1YJND

Crystal structure of clindamycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
165
structure length
140
Chain Sequence
FHEMREPRIEKVVVHMGIGHANAEDILGEITGQMPVRTKAKRTVGEFDIREGDPIGAKVTLRDEMAEEFLQTALPLAELATSQFDDTGNFSFGLDVTVNLVRPGYRVAKRDKASRSIPTKHRLNPADAVAFIESTYDVEV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S Ribosomal RNA
total genus 20
structure length 140
sequence length 165
ec nomenclature
pdb deposition date 2005-01-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00281 Ribosomal_L5 Ribosomal protein L5
D PF00673 Ribosomal_L5_C ribosomal L5P family C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1440.10 Alpha Beta 2-Layer Sandwich 50s Ribosomal Protein L5; Chain: A, 50s Ribosomal Protein L5; Chain: A, 1yjnD00
3CCQD 4IOAD 3C9GA 1VQ5D 4UY8F 3CF5D 1Q7YF 1IQ4A 3G71D 3CCMD 4WFBD 3PIPD 1K8AF 1K73F 2ZJQD 1K9MF 1VQOD 1Q82F 5GAGF 4U67D 1N8RF 3CC2D 5JVGD 1QVGD 1Q81F 5MLCG 5DM6D 5GADF 1VQ8D 4IO9D 2OGKA 3DLLD 5JVHD 2ZJRD 3G6ED 1VQ9D 4WFAD 1JJ2D 3CD6D 3CC7D 1S72D 1VQKD 1Q86F 2PZZA 1VQ7D 1VQLD 1MJIA 1KC8F 2QEXD 1M1KF 5GAEF 1YJ9D 5DM7D 1VQND 3PIOD 2ZJPD 4WCED 1VQ4D 3CCED 4WFND 1VQPD 2NWUA 3CC4D 1VQ6D 3J7ZF 3CCJD 1YITD 3CCSD 3CCUD 3CMAD 1YJWD 2NRQA 4IOCD 3CCVD 2QA4D 1YJND 4WF9D 5GAHF 5HL7D 1YHQD 1KD1F 5H1SH 3CCLD 1NJIF 3OW2D 3CMED 1W2BD 2OTLD 3CPWD 3D7AA 3I55D 3CCRD 1M90F 1KQSD 2WNYA 1VQMD 3G4SD 3I56D 3CXCD 2OTJD 1YIJD 1QVFD 1YI2D
chains in the Genus database with same CATH superfamily
3CCQD 4IOAD 3C9GA 1VQ5D 4UY8F 3CF5D 1Q7YF 1IQ4A 3G71D 3CCMD 4WFBD 3PIPD 1K8AF 1K73F 2ZJQD 1K9MF 1VQOD 1Q82F 5GAGF 4U67D 1N8RF 3CC2D 5JVGD 1QVGD 1Q81F 5MLCG 5DM6D 5GADF 1VQ8D 4IO9D 2OGKA 3DLLD 5JVHD 2ZJRD 3G6ED 1VQ9D 4WFAD 1JJ2D 3CD6D 3CC7D 1S72D 1VQKD 1Q86F 2PZZA 1VQ7D 1VQLD 1MJIA 1KC8F 2QEXD 1M1KF 5GAEF 1YJ9D 5DM7D 1VQND 3PIOD 2ZJPD 4WCED 1VQ4D 3CCED 4WFND 1VQPD 2NWUA 3CC4D 1VQ6D 3J7ZF 3CCJD 1YITD 3CCSD 3CCUD 3CMAD 1YJWD 2NRQA 4IOCD 3CCVD 2QA4D 1YJND 4WF9D 5GAHF 5HL7D 1YHQD 1KD1F 5H1SH 3CCLD 1NJIF 3OW2D 3CMED 1W2BD 2OTLD 3CPWD 3D7AA 3I55D 3CCRD 1M90F 1KQSD 2WNYA 1VQMD 3G4SD 3I56D 3CXCD 2OTJD 1YIJD 1QVFD 1YI2D
chains in the Genus database with same CATH topology
3CCQD 4IOAD 3C9GA 1VQ5D 4UY8F 3CF5D 1Q7YF 1IQ4A 3G71D 3CCMD 4WFBD 3PIPD 1K8AF 1K73F 2ZJQD 1K9MF 1VQOD 1Q82F 5GAGF 4U67D 1N8RF 3CC2D 5JVGD 1QVGD 1Q81F 5MLCG 5DM6D 5GADF 1VQ8D 4IO9D 2OGKA 3DLLD 5JVHD 2ZJRD 3G6ED 1VQ9D 4WFAD 1JJ2D 3CD6D 3CC7D 1S72D 1VQKD 1Q86F 2PZZA 1VQ7D 1VQLD 1MJIA 1KC8F 2QEXD 1M1KF 5GAEF 1YJ9D 5DM7D 1VQND 3PIOD 2ZJPD 4WCED 1VQ4D 3CCED 4WFND 1VQPD 2NWUA 3CC4D 1VQ6D 3J7ZF 3CCJD 1YITD 3CCSD 3CCUD 3CMAD 1YJWD 2NRQA 4IOCD 3CCVD 2QA4D 1YJND 4WF9D 5GAHF 5HL7D 1YHQD 1KD1F 5H1SH 3CCLD 1NJIF 3OW2D 3CMED 1W2BD 2OTLD 3CPWD 3D7AA 3I55D 3CCRD 1M90F 1KQSD 2WNYA 1VQMD 3G4SD 3I56D 3CXCD 2OTJD 1YIJD 1QVFD 1YI2D
