1YITD

Crystal structure of virginiamycin m and s bound to the 50s ribosomal subunit of haloarcula marismortui
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
165
structure length
140
Chain Sequence
FHEMREPRIEKVVVHMGIGHANAEDILGEITGQMPVRTKAKRTVGEFDIREGDPIGAKVTLRDEMAEEFLQTALPLAELATSQFDDTGNFSFGLDVTVNLVRPGYRVAKRDKASRSIPTKHRLNPADAVAFIESTYDVEV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Mlsbk Antibiotics Bound to Mutated Large Ribosomal Subunits Provide a Structural Explanation for Resistance.
pubmed doi rcsb
molecule tags Ribosome/antibiotic
molecule keywords 23S RIBOSOMAL RNA
total genus 18
structure length 140
sequence length 165
ec nomenclature
pdb deposition date 2005-01-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00281 Ribosomal_L5 Ribosomal protein L5
D PF00673 Ribosomal_L5_C ribosomal L5P family C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1440.10 Alpha Beta 2-Layer Sandwich 50s Ribosomal Protein L5; Chain: A, 50s Ribosomal Protein L5; Chain: A, 1yitD00
4WFBD 3CCQD 1YITD 1K8AF 5HL7D 2ZJRD 1VQKD 3CCED 5GAEF 1M90F 1YJ9D 2NWUA 1IQ4A 1VQ7D 1S72D 5GAGF 3CCJD 3CCUD 3CCLD 3CXCD 3CC2D 2OGKA 3G6ED 1Q81F 1W2BD 1VQ6D 3CCRD 2OTJD 1K73F 1YHQD 3J7ZF 2PZZA 1KD1F 3G4SD 3CF5D 1M1KF 3CD6D 1KC8F 2WNYA 3PIPD 1Q82F 2ZJQD 4UY8F 1VQOD 5DM6D 1K9MF 3CCSD 1QVFD 5MLCG 1Q86F 3CCVD 3CMED 2QEXD 1Q7YF 4WFAD 1JJ2D 4WCED 3CPWD 1QVGD 1YIJD 1MJIA 1VQ8D 2OTLD 1YI2D 1KQSD 1VQLD 2QA4D 4IOAD 3I55D 1N8RF 3G71D 4IOCD 3CCMD 4WFND 4U67D 4IO9D 3PIOD 1VQ9D 3CC7D 3I56D 1VQPD 1VQMD 1NJIF 2NRQA 3DLLD 3OW2D 1VQ4D 1VQ5D 3CC4D 3D7AA 5JVGD 3CMAD 5H1SH 2ZJPD 5GAHF 1VQND 5JVHD 1YJWD 3C9GA 1YJND 4WF9D 5DM7D 5GADF
chains in the Genus database with same CATH superfamily
4WFBD 3CCQD 1YITD 1K8AF 5HL7D 2ZJRD 1VQKD 3CCED 5GAEF 1M90F 1YJ9D 2NWUA 1IQ4A 1VQ7D 1S72D 5GAGF 3CCJD 3CCUD 3CCLD 3CXCD 3CC2D 2OGKA 3G6ED 1Q81F 1W2BD 1VQ6D 3CCRD 2OTJD 1K73F 1YHQD 3J7ZF 2PZZA 1KD1F 3G4SD 3CF5D 1M1KF 3CD6D 1KC8F 2WNYA 3PIPD 1Q82F 2ZJQD 4UY8F 1VQOD 5DM6D 1K9MF 3CCSD 1QVFD 5MLCG 1Q86F 3CCVD 3CMED 2QEXD 1Q7YF 4WFAD 1JJ2D 4WCED 3CPWD 1QVGD 1YIJD 1MJIA 1VQ8D 2OTLD 1YI2D 1KQSD 1VQLD 2QA4D 4IOAD 3I55D 1N8RF 3G71D 4IOCD 3CCMD 4WFND 4U67D 4IO9D 3PIOD 1VQ9D 3CC7D 3I56D 1VQPD 1VQMD 1NJIF 2NRQA 3DLLD 3OW2D 1VQ4D 1VQ5D 3CC4D 3D7AA 5JVGD 3CMAD 5H1SH 2ZJPD 5GAHF 1VQND 5JVHD 1YJWD 3C9GA 1YJND 4WF9D 5DM7D 5GADF
