.
pubmed rcsb
molecule keywords EGLIN C
molecule tags Proteinase inhibitor
source organism Hirudo medicinalis
total genus 9
structure length 70
sequence length 70
ec nomenclature
pdb deposition date 1993-09-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00280 potato_inhibit Potato inhibitor I family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.10.10 Alpha Beta 2-Layer Sandwich Trypsin Inhibitor V; Chain A Trypsin Inhibitor V, subunit A 1eglA00
1LW6I 1TO1I 1Y3BI 1VBWA 3W0DA 4B2BB 3RDZC 1CSEI 1TECI 3W0EA 1CISA 1Y34I 1COAI 1HYMA 2TECI 1YPBI 1TM5I 1SBNI 1MEEI 1Y3DI 1TM1I 1Y48I 5FFNI 3TECI 1DWMA 1TM4I 1EGLA 1YPAI 4B2AB 1TM3I 2CI2I 1MITA 1TM7I 1TO2I 5FBZB 4B1TB 2SNII 1TINA 1Y3CI 3RDYA 1Y4AI 1Y4DI 1ACBI 1Y1KI 1Y3FI 1SIBI 1Y33I 2SECI 4B2CB 1YPCI 4H4FB 1TMGI 3CI2A
chains in the Genus database with same CATH superfamily
5E10A 1LW6I 1TO1I 1Y3BI 1VBWA 2MGVA 3W0DA 4B2BB 3RDZC 1CSEI 1TECI 3W0EA 1CISA 1Y34I 1COAI 1HYMA 2KUIA 2TECI 1YPBI 1TM5I 1SBNI 1MEEI 1Y3DI 1TM1I 1Y48I 3PY9A 5FFNI 3TECI 1DWMA 2KUFA 1TM4I 1EGLA 1YPAI 4B2AB 1TM3I 2CI2I 1MITA 1TM7I 1TO2I 3CI2A 3M9GA 4B1TB 5FBZB 2SNII 5E0YA 1TINA 1Y3CI 3OUVA 3RDYA 1Y4AI 1Y4DI 1ACBI 1Y1KI 1Y3FI 1SIBI 1Y33I 2SECI 5E0ZA 4B2CB 1YPCI 2KUEA 4H4FB 1TMGI 2KUDA
chains in the Genus database with same CATH topology
1LW6I 1TO1I 1Y3BI 1VBWA 3W0DA 4B2BB 3RDZC 1CSEI 1TECI 3W0EA 1CISA 1Y34I 1COAI 1HYMA 2TECI 1YPBI 1TM5I 1SBNI 1MEEI 1Y3DI 1TM1I 1Y48I 5FFNI 3TECI 1DWMA 1TM4I 1EGLA 1YPAI 4B2AB 1TM3I 2CI2I 1MITA 1TM7I 1TO2I 5FBZB 4B1TB 2SNII 1TINA 1Y3CI 3RDYA 1Y4AI 1Y4DI 1ACBI 1Y1KI 1Y3FI 1SIBI 1Y33I 2SECI 4B2CB 1YPCI 4H4FB 1TMGI 3CI2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LW6 I;  1TO1 I;  1Y3B I;  1VBW A;  3W0D A;  4B2B B;  3RDZ C;  1CSE I;  1TEC I;  3W0E A;  1CIS A;  1Y34 I;  1COA I;  1HYM A;  2TEC I;  1YPB I;  1TM5 I;  1SBN I;  1MEE I;  1Y3D I;  1TM1 I;  1Y48 I;  5FFN I;  3TEC I;  1DWM A;  1TM4 I;  1EGL A;  1YPA I;  4B2A B;  1TM3 I;  2CI2 I;  1MIT A;  1TM7 I;  1TO2 I;  5FBZ B;  4B1T B;  2SNI I;  1TIN A;  1Y3C I;  3RDY A;  1Y4A I;  1Y4D I;  1ACB I;  1Y1K I;  1Y3F I;  1SIB I;  1Y33 I;  2SEC I;  4B2C B;  1YPC I;  4H4F B;  1TMG I;  3CI2 A; 
#chains in the Genus database with same CATH topology
 5E10 A;  1LW6 I;  1TO1 I;  1Y3B I;  1VBW A;  2MGV A;  3W0D A;  4B2B B;  3RDZ C;  1CSE I;  1TEC I;  3W0E A;  1CIS A;  1Y34 I;  1COA I;  1HYM A;  2KUI A;  2TEC I;  1YPB I;  1TM5 I;  1SBN I;  1MEE I;  1Y3D I;  1TM1 I;  1Y48 I;  3PY9 A;  5FFN I;  3TEC I;  1DWM A;  2KUF A;  1TM4 I;  1EGL A;  1YPA I;  4B2A B;  1TM3 I;  2CI2 I;  1MIT A;  1TM7 I;  1TO2 I;  3CI2 A;  3M9G A;  4B1T B;  5FBZ B;  2SNI I;  5E0Y A;  1TIN A;  1Y3C I;  3OUV A;  3RDY A;  1Y4A I;  1Y4D I;  1ACB I;  1Y1K I;  1Y3F I;  1SIB I;  1Y33 I;  2SEC I;  5E0Z A;  4B2C B;  1YPC I;  2KUE A;  4H4F B;  1TMG I;  2KUD A; 
#chains in the Genus database with same CATH homology
 1LW6 I;  1TO1 I;  1Y3B I;  1VBW A;  3W0D A;  4B2B B;  3RDZ C;  1CSE I;  1TEC I;  3W0E A;  1CIS A;  1Y34 I;  1COA I;  1HYM A;  2TEC I;  1YPB I;  1TM5 I;  1SBN I;  1MEE I;  1Y3D I;  1TM1 I;  1Y48 I;  5FFN I;  3TEC I;  1DWM A;  1TM4 I;  1EGL A;  1YPA I;  4B2A B;  1TM3 I;  2CI2 I;  1MIT A;  1TM7 I;  1TO2 I;  5FBZ B;  4B1T B;  2SNI I;  1TIN A;  1Y3C I;  3RDY A;  1Y4A I;  1Y4D I;  1ACB I;  1Y1K I;  1Y3F I;  1SIB I;  1Y33 I;  2SEC I;  4B2C B;  1YPC I;  4H4F B;  1TMG I;  3CI2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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