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CCQ D;  4IOA D;  3C9G A;  1VQ5 D;  4UY8 F;  3CF5 D;  1Q7Y F;  1IQ4 A;  3G71 D;  3CCM D;  4WFB D;  3PIP D;  1K8A F;  1K73 F;  2ZJQ D;  1K9M F;  1VQO D;  1Q82 F;  5GAG F;  4U67 D;  1N8R F;  3CC2 D;  5JVG D;  1QVG D;  1Q81 F;  5MLC G;  5DM6 D;  5GAD F;  1VQ8 D;  4IO9 D;  2OGK A;  3DLL D;  5JVH D;  2ZJR D;  3G6E D;  1VQ9 D;  4WFA D;  1JJ2 D;  3CD6 D;  3CC7 D;  1S72 D;  1VQK D;  1Q86 F;  2PZZ A;  1VQ7 D;  1VQL D;  1MJI A;  1KC8 F;  2QEX D;  1M1K F;  5GAE F;  1YJ9 D;  5DM7 D;  1VQN D;  3PIO D;  2ZJP D;  4WCE D;  1VQ4 D;  3CCE D;  4WFN D;  1VQP D;  2NWU A;  3CC4 D;  1VQ6 D;  3J7Z F;  3CCJ D;  1YIT D;  3CCS D;  3CCU D;  3CMA D;  1YJW D;  2NRQ A;  4IOC D;  3CCV D;  2QA4 D;  1YJN D;  4WF9 D;  5GAH F;  5HL7 D;  1YHQ D;  1KD1 F;  5H1S H;  3CCL D;  1NJI F;  3OW2 D;  3CME D;  1W2B D;  2OTL D;  3CPW D;  3D7A A;  3I55 D;  3CCR D;  1M90 F;  1KQS D;  2WNY A;  1VQM D;  3G4S D;  3I56 D;  3CXC D;  2OTJ D;  1YIJ D;  1QVF D;  1YI2 D; 
#chains in the Genus database with same CATH topology
 3CCQ D;  4IOA D;  3C9G A;  1VQ5 D;  4UY8 F;  3CF5 D;  1Q7Y F;  1IQ4 A;  3G71 D;  3CCM D;  4WFB D;  3PIP D;  1K8A F;  1K73 F;  2ZJQ D;  1K9M F;  1VQO D;  1Q82 F;  5GAG F;  4U67 D;  1N8R F;  3CC2 D;  5JVG D;  1QVG D;  1Q81 F;  5MLC G;  5DM6 D;  5GAD F;  1VQ8 D;  4IO9 D;  2OGK A;  3DLL D;  5JVH D;  2ZJR D;  3G6E D;  1VQ9 D;  4WFA D;  1JJ2 D;  3CD6 D;  3CC7 D;  1S72 D;  1VQK D;  1Q86 F;  2PZZ A;  1VQ7 D;  1VQL D;  1MJI A;  1KC8 F;  2QEX D;  1M1K F;  5GAE F;  1YJ9 D;  5DM7 D;  1VQN D;  3PIO D;  2ZJP D;  4WCE D;  1VQ4 D;  3CCE D;  4WFN D;  1VQP D;  2NWU A;  3CC4 D;  1VQ6 D;  3J7Z F;  3CCJ D;  1YIT D;  3CCS D;  3CCU D;  3CMA D;  1YJW D;  2NRQ A;  4IOC D;  3CCV D;  2QA4 D;  1YJN D;  4WF9 D;  5GAH F;  5HL7 D;  1YHQ D;  1KD1 F;  5H1S H;  3CCL D;  1NJI F;  3OW2 D;  3CME D;  1W2B D;  2OTL D;  3CPW D;  3D7A A;  3I55 D;  3CCR D;  1M90 F;  1KQS D;  2WNY A;  1VQM D;  3G4S D;  3I56 D;  3CXC D;  2OTJ D;  1YIJ D;  1QVF D;  1YI2 D; 
#chains in the Genus database with same CATH homology
 3CCQ D;  4IOA D;  3C9G A;  1VQ5 D;  4UY8 F;  3CF5 D;  1Q7Y F;  1IQ4 A;  3G71 D;  3CCM D;  4WFB D;  3PIP D;  1K8A F;  1K73 F;  2ZJQ D;  1K9M F;  1VQO D;  1Q82 F;  5GAG F;  4U67 D;  1N8R F;  3CC2 D;  5JVG D;  1QVG D;  1Q81 F;  5MLC G;  5DM6 D;  5GAD F;  1VQ8 D;  4IO9 D;  2OGK A;  3DLL D;  5JVH D;  2ZJR D;  3G6E D;  1VQ9 D;  4WFA D;  1JJ2 D;  3CD6 D;  3CC7 D;  1S72 D;  1VQK D;  1Q86 F;  2PZZ A;  1VQ7 D;  1VQL D;  1MJI A;  1KC8 F;  2QEX D;  1M1K F;  5GAE F;  1YJ9 D;  5DM7 D;  1VQN D;  3PIO D;  2ZJP D;  4WCE D;  1VQ4 D;  3CCE D;  4WFN D;  1VQP D;  2NWU A;  3CC4 D;  1VQ6 D;  3J7Z F;  3CCJ D;  1YIT D;  3CCS D;  3CCU D;  3CMA D;  1YJW D;  2NRQ A;  4IOC D;  3CCV D;  2QA4 D;  1YJN D;  4WF9 D;  5GAH F;  5HL7 D;  1YHQ D;  1KD1 F;  5H1S H;  3CCL D;  1NJI F;  3OW2 D;  3CME D;  1W2B D;  2OTL D;  3CPW D;  3D7A A;  3I55 D;  3CCR D;  1M90 F;  1KQS D;  2WNY A;  1VQM D;  3G4S D;  3I56 D;  3CXC D;  2OTJ D;  1YIJ D;  1QVF D;  1YI2 D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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