chains in the Genus database with same CATH topology
4WFBD 3CCQD 1YITD 1K8AF 5HL7D 2ZJRD 1VQKD 3CCED 5GAEF 1M90F 1YJ9D 2NWUA 1IQ4A 1VQ7D 1S72D 5GAGF 3CCJD 3CCUD 3CCLD 3CXCD 3CC2D 2OGKA 3G6ED 1Q81F 1W2BD 1VQ6D 3CCRD 2OTJD 1K73F 1YHQD 3J7ZF 2PZZA 1KD1F 3G4SD 3CF5D 1M1KF 3CD6D 1KC8F 2WNYA 3PIPD 1Q82F 2ZJQD 4UY8F 1VQOD 5DM6D 1K9MF 3CCSD 1QVFD 5MLCG 1Q86F 3CCVD 3CMED 2QEXD 1Q7YF 4WFAD 1JJ2D 4WCED 3CPWD 1QVGD 1YIJD 1MJIA 1VQ8D 2OTLD 1YI2D 1KQSD 1VQLD 2QA4D 4IOAD 3I55D 1N8RF 3G71D 4IOCD 3CCMD 4WFND 4U67D 4IO9D 3PIOD 1VQ9D 3CC7D 3I56D 1VQPD 1VQMD 1NJIF 2NRQA 3DLLD 3OW2D 1VQ4D 1VQ5D 3CC4D 3D7AA 5JVGD 3CMAD 5H1SH 2ZJPD 5GAHF 1VQND 5JVHD 1YJWD 3C9GA 1YJND 4WF9D 5DM7D 5GADF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WFB D;  3CCQ D;  1YIT D;  1K8A F;  5HL7 D;  2ZJR D;  1VQK D;  3CCE D;  5GAE F;  1M90 F;  1YJ9 D;  2NWU A;  1IQ4 A;  1VQ7 D;  1S72 D;  5GAG F;  3CCJ D;  3CCU D;  3CCL D;  3CXC D;  3CC2 D;  2OGK A;  3G6E D;  1Q81 F;  1W2B D;  1VQ6 D;  3CCR D;  2OTJ D;  1K73 F;  1YHQ D;  3J7Z F;  2PZZ A;  1KD1 F;  3G4S D;  3CF5 D;  1M1K F;  3CD6 D;  1KC8 F;  2WNY A;  3PIP D;  1Q82 F;  2ZJQ D;  4UY8 F;  1VQO D;  5DM6 D;  1K9M F;  3CCS D;  1QVF D;  5MLC G;  1Q86 F;  3CCV D;  3CME D;  2QEX D;  1Q7Y F;  4WFA D;  1JJ2 D;  4WCE D;  3CPW D;  1QVG D;  1YIJ D;  1MJI A;  1VQ8 D;  2OTL D;  1YI2 D;  1KQS D;  1VQL D;  2QA4 D;  4IOA D;  3I55 D;  1N8R F;  3G71 D;  4IOC D;  3CCM D;  4WFN D;  4U67 D;  4IO9 D;  3PIO D;  1VQ9 D;  3CC7 D;  3I56 D;  1VQP D;  1VQM D;  1NJI F;  2NRQ A;  3DLL D;  3OW2 D;  1VQ4 D;  1VQ5 D;  3CC4 D;  3D7A A;  5JVG D;  3CMA D;  5H1S H;  2ZJP D;  5GAH F;  1VQN D;  5JVH D;  1YJW D;  3C9G A;  1YJN D;  4WF9 D;  5DM7 D;  5GAD F; 
#chains in the Genus database with same CATH topology
 4WFB D;  3CCQ D;  1YIT D;  1K8A F;  5HL7 D;  2ZJR D;  1VQK D;  3CCE D;  5GAE F;  1M90 F;  1YJ9 D;  2NWU A;  1IQ4 A;  1VQ7 D;  1S72 D;  5GAG F;  3CCJ D;  3CCU D;  3CCL D;  3CXC D;  3CC2 D;  2OGK A;  3G6E D;  1Q81 F;  1W2B D;  1VQ6 D;  3CCR D;  2OTJ D;  1K73 F;  1YHQ D;  3J7Z F;  2PZZ A;  1KD1 F;  3G4S D;  3CF5 D;  1M1K F;  3CD6 D;  1KC8 F;  2WNY A;  3PIP D;  1Q82 F;  2ZJQ D;  4UY8 F;  1VQO D;  5DM6 D;  1K9M F;  3CCS D;  1QVF D;  5MLC G;  1Q86 F;  3CCV D;  3CME D;  2QEX D;  1Q7Y F;  4WFA D;  1JJ2 D;  4WCE D;  3CPW D;  1QVG D;  1YIJ D;  1MJI A;  1VQ8 D;  2OTL D;  1YI2 D;  1KQS D;  1VQL D;  2QA4 D;  4IOA D;  3I55 D;  1N8R F;  3G71 D;  4IOC D;  3CCM D;  4WFN D;  4U67 D;  4IO9 D;  3PIO D;  1VQ9 D;  3CC7 D;  3I56 D;  1VQP D;  1VQM D;  1NJI F;  2NRQ A;  3DLL D;  3OW2 D;  1VQ4 D;  1VQ5 D;  3CC4 D;  3D7A A;  5JVG D;  3CMA D;  5H1S H;  2ZJP D;  5GAH F;  1VQN D;  5JVH D;  1YJW D;  3C9G A;  1YJN D;  4WF9 D;  5DM7 D;  5GAD F; 
#chains in the Genus database with same CATH homology
 4WFB D;  3CCQ D;  1YIT D;  1K8A F;  5HL7 D;  2ZJR D;  1VQK D;  3CCE D;  5GAE F;  1M90 F;  1YJ9 D;  2NWU A;  1IQ4 A;  1VQ7 D;  1S72 D;  5GAG F;  3CCJ D;  3CCU D;  3CCL D;  3CXC D;  3CC2 D;  2OGK A;  3G6E D;  1Q81 F;  1W2B D;  1VQ6 D;  3CCR D;  2OTJ D;  1K73 F;  1YHQ D;  3J7Z F;  2PZZ A;  1KD1 F;  3G4S D;  3CF5 D;  1M1K F;  3CD6 D;  1KC8 F;  2WNY A;  3PIP D;  1Q82 F;  2ZJQ D;  4UY8 F;  1VQO D;  5DM6 D;  1K9M F;  3CCS D;  1QVF D;  5MLC G;  1Q86 F;  3CCV D;  3CME D;  2QEX D;  1Q7Y F;  4WFA D;  1JJ2 D;  4WCE D;  3CPW D;  1QVG D;  1YIJ D;  1MJI A;  1VQ8 D;  2OTL D;  1YI2 D;  1KQS D;  1VQL D;  2QA4 D;  4IOA D;  3I55 D;  1N8R F;  3G71 D;  4IOC D;  3CCM D;  4WFN D;  4U67 D;  4IO9 D;  3PIO D;  1VQ9 D;  3CC7 D;  3I56 D;  1VQP D;  1VQM D;  1NJI F;  2NRQ A;  3DLL D;  3OW2 D;  1VQ4 D;  1VQ5 D;  3CC4 D;  3D7A A;  5JVG D;  3CMA D;  5H1S H;  2ZJP D;  5GAH F;  1VQN D;  5JVH D;  1YJW D;  3C9G A;  1YJN D;  4WF9 D;  5DM7 D;  5GAD F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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